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A Phase III Randomized Trial of the Timing of...
Journal article

A Phase III Randomized Trial of the Timing of Meloxicam With Iodine-125 Prostate Brachytherapy

Abstract

PURPOSE: Nonsteroidal anti-inflammatory medication is used to reduce prostate edema and urinary symptoms following prostate brachytherapy. We hypothesized that a cyclooxygenase-2 (COX-2) inhibitor regimen started 1 week prior to seed implant might diminish the inflammatory response, thus reducing edema, retention rates, and symptom severity. METHODS AND MATERIALS: From March 2004 to February 2008, 316 men consented to an institutional review …

Authors

Crook J; Patil N; Wallace K; Borg J; Zhou D; Ma C; Pond G

Journal

International Journal of Radiation Oncology • Biology • Physics, Vol. 77, No. 2, pp. 496–501

Publisher

Elsevier

Publication Date

June 2010

DOI

10.1016/j.ijrobp.2009.04.078

ISSN

0360-3016