Phosphorylation Concept

subject area of

• 1,25-Dihydroxyvitamin D3 Stimulates Expression and Translocation of Protein Kinase Cα and Cδ via a Nongenomic Mechanism and Rapidly Induces Phosphorylation of a 33-kDa Protein in Acute Promyelocytic NB4 Cells  Journal Articles
• 1,25-Dihydroxyvitamin D3Primes Acute Promyelocytic Cells for TPA-Induced Monocytic Differentiation through Both PKC and Tyrosine Phosphorylation Cascades  Journal Articles
• Chlamydophila pneumoniae PknD Exhibits Dual Amino Acid Specificity and Phosphorylates Cpn0712, a Putative Type III Secretion YscD Homolog  Journal Articles
• AMPK β1 reduces tumor progression and improves survival in p53 null mice  Journal Articles
• Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis  Journal Articles
• PhoR autokinase activity is controlled by an intermediate in wall teichoic acid metabolism that is sensed by the intracellular PAS domain during the PhoPR‐mediated phosphate limitation response of Bacillus subtilis  Journal Articles
• A Deoxyribozyme with a Novel Guanine Quartet-Helix Pseudoknot Structure  Journal Articles
• A Novel Multi-Ingredient Supplement Activates a Browning Program in White Adipose Tissue and Mitigates Weight Gain in High-Fat Diet-Fed Mice  Journal Articles
• A Phase II Trial with Pharmacodynamic Endpoints of the Proteasome Inhibitor Bortezomib in Patients with Metastatic Colorectal Cancer  Journal Articles
• A Role of p73 in Mitotic Exit  Journal Articles
• A Single Session of Aerobic Exercise Mediates Plasticity-Related Phosphorylation in both the Rat Motor Cortex and Hippocampus  Journal Articles
• A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions  Journal Articles
• A novel inhibitor of Chlamydophila pneumoniae protein kinase D (PknD) inhibits phosphorylation of CdsD and suppresses bacterial replication  Journal Articles
• A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients.  Journal Articles
• A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas  Conferences
• A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leukemia: a NCIC (National Cancer Institute of Canada) Clinical Trials Group Study  Journal Articles
• AEG3482 Is an Antiapoptotic Compound that Inhibits Jun Kinase Activity and Cell Death through Induced Expression of Heat Shock Protein 70  Journal Articles
• AMP-Activated Protein Kinase Is Not Down-Regulated in Human Skeletal Muscle of Obese Females  Journal Articles
• AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5  Journal Articles
• AMP-activated protein kinase — the fat controller of the energy railroadThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.  Journal Articles
• AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment  Journal Articles
• AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice  Journal Articles
• AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation  Journal Articles
• AMPK-Dependent Inhibitory Phosphorylation of ACC Is Not Essential for Maintaining Myocardial Fatty Acid Oxidation  Journal Articles
• AMPK‐independent pathways regulate skeletal muscle fatty acid oxidation  Journal Articles
• ATM activation is accompanied with earlier stages of prostate tumorigenesis  Journal Articles
• ATM activity contributes to the tumor-suppressing functions of p14ARF  Journal Articles
• ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres  Journal Articles
• ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice  Journal Articles
• ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance  Journal Articles
• Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia  Journal Articles
• Abnormal perikaryal immunoreactivity to the phosphorylated heavy neurofilament unit in intracerebral basal forebrain transplants  Journal Articles
• Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression  Journal Articles
• Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes  Journal Articles
• Activated Neutrophils Induce Epithelial Cell Apoptosis Through Oxidant-Dependent Tyrosine Dephosphorylation of Caspase-8  Journal Articles
• Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts  Journal Articles
• Activation of mesangial cell MAPK in responseto homocysteine  Journal Articles
• Active Site Interference and Asymmetric Activation in the Chemotaxis Protein Histidine Kinase CheA  Journal Articles
• Acute Post-Exercise Myofibrillar Protein Synthesis Is Not Correlated with Resistance Training-Induced Muscle Hypertrophy in Young Men  Journal Articles
• Acute endurance exercise increases the nuclear abundance of PGC-1α in trained human skeletal muscle  Journal Articles
• Acyl Chain Dependence of Diacylglycerol Activation of Protein Kinase C Activityin Vitro  Journal Articles
• Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway  Journal Articles
• Adenovirus E1A under the control of heterologous promoters: Wide variation in E1A expression levels has little effect on virus replication  Journal Articles
• Adiponectin inhibits oxidative stress in human prostate carcinoma cells  Journal Articles
• Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats  Journal Articles
• Adrenergic regulation of HSL serine phosphorylation and activity in human skeletal muscle during the onset of exercise  Journal Articles
• Alterations of Membrane Phosphorylation in Erythrocyte Membranes from Patients with Duchenne Muscular Dystrophy  Journal Articles
• Alterations of erythrocyte ghost protein phosphorylation in the duchenne and myotonic muscular dystrophies  Journal Articles
• Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling  Journal Articles
• Aminoglycoside antibiotic phosphotransferases are also serine protein kinases  Journal Articles
• An Acidic Microenvironment Increases NK Cell Killing of Cryptococcus neoformans and Cryptococcus gattii by Enhancing Perforin Degranulation  Journal Articles
• An ESI‐MS/MS Method for Screening of Small‐Molecule Mixtures against Glycogen Synthase Kinase‐3β (GSK‐3β)  Journal Articles
• An Ultrasensitive Bacterial Motor Revealed by Monitoring Signaling Proteins in Single Cells  Journal Articles
• An auto-inhibited state of protein kinase G and implications for selective activation  Journal Articles
• An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp  Journal Articles
• Apoptosis Induced by p75NTR Overexpression Requires Jun Kinase-Dependent Phosphorylation of Bad  Journal Articles
• Aryl hydrocarbon receptor control of a disease tolerance defence pathway  Journal Articles
• Assessing the mechanistic target of rapamycin complex-1 pathway in response to resistance exercise and feeding in human skeletal muscle by multiplex assay  Journal Articles
• Association of Multiple Cellular Stress Pathways With Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-Deficient Mice  Journal Articles
• Association of Phosphorylated Epidermal Growth Factor Receptor with Survival in Patients with Locally Advanced Non-small Cell Lung Cancer Treated with Radiotherapy  Journal Articles
• BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation  Journal Articles
• BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis  Journal Articles
• Bacterial Chemotaxis: The motor connection  Journal Articles
• Beyond mitochondria: Alternative energy-producing pathways from all strata of life  Journal Articles
• Biological Activity of Nerve Growth Factor Precursor Is Dependent upon Relative Levels of Its Receptors  Journal Articles
• Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region  Journal Articles
• Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis  Journal Articles
• Body-weight-support treadmill training improves blood glucose regulation in persons with incomplete spinal cord injury  Journal Articles
• Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation  Journal Articles
• Both Traditional and Stair Climbing–based HIIT Cardiac Rehabilitation Induce Beneficial Muscle Adaptations  Journal Articles
• Brain-derived neurotrophic factor and TrkB expression in the “oldest-old,” the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta  Journal Articles
• Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1α in human skeletal muscle  Journal Articles
• Butein impairs the protumorigenic activity of malignant pleural mesothelioma cells  Journal Articles
• CARM1 drives mitophagy and autophagy flux during fasting-induced skeletal muscle atrophy  Journal Articles
• CREB expression mediates amyloid β-induced basal BDNF downregulation  Journal Articles
• CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection  Journal Articles
• Ca²⁺/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts  Journal Articles
• Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans  Journal Articles
• Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man  Journal Articles
• Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity  Journal Articles
• Carbon Monoxide–Releasing Molecule-401 Suppresses Polymorphonuclear Leukocyte Migratory Potential by Modulating F-Actin Dynamics  Journal Articles
• Caveolin-1 phosphorylation is required for stretch-induced EGFR and Akt activation in mesangial cells  Journal Articles
• Cdk-dependent phosphorylation regulates TRF1 recruitment to PML bodies and promotes C-circle production in ALT cells  Journal Articles
• Changes in HIF-1α protein, pyruvate dehydrogenase phosphorylation, and activity with exercise in acute and chronic hypoxia  Journal Articles
• Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor Receptor  Journal Articles
• Che‐1‐induced inhibition of mTOR pathway enables stress‐induced autophagy  Journal Articles
• Chinese hamster ovary cell mutants specifically affected in the phosphorylation of C-purine nucleosides  Journal Articles
• Chromatin Dynamics of Gene Activation and Repression in Response to Interferon α (IFNα) Reveal New Roles for Phosphorylated and Unphosphorylated Forms of the Transcription Factor STAT2  Journal Articles
• Chronic β₂-adrenoceptor stimulation impairs cardiac relaxation via reduced SR Ca²⁺-ATPase protein and activity  Journal Articles
• Ciliary Neurotrophic Factor Suppresses Hypothalamic AMP-Kinase Signaling in Leptin-Resistant Obese Mice  Journal Articles
• Colchicine attenuates renal injury in a model of hypertensive chronic kidney disease  Journal Articles
• Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1 and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity  Journal Articles
• Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress  Journal Articles
• Composition and Function of AP-1 Transcription Complexes during Muscle Cell Differentiation  Journal Articles
• Concurrent resistance and aerobic exercise stimulates both myofibrillar and mitochondrial protein synthesis in sedentary middle-aged men  Journal Articles
• Continuous infusion of neurotrophin-3 triggers sprouting, decreases the levels of TrkA and TrkC, and inhibits epileptogenesis and activity-dependent axonal growth in adult rats  Journal Articles
• Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase  Journal Articles
• Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3  Journal Articles
• Cooperative Interactions between Androgen Receptor (AR) and Heat-Shock Protein 27 Facilitate AR Transcriptional Activity  Journal Articles
• Creatine supplementation affects sprint endurance in juvenile rainbow trout  Journal Articles
• Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres  Journal Articles
• DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants  Journal Articles
• Decreased In Situ Insulin Receptor Dephosphorylation in Hyperglycemia-Induced Insulin Resistance in Rat Adipocytes  Journal Articles
• Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity  Journal Articles
• Determination of soluble CAMP-dependent protein kinase activity in guinea-pig tracheal smooth muscle  Journal Articles
• Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils  Journal Articles
• Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle  Journal Articles
• Diminished contraction‐induced intracellular signaling towards mitochondrial biogenesis in aged skeletal muscle  Journal Articles
• Dissociation of AMPK activity and ACCβ phosphorylation in human muscle during prolonged exercise  Journal Articles
• Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division  Journal Articles
• Dynamic Alterations to α-Actinin Accompanying Sarcomere Disassembly and Reassembly during Cardiomyocyte Mitosis  Journal Articles
• EGFR-PLCγ1 signaling mediates high glucose-induced PKCβ1-Akt activation and collagen I upregulation in mesangial cells  Journal Articles
• ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation  Journal Articles
• Early Intraplatelet Signaling Enhances the Release of Human Platelet PAR-1 and -4 Amino-Terminal Peptides in Response to Thrombin  Journal Articles
• Eccentric Exercise Activates Novel Transcriptional Regulation of Hypertrophic Signaling Pathways Not Affected by Hormone Changes  Journal Articles
• Effect of superoxide radical on Ca2+ pumps of coronary artery  Journal Articles
• Effects of Extracts from the CyanobacteriumMicrocystis aeruginosaon Ion Regulation and Gill Na⁺,K⁺‐ATPase and K⁺‐Dependent Phosphatase Activities of the Estuarine CrabChasmagnathus granulata(Decapoda, Grapsidae)  Journal Articles
• Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue  Journal Articles
• Effects of Plasma Adrenaline on Hormone‐Sensitive Lipase at Rest and during Moderate Exercise in Human Skeletal Muscle  Journal Articles
• Efficient UV repair requires disengagement of the CSB winged helix domain from the CSB ATPase domain  Journal Articles
• Emerging and divergent roles of pyrophosphorylated nucleotides in bacterial physiology and pathogenesis  Journal Articles
• Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis  Journal Articles
• Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction  Journal Articles
• Energy-stress-mediated AMPK activation inhibits ferroptosis  Journal Articles
• Enhanced Amino Acid Sensitivity of Myofibrillar Protein Synthesis Persists for up to 24 h after Resistance Exercise in Young Men1–3  Journal Articles
• Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662  Journal Articles
• Entrapment of Src Protein Tyrosine Kinase in Sugar-Modified Silica  Journal Articles
• Epidermal growth factor receptor-dependent activation of Gab1 is involved in ErbB-2-mediated mammary tumor progression  Journal Articles
• Establishing a relationship between prolactin and altered fatty acid β-Oxidation via carnitine palmitoyl transferase 1 in breast cancer cells  Journal Articles
• Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors  Journal Articles
• Evidence for the role of AMPK in regulating PGC‐1 alpha expression and mitochondrial proteins in mouse epididymal adipose tissue  Journal Articles
• Exercise, sex, menstrual cycle phase, and 17β-estradiol influence metabolism-related genes in human skeletal muscle  Journal Articles
• Exercise-specific adaptations in human skeletal muscle: Molecular mechanisms of making muscles fit and mighty.  Journal Articles
• Exploration of trade-offs between steady-state and dynamic properties in signaling cycles  Journal Articles
• Exposure to cigarette smoke suppresses IL-15 generation and its regulatory NK cell functions in poly I:C-augmented human PBMCs  Journal Articles
• Expression of recombinant human casein kinase II and recombinant heat shock protein 90 in Escherichia coli and characterization of their interactions.  Journal Articles
• Expression of the β4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells  Journal Articles
• Fatty acids stimulate AMP‐activated protein kinase and enhance fatty acid oxidation in L6 myotubes  Journal Articles
• Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis  Journal Articles
• Fish oil supplementation suppresses resistance exercise and feeding-induced increases in anabolic signaling without affecting myofibrillar protein synthesis in young men  Journal Articles
• Functionally important amino acids in Saccharomyces cerevisiae aspartate kinase  Journal Articles
• G Protein-coupled Receptor Kinase-mediated Desensitization of Metabotropic Glutamate Receptor 1A Protects against Cell Death  Journal Articles
• Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice  Journal Articles
• Gene Expression and Enzyme Activity of Mitochondrial Proteins in Irradiated Rainbow Trout (Oncorhynchus Mykiss, Walbaum) TissuesIn Vitro  Journal Articles
• Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model  Journal Articles
• Genome-wide lentiviral shRNA screen identifies serine/arginine-rich splicing factor 2 as a determinant of oncolytic virus activity in breast cancer cells  Journal Articles
• Glucose transporter expression in L6 muscle cells: Regulation through insulin- and stress-activated pathways  Journal Articles
• Guanosine promotes proliferation of neural stem cells through cAMP-CREB pathway.  Journal Articles
• Guanosine protects SH-SY5Y cells against β-amyloid-induced apoptosis  Journal Articles
• HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells  Journal Articles
• Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity  Journal Articles
• Heparan Sulfate Interacting Protein (HIP/L29) Negatively Regulates Growth Responses to Basic Fibroblast Growth Factor in Gingival Fibroblasts  Journal Articles
• Hepatic Glucose Intolerance Precedes Hepatic Steatosis in the Male Aromatase Knockout (ArKO) Mouse  Journal Articles
• High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2  Journal Articles
• High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry  Journal Articles
• Human airway smooth muscle promotes eosinophil differentiation  Journal Articles
• Huntingtin N17 domain is a reactive oxygen species sensor regulating huntingtin phosphorylation and localization  Journal Articles
• Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response  Journal Articles
• IL-10R Polymorphisms Are Associated with Very-early-onset Ulcerative Colitis  Journal Articles
• IL-4 and IL-13 Differentially Regulate TLR-Induced Eosinophil-Basophil Differentiation of Cord Blood CD34+ Progenitor Cells  Journal Articles
• Identification of the phosphorylation sites in early region 1A proteins of adenovirus type 5 by amino acid sequencing of peptide fragments.  Journal Articles
• Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion  Journal Articles
• Immunoassay for glial fibrillary acidic protein: Antigen recognition is affected by its phosphorylation state  Journal Articles
• Impact of SOCS3 overexpression on human skeletal muscle development in vitro  Journal Articles
• Impaired c-src activation and motility defects in PEA3-null fibroblasts  Journal Articles
• Impairment of pyruvate dehydrogenase activity by acetaldehyde  Journal Articles
• Increased skeletal muscle glucose uptake by rosemary extract through AMPK activation  Journal Articles
• Inflammation promotes adipocyte lipolysis via IRE1 kinase  Journal Articles
• Influenza Promotes Collagen Deposition via αvβ6 Integrin-mediated Transforming Growth Factor β Activation  Journal Articles
• Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men  Journal Articles
• Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma  Journal Articles
• Inhibition of adenosine kinase by phosphonate and bisphosphonate derivatives  Journal Articles
• Inhibition of intimal hyperplasia after stenting by over-expression of p15: A member of the INK4 family of cyclin-dependent kinase inhibitors  Journal Articles
• Inhibition of metabolic cooperation by phorbol esters in a cell culture system based on adenosine kinase deficient mutants of V79 cells  Journal Articles
• Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin  Journal Articles
• Insulin acutely decreases hepatic fatty acid synthase activity  Journal Articles
• Insulin, Insulin-like Growth Factor-I, and Platelet-Derived Growth Factor Activate Extracellular Signal-Regulated Kinase by Distinct Pathways in Muscle Cells  Journal Articles
• Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1  Journal Articles
• Interaction of c-Abl and p73α and their collaboration to induce apoptosis  Journal Articles
• Interactions between ROS and AMP kinase activity in the regulation of PGC-1α transcription in skeletal muscle cells  Journal Articles
• Involvement of adenosine kinase in the phosphorylation of formycin B in CHO cells  Journal Articles
• Involvement of the actin network in insulin signalling.  Conferences
• Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells  Journal Articles
• Jnk1 activity lowers the cellular production of H2O2 and modulates the growth arrest response to scavenging of H2O2 by catalase  Journal Articles
• Kinase inhibitors modulate huntingtin cell localization and toxicity  Journal Articles
• Kinase-specific responsiveness to incremental contractile activity in skeletal muscle with low and high mitochondrial content  Journal Articles
• Lipopolysaccharide core phosphates are required for viability and intrinsic drug resistance in Pseudomonas aeruginosa  Journal Articles
• Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions  Journal Articles
• Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms  Journal Articles
• Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells  Journal Articles
• Lysosomal and Proteasomal Degradation Play Distinct Roles in the Life Cycle of Cx43 in Gap Junctional Intercellular Communication-deficient and -competent Breast Tumor Cells  Journal Articles
• MAPping the kinase landscape of macrophage activation  Journal Articles
• MRE11–RAD50–NBS1 and ATM function as co-mediators of TRF1 in telomere length control  Journal Articles
• Making AppDNA using T4 DNA ligase  Journal Articles
• Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Death Receptor for Granzyme B during Cytotoxic T Cell–Induced Apoptosis  Journal Articles
• Massage Therapy Attenuates Inflammatory Signaling After Exercise-Induced Muscle Damage  Journal Articles
• Matched work high-intensity interval and continuous running induce similar increases in PGC-1α mRNA, AMPK, p38, and p53 phosphorylation in human skeletal muscle  Journal Articles
• Maternal nutrient restriction impairs young adult offspring ovarian signaling resulting in reproductive dysfunction and follicle loss†  Journal Articles
• Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix  Journal Articles
• Mechanical Strain-Induced RhoA Activation Requires NADPH Oxidase-Mediated ROS Generation in Caveolae  Journal Articles
• Mechanical stretch-induced RhoA activation is mediated by the RhoGEF Vav2 in mesangial cells  Journal Articles
• Mechanism of aminoglycoside 3'-phosphotransferase type IIIa: His188 is not a phosphate-accepting residue  Journal Articles
• Mechanisms underlying increases in SR Ca²⁺-ATPase activity after exercise in rat skeletal muscle  Journal Articles
• Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation  Journal Articles
• Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment  Journal Articles
• Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo  Journal Articles
• Microvesicles Contribute to the Bystander Effect of DNA Damage  Journal Articles
• Mitogen-activated protein kinases Erk1/2 and p38 are required for maximal regulation of TIMP-1 by oncostatin M in murine fibroblasts  Journal Articles
• Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate  Journal Articles
• Multiple Occurrences of an Efficient Self-Phosphorylating Deoxyribozyme Motif  Journal Articles
• Muscarinic acetylcholine receptor activation increases transcellular transport of macromolecules across mouse and human intestinal epithelium in vitro  Journal Articles
• Muscle‐specific AMPK β1β2‐null mice display a myopathy due to loss of capillary density in nonpostural muscles  Journal Articles
• Muscular and Systemic Correlates of Resistance Training-Induced Muscle Hypertrophy  Journal Articles
• Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop  Journal Articles
• Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition  Journal Articles
• Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine  Journal Articles
• Mutations inSYNGAP1Cause Intellectual Disability, Autism, and a Specific Form of Epilepsy by Inducing Haploinsufficiency  Journal Articles
• Myelin-Associated Glycoprotein Is a Myelin Signal that Modulates the Caliber of Myelinated Axons  Journal Articles
• Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts  Journal Articles
• Myotonic muscular dystrophy  Journal Articles
• N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation  Journal Articles
• NOD1 Activators Link Innate Immunity to Insulin Resistance  Journal Articles
• Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site  Journal Articles
• Negative Regulation of β4 Integrin Transcription by Homeodomain-Interacting Protein Kinase 2 and p53 Impairs Tumor Progression  Journal Articles
• Neotrofin, a novel purine that induces NGF-dependent nociceptive nerve sprouting but not hyperalgesia in adult rat skin  Journal Articles
• Nerve growth factor inhibitor with novel‐binding domain demonstrates nanomolar efficacy in both cell‐based and cell‐free assay systems  Journal Articles
• Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line  Journal Articles
• Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells  Journal Articles
• Nonphosphorylated neurofilament protein is expressed by scattered neurons in the human vestibular brainstem  Journal Articles
• Novel mutants of CHO cells resistant to adenosine analogs and containing biochemically altered form of adenosine kinase in cell extracts  Journal Articles
• O₂uptake kinetics, pyruvate dehydrogenase activity, and muscle deoxygenation in young and older adults during the transition to moderate-intensity exercise  Journal Articles
• Oligomeric Amyloid Decreases Basal Levels of Brain-Derived Neurotrophic factor (BDNF) mRNA via Specific Downregulation of BDNF Transcripts IV and V in Differentiated Human Neuroblastoma Cells  Journal Articles
• Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1  Journal Articles
• Opposing Functions of Akt Isoforms in Lung Tumor Initiation and Progression  Journal Articles
• PDH-E1α Dephosphorylation and Activation in Human Skeletal Muscle During Exercise  Journal Articles
• PGC‐1α gene expression is down‐regulated by Akt‐mediated phosphorylation and nuclear exclusion of FoxO1 in insulin‐stimulated skeletal muscle  Journal Articles
• PIKfyve: a new fish in the growing pool of AMPK substrates  Journal Articles
• PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells  Journal Articles
• POST-BURN HEPATIC INSULIN RESISTANCE IS ASSOCIATED WITH ENDOPLASMIC RETICULUM (ER) STRESS  Journal Articles
• Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans  Journal Articles
• Panax quinquefolium saponin combined with dual antiplatelet drugs inhibits platelet adhesion to injured HUVECs via PI3K/AKT and COX pathways  Journal Articles
• Parathyroid hormone-related protein induces fibronectin up-regulation in rat mesangial cells through reactive oxygen species/Src/EGFR signaling  Journal Articles
• Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation  Journal Articles
• Phosphorylated Derivatives That Activate or Inhibit Mammalian Adenosine Kinase Provide Insights into the Role of Pentavalent Ions in AK Catalysis  Journal Articles
• Phosphorylating DNA with DNA  Journal Articles
• Phosphorylation at the carboxy terminus of the 55-kilodalton adenovirus type 5 E1B protein regulates transforming activity  Journal Articles
• Phosphorylation of PITSLRE p110 Isoforms Accompanies Their Processing by Caspases during Fas-mediated Cell Death  Journal Articles
• Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivo  Journal Articles
• Phosphorylation of casein by human erythrocyte membrane-bound protein kinase: competition of casein with endogenous substrates  Journal Articles
• Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions  Journal Articles
• Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance  Journal Articles
• Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function  Journal Articles
• Plasma Membrane Calcium Pump Activity in Rat Pancreatic Islets: An Accurate Method to Measure its Calcium-Dependent Modulation  Journal Articles
• Post-translational modifications of TRF1 and TRF2 and their roles in telomere maintenance  Journal Articles
• Preexercise Aminoacidemia and Muscle Protein Synthesis after Resistance Exercise  Journal Articles
• Probing modifications of the neuronal cytoskeleton  Journal Articles
• Prodigious substrate specificity of AAC(6′)-APH(2′'), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci  Journal Articles
• Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARα and UCP2 expression in rats  Journal Articles
• Propranolol Improves Impaired Hepatic Phosphatidylinositol 3-Kinase/Akt Signaling after Burn Injury  Journal Articles
• Protective activity of guanosine in an in vitro model of Parkinson's disease.  Journal Articles
• Protein Ingestion Increases Myofibrillar Protein Synthesis after Concurrent Exercise  Journal Articles
• Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane  Journal Articles
• Protein kinase C α modulates liver X receptor α transactivation  Journal Articles
• Protein kinase activity immunoprecipitated from adenovirus infected cells by sera from tumor-bearing hamsters  Journal Articles
• Purification and characterization of VanR and the cytosolic domain of VanS: A two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147  Journal Articles
• RPS6 phosphorylation occurs to a greater extent in the periphery of human skeletal muscle fibers, near focal adhesions, after anabolic stimuli  Journal Articles
• Raloxifene, a Mixed Estrogen Agonist/Antagonist, Induces Apoptosis through Cleavage of BAD in TSU-PR1 Human Cancer Cells  Journal Articles
• Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise  Journal Articles
• Rapid and Specific Imaging of Extracellular Signaling Molecule Adenosine Triphosphate with a Self-Phosphorylating DNAzyme  Journal Articles
• Real-time fluorogenic kinase assay using protein as substrate  Journal Articles
• Receptor domains of two-component signal transduction systems  Journal Articles
• Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression  Journal Articles
• Reduced Socs3 expression in adipose tissue protects female mice against obesity-induced insulin resistance  Journal Articles
• Regiospecificity of Aminoglycoside Phosphotransferase from Enterococci and Staphylococci (APH(3‘)-IIIa)  Journal Articles
• Regulation and function of triacylglycerol lipases in cellular metabolism  Journal Articles
• Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue  Journal Articles
• Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M  Journal Articles
• Regulation of NADH/CoQ Oxidoreductase: Do Phosphorylation Events Affect Activity?  Journal Articles
• Regulation of Pyruvate Dehydrogenase (PDH) Activity in Human Skeletal Muscle During Exercise  Journal Articles
• Regulation of plasminogen activator inhibitor‐1 secretion by urokinase and tissue plasminogen activator in rat epithelioid‐type smooth muscle cells  Journal Articles
• Regulation of profibrotic responses by ADAM17 activation in high glucose requires its C-terminus and FAK  Journal Articles
• Regulation of the cell cycle in response to inhibition of mitochondrial generated energy  Journal Articles
• Regulatory control of DNA end resection by Sae2 phosphorylation  Journal Articles
• Regulatory properties of neuronal cdc2-like kinase  Journal Articles
• Relative Reduction of Endothelial Nitric-Oxide Synthase Expression and Transcription in Atherosclerosis-Prone Regions of the Mouse Aorta and in an in Vitro Model of Disturbed Flow  Journal Articles
• Relaxin alters cardiac myofilament function through a PKC-dependent pathway  Journal Articles
• Requirement and Redundancy of the Src Family Kinases Fyn and Lyn in Perforin-Dependent Killing of Cryptococcus neoformans by NK Cells  Journal Articles
• Requirement of p38 stress-activated MAP kinase for cell death in the developing retina depends on the stage of cell differentiation  Journal Articles
• Resistance exercise decreases eIF2Bε phosphorylation and potentiates the feeding-induced stimulation of p70^S6K1 and rpS6 in young men  Journal Articles
• Resistance exercise load does not determine training-mediated hypertrophic gains in young men  Journal Articles
• Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men  Journal Articles
• Response to Ticagrelor in Clopidogrel Nonresponders and Responders and Effect of Switching Therapies  Journal Articles
• RhoA Activation in Mesangial Cells by Mechanical Strain Depends on Caveolae and Caveolin-1 Interaction  Journal Articles
• Role of Tyrosine Phosphorylation in U46619-induced Vasoconstriction of Pulmonary Vasculature and Its Modulation by Genistein, Daidzein, and Equol  Journal Articles
• Rtt107 Is Required for Recruitment of the SMC5/6 Complex to DNA Double Strand Breaks  Journal Articles
• Sarcoplasmic reticulum Ca2+ pump in pig coronary artery smooth muscle is regulated by a novel pathway  Journal Articles
• Scavenging of Extracellular H2O2 by Catalase Inhibits the Proliferation of HER-2/Neu-transformed Rat-1 Fibroblasts through the Induction of a Stress Response  Journal Articles
• Secondary-Structure Characterization of Two Proficient Kinase Deoxyribozymes  Journal Articles
• Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion  Journal Articles
• Selective involvement of the PI3K/PKB/bad pathway in retinal cell death  Journal Articles
• Sequence Diversity, Metal Specificity, and Catalytic Proficiency of Metal-Dependent Phosphorylating DNA Enzymes  Journal Articles
• Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells  Journal Articles
• Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice  Journal Articles
• Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin  Journal Articles
• Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger?  Journal Articles
• Site-directed mutagenesis of the src gene of Rous sarcoma virus: construction and characterization of a deletion mutant temperature sensitive for transformation  Journal Articles
• Skeletal muscle metabolism is unaffected by DCA infusion and hyperoxia after onset of intense aerobic exercise  Journal Articles
• Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling  Journal Articles
• Small molecule functional discrimination of the kinases required for the microbial synthesis of threonine and isoleucine  Journal Articles
• Sodium bicarbonate ingestion augments the increase in PGC-1α mRNA expression during recovery from intense interval exercise in human skeletal muscle  Journal Articles
• Specific attenuation of protein kinase phosphorylation in muscle with a high mitochondrial content  Journal Articles
• Spectinomycin kinase from Legionella pneumophila. Characterization of substrate specificity and identification of catalytically important residues  Journal Articles
• Stability strengths oncogenic activity  Journal Articles
• StoPK-1, a serine/threonine protein kinase from the glycopeptide antibiotic producer Streptomyces toyocaensis NRRL 15009, affects oxidative stress response  Journal Articles
• Stretch-induced Raf-1 activation in mesangial cells requires actin cytoskeletal integrity  Journal Articles
• Structural and Kinetic Characterization of the LPS Biosynthetic Enzyme d-α,β-d-Heptose-1,7-bisphosphate Phosphatase (GmhB) from Escherichia coli,  Journal Articles
• Superoxide anion mediates angiotensin II-induced potentiation of contractile response to sympathetic stimulation  Journal Articles
• Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy.  Journal Articles
• Synthesis and Biological Activity of a Focused Library of Mitogen‐activated Protein Kinase Phosphatase Inhibitors  Journal Articles
• Synthesis and in Vitro Evaluation of¹⁸F- and¹⁹F-Labeled Insulin:  A New Radiotracer for PET-based Molecular Imaging Studies  Journal Articles
• Synthetic beta-turn peptides as substrates for a tyrosine protein kinase.  Journal Articles
• TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia  Journal Articles
• TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation  Journal Articles
• TRF1 phosphorylation on T271 modulates telomerase-dependent telomere length maintenance as well as the formation of ALT-associated PML bodies  Journal Articles
• Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology  Journal Articles
• Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model  Journal Articles
• Testosterone inhibits transforming growth factor-β signaling during myogenic differentiation and proliferation of mouse satellite cells: Potential role of follistatin in mediating testosterone action  Journal Articles
• The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase  Journal Articles
• The GDNF Target Vsnl1 Marks the Ureteric Tip  Journal Articles
• The Influence of Ser-154, Cys-113, and the Phosphorylated Threonine Residue on the Catalytic Reaction Mechanism of Pin1  Journal Articles
• The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels  Journal Articles
• The Suppressor of Cytokine Signaling 3 Inhibits Leptin Activation of AMP-Kinase in Cultured Skeletal Muscle of Obese Humans  Journal Articles
• The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades.  Journal Articles
• The antiapoptotic effect of guanosine is mediated by the activation of the PI 3‐kinase/AKT/PKB pathway in cultured rat astrocytes  Journal Articles
• The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation  Journal Articles
• The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs  Journal Articles
• The effects of brain-derived neurotrophic factor (BDNF) administration on kindling induction, Trk expression and seizure-related morphological changes  Journal Articles
• The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal  Journal Articles
• The major site of tyrosine phosphorylation in polyomavirus middle T antigen is not required for transformation  Journal Articles
• The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus  Journal Articles
• The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway  Journal Articles
• The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids  Journal Articles
• The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults  Journal Articles
• The role of interleukin‐4Rα in the induction of glutamic acid decarboxylase in airway epithelium following acute house dust mite exposure  Journal Articles
• Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia  Journal Articles
• Thermal Injury Activates the eEF2K‐Dependent eEF2 Pathway in Pediatric Patients  Journal Articles
• Toll‐like receptor‐mediated eosinophil–basophil differentiation: autocrine signalling by granulocyte–macrophage colony‐stimulating factor in cord blood haematopoietic progenitors  Journal Articles
• Transcriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein  Journal Articles
• Transplantation of Fetal CNS Tissue Into the Peripheral Nervous System:A Model to Study Aberrant Changes in the Neuronal Cytoskeleton  Journal Articles
• Treatment with atorvastatin ameliorates hepatic very[ndash ]low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: Evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity  Journal Articles
• Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2  Journal Articles
• Turning a Kinase Deoxyribozyme into a Sensor  Journal Articles
• Type IV pilins regulate their own expression via direct intramembrane interactions with the sensor kinase PilS  Journal Articles
• Tyrosine 740 Phosphorylation of Discoidin Domain Receptor 2 by Src Stimulates Intramolecular Autophosphorylation and Shc Signaling Complex Formation  Journal Articles
• Tyrosine Phosphorylation of Caspase-8 Abrogates Its Apoptotic Activity and Promotes Activation of c-Src  Journal Articles
• Tyrosine phosphorylation and cadherin/catenin function  Journal Articles
• Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo  Journal Articles
• Up-regulation of Hsp27 Plays a Role in the Resistance of Human Colon Carcinoma HT29 Cells to Photooxidative Stress¶  Journal Articles
• VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats  Journal Articles
• Velocity-Difference Induced Focusing of Nucleotides in Capillary Electrophoresis with a Dynamic pH Junction  Journal Articles
• Voluntary physical activity and leucine correct impairments in muscle protein synthesis in partially pancreatectomised rats  Journal Articles
• Wild-Type p53 Induces Diverse Effects in 32D Cells Expressing Different Oncogenes  Journal Articles
• XRCC4's interaction with XLF is required for coding (but not signal) end joining  Journal Articles
• cAMP response element–binding protein is expressed at high levels in human ovarian adenocarcinoma and regulates ovarian tumor cell proliferation  Journal Articles
• p73 Is Regulated by Phosphorylation at the G2/M Transition  Journal Articles