Journal article
An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp
Abstract
Bacteria have evolved sophisticated mechanisms to inhibit the growth of competitors1. One such mechanism involves type VI secretion systems, which bacteria can use to inject antibacterial toxins directly into neighbouring cells. Many of these toxins target the integrity of the cell envelope, but the full range of growth inhibitory mechanisms remains unknown2. Here we identify a type VI secretion effector, Tas1, in the opportunistic pathogen …
Authors
Ahmad S; Wang B; Walker MD; Tran H-KR; Stogios PJ; Savchenko A; Grant RA; McArthur AG; Laub MT; Whitney JC
Journal
Nature, Vol. 575, No. 7784, pp. 674–678
Publisher
Springer Nature
Publication Date
November 2019
DOI
10.1038/s41586-019-1735-9
ISSN
0028-0836