Journal article
An Ultrasensitive Bacterial Motor Revealed by Monitoring Signaling Proteins in Single Cells
Abstract
Understanding biology at the single-cell level requires simultaneous measurements of biochemical parameters and behavioral characteristics in individual cells. Here, the output of individual flagellar motors in Escherichia coli was measured as a function of the intracellular concentration of the chemotactic signaling protein. The concentration of this molecule, fused to green fluorescent protein, was monitored with fluorescence correlation …
Authors
Cluzel P; Surette M; Leibler S
Journal
Science, Vol. 287, No. 5458, pp. 1652–1655
Publisher
American Association for the Advancement of Science (AAAS)
Publication Date
March 3, 2000
DOI
10.1126/science.287.5458.1652
ISSN
0036-8075