selected scholarly activity
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chapters
- Update in Pediatric Hematology. 429-446. 2023
- Chapter 150 Disorders of Coagulation in the Neonate. 2189-2200.e1. 2018
- Disorders of Coagulation in the Neonate. 2189-2200.e1. 2018
- Update in Pediatric Hematology. 313-330. 2018
- Disorders of Coagulation in the Neonate. 2189-2200.e1. 2017
- Epidemiology, etiology, and pathophysiology of infection-associated venous thromboembolism in children. 88-106. 2014
- The Unique Challenges of Hemostatic Testing in Children. 77-91. 2013
- Antithrombin–Heparin Complexes. 1-42. 2013
- Polymeric Biomaterials. 1-42. 2013
- Polymeric Biomaterials. 1-42. 2013
- Thromboembolic Events at Specific Organ Sites. 163-178. 2013
- Neonatal thrombocytopenia: Etiology and management. 125-195. 2012
- Central Venous Line-related Thrombosis. 91-103. 2012
- Cerebral Sinovenous Thrombosis in Children with Cancer. 83-90. 2012
- Thromboembolism in Children with Cancer. 71-81. 2012
- Anticoagulation in Children. 237-252. 2009
- Pediatric Thrombosis. 120-123. 2008
- Improving Blood Compatibility of Biomaterials Using a Novel Antithrombin–Heparin Covalent Complex. 535-572. 2008
- Antithrombin-Heparin Complexes 2001
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conferences
- Prevalence of Thromboembolic Events in Children with Nephrotic Syndrome: A Systematic Review and Meta-Analysis. Pediatric Nephrology. 2473-2473. 2023
- EVIDENCE OF ENDOTHELIAL ACTIVATION INDUCED BY LEUKEMIC BLASTS IN A COCULTURE SYSTEM. American Journal of Hematology. E109-E110. 2023
- NEUROCOGNITIVE AND NEUROLOGICAL OUTCOMES IN CHILDREN WITH HEMOPHILIA B ARE UNAFFECTED BY LONG-TERM EXPOSURE TO NONACOG BETA PEGOL (N9-GP). American Journal of Hematology. E17-E18. 2023
- Hemostatic Profile at Diagnosis in Childhood Acute Lymphoblastic Leukemia: A Meta-Analysis of Cases from the Literature. Blood. 11581-11582. 2022
- EPIDEMIOLOGY OF CENTRAL VENOUS LINE (CVL) DYSFUNCTION IN CHILDREN WITH CANCER: RESULTS OF A PROVINCIAL PROSPECTIVE COHORT STUDY. Pediatric Blood and Cancer. S336-S337. 2022
- CANADIAN CLINICAL EXPERIENCE ON SWITCHING FROM OCTOCOG ALFA TO EXTENDED-HALF-LIFE FVIII DAMOCTOCOG ALFA PEGOL IN PATIENTS WITH SEVERE HAEMOPHILIA A. Haemophilia. 43-43. 2022
- ECONOMIC COST OF IN CANADA: A MULTI-CENTRE, RETROSPECTIVE STUDY. Value in Health. S93-S93. 2022
- Efficacy of rFVIIIFc for First-Time Immune Tolerance Induction (ITI) Therapy: Final Results from the Global, Prospective VerITI-8 Study. Blood. 2021
- Anti-FVIII Antibody and Inhibitor Development Patterns in Hemophilia A Mouse Models: A Systematic Review. Blood. 2402-2402. 2019
- Epidemiology, Diagnosis and Management of Neonatal Thrombosis. Blood. 3656-3656. 2019
- Routine Double Filtration Plasmapheresis Affects Hemostatic Proteins and Prolongs Clotting Tests. Blood. 1178-1178. 2019
- RFVIIIFC FOR FIRST-TIME IMMUNE TOLERANCE INDUCTION (ITI) THERAPY: INTERIM RESULTS FROM THE GLOBAL, PROSPECTIVE VERITI-8 STUDY. Haematologica. 8-8. 2019
- Early Postpartum Perineal Repair or C-Section Suture Removal Reduces Pain Without Wound Complications [7J]. Obstetrics and Gynecology. 108S-108S. 2019
- Mediastinal Mass, Triglycerides Level Above 1000mg/Dl and Intensive Dexamethasone and Asparaginase Treatment Are Risk Factors for Cerebral Sinus Venous Thrombosis in Children Treated for Acute Lymphoblastic Leukemia at the Children's Cancer Center of Lebanon. Blood. 5163-5163. 2018
- Challenges in Undertaking a Multi-Center Prospective, Observational, Cohort Study in the Pediatric Oncology Population. Pediatric Blood and Cancer. S497-S498. 2018
- A tale of two cities - comparison of perioperative practices for placement of Central Venous Access Devices (CVAD) in paediatric haemophilia patients. Haemophilia. 87-88. 2018
- Quadriceps hematoma in mild hemophilia after sport injury: Case series in two subjects. Haemophilia. 190-190. 2018
- Study of fibrin clot ultrastructure of varying concentrations of FVIII deficient plasma using scanning electron microscopy. Haemophilia. 54-55. 2018
- High compliance to prophylaxis regimens in adult and paediatric hemophilia B patients receiving RIX-FP in clinical studies. Haemophilia. 64-64. 2018
- Mortality After Pediatric Arterial Ischemic Stroke: Results From the International Paediatric Stroke Study. Stroke. 2018
- International Survey of the Management of Disseminated Intravascular Coagulation Among Pediatric and Neonatal Health Care Practitioners. Pediatric Blood and Cancer. S9-S9. 2017
- Inhibitor Development in Previously Untreated Patients with Severe Haemophilia a Treated with Human-CL RHFVIII, a New Generation Recombinant FVIII of Human Origin. Haemophilia. 24-+. 2017
- Elucidating the Thrombogenic Risk of Non-O Blood Groups in Children with Acute Lymphoblastic Leukemia (ALL): Is Von Willebrand Factor a Culprit ?. Blood. 4990-4990. 2016
- Inhibitor Development in Previously Untreated Patients with Severe Hemophilia a Treated with Nuwiq®, a New Generation Recombinant FVIII of Human Origin. Blood. 327-327. 2016
- Baseline Clinical and Laboratory Features Predict Risk of Developing Symptomatic Thromboembolism (STE) During Antileukemic Therapy in Children with De Novo Acute Lymphoblastic Leukemia (ALL). Pediatric Blood and Cancer. S27-S27. 2016
- NEONATAL PORTAL VEIN THROMBOSIS: A SINGLE INSTITUTIONAL EXPERIENCE OF SHORT AND LONG-TERM OUTCOMES. European Journal of Pediatrics. 1765-1766. 2016
- EFFECTS OF FONDAPARINUX AND RIVAROXABAN ON CLOT FORMATION IN FACTOR VIII-DEFICIENT, BUT VON WILLEBRAND FACTOR-SUPPLEMENTED, PLASMA MIMICKING PLASMA SAMPLES OBTAINED FROM HEMOPHILIA A PATIENTS. American Journal of Hematology. E409-E409. 2016
- Adherence and the relationship to frequency of infusions in pediatric patients with hemophilia A and B. Haemophilia. 7-7. 2016
- Central venous access device (CVAD) insertion procedure for pediatric patients with severe hemophilia A: trends in Factor VIII (FVIII) replacement therapy. Haemophilia. 97-98. 2016
- Point of care ultrasonography in hemophilia: impact of prior experience and success on competency assessment/evaluation. Haemophilia. 107-107. 2016
- Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (RIX-FP) in Previously Treated Children with Hemophilia B: Efficacy and Safety from a Phase 3 Pivotal Clinical Trial. Haemophilia. 22-23. 2016
- Effect of Asparaginase and Dexamethasone on FVIIa-at Complex and F1.2 in Children with Acute Lymphoblastic Leukemia: Evidence of Hypercoagulable State. Blood. 3552-3552. 2015
- Serum Ferritin Is Not Sensitive or Specific for the Diagnosis of Iron Deficiency in Patients with Normocytic Anemia. Blood. 955-955. 2015
- Supplementation to Treat Antithrombin Deficiency Improves Sensitivity to Heparin, Anticoagulation and Decreased Thrombogenecity in Neonates and Infants Undergoing Cardiac Surgery With Cardiopulmonary Bypass. Circulation. 2015
- Active thrombin assay for improved treatment of thrombosis. Journal of Thrombosis and Haemostasis. 295-295. 2015
- Between a rock and a hard place: conundrums in the management of cerebral sinovenous thrombosis (CSVT) in children with acute lymphoblastic leukemia (ALL)/lymphoma. Journal of Thrombosis and Haemostasis. 551-552. 2015
- Comparing FEIBA with recombinant FVIIA for reversal of rivaroxaban with a modified anti-Xa assay in undiluted Plasma. Journal of Thrombosis and Haemostasis. 389-389. 2015
- Comparison of factor IX glycosylation in different age groups. Journal of Thrombosis and Haemostasis. 319-320. 2015
- Development and validation of a Java-based computer program for image analysis of fibrin ultrastructure. Journal of Thrombosis and Haemostasis. 238-238. 2015
- Development of a rivaroxaban dosing regimen for treatment of VTE in children aged 12 to 18 years. Journal of Thrombosis and Haemostasis. 37-38. 2015
- Discordance between activated partial thromboplastin time and heparin level measured with anti-Xa assay in antithrombin-deficient plasma. Journal of Thrombosis and Haemostasis. 803-803. 2015
- Do preterm infants with patent ductus arteriosus (PDA) who fail indomethacin treatment have lower platelet counts?: a systematic review and meta-analysis. Journal of Thrombosis and Haemostasis. 422-423. 2015
- Efficacy, pharmacokinetics (PK) and safety results of a phase 3 clinical study of recombinant fusion protein linking coagulation factor IX with albumin (RIX-FP) in previously treated children with hemophilia B. Journal of Thrombosis and Haemostasis. 227-228. 2015
- Feasibility and safety of enoxaparin whole milligram dosing in premature and term neonates. Journal of Thrombosis and Haemostasis. 668-669. 2015
- Impact of inherited and acquired prothrombotic defects (PD) on the development of symptomatic thromboembolism (STE) in children with acute lymphoblastic leukemia (ALL) treated according to the Dana-Farber Cancer Institute (DFCI) 05-01 All-Therapy Protocol. Journal of Thrombosis and Haemostasis. 428-429. 2015
- Increasing platelets and other measures enhancing hemostasis are both important to prevent bleeding episodes when thrombocytopenic patients requiring antithrombotic therapy - a review of the medical literature. Journal of Thrombosis and Haemostasis. 810-810. 2015
- Inhibition of fibrinolysis by heparin, low molecular weight heparin and a novel anticoagulant, antithrombin-heparin covalent complex (ATH). Journal of Thrombosis and Haemostasis. 674-675. 2015
- Low dose rivaroxaban for secondary prophylaxis after full anticoagulation in patients with venous thromboembolism. Journal of Thrombosis and Haemostasis. 637-638. 2015
- Molecular modeling of a novel mutation in the SERPINC1 gene associated with type 1 antithrombin deficiency. Journal of Thrombosis and Haemostasis. 704-704. 2015
- Over-representation of severe subclavian vein occlusion in the affected arm, compared with the contralateral arm, in patients with unprovoked unilateral upper extremity deep vein thrombosis. Journal of Thrombosis and Haemostasis. 477-477. 2015
- Reversal of dabigatran could be achieved by hemodialysis with or without other hemostatic agents. Journal of Thrombosis and Haemostasis. 878-878. 2015
- The effect of age on glycan microheterogeneity of human Alpha-2-macroglobulin. Journal of Thrombosis and Haemostasis. 632-632. 2015
- The laboratory profile that predicts favorable outcome after Eculizumab therapy in patients with clinical features compatible with atypical hemolytic uremic syndrome. Journal of Thrombosis and Haemostasis. 712-712. 2015
- Utilization of anti-inhibitors products and inhibitors status of severe hemophilia patients: 5 years national data from the Canadian hemophilia assessment and resource management system. Journal of Thrombosis and Haemostasis. 362-362. 2015
- Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease. Blood. 841-841. 2014
- Iron Deficiency As a Common Treatable Cause of Chronic Normocytic Anemia. Blood. 4032-4032. 2014
- FEASIBILITY AND SAFETY OF FULL DOSE ANTICOAGULATION THERAPY (ACT) IN CHILDREN TREATED ACCORDING TO DANA-FARBER CANCER INSTITUTE (DFCI) ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) CONSORTIUM THERAPY PROTOCOLS. Pediatric Blood and Cancer. S170-S171. 2014
- IS THERE A ROLE FOR THROMBOPROPHYLAXIS IN PEDIATRIC SARCOMA PATIENTS? A LITERATURE REVIEW FOCUSING ON EPIDEMIOLOGY, RISK FACTORS AND OUTCOMES OF THROMBOEMBOLISM IN SARCOMA PATIENTS. Pediatric Blood and Cancer. S270-S270. 2014
- SYMPTOMATIC THROMBOSIS IN LEBANESE CHILDREN WITH CANCER TREATED AT A TERTIARY CARE CENTER. Pediatric Blood and Cancer. S351-S351. 2014
- AN IN VITROMODEL USING THROMBOELASTOGRAPHY TO EXAMINE THE EFFECTS OF HEPARIN ON CLOT FORMATION IN PLATELET-DEPLETED WHOLE BLOOD. American Journal of Hematology. E16-E16. 2014
- PATIENTS WITH THROMBOTIC THROMBOCYTOPENIC PURPURA ASSOCIATED WITH INHIBITORS TO ADAMTS13 RESPONDED SLOWER TO PLASMA EXCHANGE THAN THOSE WITHOUT INHIBITOR: A SYSTEMATIC REVIEW OF THE LITERATURE. American Journal of Hematology. E19-E20. 2014
- USE OF EXTENDED HALF-LIFE FACTOR IX PRODUCTS IN REPRESENTATIVE PAEDIATRIC PATIENTS WITH SEVERE FACTOR IX DEFICIENCY. American Journal of Hematology. E96-E96. 2014
- Assessment of patient preferences and perceived value of the comprehensive interdisciplinary combined hemophilia and orthopedic clinic using a validated questionnaire. Haemophilia. 146-146. 2014
- Factor VII deficiency patients: 5 years factors concentrates utilization trend based on the Canadian Hemophilia Assessment and Resource Management System (CHARMS). Haemophilia. 105-105. 2014
- Factor XIII (FXIII) deficiency in Canada: Description of the National Cohort. Haemophilia. 101-101. 2014
- Fifteen years of Canadian "tailored" prophylaxis: Results from the Canadian Hemophilia Primary Prophylaxis Study (CHPS). Haemophilia. 94-94. 2014
- Pharmacokinetics (PK) of recombinant and plasma-derived factor IX (FIX) products in pediatric patients with severe hemophilia B. Haemophilia. 92-92. 2014
- Physiotherapy and point of care ultrasonography in the management of hemophilia: Training phase. Haemophilia. 154-154. 2014
- What is known about care of a newborn with hemophilia?. Haemophilia. 146-146. 2014
- Your inhibitor treatment plan and you: Is your treatment working for you?. Haemophilia. 176-176. 2014
- A systematic review to evaluate thromboelastography for characterization of bleeding patients with advanced liver diseases. Journal of Thrombosis and Haemostasis. 229-229. 2013
- An in vitro model studying the effects of rivaroxaban and dabigatran on clot formation in factor VIII-depleted plasma mimicking the plasma of hemophilia A patients. Journal of Thrombosis and Haemostasis. 196-196. 2013
- Clinical presentation and molecular basis of congenital antithrombin deficiency in children: a cohort study. Journal of Thrombosis and Haemostasis. 389-390. 2013
- Covalently linking heparin to antithrombin diminishes the protective effect of fibrin on plasmin. Journal of Thrombosis and Haemostasis. 792-793. 2013
- Effect of ethanol locks on occlusion of central venous catheters used for administration of total parenteral nutrition. Journal of Thrombosis and Haemostasis. 386-386. 2013
- Heterogeneity of bleeding classification among randomized studies in hemophilic patients. Journal of Thrombosis and Haemostasis. 667-668. 2013
- In vitro assessment of the effect of dabigatran on thrombosis of adult and neonatal plasma using thromboelastography. Journal of Thrombosis and Haemostasis. 388-388. 2013
- Over-representation of thoracic outlet obstruction in patients with unprovoked upper extremity deep vein thrombosis. Journal of Thrombosis and Haemostasis. 1124-1125. 2013
- Procoagulant red blood cells diminish the protective effect of prothrombinase on factor Xa inhibition by fondaparinux and low molecular weight heparin. Journal of Thrombosis and Haemostasis. 461-461. 2013
- Protamine sulfate neutralization of anticoagulation by a potent antithrombin-heparin covalent complex. Journal of Thrombosis and Haemostasis. 462-463. 2013
- Subcutaneous injection of enoxaparin in neonates. Journal of Thrombosis and Haemostasis. 1202-1202. 2013
- The effect of rivaroxaban and dabigatran on the surface architecture of clots formed from plasma enriched with different levels of autologous platelets. Journal of Thrombosis and Haemostasis. 468-469. 2013
- The rate of reduction in D-dimer level for patients with venous thromboembolism responding to antithrombotic therapy. Journal of Thrombosis and Haemostasis. 703-704. 2013
- Utilization of FXIII concentrates by FXIII deficiency patients in Canadian hemophilia treatments centers: 10 years national data from the canadian hemophilia assessment and resource management system. Journal of Thrombosis and Haemostasis. 587-587. 2013
- MANAGEMENT OF FXIII DEFICIENCY: A REVIEW OF THE LITERATURE. Pediatric Blood and Cancer. S37-S37. 2013
- CEREBRAL SINO-VENOUS THROMBOSIS IN CHILDREN RECEIVING ANTILEUKEMIC THERAPY. Pediatric Blood and Cancer. 972-973. 2012
- A Systematic Review Evaluating the Effects of Treatment Duration on Bleeding Due to Factor-specific Oral Anticoagulant Therapy. Blood. 3417-3417. 2012
- An in-Vitro Model Using Thromboelastography to Evaluate the Effects of Anticoagulants On Clot Formation in Plasma Enriched with Autologous Platelets. Blood. 1091-1091. 2012
- Combination of Dexamethasone and Asparaginase Induces Prothrombotic State in Children Receiving Multiagent Chemotherapy for Acute Lymphoblastic Leukemia. Blood. 3536-3536. 2012
- Inhibition of Platelet-Prothrombianse by a Covalent Antithrombin-Heparin Complex.. Blood. 2212-2212. 2012
- Interactions of Heparin and a Covalently Linked Antithrombin Heparin Complex with the Components of the Fibrinolytic Pathway.. Blood. 2211-2211. 2012
- Glycolytic Regulation of the Plasma Membrane Ca2+ ATPase in Pancreatic Ductal Adenocarcinoma. Pancreas. 1369-1369. 2012
- Central venous line insertion and factor replacement therapy in patients with hemophilia A: A local experience. Haemophilia. 147-147. 2012
- Low bone mineral density and increased fat mass in boys with severe hemophilia. Haemophilia. 23-23. 2012
- Nutritional intake and bone mineral density in boys with severe hemophilia. Haemophilia. 23-23. 2012
- Osteochondral Lesions of the Ankle Joint in Patients with Hemophilia A: A Retrospective Case Series. Haemophilia. 128-128. 2012
- Pharmacokinetics (PK) of recombinant and plasma-derived factor VIII (FVIII) products in pediatric patients with severe hemophilia A. Haemophilia. 35-35. 2012
- Physical activity measured by high-frequency accelerometry in boys with hemophilia. Haemophilia. 192-192. 2012
- The Canadian experience: Severe factor V deficiency. Haemophilia. 184-185. 2012
- Understanding Health and Treatment Decision-Making among Youth with Hemophilia: A Qualitative Approach. Haemophilia. 207-207. 2012
- What do Canadian men living with hemophilia need to know to facilitate optimal disease management? A mixed methods approach. Haemophilia. 175-175. 2012
- An In Vitro Model to Study the Effect of Anticoagulants On Clot Formation in Platelet-Enriched Plasma. American Journal of Hematology. S170-S171. 2012
- Understanding Health and Treatment Decision-Making among Youth with Severe Hemophilia: a Qualitative Approach. International Journal of Qualitative Methods. 791-792. 2012
- Co-Administration Therapy Modulates Immunity to FVIII In Hemophilia A Mice. Blood. 547-548. 2011
- Exploring the Impact of Clinical Anticoagulants on Venous Thrombosis Stability Using a Novel Intravital Murine Model. Blood. 558-558. 2011
- Inhibition of Red Blood Cell-Prothrombinase by Heparin and a Covalent Antithrombin-Heparin Complex. Blood. 532-533. 2011
- A thromboelastography study to evaluate the effect of thrombocytopenia on clot formation in the presence of unfractionated heparin. Journal of Thrombosis and Haemostasis. 636-636. 2011
- Anticoagulant therapy in patients with thrombocytopenia: a systematic review of case series in medical literature. Journal of Thrombosis and Haemostasis. 636-637. 2011
- Body mass index and thromboembolism in children with hematological malignancies. Journal of Thrombosis and Haemostasis. 643-643. 2011
- Comparison of glycosylation profiles in various recombinant FVIII products and the effect of B-domain deletion. Journal of Thrombosis and Haemostasis. 356-356. 2011
- Development of a new immuno-activity assay for quantification of alpha-2-macroglobulin complexes. Journal of Thrombosis and Haemostasis. 108-108. 2011
- Developmental effects on the glycosylation of anticoagulant protein C. Journal of Thrombosis and Haemostasis. 104-104. 2011
- Dosing decisions in severe hemophilia a: can we aim lower? FVIII use in a cohort of Canadian patients in 2009. Journal of Thrombosis and Haemostasis. 681-681. 2011
- Enhanced inhibition of platelet-prothrombinase by covalent antithrombin-heparin complex. Journal of Thrombosis and Haemostasis. 365-365. 2011
- First analysis of 10-year trend in national factor concentrates usage in hemophilia: data from the Canadian hemophilia assessment and resource management system. Journal of Thrombosis and Haemostasis. 744-745. 2011
- Impact of persistent antiphospholipid antibodies on symptomatic thromboembolism in children: a systematic review & meta-analysis [observational studies]. Journal of Thrombosis and Haemostasis. 514-514. 2011
- Induction of endothelial von Willebrand's factor expression by precursor B lymphoblasts. Journal of Thrombosis and Haemostasis. 909-909. 2011
- Inhibition of coagulation factors by covalent antithrombin-heparin in the presence of endothelium. Journal of Thrombosis and Haemostasis. 575-575. 2011
- Mechanism of inhibition of the prothrombinase complex by a covalent antithrombin-heparin conjugate. Journal of Thrombosis and Haemostasis. 277-277. 2011
- Polyurethane immobilized with a covalent antithrombin-heparin complex for reducing thrombosis on blood contacting devices. Journal of Thrombosis and Haemostasis. 191-191. 2011
- Reversal of dabigatran using recombinant activated factor vii and activated prothrombin complex concentrates in thromboelastography assay. Journal of Thrombosis and Haemostasis. 576-577. 2011
- Thrombotic complications and thromboprophylaxis in single ventricle heart palliation in children. Journal of Thrombosis and Haemostasis. 766-767. 2011
- Thrombus persistence and thrombotic-related complications after pediatric cardiac surgery. Journal of Thrombosis and Haemostasis. 891-892. 2011
- Neurocognitive function (NCF) in patients (pts) treated with chemo/bio-radiotherapy (C/B-RT) for head and neck cancers (HNC).. Journal of Clinical Oncology. 2011
- Impact of Persistent Antiphospholipid Antibodies on Symptomatic Thromboembolism In Children: A Systematic Review & Meta-Analysis [Observational Studies]. Blood. 1303-1303. 2010
- Adherence with hemophilia treatments in Canada: a survey of hemophilia healthcare professionals. Haemophilia. 12-13. 2010
- Change in bone mineral density in patients with severe hemophilia A and B between the ages of 20 and 50: a pilot study. Haemophilia. 22-22. 2010
- Comprehensive care team approach to bleeding disorder patient care: benefits of team meeting. Haemophilia. 12-12. 2010
- Evaluation of neonatal hemostasis. Haemophilia. 16-16. 2010
- Mixing studies: use of specific factor-deficient plasma allows for confirmation of a single factor deficiency as the cause of an elevated APTT. Haemophilia. 85-85. 2010
- The year in review: describing prophylaxis and adherence in children with severe hemophilia A using patient infusion diaries. Haemophilia. 125-125. 2010
- Covalent Antithrombin-Heparin Complex Catalysis of Activated Protein C Inhibition by Protein C Inhibitor. Blood. 1229-1229. 2009
- Distribution and Clinical Signs of Venous, Arterial and Intracardiac Clots After Pediatric Cardiac Surgery. Blood. 1534-1534. 2009
- Impact of Thrombophilia On Arterial Ischemic Stroke or Cerebral Venous Sinus Thromboses in Children: A Systematic Review & Meta-Analysis of Observational Studies. Blood. 1534-1535. 2009
- Investigation Into Mechanisms of Prothrombinase Complex Inhibition by a Covalent Antithrombin-Heparin Complex. Blood. 840-841. 2009
- Association Between Longer Blood Conservation and Worse Post-Operative Outcomes in Pediatric Cardiac Surgery. Circulation. S568-S568. 2009
- Association Between Thromboembolic Complications and Increased Mortality After Pediatric Cardiac Surgery. Circulation. S557-S557. 2009
- Influence of Heparin Brand on Immediate Post-Operative Outcomes in Children Undergoing Cardiac Surgery. Circulation. S557-S557. 2009
- DECREASED OVERALL SURVIVAL AND INCREASED RISK OF THROMBOSIS IN CHILDREN WITH CANCER AND CENTRAL VENOUS LINE (CVL) DYSFUNCTION. Pediatric Blood and Cancer. 850-850. 2009
- Anticoagulant mechanisms of antithrombin-heparin studied by TEG. Journal of Thrombosis and Haemostasis. 685-685. 2009
- Biomaterial surface modification with an antithrombin-heparin covalent complex for improved intravascular devices. Journal of Thrombosis and Haemostasis. 1078-1078. 2009
- Comparison of recombinant and plasma-derived antithrombin biodistribution in vivo. Journal of Thrombosis and Haemostasis. 383-383. 2009
- Covalent antithrombin-heparin and the protein C pathway. Journal of Thrombosis and Haemostasis. 978-978. 2009
- Covalent linkage of heparin to antithrombin increases lung cell proliferation. Journal of Thrombosis and Haemostasis. 691-691. 2009
- Covalently linking antithrombin to heparin enhances the inhibition of FXa in the prothrombinase complex. Journal of Thrombosis and Haemostasis. 686-686. 2009
- Decreased overall survival and increased risk of thrombosis in children with cancer and central venous line (CVL) dysfunction. Journal of Thrombosis and Haemostasis. 1100-1100. 2009
- Development of factor V Leiden brochure. Journal of Thrombosis and Haemostasis. 771-771. 2009
- Does heterogeneity in measured calibrated thrombin generation assay or FVIII activity (<1%) explain clinical heterogeneity in severe hemophilia A?. Journal of Thrombosis and Haemostasis. 189-189. 2009
- Elevated levels of FVIIa-at following prednisone monotherapy in children with newly diagnosed acute lymphoblastic leukemia. Journal of Thrombosis and Haemostasis. 486-486. 2009
- Equivalency of Tinzaparin and Enoxaparin children: a single centre report on efficacy and safety. Journal of Thrombosis and Haemostasis. 1086-1086. 2009
- Experience of treating pediatric venous thromboembolism with low molecular weight heparin (LMWH) in an institute lack of anti-Xa monitoring support. Journal of Thrombosis and Haemostasis. 1080-1080. 2009
- Filter fracture and migration of a Gunther Tulip retrievable inferior vena cava filter 22 days after in a pediatric patient: a case report. Journal of Thrombosis and Haemostasis. 462-462. 2009
- Long term (10 year) results from the canadian hemophilia primary prophylaxis study. Journal of Thrombosis and Haemostasis. 54-55. 2009
- Long-term bleeding history as a tool for hemophilia management. Journal of Thrombosis and Haemostasis. 810-810. 2009
- Modelling thrombin generation in developmental hemostasis. Journal of Thrombosis and Haemostasis. 235-235. 2009
- Neonates: are they more prone to clotting or bleeding?. Journal of Thrombosis and Haemostasis. 98-98. 2009
- Novel heparin cofactor II-dermatan sulfate covalent complex formation selects for dermatan sulfate with higher molecular weight. Journal of Thrombosis and Haemostasis. 685-685. 2009
- Production of VWF may mediate lymphoblast induced thrombin activation in children with newly diagnosed ALL. Journal of Thrombosis and Haemostasis. 798-798. 2009
- Right atrial thrombosis in infants and children: literature review from 1981 to 2008. Journal of Thrombosis and Haemostasis. 724-724. 2009
- Risk factors of bleeding severity in young boys with severe hemophilia a on tailored prophylaxis: long-term (10-year) results from the Canadian hemophilia primary prophylaxis study. Journal of Thrombosis and Haemostasis. 814-814. 2009
- Selective detection of free plasmin using a chromogenic substrate bound to agarose beads. Journal of Thrombosis and Haemostasis. 130-130. 2009
- Systematic literature review of iliac vein compression syndrome in pediatric patients. Journal of Thrombosis and Haemostasis. 776-776. 2009
- Surface modification with an antithrombin-heparin covalent complex. 8th World Biomaterials Congress 2008. 1917. 2008
- Age-Related Differences in the Glycosylation of Anticoagulant Protein. Blood. 708-708. 2008
- Circulating Blasts Are Associated with High Levels of vWF and Thrombin Activation in Children with Newly Diagnosed ALL. Blood. 642-643. 2008
- Individualized Heparin and Protamine Management Protocol in Infants Undergoing Cardiopulmonary Bypass for Cardiac Surgery Improves Immediate Post-operative Clinical Outcomes. Circulation. S750-S750. 2008
- A survey of factor prophylaxis in Canadian patients with hemophilia. Haemophilia. 100-100. 2008
- Launch of toll free telephone line. Haemophilia. 132-132. 2008
- Impact of Inherited Thrombophilia on Symptomatic Venous Thrombo-Embolism (VTE) in Children: A Systematic Review & Meta-Analysis of 37 Studies Including 2470 Pediatric Patients.. Blood. 3189-3189. 2007
- Inhibition of the thrombin-thrombomodulin by a covalent antithrombin heparin. Blood. 791A-791A. 2007
- Risk factors predisposing to thromboembolism in children with cancer. Blood. 487A-487A. 2007
- Does mediastinal lymphadenopathy increase the risk of thromboembolism in children with lymphoma?. Pediatric Blood and Cancer. 618-618. 2007
- Dosing and safety of unfractionated heparin in infants with thrombotic complications. Pediatric Blood and Cancer. 642-643. 2007
- Impact of a novel covalent antithrombin-heparin (ATH) on gene expression during epithelial branching of the developing mouse lung. Pediatric Blood and Cancer. 628-628. 2007
- Impact of covalent anithrombin-heparin on vascularization in the developing lung. Pediatric Blood and Cancer. 643-643. 2007
- Outcomes ofthrombolysis for repeated courses of systemic tissue plasminogen activator for intravascular thrombosis in children. Haematologica. 122-122. 2007
- Suboptimal dosing of enoxaparin in preterm infants. Pediatric Blood and Cancer. 628-628. 2007
- Small bowel carcinoid (ECCell) neoplasia exhibits TGF B1-mediated regulatory abnormalities including up-regulation of C-myc and Mta1. Gastroenterology. A310-A310. 2007
- Hemorrhagic transformation of arterial ischemic stroke in children. Stroke. 581-581. 2007
- Thrombolysis in children with arterial ischemic stroke: Initial results from the international pediatric stroke study. Stroke. 485-485. 2007
- Implications of Heparinoid-Induced Inactivation of Coagulation Cascade Factors and In Vivo Proenzyme Concentration.. Blood. 1621-1621. 2006
- Inhibition of Factor Xa in Prothrombinase Is Enhanced by Covalent Linkage of Antithrombin to Heparin.. Blood. 1613-1613. 2006
- A Novel Inherited Platelet Function Disorder Involving the Thromboxane A2 Pathway of Platelet Activation.. Blood. 2175-2175. 2005
- Quantitiative Analysis of Roughness of Catheters by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM).. Blood. 3218-3218. 2005
- Thromboembolism in children with sarcoma.. Blood. 108B-108B. 2005
- Undetected factor VIII level in a type III von Willebrand disease (vWD) patient masquerading as severe hemophilia. Blood. 104B-104B. 2005
- Children on long term warfarin have decreased bone mineral density. Bone. S85-S85. 2005
- A Ten Year Survey of Chronic Immune Thrombocytopenic Purpura in Canadian Children, 1984–2003: Report of the Canadian Chronic ITP Working Group.. Blood. 3935-3935. 2004
- An Attempt to Reach Consensus Regarding Management of Neonatal Renal Vein Thrombosis: The Canadian Pediatric Hemostasis and Thrombosis Network Experience.. Blood. 4026-4026. 2004
- Continuous Versus Subsampling Analysis of Thrombin Generation.. Blood. 3886-3886. 2004
- Effect of Covalently-Bound Heparin on Insertion of the Reactive Centre Loop in Antithrombin.. Blood. 1783-1783. 2004
- Inhibition of factor Xa in prothrombinase is enhanced by covalent linkage of antithrombin to heparin. Blood. 299A-300A. 2004
- Reaction of Fibrin-Bound Thrombin with a Covalent Antithrombin-Heparin Complex Results in an Anticoagulant Surface.. Blood. 1848-1848. 2004
- Significant Differences in Neutralization of Heparin and Its Low Molecular Fragments by Protamine Sulfate: An In Vivo Study.. Blood. 1850-1850. 2004
- The Use of Aprotinin to Reduce Transfusion Requirements in Children Undergoing Cardiac Surgery: A Meta-Analysis.. Blood. 2718-2718. 2004
- Venous thrombosis in children. Revue Medicale Libanaise. 160-173. 2004
- Thromboembolism (TE) in children with acute lymphoblastic leukemia (ALL) treated on Dana Farber Cancer Institute (DFCI) protocols: Effect of dose and type (prednisone versus dexamethasone) of steroids used.. Journal of Clinical Oncology. 805S-805S. 2004
- Long term outcome of angiographic abnormalities in children with cranio-cervical arterial dissection. Stroke. E277-E277. 2004
- Predictors of recurrent thrombo-embolic events in 1745 infants and children with cerebral Sinovenous thrombosis: Results from the Canadian registry. Stroke. E234-E234. 2004
- Keparin for prevention of central line thrombosis: How much and how?. Pediatric Research. 552A-552A. 2004
- Increased anticardiolipin antibody IgG titers do not predict recurrent stroke or TIA in children. Neurology. 194-200. 2004
- A study of platelet response to aspirin in children with arterial ischemic stroke utilizing the PFA 100 Analyzer. Stroke. 308-308. 2004
- Clinical challenges in pediatric ischemic stroke: Data on over 1000 children with stroke from the 1-800-NO-CLOTS consultation service. Annals of Neurology. S98-S98. 2004
- Plavix (clopidogrel) in pediatric stroke: Monitoring of side effects and parent education strategies.. Stroke. 284-284. 2004
- Does low molecular weight heparin give a high aluminium load?. Blood. 128B-128B. 2003
- Novel antithrombotic drug reduces arterial Doppler high intensity transient signals during and after hypothermic cardiopulmonary bypass in pigs. Circulation. 433-433. 2003
- Neurological outcome in survivors of neonatal arterial ischemic stroke. Pediatric Research. 537A-537A. 2003
- Recanalization of neonatal cerebral sinovenous thrombosis: A follow-up study. Pediatric Research. 537A-537A. 2003
- Reversal of low molecular weight heparin (LMWH) prior to invasive procedures using subcutaneous unfractionated heparin in children with an ongoing high risk for thrombrosis. Pediatric Research. 294A-294A. 2003
- Reversal of warfarin or low molecular weight heparin (Lmwh) using subcutaneous unfractionated heparin (UFH) in pediatric outpatients with an ongoing high risk for thrombosis and requiring invasive procedures: A prospective cohort study of 146 children. Pediatric Research. 285A-285A. 2003
- Trimming of peripherally inserted central venous catheters may increase the risk of thrombosis. Pediatric Research. 454A-455A. 2003
- Very low dose warfarin for primary and secondary prophylaxis in children: A prospective cohort study of 20 children. Pediatric Research. 294A-294A. 2003
- Recurrent stroke: the role of prothrombotic disorders. Annals of Neurology. S110-S110. 2003
- Control of plasma thrombin generation on fetal distal lung epithelium by covalent serpin-heparinoid complexes.. Blood. 499A-499A. 2002
- Efficacy of aspirin treatment in pediatric stroke patients as measured with the PFA-100.. Blood. 279A-280A. 2002
- Natural history of arterial and venous thrombosis in children treated with low molecular weight heparin: A longitudinal study by Doppler ultrasound.. Blood. 278A-278A. 2002
- The Influence of age on in vitro plasmin generation in the presence of fibrin monomer. Blood. 93B-94B. 2002
- Covalent antithrombin-heparin complex (ATH): An alternative to heparin for arterial thrombosis prevention.. Blood. 48A-48A. 2001
- Chickenpox and Stroke in Childhood. Stroke. 1257-1262. 2001
- Effectiveness of reconstituted and then frozen tPA for dysfunctional percutaneous dialysis catheters.. Blood. 92B-92B. 2000
- Factor V Leiden and arterial ischemic stroke in children: A meta-analysis.. Blood. 645A-+. 2000
- Sulfate density of the low molecular weight heparins determine their protamine neutralizability.. Blood. 649A-649A. 2000
- Decreased bone density in children on long term warfarin therapy: A cross sectional study. Pediatric Research. 251A-251A. 2000
- Fibrinolytic response to venous occlusion is reduced in children with Kawasaki disease or hyperlipidemia. Pediatric Research. 247A-247A. 2000
- Incomplete neutralization of low molecular weight heparin by protamine is due to decreased binding affinity. Pediatric Research. 248A-248A. 2000
- Analysis of plasma thrombin activatable fibrinolysis inhibitor in a young population pre and post venous occlusion.. Blood. 85B-85B. 1999
- Dose finding and pharmacokinetics of prophylactic doses of a low molecular weight heparin (reviparin (TM)) in pediatric patients.. Blood. 27A-27A. 1999
- Fibrinolytic response to venous occlusion is reduced in children with Kawasaki disease or hyperlipidemia.. Blood. 235A-235A. 1999
- Stabilty and sterility of recombinant tissue plasminogen activator under-39 degrees C.. Blood. 24A-24A. 1999
- Use of tissue plasminogen activator to clear blocked central venous lines in pediatric patients: A prospective cohort study.. Blood. 25A-25A. 1999
- Comparison of inhibition of thrombin generation in newborn, child or adult plasmas by different heparinoids. Thrombosis and Haemostasis. 451-451. 1999
- Effect of chemotherapeutic agents on the regulation of thrombin by endothelial cells. Thrombosis and Haemostasis. 811-811. 1999
- Incomplete neutralization of low molecular weight heparin by protamine results from decreased binding affinity. Thrombosis and Haemostasis. 451-452. 1999
- Influence of factor VIIa concentrates on thrombin generation in full term and preterm neonates. Thrombosis and Haemostasis. 759-760. 1999
- Covalent heparin cofactor II heparin and heparin cofactor II dermatan sulfate complexes: Characterization of novel anticoagulants. Blood. 358A-358A. 1998
- Investigation of the anticoagulant mechanisms of a covalent antithrombin-heparin complex.. Blood. 358A-358A. 1998
- 1-800-NO-CLOTS: A quaternary care solution to a new tertiary care disease: Childhood thrombophilia. Thrombosis and Haemostasis. P2964-P2964. 1997
- A novel antithrombin-heparin covalent complex with high specific anti-factor Xa and anti-thrombin. Thrombosis and Haemostasis. P1223-P1223. 1997
- A novel antithrombin-heparin covalent complex: Efficacy and safety in rabbits. Thrombosis and Haemostasis. P2812-P2812. 1997
- Right atrial thrombosis in pediatric patients: Analysis of the Canadian registry of venous thromboembolic complications.. Pediatric Research. 907-907. 1996
- Duration of Eculizumab therapy for a clinical response in atypical hemolytic uremic syndrome.
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journal articles
- Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex.. Scientific Reports. 14:22335. 2024
- Development and validation of thromboembolism diagnostic algorithms in children with cancer from real-world data. Pediatric Research. 96:695-701. 2024
- Efanesoctocog Alfa Prophylaxis for Children with Severe Hemophilia A. New England Journal of Medicine. 391:235-246. 2024
- Pediatric pulmonary thromboembolism: a 3-year Canadian Pediatric Surveillance Program study. Journal of Thrombosis and Haemostasis. 22:1366-1371. 2024
- Considerations for instituting pediatric pulmonary embolism response teams: A tool kit. Thrombosis Research. 236:97-107. 2024
- Effects of prolonged tourniquet application on coagulation and fibrinolysis in rats. Thrombosis Update. 14:100163-100163. 2024
- Common Childhood Sleep Problems and Disorders. Current Pediatric Reviews. 20:27-42. 2024
- Nonacog beta pegol prophylaxis in children with hemophilia B: safety, efficacy, and neurodevelopmental outcomes for up to 8 years. Research and Practice in Thrombosis and Haemostasis. 8:102341-102341. 2024
- Apixaban overdose in children: case report and proposed management. A brief communication from the Pediatric and Neonatal Thrombosis and Hemostasis SSC of ISTH. Research and Practice in Thrombosis and Haemostasis. 8:102312-102312. 2024
- Effects of Prolonged Tourniquet Application on Coagulation and Fibrinolysis in Rats. Blood. 142:5411-5411. 2023
- Surgical Procedures and Hemostatic Outcome in Patients with Hemophilia Receiving Concizumab Prophylaxis during the Phase 3 explorer7 and explorer8 Trials. Blood. 142:30-30. 2023
- Scoping Review of Curricula and Pedagogical Approaches for Physiotherapist Performed Point of Care Ultrasonography. Physiotherapy Canada. Physiotherapie Canada. 75:322-336. 2023
- A diagnostic subgroup comparison of health care utilization patterns in individuals with eating disorders diagnosed in childhood and/or adolescence. International Journal of Eating Disorders. 56:1919-1930. 2023
- PB0299 Surface Modification of Lung Assist Device for Neonates by Dual-Modification with Antithrombin-Heparin (ATH) and Tissue Plasminogen Activator (t-PA). Research and Practice in Thrombosis and Haemostasis. 7:101416-101416. 2023
-
Simoctocog alfa (Nuwiq®) in previously untreated patients with severe haemophilia A—Final efficacy and safety results from the
NuProtect study. European Journal of Haematology. 111:544-552. 2023 - The multi-societal European consensus on the terminology, diagnosis and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE. British Journal of Surgery. 25:985-999. 2023
- Multisocietal European consensus on the terminology, diagnosis, and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE. British Journal of Surgery. 110:1161-1170. 2023
- Availability of Safe and Effective Therapeutic Options to Pregnant and Lactating Individuals Following the United States Food and Drug Administration Pregnancy and Lactation Labeling Rule. Journal of Pediatrics. 259:113342-113342. 2023
- International Survey of the Management of Disseminated Intravascular Coagulation Among Pediatric and Neonatal Health Care Practitioners. Journal of Pediatric Hematology/Oncology. 45:e784-e788. 2023
- The reorganisation of emergency general surgery services during the COVID-19 pandemic in the UK: outcomes of delayed presentation, socio-economic deprivation and Black, Asian and Minority Ethnic patients. Annals of the Royal College of Surgeons of England. 105:S46-S53. 2023
- Do Children With an Allergic Transfusion Reaction Require Premedication For All Blood Products?. Journal of Pediatric Hematology/Oncology. 45:e578-e581. 2023
- Long‐term immunogenicity, efficacy and tolerability of simoctocog alfa in patients with severe haemophilia A who had completed the NuProtect study in previously untreated patients. Haemophilia. 29:1005-1012. 2023
- Physiotherapist performed Point of Care Ultrasonography (POCUS): a scoping review of 209 studies. Physiotherapy. 119:34-43. 2023
- Childhood nephrotic syndrome and the clinical profile of thromboembolism: a systematic review and meta-analysis. Pediatric Research. 93:1463-1469. 2023
- Heterogeneity in the reported values and methodologies for detecting plasma D-Dimer in rat models: A systematic review. Thrombosis Update. 11:100133-100133. 2023
- Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency—first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository. Journal of Thrombosis and Haemostasis. 21:1248-1257. 2023
- Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic leukemia. Journal for ImmunoTherapy of Cancer. 11:e006649-e006649. 2023
- Recombinant factor VIII Fc fusion protein for first-time immune tolerance induction: final results of the verITI-8 study. Blood. 141:1982-1989. 2023
- BAY 81-8973 Efficacy and Safety in Previously Untreated and Minimally Treated Children with Severe Hemophilia A: The LEOPOLD Kids Trial. Thrombosis and Haemostasis. 123:027-039. 2023
- Venous thromboembolism in pediatric inflammatory bowel disease: an 11-year population-based nested case–control study in Canada. Blood Coagulation and Fibrinolysis. 33:449-456. 2022
- Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice. Scientific Reports. 12:20074. 2022
- Practical Implications of KRAS Mutation Status and Sidedness of Primary Tumour in Patients with Colorectal Cancer and Synchronous Liver Metastases: A Subset Analysis of the CoSMIC Study. Cancers. 14:4833-4833. 2022
- A retrospective cohort study examining health care utilization patterns in individuals diagnosed with an eating disorder in childhood and/or adolescence. International Journal of Eating Disorders. 55:1316-1330. 2022
- Cord-Blood High-Sensitivity Troponin-I Reference Interval and Association with Early Neonatal Outcomes. American Journal of Perinatology. 29:1548-1554. 2022
- Mixing study to diagnose heparin‐resistance caused by functional antithrombin deficiency. International Journal of Laboratory Hematology. 44:e227-e229. 2022
- Successful Use of Thrombolysis in an Extremely Low Birth Weight, Premature Infant With Aortic Thrombosis. Journal of Pediatric Hematology/Oncology. 44:e888-e891. 2022
- Risk factors for neonatal thrombosis: A retrospective study conducted in a single Canadian intensive care unit. Pediatric Blood and Cancer. 69:e29668. 2022
- Use of thrombolytic agents to treat neonatal thrombosis in clinical practice. Blood Coagulation and Fibrinolysis. 33:193-200. 2022
- Epidemiology, diagnosis and management of neonatal thrombosis: a single-center cohort study. Blood Coagulation and Fibrinolysis. 33:83-89. 2022
- Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex. Biointerphases. 17:021005. 2022
- Management of Colorectal Cancer with Synchronous Liver Metastases: An Inception Cohort Study (CoSMIC). Annals of Surgical Oncology. 29:1939-1951. 2022
- Effect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism. Journal of the American Medical Association (JAMA). 327:129-129. 2022
- Comparison of perioperative practices for placement of central venous access devices (CVAD) in children with haemophilia. The Journal of Haemophilia Practice. 9:96-102. 2022
- Development of decision-making considerations to support equitable patient selection in paediatric haemophilia trials. The Journal of Haemophilia Practice. 9:41-49. 2022
- POSC37 Economic Cost of Treatment in Canada: A Multi-Centre, Retrospective Study. Value in Health. 25:S93-S93. 2022
- Point of care ultrasonography in patients with haemophilia and acute haemarthrosis: a physiotherapist and sonographer inter-professional agreement pilot study. The Journal of Haemophilia Practice. 9:64-75. 2022
- Response to “Critical Analysis of Apixaban Dose Adjustment Criteria”. Clinical and Applied Thrombosis/Hemostasis. 28:107602962210788-107602962210788. 2022
- How to use low-molecular-weight heparin to treat neonatal thrombosis in clinical practice. Blood Coagulation and Fibrinolysis. 32:531-538. 2021
- Comparing Exercise-Induced Musculoskeletal Bleeding in Murine Models of Hemophilia A and B. Blood. 138:1031-1031. 2021
- Von Willebrand Factor Expression in Endothelium in a Co-Culturing System of Acute Lymphoblastic Leukemia. Blood. 138:4206-4206. 2021
- Simoctocog Alfa (Nuwiq) in Previously Untreated Patients with Severe Haemophilia A: Final Results of the NuProtect Study. Thrombosis and Haemostasis. 121:1400-1408. 2021
- Treatment‐induced cerebral sinus venous thrombosis in childhood acute lymphoblastic malignancies: New risk factors to consider. Pediatric Blood and Cancer. 68:e29210. 2021
- Magnetic resonance imaging in boys with severe hemophilia A: Serial and end‐of‐study findings from the Canadian Hemophilia Primary Prophylaxis Study. Research and Practice in Thrombosis and Haemostasis. 5:e12565-e12565. 2021
- Management of Anticoagulation Therapy in Patients With Thromboembolism in the Context of Renal Dysfunction: Challenging Cases and Practical Algorithms. Journal of Pediatric Hematology/Oncology. 43:e1040-e1044. 2021
- A new world of residency education: game changers and proven practices. Canadian Medical Education Journal. 12:157-246. 2021
- Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography. Blood Coagulation and Fibrinolysis. 32:305-311. 2021
- Patterns of joint damage in severe haemophilia A treated with prophylaxis. Haemophilia. 27:666-673. 2021
- Measuring the impact of hemophilia on families: Development of the Hemophilia Family Impact Tool (H‐FIT). Research and Practice in Thrombosis and Haemostasis. 5:e12519-e12519. 2021
- International pediatric thrombosis network to advance pediatric thrombosis research: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis. Journal of Thrombosis and Haemostasis. 19:1123-1129. 2021
- Central venous catheters are an important factor in paediatric thrombosis. Acta Paediatrica, International Journal of Paediatrics. 110:1001-1008. 2021
- Oral Corticosteroid Therapy as an Adjuvant Treatment for Acute Bleeding in Hemophilia Patients With High Titer Inhibitors. Journal of Pediatric Hematology/Oncology. 43:e237-e239. 2021
- Updating the Canadian Hemophilia Outcomes–Kids’ Life Assessment Tool (CHO‐KLAT) in the era of extended half‐life clotting factor concentrates. Research and Practice in Thrombosis and Haemostasis. 5:403-411. 2021
- Bone mineral density in Canadian children with severe haemophilia A or B: a cross-sectional study. The Journal of Haemophilia Practice. 8:111-118. 2021
- Dr. M. Patricia Massicotte Obituary. Journal of Thrombosis and Haemostasis. 19:313-314. 2021
- Imaging Predictors of Neurologic Outcome After Pediatric Arterial Ischemic Stroke. Stroke. 52:152-161. 2021
- Paediatrics: how to manage obstructive sleep apnoea syndrome. Drugs in Context. 10:1-14. 2021
- Paediatrics: how to manage obstructive sleep apnoea syndrome. Drugs in Context. 10. 2021
- Telemedicine in haemophilia during COVID-19 and beyond: a comprehensive review. The Journal of Haemophilia Practice. 8:98-110. 2021
- Topical nitroglycerin ointment as salvage therapy for peripheral tissue ischemia in newborns: a systematic review. CMAJ open. 9:E252-E260. 2021
- Venous thrombosis in neonates. Fac Rev. 10:20. 2021
- Web-based Application for the Population Pharmacokinetic Service (WAPPS)'s impact on dosage selection: a single paediatric centre experience. The Journal of Haemophilia Practice. 8:80-85. 2021
- Heparin-Induced Thrombocytopenia in a Pediatric Population: Implications for Clinical Probability Scores and Testing. Journal of Pediatrics. 226:167-172.e2. 2020
- Safety and efficacy of anticoagulant therapy in pediatric catheter-related venous thrombosis (EINSTEIN-Jr CVC-VTE). Blood Advances. 4:4632-4639. 2020
- Cancer and Tumor-Associated Childhood Stroke: Results From the International Pediatric Stroke Study. Pediatric Neurology. 111:59-65. 2020
- Nonacog beta pegol (N9‐GP) in hemophilia B: First report on safety and efficacy in previously untreated and minimally treated patients. Research and Practice in Thrombosis and Haemostasis. 4:1101-1113. 2020
- High adherence to prophylaxis regimens in haemophilia B patients receiving rIX‐FP: Evidence from clinical trials and real‐world practice. Haemophilia. 26:637-642. 2020
- Incidence, Risk Factors, and Outcomes of Neonatal Renal Vein Thrombosis in Ontario: Population-Based Cohort Study. Kidney360. 1:640-647. 2020
- Miniaturization of Artificial Lungs toward Portability. Advanced Materials Technologies. 5:2000136-2000136. 2020
- Pediatric drug data in Canadian drug monographs: a descriptive analysis. CMAJ open. 8:E522-E529. 2020
- Rivaroxaban for treatment of pediatric venous thromboembolism. An Einstein‐Jr phase 3 dose‐exposure‐response evaluation. Journal of Thrombosis and Haemostasis. 18:1672-1685. 2020
- The Edoxaban Hokusai VTE PEDIATRICS Study: An open‐label, multicenter, randomized study of edoxaban for pediatric venous thromboembolic disease. Research and Practice in Thrombosis and Haemostasis. 4:886-892. 2020
- Inferior vena cava syndrome in neonates: An evidence‐based systematic review of the literature. Pediatric Blood and Cancer. 67:e28114. 2020
- GOSAFE - Geriatric Oncology Surgical Assessment and Functional rEcovery after Surgery: early analysis on 977 patients. Journal of Geriatric Oncology. 11:244-255. 2020
- Hemophilia prophylaxis adherence and bleeding using a tailored, frequency‐escalated approach: The Canadian Hemophilia Primary Prophylaxis Study. Research and Practice in Thrombosis and Haemostasis. 4:318-325. 2020
- MOLECULAR MECHANISMS OF INHIBITOR DEVELOPMENT IN HEMOPHILIA. Mediterranean Journal of Hematology and Infectious Diseases. 12:e2020001-e2020001. 2020
- Potential Risk Factors Contributing to Development of Venous Thromboembolism for Total Knee Replacements Patients Prophylaxed With Rivaroxaban: A Retrospective Case-Control Study. Clinical and Applied Thrombosis/Hemostasis. 26:107602962096222-107602962096222. 2020
- Predictors of treatment adherence in patients with chronic disease using the Multidimensional Adherence Model: unique considerations for patients with haemophilia. The Journal of Haemophilia Practice. 7:92-101. 2020
- Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial. The Lancet Haematology. 7:e18-e27. 2020
- Age-Dependent Variation in Glycosylation Features of Alpha-2-Macroglobulin. Cell Biochemistry and Biophysics. 77:335-342. 2019
- Results of a multinational survey of diagnostic and management practices of thromboembolic pulmonary embolism in children. Thrombosis Research. 183:98-105. 2019
- P76 The effect of the pregnancy and lactation labeling rule on prescribing information of FDA-approved drugs. Archives of Disease in Childhood. 104:e48.2-e48. 2019
- P77 Pediatric drug data in Canadian drug monographs. Archives of Disease in Childhood. 104:e49.1-e49. 2019
- Characterization of Post-Thrombotic Syndrome in Children with Cardiac Disease. Journal of Pediatrics. 207:42-48. 2019
- Outcomes following neonatal portal vein thrombosis: A descriptive, single‐center study and review of anticoagulant therapy. Pediatric Blood and Cancer. 66:e27572. 2019
- Feasibility and safety of delivering full‐dose anticoagulation therapy in children treated according to Dana‐Farber Cancer Institute acute lymphoblastic leukemia consortium therapy protocols. Pediatric Blood and Cancer. 66:e27483. 2019
- Barriers to the implementation of point-of-care ultrasonography by physiotherapists in haemophilia treatment centres in Canada: a modified Delphi approach. The Journal of Haemophilia Practice. 6:29-41. 2019
- A Practical Guide to the Management of the Fetus and Newborn With Hemophilia. Clinical and Applied Thrombosis/Hemostasis. 24:29S-41S. 2018
- Clinical presentation and therapeutic management of venous thrombosis in young children: a retrospective analysis. Thrombosis Journal. 16:29. 2018
- Exploratory evaluation of pharmacodynamics, pharmacokinetics and safety of rivaroxaban in children and adolescents: an EINSTEIN-Jr phase I study. Thrombosis Journal. 16:31. 2018
- Rivaroxaban versus standard anticoagulation for acute venous thromboembolism in childhood. Design of the EINSTEIN-Jr phase III study. Thrombosis Journal. 16:34. 2018
- American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism. Blood Advances. 2:3292-3316. 2018
- Relation between HbA1c and incident cardiovascular disease over a period of 6 years in the Hong Kong population. Diabetes and Metabolism. 44:415-423. 2018
- Pediatric superior vena cava syndrome: An evidence‐based systematic review of the literature. Pediatric Blood and Cancer. 65:e27225. 2018
- Rivaroxaban and dabigatran did not affect clotting profiles in plasma reconstituted with varying levels of autologous platelets to the same degree as heparin when evaluated using thromboelastography. Blood Coagulation and Fibrinolysis. 29:521-527. 2018
- Conservative management of neonatal cerebral sinovenous thrombosis with coexisting thrombophilia. Blood Coagulation and Fibrinolysis. 29:399-403. 2018
- Tailored frequency-escalated primary prophylaxis for severe haemophilia A: results of the 16-year Canadian Hemophilia Prophylaxis Study longitudinal cohort. The Lancet Haematology. 5:e252-e260. 2018
- RESEARCH COLLABORATION WITHIN A DEPARTMENT OF PEDIATRICS: A SOCIAL NETWORK ANALYSIS OF COAUTHORSHIP PATTERNS. Paediatrics and Child Health. 23:e58-e58. 2018
- Impact of baseline clinical and laboratory features on the risk of thrombosis in children with acute lymphoblastic leukemia: A prospective evaluation. Pediatric Blood and Cancer. 65:e26938. 2018
- Mortality After Pediatric Arterial Ischemic Stroke. Pediatrics. 141:e20174146. 2018
- Point‐of‐care ultrasonography in haemophilia care: Training and competency for muscular haematomas. Haemophilia. 24:335-337. 2018
- Incidence and Management of Thrombotic and Thromboembolic Complications Following the Superior Cavopulmonary Anastomosis Procedure: A Literature Review. Clinical and Applied Thrombosis/Hemostasis. 24:405-415. 2018
- Successful conservative management of a superficial pediatric pseudoaneurysm. Journal of Pediatric Surgery Case Reports. 31:64-68. 2018
- A brief survey of clinicians’ perceptions of parent preferences for involvement in obstetrical and perinatal management decisions in haemophilia. Haemophilia. 24:e80-e83. 2018
-
Immunogenicity, efficacy and safety of Nuwiq® (human‐cl rh
FVIII ) in previously untreated patients with severe haemophilia A—Interim results from the NuProtect Study. Haemophilia. 24:211-220. 2018 - Recommendations for future research in relation to pediatric pulmonary embolism: communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis. 16:405-408. 2018
- Abstract 15: Mortality After Pediatric Arterial Ischemic Stroke: Results From the International Paediatric Stroke Study. Stroke. 49. 2018
- Dyslipidemia in Children With Arterial Ischemic Stroke: Prevalence and Risk Factors. Pediatric Neurology. 78:46-54. 2018
- RESEARCH COLLABORATION WITHIN A DEPARTMENT OF PEDIATRICS: A SOCIAL NETWORK ANALYSIS OF COAUTHORSHIP PATTERNS. Paediatrics and Child Health. 23:e58-e58. 2018
- The identification of at‐risk patients and prevention of venous thromboembolism in pediatric cancer: guidance from the SSC of the ISTH. Journal of Thrombosis and Haemostasis. 16:175-180. 2018
- Cerebral sinus venous thrombosis during childhood acute lymphoblastic leukemia therapy: Risk factors and management. Pediatric Blood and Cancer. 64. 2017
- Evaluation for inherited and acquired prothrombotic defects predisposing to symptomatic thromboembolism in children with acute lymphoblastic leukemia: a protocol for a prospective, observational, cohort study. BMC Cancer. 17:313. 2017
- Incidence and Management of Thrombotic and Thromboembolic Complications Following the Norwood Procedure: A Systematic Review. Clinical and Applied Thrombosis/Hemostasis. 23:911-921. 2017
- Recommendations for standardized risk factor definitions in pediatric hospital‐acquired venous thromboembolism to inform future prevention trials: communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis. 15:2274-2278. 2017
- In-vitro assessment of the effect of dabigatran on thrombosis of adult and neonatal plasma. Blood Coagulation and Fibrinolysis. 28:551-557. 2017
- Anticoagulation therapy in neonates, children and adolescents. Blood Cells, Molecules, and Diseases. 67:41-47. 2017
- Inhibition of plasmin generation in plasma by heparin, low molecular weight heparin, and a covalent antithrombin–heparin complex. Blood Coagulation and Fibrinolysis. 28:431-437. 2017
- Point of care ultrasound in haemophilia: Building a strong foundation for clinical implementation. Haemophilia. 23:648-651. 2017
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Molecular structural analysis of a novel and de‐novo mutation in the
SERPINC 1 gene associated with type 1 antithrombin deficiency. British Journal of Haematology. 177:654-656. 2017 - Epidemiology and Outcomes of Arterial Ischemic Stroke in Children: The Canadian Pediatric Ischemic Stroke Registry. Pediatric Neurology. 69:58-70. 2017
- Myocardial Infarction in Neonates: A Review of an Entity with Significant Morbidity and Mortality. Pediatric Cardiology. 38:427-441. 2017
- The association of platelets with failed patent ductus arteriosus closure after a primary course of indomethacin or ibuprofen: a systematic review and meta-analysis. Journal of Maternal-Fetal and Neonatal Medicine. 30:127-133. 2017
- Effect of a structured diabetes education programme in primary care on hospitalizations and emergency department visits among people with Type 2 diabetes mellitus: results from the Patient Empowerment Programme. Diabetic Medicine. 33:1427-1436. 2016
- How to use unfractionated heparin to treat neonatal thrombosis in clinical practice. Blood Coagulation and Fibrinolysis. 27:605-614. 2016
- Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke. Stroke. 47:2221-2228. 2016
- To anticoagulate? Controversy in the management of thrombotic complications of head & neck infections. International Journal of Pediatric Otorhinolaryngology. 88:129-135. 2016
- Transfusion premedication practices among pediatric health care practitioners in Canada: results of a national survey. Transfusion. 56:2296-2302. 2016
- Neonatal central venous catheter thrombosis: diagnosis, management, and outcome.. Blood Coagulation and Fibrinolysis. 2016
- Patent foramen ovale and stroke in childhood: A systematic review of the literature. European Journal of Paediatric Neurology. 20:500-511. 2016
- Risk factors for central venous catheter-related thrombosis in children. Blood Coagulation and Fibrinolysis. 27:384-388. 2016
- Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis?. Stroke. 47:1265-1270. 2016
- The Management of Colorectal Cancer with Synchronous liver-limited Metastatic Disease: An Audit of Current Practice Against European Society of Medical Oncology (ESMO) Guidelines.. HPB. 18:e832-e832. 2016
- Tumour biological profiles of primary colorectal cancers and liver metastases: An overview to identify keys to the metastatic phenomenon. HPB. 18:e189-e189. 2016
- Using the metabolic phenotype of pancreatic ductal adenocarcinoma (PDAC) to identify potential targetable cancer-specific pathways. HPB. 18:e360-e361. 2016
- Central venous access device insertion and perioperative management of patients with severe haemophilia A. Blood Coagulation and Fibrinolysis. 27:156-159. 2016
- Challenges with heparin-based anticoagulation during cardiopulmonary bypass in children: Impact of low antithrombin activity. Journal of Thoracic and Cardiovascular Surgery. 151:444-450. 2016
- First prospective report on immune tolerance in poor risk haemophilia A inhibitor patients with a single factor VIII/von Willebrand factor concentrate in an observational immune tolerance induction study. Haemophilia. 22:87-95. 2016
- Long-acting recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in children. Thrombosis and Haemostasis. 116:659-668. 2016
- Risk of Recurrent Arterial Ischemic Stroke in Childhood. Stroke. 47:53-59. 2016
- Abstract 18025: Systematic Screening is Necessary to Detect Post-operative Thrombosis and Evaluate Risk in Children Undergoing Cardiac Surgery: A Prospective Observational Study. Circulation. 132. 2015
- Abstract 18061: Supplementation to Treat Antithrombin Deficiency Improves Sensitivity to Heparin, Anticoagulation and Decreased Thrombogenecity in Neonates and Infants Undergoing Cardiac Surgery With Cardiopulmonary Bypass. Circulation. 132. 2015
- Point of care ultrasonography in haemophilia care: recommendations for training and competency evaluation. Haemophilia. 21:828-831. 2015
- Feasibility and safety of enoxaparin whole milligram dosing in premature and term neonates. Journal of Perinatology. 35:852-854. 2015
- INFLAMMATORY AND HEMOSTATIC RESPONSE TO CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS IN CHILDREN: IMPACT OF INTRAOPERATIVE MANAGEMENT. Canadian Journal of Cardiology. 31:S307-S307. 2015
- Heterogeneity of information regarding inhibitors in the product monographs of antihaemophilic factors in North America. Haemophilia. 21:e448-e451. 2015
- Surface modification of poly(dimethylsiloxane) with a covalent antithrombin–heparin complex for the prevention of thrombosis: use of polydopamine as bonding agent. Journal of Materials Chemistry B. 3:6032-6036. 2015
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Experience with central venous access devices (
CVAD s) in the Canadian hemophilia primary prophylaxis study (CHPS ). Haemophilia. 21:469-476. 2015 - c.1058C>T variant in the SERPINC1 gene is pathogenic for antithrombin deficiency. British Journal of Haematology. 170:123-125. 2015
- Sedentary Time and Screen-Based Sedentary Behaviors of Children With a Chronic Disease. Pediatric Exercise Science. 27:219-225. 2015
- Improving cross-modal face recognition using polarimetric imaging. Optics Letters. 40:882-882. 2015
- Recommendations for the assessment of non‐extremity venous thromboembolism outcomes: communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis. 13:477-480. 2015
- Recommendations for the development of new anticoagulant drugs for pediatric use: communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis. 13:481-484. 2015
- Thrombolysis in Pediatric Stroke Study. Stroke. 46:880-885. 2015
- Treatment decision‐making among Canadian youth with severe haemophilia: a qualitative approach. Haemophilia. 21:180-189. 2015
- Paediatric cerebral sinovenous thrombosis: findings of the International Paediatric Stroke Study. Archives of Disease in Childhood. 100:174-179. 2015
- Patient Empowerment Programme in primary care reduced all‐cause mortality and cardiovascular diseases in patients with type 2 diabetes mellitus: a population‐based propensity‐matched cohort study. Diabetes, Obesity and Metabolism. 17:128-135. 2015
- Pharmacokinetics of recombinant and plasma-derived factor IX products in pediatric patients with severe hemophilia B. Blood Coagulation and Fibrinolysis. 26:113-114. 2015
- Stroke in Children With Cardiac Disease: Report From the International Pediatric Stroke Study Group Symposium. Pediatric Neurology. 52:5-15. 2015
- Inhibition of Plasmin Generation in Plasma By Heparin, Low Molecular Weight Heparin and a Covalent Antithrombin-Heparin Complex (ATH). Blood. 124:4217-4217. 2014
- The Effect of Age on the Glycosylation of Human Alpha-2-Macroglobulin. Blood. 124:2800-2800. 2014
- The Effects of Thrombocytopenia on Clotting Profile in Whole Blood As Determined By Thromboelastography When Anticoagulant Is Present at Therapeutic or Prophylactic Concentration. Blood. 124:1550-1550. 2014
- Arteriopathy Diagnosis in Childhood Arterial Ischemic Stroke. Stroke. 45:3597-3605. 2014
- Corrigendum. Journal of Thrombosis and Haemostasis. 12:1948-1948. 2014
- COAGULATION SYSTEM ABNORMALITIES AND HEPARIN RESPONSE IN CHILDREN UNDERGOING CARDIAC SURGERY. Canadian Journal of Cardiology. 30:S171-S172. 2014
- PO-0759 Surface Modification Of A Polydimethylsiloxane Microfluidic Oxygenator With Dopamine And A Covalent Antithrombin-heparin Complex For The Prevention Of Thrombosis. Archives of Disease in Childhood. 99:A503.2-A504. 2014
- Protamine Requirements in Cardiac Surgery: Effect of Changes in the Heparin Reference Standard. Journal of Cardiothoracic and Vascular Anesthesia. 28:1227-1232. 2014
- Challenges and Priorities for Research. Circulation. 130:1192-1203. 2014
- Thrombotic Complications of Neonates and Children with Congenital Nephrotic Syndrome. Current Pediatric Reviews. 10:169-176. 2014
- Clinical presentation and molecular basis of congenital antithrombin deficiency in children: a cohort study. British Journal of Haematology. 166:130-139. 2014
- Emergence of the Primary Pediatric Stroke Center. Stroke. 45:2018-2023. 2014
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First analysis of 10‐year trends in national factor concentrates usage in haemophilia: data from
CHARMS , the Canadian Hemophilia Assessment and Resource Management System. Haemophilia. 20:e251-e259. 2014 - Thrombosis and Thromboembolic Complications in Fontan Patients. Clinical and Applied Thrombosis/Hemostasis. 20:484-492. 2014
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Evaluation of an automated method for measuring von
W illebrand factor activity in clinical samples without ristocetin. International Journal of Laboratory Hematology. 36:341-351. 2014 - Phenotype Presentation for a Novel Mutation Affecting a Conserved Cysteine Residue in Exon 63 of Fibrillin-1 (Cys2633Arg). Biochemical Genetics. 52:225-232. 2014
- Surface modification of polydimethylsiloxane with a covalent antithrombin–heparin complex to prevent thrombosis. Journal of Biomaterials Science, Polymer Edition. 25:786-801. 2014
- Reversal of New, Factor-specific Oral Anticoagulants by rFVIIa, Prothrombin Complex Concentrate and Activated Prothrombin Complex Concentrate: A Review of Animal and Human Studies. Thrombosis Research. 133:705-713. 2014
- Factor XIII deficiency management. Blood Coagulation and Fibrinolysis. 25:199-205. 2014
- Supportive Care in Pediatric Cancer: The Road to Prevention of Thrombosis. Seminars in Vascular Medicine. 40:371-381. 2014
- Consensus Statements on the Risk, Prevention, and Treatment of Venous Thromboembolism in Inflammatory Bowel Disease: Canadian Association of Gastroenterology. Gastroenterology. 146:835-848.e6. 2014
- Neonatal central venous catheter thrombosis. Blood Coagulation and Fibrinolysis. 25:97-106. 2014
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What should men living with haemophilia need to know? The perspectives of
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- Pediatric Thrombophilia. Pediatric Clinics of North America. 60:1443-1462. 2013
- Spontaneous neonatal arterial thromboembolism. Blood Coagulation and Fibrinolysis. 24:787-797. 2013
- Reversal Of Dabigatran By Recombinant Factor VIIa Is Dependent On The Amount Of Tissue-Factor. Blood. 122:1149-1149. 2013
- The Architecture Of Fibrin Clots Formed From Plasma With Low Platelet Levels Are Less Altered In The Presence Of Factor-Specific Anticoagulants Compared With Unfractionated Heparin. Blood. 122:578-578. 2013
- Tranexamic Acid is a Weak Provoking Factor For Thromboembolic Events: A Systematic Review Of The Literature. Blood. 122:3629-3629. 2013
- Evaluation of the Use of Low-Molecular-Weight Heparin in Neonates. Clinical and Applied Thrombosis/Hemostasis. 19:488-493. 2013
- How I manage heavy menstrual bleeding. British Journal of Haematology. 162:721-729. 2013
- What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers. Haemophilia. 19:503-510. 2013
- Artificial Placenta - Lung Assist Devices for Term and Preterm Newborns with Respiratory Failure. International Journal of Artificial Organs. 36:377-391. 2013
- Neonatal and childhood right atrial thrombosis. Blood Coagulation and Fibrinolysis. 24:458-458. 2013
- Current Guidelines and Strategies in Management of Renal Vein Thrombosis. Current Pediatric Reviews. 9:240-249. 2013
- Thrombotic Thrombocytopenic Purpura, from the Perspectives of a Pediatrician. Current Pediatric Reviews. 9:205-217. 2013
- Thrombosis and embolism in pediatric cardiomyopathy. Blood Coagulation and Fibrinolysis. 24:221-230. 2013
- Glycolytic regulation of the plasma membrane Ca2+ atpase in pancreatic ductal adenocarcinoma. Pancreatology. 13:e36-e36. 2013
- Musculoskeletal health of subjects with hemophilia A treated with tailored prophylaxis: Canadian Hemophilia Primary Prophylaxis (CHPS) Study. Journal of Thrombosis and Haemostasis. 11:460-466. 2013
- Comparison of N-linked glycosylation of protein C in newborns and adults. Carbohydrate Research. 365:32-37. 2013
- Covalently linking heparin to antithrombin enhances prothrombinase inhibition on activated platelets. Thrombosis and Haemostasis. 109:1016-1024. 2013
- Diagnosis and treatment of intracranial hemorrhage in children with hemophilia. Blood Coagulation and Fibrinolysis. 24:23-27. 2013
- Diagnosis and treatment of intracranial hemorrhage in children with hemophilia. Blood Coagulation and Fibrinolysis. 24:23-27. 2013
- Inhibition of the prothrombinase complex on red blood cells by heparin and covalent antithrombin-heparin complex. Journal of Biochemistry. 153:103-110. 2013
- Interactions of heparin and a covalently-linked antithrombin-heparin complex with components of the fibrinolytic system. Thrombosis and Haemostasis. 110:1180-1188. 2013
- The Coagulation System in Humans. Methods in molecular biology (Clifton, N.J.). 992:3-12. 2013
- The Role of the Vessel Wall. Methods in molecular biology (Clifton, N.J.). 992:31-46. 2013
- Thrombin Generation. Methods in molecular biology (Clifton, N.J.). 992:139-154. 2013
- Updates in thrombosis in pediatrics: where are we after 20 years?. Hematology. American Society of Hematology. Education Program. 2012:439-443. 2012
- Do children with central venous line (CVL) dysfunction have increased risk of symptomatic thromboembolism compared to those without CVL-dysfunction, while on cancer therapy?. BMC Cancer. 12:314. 2012
- Ten-Year Canadian National Prospective Data On Utilization of Anti-Hemophilic Concentrates: Indications and Trends. Blood. 120:1186-1186. 2012
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A
C anadian survey of self‐infusion practices in persons with haemophilia A. Haemophilia. 18:e403-e405. 2012 - Thrombotic thrombocytopenic purpura in pediatric patients.. Chinese Journal of Contemporary Pediatrics. 14:803-810. 2012
- Neonatal and infant pulmonary thromboembolism. Blood Coagulation and Fibrinolysis. 23:653-662. 2012
- Polyurethane modified with an antithrombin‐heparin complex via polyethylene oxide linker/spacers: Influence of PEO molecular weight and PEO‐ATH bond on catalytic and direct anticoagulant functions. Journal of Biomedical Materials Research - Part A. 100A:2821-2828. 2012
- Standardization of post‐thrombotic syndrome definition and outcome assessment following upper venous system thrombosis in pediatric practice. Journal of Thrombosis and Haemostasis. 10:2182-2185. 2012
- The importance of haemophilia treatment centre administrators in patient care. Haemophilia. 18:e366-e367. 2012
- Thrombotic Complications and Thromboprophylaxis Across All Three Stages of Single Ventricle Heart Palliation. Journal of Pediatrics. 161:513-519.e3. 2012
- Body mass index and thromboembolism in children with hematological malignancies. Pediatric Blood and Cancer. 59:320-322. 2012
- Mechanism of inhibition of the prothrombinase complex by a covalent antithrombin-heparin complex. Journal of Biochemistry. 152:139-148. 2012
- Erratum. American Journal of Hematology. 87:748-748. 2012
- Management of children after renal transplantation: highlights for general pediatricians.. Translational Pediatrics. 1:35-46. 2012
- A surfacing problem. Ibnosina Journal of Medicine and Biomedical Sciences. 04:103-105. 2012
- Determination of alpha-2-macroglobulin complexes by a new immuno-activity assay. Thrombosis Research. 129:635-640. 2012
- Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors. American Journal of Hematology. 87:S141-S145. 2012
- Longer Blood Storage Is Associated With Suboptimal Outcomes in High-Risk Pediatric Cardiac Surgery. Annals of Thoracic Surgery. 93:1563-1569. 2012
- Central Venous Line Dysfunction is an Independent Predictor of Poor Survival in Children With Cancer. Journal of Pediatric Hematology/Oncology. 34:188-193. 2012
- Definition of post‐thrombotic syndrome following lower extremity deep venous thrombosis and standardization of outcome measurement in pediatric clinical investigations. Journal of Thrombosis and Haemostasis. 10:477-480. 2012
- Heparin Brand Is Associated With Postsurgical Outcomes in Children Undergoing Cardiac Surgery. Annals of Thoracic Surgery. 93:878-882. 2012
- Unfractionated heparin dosing in young infants: clinical outcomes in a cohort monitored with anti‐factor Xa levels. Journal of Thrombosis and Haemostasis. 10:368-374. 2012
- Antithrombotic Therapy in Neonates and Children. Chest. 141:e737S-e801S. 2012
- [Management of children after renal transplantation: highlights for general pediatricians].. Chinese Journal of Contemporary Pediatrics. 14:81-88. 2012
- Modification of Polyurethane Surface with an Antithrombin–Heparin Complex for Blood Contact: Influence of Molecular Weight of Polyethylene Oxide Used as a Linker/Spacer. Langmuir. 28:2099-2106. 2012
- Safety of anticoagulants in children with arterial ischemic stroke. Blood. 119:949-956. 2012
- Recommendations for developing uniform laboratory monitoring of heparinoid anticoagulants in children. Journal of Thrombosis and Haemostasis. 10:145-147. 2012
- Diagnosis and management of neonatal purpura fulminans. Seminars in Fetal and Neonatal Medicine. 16:318-322. 2011
- Neonatal portal vein thrombosis: Diagnosis and management. Seminars in Fetal and Neonatal Medicine. 16:329-339. 2011
- Co-Administration Therapy Modulates Immunity to FVIII In Hemophilia A Mice. Blood. 118:1219-1219. 2011
- Exploring the Impact of Clinical Anticoagulants on Venous Thrombosis Stability Using a Novel Intravital Murine Model. Blood. 118:1246-1246. 2011
- Inhibition of Red Blood Cell-Prothrombinase by Heparin and a Covalent Antithrombin-Heparin Complex. Blood. 118:1179-1179. 2011
- Comparing bleed frequency and factor concentrate use between haemophilia A and B patients. Haemophilia. 17:872-874. 2011
- Thrombosis in Children with Acute Lymphoblastic Leukemia Treated at a Tertiary Care Center in Lebanon: Revisiting the Role of Predictive Models. International Journal of Pediatric Hematology/Oncology. 28:676-681. 2011
- Risk, Clinical Features, and Outcomes of Thrombosis Associated With Pediatric Cardiac Surgery. Circulation. 124:1511-1519. 2011
- Carotid artery dissections: Thrombosis of the false lumen. Thrombosis Research. 128:317-324. 2011
- Impact of Persistent Antiphospholipid Antibodies on Risk of Incident Symptomatic Thromboembolism in Children: A Systematic Review and Meta-Analysis. Seminars in Vascular Medicine. 37:802-809. 2011
- Thrombosis in Children. Seminars in Vascular Medicine. 37:763-761. 2011
- Clotting factor concentrates given to prevent bleeding and bleeding-related complications in people with hemophilia A or B. Clinical Respiratory Journal. 9:CD003429. 2011
- 414 Thrombus persistence and embolization after pediatric cardiac surgery. Canadian Journal of Cardiology. 27:S211-S212. 2011
- 415 Definition, characterization and clinical sequelae of post-thrombotic syndrome in chidlren with congenital heart disease. Canadian Journal of Cardiology. 27:S212-S212. 2011
- Adherence with haemophilia treatments: a survey of haemophilia healthcare professionals in Canada. Haemophilia. 17:816-817. 2011
- Inherited Thrombophilia in Childhood Arterial Stroke: Data from Lebanon. Pediatric Neurology. 45:155-158. 2011
- Immobilization of an antithrombin–heparin complex on gold: Anticoagulant properties and platelet interactions. Acta Biomaterialia. 7:2029-2034. 2011
- Binding of Heparin to Metals. Cell Biochemistry and Biophysics. 59:171-178. 2011
- Immune tolerance induction for a patient with factor IX inhibitors - a case report. Haemophilia. 17:315-315. 2011
- Chemical–Physical Characterization of Polyurethane Catheters Modified with a Novel Antithrombin-Heparin Covalent Complex. Journal of Biomaterials Science, Polymer Edition. 22:2277-2294. 2011
- Need for a new paediatric post thrombotic sequelae outcome measure for non-extremity thrombosis. Thrombosis and Haemostasis. 105:1105-1106. 2011
- Antithrombin-heparin covalent complex reduces microemboli during cardiopulmonary bypass in a pig model. Blood. 116:5716-5723. 2010
- Neonatal Systemic Venous Thrombosis. Thrombosis Research. 126:471-476. 2010
- Impact of Persistent Antiphospholipid Antibodies on Symptomatic Thromboembolism In Children: A Systematic Review & Meta-Analysis [Observational Studies]. Blood. 116:3169-3169. 2010
- Randomized, Controlled Trial of Individualized Heparin and Protamine Management in Infants Undergoing Cardiac Surgery With Cardiopulmonary Bypass. Journal of the American College of Cardiology. 56:1794-1802. 2010
- Management of myocardial infarction in children with Kawasaki disease. Blood Coagulation and Fibrinolysis. 21:620-631. 2010
- Coagulopathy in a patient with nephrotic syndrome. American Journal of Hematology. 85:708-710. 2010
- Neonatal Cerebral Sinovenous Thrombosis: Sifting the Evidence for a Diagnostic Plan and Treatment Strategy. Pediatrics. 126:e693-e700. 2010
- Effect of covalent antithrombin-heparin on activated protein C inactivation by protein C inhibitor. Journal of Biochemistry. 148:255-260. 2010
- Surface modification with an antithrombin–heparin complex for anticoagulation: Studies on a model surface with gold as substrate. Acta Biomaterialia. 6:2911-2919. 2010
- Bleeding disorders in neonates. Haemophilia. 16:168-175. 2010
- Von Willebrand factor and thrombin activation in children with newly diagnosed acute lymphoblastic leukemia: An impact of peripheral blasts. Pediatric Blood and Cancer. 54:963-969. 2010
- Neonatal and childhood right atrial thrombosis: recognition and a risk-stratified treatment approach. Blood Coagulation and Fibrinolysis. 21:301-307. 2010
- Anticoagulants in pediatric cerebral sinovenous thrombosis: A safety and outcome study. Annals of Neurology. 67:590-599. 2010
- Neonatal Aortic Thrombosis: A Comprehensive Review. Klinische Padiatrie. 222:134-139. 2010
- Impact of Thrombophilia on Risk of Arterial Ischemic Stroke or Cerebral Sinovenous Thrombosis in Neonates and Children. Circulation. 121:1838-1847. 2010
- Management and Monitoring of Anticoagulation for Children Undergoing Cardiopulmonary Bypass in Cardiac Surgery. Journal of Extra-Corporeal Technology. 42:9-19. 2010
- Novel paediatric anticoagulants: a review of the current literature. Blood Coagulation and Fibrinolysis. 21:144-151. 2010
- Anti-prothrombin antibodies and other acquired antibodies associated with thrombosis in children. Thrombosis Research. 125:2-3. 2010
- Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va. Thrombosis and Haemostasis. 103:910-919. 2010
- Varied opinions on thrombolysis for venous thromboembolism in infants and children: Findings from a survey of pediatric hematology–oncology specialists. Pediatric Blood and Cancer. 53:960-966. 2009
- Covalent Antithrombin-Heparin Complex Catalysis of Activated Protein C Inhibition by Protein C Inhibitor.. Blood. 114:3167-3167. 2009
- Distribution and Clinical Signs of Venous, Arterial and Intracardiac Clots After Pediatric Cardiac Surgery.. Blood. 114:3992-3992. 2009
- Impact of Thrombophilia On Arterial Ischemic Stroke or Cerebral Venous Sinus Thromboses in Children: A Systematic Review & Meta-Analysis of Observational Studies.. Blood. 114:3993-3993. 2009
- Investigation Into Mechanisms of Prothrombinase Complex Inhibition by a Covalent Antithrombin-Heparin Complex.. Blood. 114:2136-2136. 2009
- Undetected factor VIII in a patient with type 3 von Willebrands disease mistaken as severe haemophilia A. Haemophilia. 15:1258-1261. 2009
- Clinical probability score and D‐dimer estimation lack utility in the diagnosis of childhood pulmonary embolism. Journal of Thrombosis and Haemostasis. 7:1633-1638. 2009
- No Association Between Protein C Levels and Bacteremia in Children With Febrile Neutropenia. Journal of Pediatric Hematology/Oncology. 31:647-650. 2009
- Renal venous thrombosis in a newborn with prothrombotic risk factors. Blood Coagulation and Fibrinolysis. 20:458-460. 2009
- The use of elastic compression stockings for post‐thrombotic syndrome in a child. Pediatric Blood and Cancer. 53:462-463. 2009
- Intravascular Targeting of a New Anticoagulant Heparin Compound. Cardiovascular and Hematological Disorders - Drug Targets. 9:149-158. 2009
- Use of alteplase in childhood arterial ischaemic stroke: a multicentre, observational, cohort study. Lancet Neurology. 8:530-536. 2009
- Effect of covalent antithrombin-heparin complex on developmental mechanisms in the lung. American Journal of Physiology - Lung Cellular and Molecular Physiology. 296:L394-L403. 2009
- Anticoagulant mechanisms of covalent antithrombin-heparin investigated by thrombelastography. Thrombosis and Haemostasis. 102:62-68. 2009
- Antithrombotic therapy in children with venous thromboembolism. Hamostaseologie. 29:80-87. 2009
- Comparison of recombinant and plasma-derived antithrombin biodistribution in a rabbit model. Thrombosis and Haemostasis. 102:302-308. 2009
- Thrombolysis in Acute Childhood Stroke: Design and Challenges of the Thrombolysis in Pediatric Stroke Clinical Trial. Neuroepidemiology. 32:279-286. 2009
- Epidemiology and clinical risk factors predisposing to thromboembolism in children with cancer. Pediatric Blood and Cancer. 51:792-797. 2008
- Frequency, Predictors, and Neurologic Outcomes of Vaso-occlusive Strokes Associated With Cardiac Surgery in Children. Pediatrics. 122:1292-1298. 2008
- Age-Related Differences in the Glycosylation of Anticoagulant Protein C.. Blood. 112:2031-2031. 2008
- Circulating Blasts Are Associated with High Levels of vWF and Thrombin Activation in Children with Newly Diagnosed ALL.. Blood. 112:1824-1824. 2008
- Use of Factor VIII/Von Willebrand Factor Complex for Inducing Immune Tolerance in Hemophilia a Patients Who Have Failed with Recombinant Fviii: Recent Canadian Experience. Blood. 112:4520-4520. 2008
- Abstract 2598: Individualized Heparin and Protamine Management Protocol in Infants Undergoing Cardiopulmonary Bypass for Cardiac Surgery Improves Immediate Post-operative Clinical Outcomes. Circulation. 118. 2008
- Impact of Inherited Thrombophilia on Venous Thromboembolism in Children. Circulation. 118:1373-1382. 2008
- Clinical features and outcome of pulmonary embolism in children. British Journal of Haematology. 142:808-818. 2008
- Practical Model-Based Dose Finding in Early-Phase Clinical Trials. Stroke. 39:2627-2636. 2008
- The use of prophylaxis in 2663 children and adults with haemophilia: results of the 2006 Canadian national haemophilia prophylaxis survey. Haemophilia. 14:923-930. 2008
- Arterial Ischemic Stroke: Experience in Chinese Children. Pediatric Neurology. 39:142-143. 2008
- Antithrombotic Therapy in Neonates and Children. Chest. 133:887S-968S. 2008
- Review on Patents for Potent Anticoagulant Antithrombin-Heparin Covalent Complexes that Control Thrombosis In Vivo. Recent Patents on Biomedical Engineering. 1:82-91. 2008
- Arterial thrombosis in children. Expert Review of Cardiovascular Therapy. 6:419-428. 2008
- Venous thrombosis in children. Expert Review of Cardiovascular Therapy. 6:411-418. 2008
- A systematic review and survey of the management of unexpected neonatal alloimmune thrombocytopenia. Transfusion. 48:92-98. 2008
- An Antithrombin-Heparin Complex Increases the Anticoagulant Activity of Fibrin Clots. Biochemistry Research International. 2008:1-4. 2008
- Enoxaparin for neonatal thrombosis: A call for a higher dose for neonates. Thrombosis Research. 122:826-830. 2008
- Thromboembolism in Infants and Children With Gastrointestinal Failure Receiving Long‐Term Parenteral Nutrition. Journal of Parenteral and Enteral Nutrition. 32:88-93. 2008
- Thromboembolism in children with lymphoma. Thrombosis Research. 122:459-465. 2008
- Treatment of endothelium with the chemotherapy agent vincristine affects activated protein C generation to a greater degree in newborn plasma than in adult plasma. Thrombosis Research. 122:418-426. 2008
- Use of a single anti-Xa calibration curve is adequate for monitoring enoxaparin and tinzaparin levels in children. Thrombosis Research. 122:867-869. 2008
- Utility of aPTT in monitoring unfractionated heparin in children. Thrombosis Research. 122:135-136. 2008
- Inhibition of the Thrombin-Thrombomodulin by a Covalent Antithrombin-Heparin.. Blood. 110:2693-2693. 2007
- Risk Factors Predisposing to Thromboembolism in Children with Cancer.. Blood. 110:1633-1633. 2007
- Neonatal Renal Vein Thrombosis: Review of the English-Language Literature Between 1992 and 2006. Pediatrics. 120:e1278-e1284. 2007
- Enoxaparin Use in the Neonatal Intensive Care Unit: Experience Over 8 Years. Pharmacotherapy. 27:1263-1271. 2007
- Quantitative analysis of catheter roughness induced by cutting and manipulation: a potential prothrombotic risk. Blood Coagulation and Fibrinolysis. 18:531-536. 2007
- Utilization of recombinant activated factor VII in southern Ontario in 85 patients with and without haemophilia. Haemophilia. 13:518-526. 2007
- Thromboembolism in children with sarcoma. Pediatric Blood and Cancer. 49:171-176. 2007
- EFFECT OF AGE ON THE RELATIONSHIP BETWEEN RATE OF HEPARIN-CATALYZED INHIBITION OF COAGULATION FACTORS BY ANTITHROMBIN AND IN VIVO PLASMA CONCENTRATION. Journal of Thrombosis and Haemostasis. 5:p-w-052-p-w-052. 2007
- MANAGEMENT OF VENOUS AND ARTERIAL THROMBOSIS IN CHILDREN. Journal of Thrombosis and Haemostasis. 5:sym-w-060-sym-w-060. 2007
- NEONATAL RENAL VEIN THROMBOSIS - 15 YEARS OF LITERATURE. Journal of Thrombosis and Haemostasis. 5:p-s-591-p-s-591. 2007
- Hemorrhagic Complications in Pediatric Hematologic Malignancies. Seminars in Vascular Medicine. 33:408-415. 2007
- Thromboembolic Complications in Pediatric Hematologic Malignancies. Seminars in Vascular Medicine. 33:416-426. 2007
- A practical approach to hemophilia care in children. Paediatrics and Child Health. 12:381-383. 2007
- Trends in the utilization and wastage of coagulation factor concentrates: the application of a regional tracking programme. Haemophilia. 13:271-278. 2007
- Validity, Reliability, and Responsiveness of a New Measure of Health-Related Quality of Life in Children with Immune Thrombocytopenic Purpura: The Kids’ ITP Tools. Journal of Pediatrics. 150:510-515.e1. 2007
- Chronic Immune Thrombocytopenic Purpura in Children. Journal of Pediatric Hematology/Oncology. 29:95-100. 2007
- Analysis of Inhibition Rate Enhancement by Covalent Linkage of Antithrombin to Heparin as a Potential Predictor of Reaction Mechanism. Journal of Biochemistry. 141:25-35. 2007
- Covalent antithrombin–heparin complexes. Thrombosis Research. 120:151-160. 2007
- Effect of substrate and fibrin polymerization inhibitor on determination of plasma thrombin generation in vitro. Thrombosis Research. 119:667-677. 2007
- Monitoring Unfractionated Heparin (UFH) therapy: Which Anti Factor Xa assay is appropriate?. Thrombosis Research. 120:347-351. 2007
- Postnatale Behandlung der neonatalen Alloimmunthrombozytopenie: Systematische Literatursuche und Umfrage in Deutschland und Kanada. Zeitschrift für Geburtshilfe und Neonatologie. 211. 2007
- Protein adsorption on polyurethane catheters modified with a novel antithrombin‐heparin covalent complex. Journal of Biomedical Materials Research - Part A. 80A:216-225. 2007
- Reversal of anti-thrombin activity using protamine sulfate. Experience in a neonate with a 10-fold overdose of enoxaparin. Thrombosis Research. 120:303-305. 2007
- The use of low molecular weight heparins in pediatrics: Two cases that highlight potential risks to patient safety. Thrombosis Research. 121:281-282. 2007
- Chronic performance of polyurethane catheters covalently coated with ATH complex: A rabbit jugular vein model. Clinical Materials. 27:5107-5117. 2006
- Erratum: The fibrinolytic system in newborns and children (Clinical Laboratory (2006) vol. 52 (115-124)). Clinical Laboratory. 52:324. 2006
- Management of asymptomatic proteinuria in children: Role of the general practitioner. Hong Kong Practitioner. 28:383-387. 2006
- Selective cleavage of heparin using aqueous 2-hydroxypyridine: Production of an aldose-terminating fragment with high anticoagulant activity. Biochemical and Biophysical Research Communications. 346:946-957. 2006
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preprints
- Treatment Induced Cerebral Sinus Venous Thrombosis in Childhood Acute Lymphoblastic Leukemia: New Risk Factors to Consider 2021
- Randomised Controlled Trial of Rivaroxaban Compared to Standard Anticoagulants for the Treatment of Acute Venous Thromboembolism in Children 2019
- Rivaroxaban for Treatment of Paediatric Venous Thromboembolism. An EINSTEIN-Jr Phase 3 Dose-Exposure-Response Evaluation 2019