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Randomized, Controlled Trial of Individualized...
Journal article

Randomized, Controlled Trial of Individualized Heparin and Protamine Management in Infants Undergoing Cardiac Surgery With Cardiopulmonary Bypass

Abstract

OBJECTIVES: We sought to determine whether infants (younger than 1 year old) had similar clinical benefits with individualized anticoagulation management as older children and adult undergoing cardiopulmonary bypass (CPB). BACKGROUND: Individualized heparin and protamine management in older children and adults undergoing CPB has been associated with improved clinical outcomes.

Authors

Gruenwald CE; Manlhiot C; Chan AK; Crawford-Lean L; Foreman C; Holtby HM; Van Arsdell GS; Richards R; Moriarty H; McCrindle BW

Journal

Journal of the American College of Cardiology, Vol. 56, No. 22, pp. 1794–1802

Publisher

Elsevier

Publication Date

11 2010

DOI

10.1016/j.jacc.2010.06.046

ISSN

0735-1097