Journal article
Longer Blood Storage Is Associated With Suboptimal Outcomes in High-Risk Pediatric Cardiac Surgery
Abstract
BACKGROUND: The negative effects of long-term storage of allogeneic red blood cells (RBCs) on outcomes in adult cardiac surgery have been established, but evidence of a similar effect in pediatric cardiac surgery is limited.
METHODS: The weighted average duration of storage for RBC units used in 1,225 pediatric cardiac operations was determined. Operations were divided into high RBC use (more than 4 units or more than 150 mL/kg) or low RBC use. …
Authors
Manlhiot C; McCrindle BW; Menjak IB; Yoon H; Holtby HM; Brandão LR; Chan AK; Schwartz SM; Sivarajan VB; Crawford-Lean L
Journal
The Annals of Thoracic Surgery, Vol. 93, No. 5, pp. 1563–1569
Publisher
Elsevier
Publication Date
May 2012
DOI
10.1016/j.athoracsur.2011.08.075
ISSN
0003-4975
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentBlood PreservationBlood SafetyCardiac Surgical ProceduresChildChild, PreschoolCohort StudiesDatabases, FactualEducation, Medical, ContinuingErythrocyte CountErythrocyte TransfusionFemaleFollow-Up StudiesHeart Defects, CongenitalHospital MortalityHumansInfantLinear ModelsLogistic ModelsMaleMultivariate AnalysisPostoperative ComplicationsRetrospective StudiesRisk AssessmentSurvival AnalysisTime FactorsTransplantation, HomologousTreatment Outcome