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Topical nitroglycerin ointment as salvage therapy...
Journal article

Topical nitroglycerin ointment as salvage therapy for peripheral tissue ischemia in newborns: a systematic review

Abstract

BACKGROUND: Topical nitroglycerin (TNG) ointment has been used for almost 3 decades to treat neonatal peripheral tissue ischemia, but this product is now no longer being produced by its Canadian manufacturer. Our aim was to investigate the efficacy and safety of TNG products in newborns in neonatal intensive care units. METHODS: In this systematic review we searched Embase, CINAHL, MEDLINE, PubMed and Web of Science from inception to April 2020 …

Authors

Sushko K; Litalien C; Ferruccio L; Gilpin A; Mazer-Amirshahi M; Chan AK; van den Anker J; Lacaze-Masmonteil T; Samiee-Zafarghandy S

Journal

CMAJ Open, Vol. 9, No. 1, pp. e252–e260

Publisher

Joule

Publication Date

January 2021

DOI

10.9778/cmajo.20200129

ISSN

2291-0026