Journal article
Evaluation for inherited and acquired prothrombotic defects predisposing to symptomatic thromboembolism in children with acute lymphoblastic leukemia: a protocol for a prospective, observational, cohort study
Abstract
BackgroundThromboembolism (TE) is a serious complication in children with acute lymphoblastic leukemia (ALL). The incidence of symptomatic thromboembolism is as high as 14% and case fatality rate of ~15%. Further, development of thromboembolism interferes with the scheduled chemotherapy with potential impact on cure rates. The exact pathogenesis of ALL-associated thromboembolism is unknown. Concomitant administration of asparaginase and …
Authors
Athale UH; Laverdiere C; Nayiager T; Delva Y-L; Foster G; Thabane L; Chan AK
Journal
BMC Cancer, Vol. 17, No. 1,
Publisher
Springer Nature
Publication Date
December 2017
DOI
10.1186/s12885-017-3306-5
ISSN
1471-2407