Epidemiology, etiology, and pathophysiology of infection-associated venous thromboembolism in children

Introduction Venous thromboembolic events (VTE) are increasingly being recognized in children. The clinical spectrum of VTE constitutes deep venous thrombosis (DVT) and pulmonary embolism (PE). Unlike in adults, VTE in children is usually secondary to complications of a primary illness like sepsis, cancer or treatment of primary illness including placement of central venous lines (CVLs) and surgical intervention for correction of underlying …