Journal article
Evaluation of an automated method for measuring von Willebrand factor activity in clinical samples without ristocetin
Abstract
INTRODUCTION: The development of an automated, von Willebrand factor (VWF) activity assay, Innovance(®) VWF Ac (VWF:Ac), which measures VWF binding to the platelet receptor glycoprotein Ibα without ristocetin, led us to evaluate the assay for diagnosing von Willebrand disease (VWD) and monitoring therapy.
METHODS: After validating that the assay could be performed on an instrument from a different manufacturer, we compared VWF:Ac to VWF …
Authors
Graf L; Moffat KA; Carlino SA; Chan AKC; Iorio A; Giulivi A; Hayward CPM
Journal
International Journal of Laboratory Hematology, Vol. 36, No. 3, pp. 341–351
Publisher
Wiley
Publication Date
June 2014
DOI
10.1111/ijlh.12218
ISSN
1751-5521