Journal article
Hormonal Effects upon the Rate of Proliferation of the Murine Plasmacytoma MOPC 315
Abstract
The growth rate of the transplantable murine plasmacytoma MOPC 315 is decreased by daily injections of 2 mg cortisol. Estradiol injections (0.01 mg/day) have a slight stimulatory effect while testosterone has no detectable effect. Growth rate is unaffected by propylthiouracil, triiodothyronine, and growth hormone. MOPC 315 contains glucocorticoid binding proteins which bind 3H-dexamethasone with high affinity. In intact cells there are 3-4 x …
Authors
Chan AK; Davis JM; Thompson A
Journal
Oncology, Vol. 37, No. 6, pp. 411–417
Publisher
Karger Publishers
Publication Date
1980
DOI
10.1159/000225482
ISSN
0030-2414