Enzyme Activation
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Overview
subject area of
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17β-Estradiol Modulates Mechanical Strain-induced MAPK Activation in Mesangial Cells Academic Article
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A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function Journal Articles
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A Control Switch for Prothrombinase Journal Articles
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A High Affinity Interaction of Plasminogen with Fibrin Is Not Essential for Efficient Activation by Tissue-type Plasminogen Activator Academic Article
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A Small Molecule Discrimination Map of the Antibiotic Resistance Kinome Academic Article
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A dopamine-sensitive adenylate cyclase in anterior limbic cortex and mesolimbic region of primate brain Academic Article
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AEG3482 Is an Antiapoptotic Compound that Inhibits Jun Kinase Activity and Cell Death through Induced Expression of Heat Shock Protein 70 Journal Articles
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AMP-activated protein kinase, fatty acid metabolism, and insulin sensitivity Academic Article
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AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging Journal Articles
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AMPK: mediating the metabolic effects of salicylate-based drugs? Journal Articles
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Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression Academic Article
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Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes Academic Article
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Actions of growth factors in the follicle Journal Articles
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Activated Protein C Up-Regulates IL-10 and Inhibits Tissue Factor in Blood Monocytes Academic Article
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Activated protein C resistance, factor V Leiden and peripheral vascular disease. Academic Article
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Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII Academic Article
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Activation by Exercise of Human Skeletal Muscle Pyruvate Dehydrogenase In Vivo Journal Articles
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Activation of Escherichia coli F1-ATPase by lauryldimethylamine oxide and ethylene glycol: relationship of ATPase activity to the interaction of the .epsilon. and .beta. subunits Academic Article
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Activation of MMP-2 as a key event in oxidative stress injury to the heart Academic Article
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Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells Academic Article
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Activation of factor V during intrinsic and extrinsic coagulation. Inhibition by heparin, hirudin and d-Phe-Pro-Arg-Ch2Cl Academic Article
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Activation of mesangial cell MAPK in responseto homocysteine Journal Articles
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Activation of p38 mitogen-activated protein kinase during normal mitosis in the developing retina Journal Articles
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Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells Academic Article
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Activation of the Novel Prothrombinase, fgl2, as a Basis for the Pregnancy Complications Spontaneous Abortion and Pre-eclampsia Academic Article
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Activation of the stress-activated JNK and p38 MAP kinases in human cells by Photofrin-mediated photodynamic therapy Academic Article
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Active Site Interference and Asymmetric Activation in the Chemotaxis Protein Histidine Kinase CheA Academic Article
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Active Subunits of Transaldolase Bound to Sepharose Academic Article
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Acyl Chain Dependence of Diacylglycerol Activation of Protein Kinase C Activityin Vitro Academic Article
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Adenosine kinase and ribokinase – the RK family of proteins Journal Articles
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Adrenergic regulation of HSL serine phosphorylation and activity in human skeletal muscle during the onset of exercise Academic Article
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Advances in Antithrombotic Therapy: Novel Agents Academic Article
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Akt Is Activated in Response to an Apoptotic Signal Journal Articles
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An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator Academic Article
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An overview of the mechanism of action of antithrombin and its inherited deficiency states Academic Article
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Anticoagulant Mechanisms of Orgaran (Org 10172) and Its Fraction with High Affinity to Antithrombin III (Org 10849) Academic Article
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Antifibrotic Effects of a Recombinant Adeno-Associated Virus Carrying Small Interfering RNA Targeting TIMP-1 in Rat Liver Fibrosis Academic Article
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Apoptosis induction by eIF5A1 involves activation of the intrinsic mitochondrial pathway Journal Articles
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Aryl hydrocarbon receptor control of a disease tolerance defence pathway Academic Article
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Aspartate transcarbamoylase: loss of homotropic but not heterotropic interactions upon modification of the catalytic subunit with a bifunctional reagent Academic Article
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Assessment of the downstream portion of the mitochondrial pathway of caspase activation in patients with acute myeloid leukemia Academic Article
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Association of Neurofilament Proteins with Neuronal Cdk5 Activator Journal Articles
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BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38− cells, through activation of protein kinase Cβ Academic Article
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Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts Academic Article
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Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair Academic Article
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CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK Journal Articles
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Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man Academic Article
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Caspase-12 Dampens the Immune Response to Malaria Independently of the Inflammasome by Targeting NF-κB Signaling Academic Article
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Caspase-8 Activation and Bid Cleavage Contribute to MCF7 Cellular Execution in a Caspase-3-dependent Manner during Staurosporine-mediated Apoptosis Academic Article
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Catabolism of Aggrecan by Explant Cultures of Human Articular Cartilage in the Presence of Retinoic Acid Academic Article
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Caveolin-1 phosphorylation is required for stretch-induced EGFR and Akt activation in mesangial cells Academic Article
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Cell death attenuation by `Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex Academic Article
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Cells that constitutively express the herpes simplex virus immediate-early protein ICP4 allow efficient activation of viral delayed-early genes in trans Journal Articles
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Cellular Energy Sensing and Metabolism—Implications for Treating Diabetes: The 2017 Outstanding Scientific Achievement Award Lecture Journal Articles
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Characterization of CHO-K1 cells stably expressing PDE-IV enzymes Journal Articles
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Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells Journal Articles
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Characterization of two members of a novel malic enzyme class Academic Article
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Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53 Academic Article
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Chemical and biological reactivity of insoluble nickel compounds and the bioinorganic chemistry of nickel. Academic Article
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Clear cell renal cell carcinoma induces fibroblast-mediated production of stromal periostin Academic Article
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Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study Academic Article
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Co-existence of high levels of the PTEN protein with enhanced Akt activation in renal cell carcinoma Academic Article
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Co-operation between Polymerases and Nucleotide Synthetases in the RNA World Academic Article
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Colchicine attenuates renal injury in a model of hypertensive chronic kidney disease Academic Article
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Collagen I induction by high glucose levels is mediated by epidermal growth factor receptor and phosphoinositide 3-kinase/Akt signalling in mesangial cells Academic Article
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Comparative effects of heparin and LMW heparin on hemostasis Conferences
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Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress Academic Article
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Conformation of cross-linked aspartate transcarbamoylase Journal Articles
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Conformations of bound nucleoside triphosphate effectors in aspartate transcarbamylase. Evidence for the London-Schmidt model by transferred nuclear Overhauser effects Academic Article
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Contactin-1 Reduces E-Cadherin Expression Via Activating AKT in Lung Cancer Academic Article
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Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase Journal Articles
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Conversion of Low Density Lipoprotein-associated Phosphatidylcholine to Triacylglycerol by Primary Hepatocytes Academic Article
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Copper effects on key metabolic enzymes and mitochondrial membrane potential in gills of the estuarine crab Neohelice granulata at different salinities Academic Article
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Corneal epithelial cell biocompatibility to silicone hydrogel and conventional hydrogel contact lens packaging solutions. Academic Article
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Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va Academic Article
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Cyclin-dependent Kinase 5 (Cdk5) Activation Domain of Neuronal Cdk5 Activator Academic Article
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Cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activators Academic Article
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Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIα Academic Article
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Depletion of poly(ADP-ribose) polymerase-1 reduces host cell reactivation of a UV-damaged adenovirus-encoded reporter gene in human dermal fibroblasts Academic Article
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Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis Academic Article
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Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease Journal Articles
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Dissociation of AMPK activity and ACCβ phosphorylation in human muscle during prolonged exercise Academic Article
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EGFR-PLCγ1 signaling mediates high glucose-induced PKCβ1-Akt activation and collagen I upregulation in mesangial cells Academic Article
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EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP) Academic Article
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ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53 Academic Article
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ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function Academic Article
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ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response. Academic Article
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Effects of Activators of Different Intracellular Signaling Pathways on Steroid Production by Goldfish Vitellogenic Ovarian Follicles Journal Articles
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Effects of high fat provision on muscle PDH activation and malonyl-CoA content in moderate exercise Academic Article
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Effects of morphine on dopamine-stimulated adenylate cyclase and on cyclic GMP formation in primate brain amygdaloid nucleus Academic Article
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Effects of peroxide on endothelial nitric oxide synthase in coronary arteries. Academic Article
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Effects of reduced free fatty acid availability on hormone-sensitive lipase activity in human skeletal muscle during aerobic exercise Academic Article
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Effects of reduced free fatty acid availability on skeletal muscle PDH activation during aerobic exercise Academic Article
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Elevated n-3 fatty acids in a high-fat diet attenuate the increase in PDH kinase activity but not PDH activity in human skeletal muscle Journal Articles
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Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis Academic Article
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Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event Academic Article
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Enhanced pyruvate dehydrogenase activity does not affect muscle O2uptake at onset of intense exercise in humans Academic Article
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Enhancement of Dopamine-Stimulated Adenylate Cyclase Activity in Rat Caudate after Lesions in Substantia Nigra: Evidence for Denervation Supersensitivity Academic Article
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Enolpyruvyl Activation by Enolpyruvylshikimate-3-phosphate Synthase Academic Article
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Exosite 2-Directed Ligands Attenuate Protein C Activation by the Thrombin–Thrombomodulin Complex Journal Articles
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Factors affecting solubilized dopamine-sensitive adenylate cyclase Journal Articles
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Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubes Academic Article
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Functional Screening of Pharmacological Chaperones via Restoration of Enzyme Activity upon Denaturation Academic Article
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Functional role of M2
and M3
muscarinic receptors in the urinary bladder of rats in vitro
and in vivo Journal Articles
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Further Evidence for Two Functional Forms of Prothrombinase Each Specific for Either of the Two Prothrombin Activation Cleavages Academic Article
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G-protein-coupled receptor independent, immunomodulatory properties of chemokine CXCL9 Journal Articles
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Gross thymic extract, Thymax, induces apoptosis in human breast cancer cells in vitro through the mitochondrial pathway. Conferences
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HIV-1 gp120 Induces TLR2- and TLR4-Mediated Innate Immune Activation in Human Female Genital Epithelium Academic Article
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Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity Academic Article
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Heparan Sulfate Interacting Protein (HIP/L29) Negatively Regulates Growth Responses to Basic Fibroblast Growth Factor in Gingival Fibroblasts Journal Articles
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Heparan sulfate and dermatan sulfate inhibit the generation of thrombin activity in plasma by complementary pathways Journal Articles
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Heparan sulfate and dermatan sulfate inhibit the generation of thrombin activity in plasma by complementary pathways. Journal Articles
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Heparin with low affinity to antithrombin III inhibits the activation of prothrombin in normal plasma Academic Article
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Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols Academic Article
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High activity of mitochondrial glycerophosphate dehydrogenase and glycerophosphate-dependent ROS production in prostate cancer cell lines Academic Article
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High glucose-induced RhoA activation requires caveolae and PKCβ1-mediated ROS generation Academic Article
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Highly active, lipase silicone elastomers Academic Article
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Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic coagulation pathway Academic Article
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Hormone-sensitive lipase activity and triacylglycerol hydrolysis are decreased in rat soleus muscle by cyclopiazonic acid Academic Article
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Human cells deficient in transcription-coupled repair show prolonged activation of the Jun N-terminal kinase and increased sensitivity following cisplatin treatment Journal Articles
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Hyperinsulinemia-induced vascular smooth muscle cell (VSMC) migration and proliferation is mediated by converging mechanisms of mitochondrial dysfunction and oxidative stress Journal Articles
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Identification and Structure Characterization of a Cdk Inhibitory Peptide Derived from Neuronal-specific Cdk5 Activator Academic Article
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Identification and characterization of human ribokinase and comparison of its properties withE. coliribokinase and human adenosine kinase Academic Article
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Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells Journal Articles
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Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2) Academic Article
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Identification of a hTid-1 mutation which sensitizes gliomas to apoptosis Academic Article
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Impact of Multipurpose Solutions Released from Contact Lenses on Corneal Cells Academic Article
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Impaired Activation of AMP-Kinase and Fatty Acid Oxidation by Globular Adiponectin in Cultured Human Skeletal Muscle of Obese Type 2 Diabetics Academic Article
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In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes Journal Articles
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Inactivation of human muscle Na+-K+-ATPase in vitro during prolonged exercise is increased with hypoxia Academic Article
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Incorporation of Fragment X into Fibrin Clots Renders Them More Susceptible to Lysis by Plasmin Academic Article
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Increased PFK activity and GLUT4 protein content in McArdle's disease Conferences
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Increased Placental Apoptosis in Maternal Food Restricted Gestations: Role of the Fas Pathway Academic Article
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Inhibition and Activation of Human Lactate Dehydrogenase by Urea Academic Article
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Inhibition of Actomyosin ATPase by High Concentrations of 5-Hydroxytryptamine. Possible Basis of Lesion in 5HT-Induced Experimental Myopathy Journal Articles
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Inhibition of Calpain Is a Component of Nitric Oxide-Induced Down-Regulation of Human Mast Cell Adhesion Journal Articles
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Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation Academic Article
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Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS Academic Article
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Insulin Activates a p21-activated Kinase in Muscle Cells via Phosphatidylinositol 3-Kinase Academic Article
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Insulin acutely decreases hepatic fatty acid synthase activity Academic Article
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Insulin-like growth factors inhibit podocyte apoptosis through the PI3 kinase pathway Academic Article
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Interaction of D-phenylalanine with Co(II)-substituted rabbit muscle pyruvate kinase: kinetic and optical properties Academic Article
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Interaction of c-Abl and p73α and their collaboration to induce apoptosis Academic Article
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Interactions between ROS and AMP kinase activity in the regulation of PGC-1α transcription in skeletal muscle cells Academic Article
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Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man Academic Article
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Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells Academic Article
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Kinase-specific responsiveness to incremental contractile activity in skeletal muscle with low and high mitochondrial content Academic Article
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Kinetic Analysis of a Unique Direct Prothrombinase, fgl2, and Identification of a Serine Residue Critical for the Prothrombinase Activity Journal Articles
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Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function Academic Article
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Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis Journal Articles
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Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells Academic Article
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Lys 42/43/44 and Arg 12 of thrombin-activable fibrinolysis inhibitor comprise a thrombomodulin exosite essential for its antifibrinolytic potential Academic Article
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Maintenance of caspase-3 proenzyme dormancy by an intrinsic “safety catch” regulatory tripeptide Academic Article
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Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα Academic Article
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Mechanical Stretch-Induced Signal Transduction in Cultured Mesangial Cells Journal Articles
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Mechanical stretch-induced RhoA activation is mediated by the RhoGEF Vav2 in mesangial cells Journal Articles
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Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK Academic Article
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Mechanisms by Which Soluble Endothelial Cell Protein C Receptor Modulates Protein C and Activated Protein C Function Academic Article
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Mechanisms for Inhibition of the Generation of Thrombin Activity by Sulfated Polysaccharides Journal Articles
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Mesangial cell signaling cascades in response to mechanical strain and glucose Academic Article
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Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity Academic Article
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Modulation of Human Airway Smooth Muscle Migration by Lipid Mediators and Th-2 Cytokines Academic Article
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Modulation of Monocyte Function by Activated Protein C, a Natural Anticoagulant Academic Article
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Modulation of the Enzymatic Activity of α-Thrombin by Polyanions: Consequences on Intrinsic Activation of Factor V and Factor VIII Academic Article
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Molecular Mechanism of the Enterococcal Aminoglycoside 6‘-N-Acetyltransferase‘: Role of GNAT-Conserved Residues in the Chemistry of Antibiotic Inactivation Journal Articles
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Molecular structural analysis of a novel and de-novo mutation in theSERPINC1gene associated with type 1 antithrombin deficiency Academic Article
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NMR Structures Reveal How Oxidation Inactivates Thrombomodulin Academic Article
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NO+but not NO radical relaxes airway smooth muscle via cGMP-independent release of internal Ca2+ Journal Articles
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NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway Academic Article
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Native low-density lipoprotein induces endothelial nitric oxide synthase dysfunction: role of heat shock protein 90 and caveolin-1 Academic Article
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Neuronal Cdc2-like kinase: from cell cycle to neuronal function Journal Articles
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New isolate of Streptomyces sp. with novel thermoalkalotolerant cellulases Academic Article
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Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells Academic Article
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Nitric oxide modulates stretch activation of mitogen-activated protein kinases in mesangial cells Journal Articles
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Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations Academic Article
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O2uptake kinetics, pyruvate dehydrogenase activity, and muscle deoxygenation in young and older adults during the transition to moderate-intensity exercise Journal Articles
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On the ouabain-sensitive potassium activated p-nitrophenyl phosphatase activity of vascular muscle plasma membranes. Academic Article
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Optimization of a Fluorescence-based Lysozyme Activity Assay for Contact Lens Studies Academic Article
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Oxidative stress and antioxidant enzyme upregulation in SOD1-G93A mouse skeletal muscle Academic Article
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Oxidative stress and metabolic responses to copper in freshwater- and seawater-acclimated killifish, Fundulus heteroclitus Journal Articles
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PDH activation by dichloroacetate reduces TCA cycle intermediates at rest but not during exercise in humans Journal Articles
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PDH-E1α Dephosphorylation and Activation in Human Skeletal Muscle During Exercise Academic Article
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PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells Academic Article
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PTEN inhibits BMI1 function independently of its phosphatase activity Academic Article
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Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts Academic Article
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Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells Academic Article
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Pancratistatin induces apoptosis and autophagy in metastatic prostate cancer cells Academic Article
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Patients with severe sepsis vary markedly in their ability to generate activated protein C Academic Article
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Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis Academic Article
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Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death Academic Article
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Pharmacological inhibition of forskolin-stimulated adenylate cyclase activity in rat brain by melatonin, its analogs, and diazepam Academic Article
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Phosphoester-transfer mechanism of an RNA-cleaving acidic deoxyribozyme revealed by radioactivity tracking and enzymatic digestion Academic Article
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Phosphorylation of PITSLRE p110 Isoforms Accompanies Their Processing by Caspases during Fas-mediated Cell Death Academic Article
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Plasmin accelerates platelet‐dependent prothrombinase formation without activating the platelets Academic Article
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Pleiotropic Action of AP-1 in v-Src-Transformed Cells Academic Article
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Prior heavy exercise elevates pyruvate dehydrogenase activity and speeds O2uptake kinetics during subsequent moderate-intensity exercise in healthy young adults Academic Article
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Pro- and macroglycogenolysis during repeated exercise: roles of glycogen content and phosphorylase activation Academic Article
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Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7 Academic Article
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Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation Academic Article
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Properties of potassium activatedp-nitrophenyl phosphatase of plasma membranes isolated from rat stomach muscle Academic Article
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Pyruvate dehydrogenase activation in inactive muscle during and after maximal exercise in men Academic Article
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Rapid upregulation of pyruvate dehydrogenase kinase activity in human skeletal muscle during prolonged exercise Academic Article
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Receptor-mediated protein kinase activation and the mechanism of transmembrane signaling in bacterial chemotaxis Academic Article
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Reconstitution of rabbit sarcoplasmic reticulum calcium ATPase in a series of phosphatidylcholines containing a saturated and an unsaturated chain: suggestion of an optimal lipid environment Journal Articles
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Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M Academic Article
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Regulation of NADH/CoQ Oxidoreductase: Do Phosphorylation Events Affect Activity? Academic Article
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Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain Academic Article
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Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6. Academic Article
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Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis Academic Article
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Requirement of Lysine Residues Outside of the Proposed Pentasaccharide Binding Region for High Affinity Heparin Binding and Activation of Human Antithrombin III Academic Article
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Requirement of p38 stress-activated MAP kinase for cell death in the developing retina depends on the stage of cell differentiation Journal Articles
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Rh proteins and NH4+-activated Na+-ATPase in the Magadi tilapia (Alcolapia grahami), a 100% ureotelic teleost fish Academic Article
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RhoA Activation in Mesangial Cells by Mechanical Strain Depends on Caveolae and Caveolin-1 Interaction Journal Articles
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RhoA/Rho-Kinase Contribute to the Pathogenesis of Diabetic Renal Disease Academic Article
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Role of sarcolemmal changes in cardiac pathophysiology. Journal Articles
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Role of α-Helical Coiled-coil Interactions in Receptor Dimerization, Signaling, and Adaptation during Bacterial Chemotaxis Academic Article
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SIPL1 enhances the proliferation, attachment, and migration of CHO cells by inhibiting PTEN function Academic Article
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STABILIZATION OF DIHYDROFOLATE REDUCTASE BY INHIBITORS IN VIVO AND IN VITRO Journal Articles
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Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis Academic Article
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Salicylate improves macrophage cholesterol homeostasis via activation of Ampk Academic Article
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Selenite Negatively Regulates Caspase-3 through a Redox Mechanism Academic Article
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Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells Academic Article
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Skeletal muscle metabolism is unaffected by DCA infusion and hyperoxia after onset of intense aerobic exercise Academic Article
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Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling Academic Article
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Soluble fibrin degradation products potentiate tissue plasminogen activator-induced fibrinogen proteolysis. Academic Article
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Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes Journal Articles
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Stimulation of Na+
, K+
-pump activity in skeletal muscle by methylxanthines: evidence and proposed mechanisms Conference Paper
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Stretch-induced Raf-1 activation in mesangial cells requires actin cytoskeletal integrity Academic Article
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Structure Activity Studies on the Crinane Alkaloid Apoptosis-inducing Pharmacophore Academic Article
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Studies on Protein Subunits Academic Article
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Sublethal mechanisms of Pb and Zn toxicity to the purple sea urchin (Strongylocentrotus purpuratus) during early development Academic Article
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Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability Academic Article
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Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy. Journal Articles
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Synergistic effects between FSH and 1,1-dichloro-2,2-bis(P-chlorophenyl)ethylene (P,P'-DDE) on human granulosa cell aromatase activity Academic Article
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Synthesis and Biological Activity of a Focused Library of Mitogen-activated Protein Kinase Phosphatase Inhibitors Academic Article
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TGFβ-induced RhoA activation and fibronectin production in mesangial cells require caveolae Academic Article
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Telomere elongation in immortal human cells without detectable telomerase activity. Journal Articles
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Tentative de localisation histochimique d'une ATPase-Na+-K+ au niveau de l'�pith�lium pseudobranchial des T�l�ost�ens Academic Article
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Thallous ion activation of p-nitrophenylphosphatase of rat myometrium plasma membrane Academic Article
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The
AMPK
agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting Academic Article
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The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase Journal Articles
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The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2 Journal Articles
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The Chirality of Phosphatidylserine and the Activation of Protein Kinase C Academic Article
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The Effects of Leptin on Airway Smooth Muscle Responses Academic Article
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The Human Cationic Peptide LL-37 Induces Activation of the Extracellular Signal-Regulated Kinase and p38 Kinase Pathways in Primary Human Monocytes Academic Article
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The Protein-Protein Interaction-Mediated Inactivation of PTEN Academic Article
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The Roles of Selected Arginine and Lysine Residues of TAFI (Pro-CPU) in Its Activation to TAFIa by the Thrombin-Thrombomodulin Complex Journal Articles
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The Suppressor of Cytokine Signaling 3 Inhibits Leptin Activation of AMP-Kinase in Cultured Skeletal Muscle of Obese Humans Academic Article
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The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades. Journal Articles
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The acute effects of differential dietary fatty acids on human skeletal muscle pyruvate dehydrogenase activity Academic Article
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The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung Academic Article
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The decrease in phosphatidylinositol 4,5-bisphosphate in ADP-stimulated washed rabbit platelets is not primarily due to phospholipase C activation Academic Article
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The impact of the endothelial protein C receptor on thrombin generation and clot lysis Journal Articles
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The inhibition of thrombin-dependent positive-feedback reactions is critical to the expression of the anticoagulant effect of heparin Academic Article
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The lnterleukin-5/Receptor Interaction Activates Lyn and Jak2 Tyrosine Kinases and Propagates Signals via the Ras-Raf-1-MAP Kinase and the Jak-STAT Pathways in Eosinophils Conference Paper
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The mechanism of Ca2+ regulation of vascular smooth muscle thin filaments by caldesmon and calmodulin. Academic Article
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The microbiota and the gut-brain axis: insights from the temporal and spatial mucosal alterations during colonisation of the germfree mouse intestine Journal Articles
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The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms Academic Article
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The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus Academic Article
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The plasma concentration of activated protein C appears normal in patients with haemophilia Academic Article
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The proteolytic action of Arvin on human fibrinogen Journal Articles
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The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis Academic Article
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The use of poly(ethylene oxide) for the efficient stabilization of entrapped α-chymotrypsin in silicone elastomers: A chemometric study Academic Article
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Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes Academic Article
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Thrombin Binds to Soluble Fibrin Degradation Products Where it Is Protected From Inhibition by Heparin-Antithrombin but Susceptible to Inactivation by Antithrombin-Independent Inhibitors Journal Articles
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Thrombin Inhibition by Hirudin: How Hirudin Inhibits Thrombin Academic Article
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Thrombin activation rate constant: One-stage chromogenic assay for the extrinsic system Journal Articles
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Thrombin and Antithrombotics Academic Article
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Thrombin-activable Fibrinolysis Inhibitor Attenuates (DD)E-mediated Stimulation of Plasminogen Activation by Reducing the Affinity of (DD)E for Tissue Plasminogen Activator Academic Article
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Thrombin-activatable fibrinolysis inhibitor is activated in vivo in a baboon model of Escherichia coli induced sepsis Academic Article
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Toxic effects of the herbicide Roundup in the guppy Poecilia vivipara acclimated to fresh water Academic Article
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Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis Journal Articles
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Transient pseudothrombocytopenia associated with immune heparin-induced thrombocytopenia complicated by pulmonary embolism Journal Articles
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Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia Journal Articles
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Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages Academic Article
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Tyrosine Phosphorylation of Caspase-8 Abrogates Its Apoptotic Activity and Promotes Activation of c-Src Academic Article
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Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression Academic Article
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Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene Journal Articles
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Zinc delays clot lysis by attenuating plasminogen activation and plasmin-mediated fibrin degradation Journal Articles
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cAMP activation of PKA defines an ancient signaling mechanism Academic Article
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p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade Academic Article
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β‐adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling Journal Articles