Enzyme Activation Concept

subject area of

• 17β-Estradiol Modulates Mechanical Strain-induced MAPK Activation in Mesangial Cells  Journal Articles
• Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis  Journal Articles
• A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function  Journal Articles
• A Control Switch for Prothrombinase  Journal Articles
• A High Affinity Interaction of Plasminogen with Fibrin Is Not Essential for Efficient Activation by Tissue-type Plasminogen Activator  Journal Articles
• A Small Molecule Discrimination Map of the Antibiotic Resistance Kinome  Journal Articles
• A dopamine-sensitive adenylate cyclase in anterior limbic cortex and mesolimbic region of primate brain  Journal Articles
• AEG3482 Is an Antiapoptotic Compound that Inhibits Jun Kinase Activity and Cell Death through Induced Expression of Heat Shock Protein 70  Journal Articles
• AMP-activated protein kinase, fatty acid metabolism, and insulin sensitivity  Journal Articles
• AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging  Journal Articles
• AMPK: mediating the metabolic effects of salicylate-based drugs?  Journal Articles
• Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression  Journal Articles
• Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes  Journal Articles
• Actions of growth factors in the follicle  Journal Articles
• Activated Protein C Up-Regulates IL-10 and Inhibits Tissue Factor in Blood Monocytes  Journal Articles
• Activated protein C resistance, factor V Leiden and peripheral vascular disease.  Journal Articles
• Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII  Journal Articles
• Activation by Exercise of Human Skeletal Muscle Pyruvate Dehydrogenase In Vivo  Journal Articles
• Activation of Escherichia coli F1-ATPase by lauryldimethylamine oxide and ethylene glycol: relationship of ATPase activity to the interaction of the .epsilon. and .beta. subunits  Journal Articles
• Activation of MMP-2 as a key event in oxidative stress injury to the heart  Journal Articles
• Activation of factor V during intrinsic and extrinsic coagulation. Inhibition by heparin, hirudin and d-Phe-Pro-Arg-Ch2Cl  Journal Articles
• Activation of mesangial cell MAPK in responseto homocysteine  Journal Articles
• Activation of p38 mitogen-activated protein kinase during normal mitosis in the developing retina  Journal Articles
• Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells  Journal Articles
• Activation of the Novel Prothrombinase, fgl2, as a Basis for the Pregnancy Complications Spontaneous Abortion and Pre‐eclampsia  Journal Articles
• Activation of the stress-activated JNK and p38 MAP kinases in human cells by Photofrin-mediated photodynamic therapy  Journal Articles
• Active Site Interference and Asymmetric Activation in the Chemotaxis Protein Histidine Kinase CheA  Journal Articles
• Active Subunits of Transaldolase Bound to Sepharose  Journal Articles
• Acyl Chain Dependence of Diacylglycerol Activation of Protein Kinase C Activityin Vitro  Journal Articles
• Adenosine kinase and ribokinase – the RK family of proteins  Journal Articles
• Adrenergic regulation of HSL serine phosphorylation and activity in human skeletal muscle during the onset of exercise  Journal Articles
• Advances in Antithrombotic Therapy: Novel Agents  Journal Articles
• Akt Is Activated in Response to an Apoptotic Signal  Journal Articles
• An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator  Journal Articles
• Anticoagulant Mechanisms of Orgaran (Org 10172) and Its Fraction with High Affinity to Antithrombin III (Org 10849)  Journal Articles
• Antifibrotic Effects of a Recombinant Adeno-Associated Virus Carrying Small Interfering RNA Targeting TIMP-1 in Rat Liver Fibrosis  Journal Articles
• Apoptosis induction by eIF5A1 involves activation of the intrinsic mitochondrial pathway  Journal Articles
• Aryl hydrocarbon receptor control of a disease tolerance defence pathway  Journal Articles
• Aspartate transcarbamoylase: loss of homotropic but not heterotropic interactions upon modification of the catalytic subunit with a bifunctional reagent  Journal Articles
• Assessment of the downstream portion of the mitochondrial pathway of caspase activation in patients with acute myeloid leukemia  Journal Articles
• Association of Neurofilament Proteins with Neuronal Cdk5 Activator  Journal Articles
• BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38− cells, through activation of protein kinase Cβ  Journal Articles
• Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts  Journal Articles
• Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair  Journal Articles
• CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK  Journal Articles
• Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man  Journal Articles
• Caspase-12 Dampens the Immune Response to Malaria Independently of the Inflammasome by Targeting NF-κB Signaling  Journal Articles
• Caspase-8 Activation and Bid Cleavage Contribute to MCF7 Cellular Execution in a Caspase-3-dependent Manner during Staurosporine-mediated Apoptosis  Journal Articles
• Catabolism of Aggrecan by Explant Cultures of Human Articular Cartilage in the Presence of Retinoic Acid  Journal Articles
• Caveolin-1 phosphorylation is required for stretch-induced EGFR and Akt activation in mesangial cells  Journal Articles
• Cell death attenuation by `Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex  Journal Articles
• Cells that constitutively express the herpes simplex virus immediate-early protein ICP4 allow efficient activation of viral delayed-early genes in trans  Journal Articles
• Cellular Energy Sensing and Metabolism—Implications for Treating Diabetes: The 2017 Outstanding Scientific Achievement Award Lecture  Journal Articles
• Characterization of CHO-K1 cells stably expressing PDE-IV enzymes  Journal Articles
• Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells  Journal Articles
• Characterization of two members of a novel malic enzyme class  Journal Articles
• Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53  Journal Articles
• Chemical and biological reactivity of insoluble nickel compounds and the bioinorganic chemistry of nickel.  Journal Articles
• Clear cell renal cell carcinoma induces fibroblast-mediated production of stromal periostin  Journal Articles
• Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study  Journal Articles
• Co-existence of high levels of the PTEN protein with enhanced Akt activation in renal cell carcinoma  Journal Articles
• Co-operation between Polymerases and Nucleotide Synthetases in the RNA World  Journal Articles
• Colchicine attenuates renal injury in a model of hypertensive chronic kidney disease  Journal Articles
• Collagen I induction by high glucose levels is mediated by epidermal growth factor receptor and phosphoinositide 3-kinase/Akt signalling in mesangial cells  Journal Articles
• Comparative effects of heparin and LMW heparin on hemostasis  Conferences
• Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress  Journal Articles
• Conformation of cross-linked aspartate transcarbamoylase  Journal Articles
• Conformations of bound nucleoside triphosphate effectors in aspartate transcarbamylase. Evidence for the London-Schmidt model by transferred nuclear Overhauser effects  Journal Articles
• Contactin-1 Reduces E-Cadherin Expression Via Activating AKT in Lung Cancer  Journal Articles
• Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase  Journal Articles
• Conversion of Low Density Lipoprotein-associated Phosphatidylcholine to Triacylglycerol by Primary Hepatocytes  Journal Articles
• Copper effects on key metabolic enzymes and mitochondrial membrane potential in gills of the estuarine crab Neohelice granulata at different salinities  Journal Articles
• Corneal epithelial cell biocompatibility to silicone hydrogel and conventional hydrogel contact lens packaging solutions.  Journal Articles
• Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va  Journal Articles
• Cyclin-dependent Kinase 5 (Cdk5) Activation Domain of Neuronal Cdk5 Activator  Journal Articles
• Cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activators  Journal Articles
• Cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activators  Chapters
• Definition of an electrostatic relay switch critical for the cAMP‐dependent activation of protein kinase A as revealed by the D170A mutant of RIα  Journal Articles
• Depletion of poly(ADP-ribose) polymerase-1 reduces host cell reactivation of a UV-damaged adenovirus-encoded reporter gene in human dermal fibroblasts  Journal Articles
• Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis  Journal Articles
• Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease  Journal Articles
• Dissociation of AMPK activity and ACCβ phosphorylation in human muscle during prolonged exercise  Journal Articles
• EGFR-PLCγ1 signaling mediates high glucose-induced PKCβ1-Akt activation and collagen I upregulation in mesangial cells  Journal Articles
• EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)  Journal Articles
• ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53  Journal Articles
• ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function  Journal Articles
• ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response.  Journal Articles
• Effects of Activators of Different Intracellular Signaling Pathways on Steroid Production by Goldfish Vitellogenic Ovarian Follicles  Journal Articles
• Effects of high fat provision on muscle PDH activation and malonyl-CoA content in moderate exercise  Journal Articles
• Effects of morphine on dopamine-stimulated adenylate cyclase and on cyclic GMP formation in primate brain amygdaloid nucleus  Journal Articles
• Effects of peroxide on endothelial nitric oxide synthase in coronary arteries.  Journal Articles
• Effects of reduced free fatty acid availability on hormone-sensitive lipase activity in human skeletal muscle during aerobic exercise  Journal Articles
• Effects of reduced free fatty acid availability on skeletal muscle PDH activation during aerobic exercise  Journal Articles
• Elevated n-3 fatty acids in a high-fat diet attenuate the increase in PDH kinase activity but not PDH activity in human skeletal muscle  Journal Articles
• Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis  Journal Articles
• Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event  Journal Articles
• Enhanced pyruvate dehydrogenase activity does not affect muscle O₂uptake at onset of intense exercise in humans  Journal Articles
• Enhancement of Dopamine-Stimulated Adenylate Cyclase Activity in Rat Caudate after Lesions in Substantia Nigra: Evidence for Denervation Supersensitivity  Journal Articles
• Enolpyruvyl Activation by Enolpyruvylshikimate-3-phosphate Synthase  Journal Articles
• Exosite 2-Directed Ligands Attenuate Protein C Activation by the Thrombin–Thrombomodulin Complex  Journal Articles
• Factors affecting solubilized dopamine-sensitive adenylate cyclase  Journal Articles
• Fatty acids stimulate AMP‐activated protein kinase and enhance fatty acid oxidation in L6 myotubes  Journal Articles
• Functional Screening of Pharmacological Chaperones via Restoration of Enzyme Activity upon Denaturation  Journal Articles
• Further Evidence for Two Functional Forms of Prothrombinase Each Specific for Either of the Two Prothrombin Activation Cleavages  Journal Articles
• G-protein-coupled receptor independent, immunomodulatory properties of chemokine CXCL9  Journal Articles
• Gross thymic extract, Thymax, induces apoptosis in human breast cancer cells in vitro through the mitochondrial pathway.  Conferences
• HIV-1 gp120 Induces TLR2- and TLR4-Mediated Innate Immune Activation in Human Female Genital Epithelium  Journal Articles
• Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity  Journal Articles
• Heparan Sulfate Interacting Protein (HIP/L29) Negatively Regulates Growth Responses to Basic Fibroblast Growth Factor in Gingival Fibroblasts  Journal Articles
• Heparan sulfate and dermatan sulfate inhibit the generation of thrombin activity in plasma by complementary pathways  Journal Articles
• Heparan sulfate and dermatan sulfate inhibit the generation of thrombin activity in plasma by complementary pathways.  Journal Articles
• Heparin with low affinity to antithrombin III inhibits the activation of prothrombin in normal plasma  Journal Articles
• Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols  Journal Articles
• High activity of mitochondrial glycerophosphate dehydrogenase and glycerophosphate-dependent ROS production in prostate cancer cell lines  Journal Articles
• High glucose-induced RhoA activation requires caveolae and PKCβ1-mediated ROS generation  Journal Articles
• Highly active, lipase silicone elastomers  Journal Articles
• Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic coagulation pathway  Journal Articles
• Hormone-sensitive lipase activity and triacylglycerol hydrolysis are decreased in rat soleus muscle by cyclopiazonic acid  Journal Articles
• Human cells deficient in transcription-coupled repair show prolonged activation of the Jun N-terminal kinase and increased sensitivity following cisplatin treatment  Journal Articles
• Hyperinsulinemia-induced vascular smooth muscle cell (VSMC) migration and proliferation is mediated by converging mechanisms of mitochondrial dysfunction and oxidative stress  Journal Articles
• Identification and Structure Characterization of a Cdk Inhibitory Peptide Derived from Neuronal-specific Cdk5 Activator  Journal Articles
• Identification and characterization of human ribokinase and comparison of its properties with E. coli ribokinase and human adenosine kinase  Journal Articles
• Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells  Journal Articles
• Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2)  Journal Articles
• Identification of a hTid‐1 mutation which sensitizes gliomas to apoptosis  Journal Articles
• Impact of Multipurpose Solutions Released from Contact Lenses on Corneal Cells  Journal Articles
• Impaired Activation of AMP-Kinase and Fatty Acid Oxidation by Globular Adiponectin in Cultured Human Skeletal Muscle of Obese Type 2 Diabetics  Journal Articles
• In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes  Journal Articles
• Inactivation of human muscle Na⁺-K⁺-ATPase in vitro during prolonged exercise is increased with hypoxia  Journal Articles
• Incorporation of Fragment X into Fibrin Clots Renders Them More Susceptible to Lysis by Plasmin  Journal Articles
• Increased PFK activity and GLUT4 protein content in McArdle's disease  Conferences
• Increased Placental Apoptosis in Maternal Food Restricted Gestations: Role of the Fas Pathway  Journal Articles
• Inhibition and Activation of Human Lactate Dehydrogenase by Urea  Journal Articles
• Inhibition of Actomyosin ATPase by High Concentrations of 5-Hydroxytryptamine. Possible Basis of Lesion in 5HT-Induced Experimental Myopathy  Journal Articles
• Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation  Journal Articles
• Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS  Journal Articles
• Insulin Activates a p21-activated Kinase in Muscle Cells via Phosphatidylinositol 3-Kinase  Journal Articles
• Insulin acutely decreases hepatic fatty acid synthase activity  Journal Articles
• Insulin-like growth factors inhibit podocyte apoptosis through the PI3 kinase pathway  Journal Articles
• Interaction of D-phenylalanine with Co(II)-substituted rabbit muscle pyruvate kinase: kinetic and optical properties  Journal Articles
• Interaction of c-Abl and p73α and their collaboration to induce apoptosis  Journal Articles
• Interactions between ROS and AMP kinase activity in the regulation of PGC-1α transcription in skeletal muscle cells  Journal Articles
• Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man  Journal Articles
• Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells  Journal Articles
• Kinase-specific responsiveness to incremental contractile activity in skeletal muscle with low and high mitochondrial content  Journal Articles
• Kinetic Analysis of a Unique Direct Prothrombinase, fgl2, and Identification of a Serine Residue Critical for the Prothrombinase Activity  Journal Articles
• Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function  Journal Articles
• Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis  Journal Articles
• Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells  Journal Articles
• Lys 42/43/44 and Arg 12 of thrombin-activable fibrinolysis inhibitor comprise a thrombomodulin exosite essential for its antifibrinolytic potential  Journal Articles
• Maintenance of caspase-3 proenzyme dormancy by an intrinsic “safety catch” regulatory tripeptide  Journal Articles
• Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα  Journal Articles
• Mechanical Stretch-Induced Signal Transduction in Cultured Mesangial Cells  Journal Articles
• Mechanical stretch-induced RhoA activation is mediated by the RhoGEF Vav2 in mesangial cells  Journal Articles
• Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK  Journal Articles
• Mechanisms by Which Soluble Endothelial Cell Protein C Receptor Modulates Protein C and Activated Protein C Function  Journal Articles
• Mechanisms for Inhibition of the Generation of Thrombin Activity by Sulfated Polysaccharides^a  Journal Articles
• Mesangial cell signaling cascades in response to mechanical strain and glucose  Journal Articles
• Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity  Journal Articles
• Modulation of Human Airway Smooth Muscle Migration by Lipid Mediators and Th-2 Cytokines  Journal Articles
• Modulation of Monocyte Function by Activated Protein C, a Natural Anticoagulant  Journal Articles
• Modulation of the Enzymatic Activity of α-Thrombin by Polyanions: Consequences on Intrinsic Activation of Factor V and Factor VIII  Journal Articles
• Molecular Mechanism of the Enterococcal Aminoglycoside 6‘-N-Acetyltransferase‘:  Role of GNAT-Conserved Residues in the Chemistry of Antibiotic Inactivation  Journal Articles
• Molecular structural analysis of a novel and de‐novo mutation in the SERPINC1 gene associated with type 1 antithrombin deficiency  Journal Articles
• NMR Structures Reveal How Oxidation Inactivates Thrombomodulin  Journal Articles
• NO⁺but not NO radical relaxes airway smooth muscle via cGMP-independent release of internal Ca²⁺  Journal Articles
• NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway  Journal Articles
• Neuronal Cdc2-like kinase: from cell cycle to neuronal function  Journal Articles
• New isolate of Streptomyces sp. with novel thermoalkalotolerant cellulases  Journal Articles
• Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells  Journal Articles
• Nitric oxide modulates stretch activation of mitogen-activated protein kinases in mesangial cells  Journal Articles
• Nitrofuran‐Reducing Enzymes of Euglena*  Journal Articles
• Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations  Journal Articles
• O₂uptake kinetics, pyruvate dehydrogenase activity, and muscle deoxygenation in young and older adults during the transition to moderate-intensity exercise  Journal Articles
• On the ouabain-sensitive potassium activated p-nitrophenyl phosphatase activity of vascular muscle plasma membranes.  Journal Articles
• Optimization of a Fluorescence-based Lysozyme Activity Assay for Contact Lens Studies  Journal Articles
• Oxidative stress and antioxidant enzyme upregulation in SOD1‐G93A mouse skeletal muscle  Journal Articles
• Oxidative stress and metabolic responses to copper in freshwater- and seawater-acclimated killifish, Fundulus heteroclitus  Journal Articles
• PDH activation by dichloroacetate reduces TCA cycle intermediates at rest but not during exercise in humans  Journal Articles
• PDH-E1α Dephosphorylation and Activation in Human Skeletal Muscle During Exercise  Journal Articles
• PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells  Journal Articles
• PTEN inhibits BMI1 function independently of its phosphatase activity  Journal Articles
• Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts  Journal Articles
• Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells  Journal Articles
• Pancratistatin induces apoptosis and autophagy in metastatic prostate cancer cells  Journal Articles
• Patients with severe sepsis vary markedly in their ability to generate activated protein C  Journal Articles
• Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death  Journal Articles
• Pharmacological inhibition of forskolin-stimulated adenylate cyclase activity in rat brain by melatonin, its analogs, and diazepam  Journal Articles
• Phosphoester-transfer mechanism of an RNA-cleaving acidic deoxyribozyme revealed by radioactivity tracking and enzymatic digestion  Journal Articles
• Phosphorylation of PITSLRE p110 Isoforms Accompanies Their Processing by Caspases during Fas-mediated Cell Death  Journal Articles
• Plasmin accelerates platelet‐dependent prothrombinase formation without activating the platelets  Journal Articles
• Pleiotropic Action of AP-1 in v-Src-Transformed Cells  Journal Articles
• Prior heavy exercise elevates pyruvate dehydrogenase activity and speeds O₂ uptake kinetics during subsequent moderate‐intensity exercise in healthy young adults  Journal Articles
• Pro- and macroglycogenolysis during repeated exercise: roles of glycogen content and phosphorylase activation  Journal Articles
• Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7  Journal Articles
• Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation  Journal Articles
• Properties of potassium activatedp-nitrophenyl phosphatase of plasma membranes isolated from rat stomach muscle  Journal Articles
• Pyruvate dehydrogenase activation in inactive muscle during and after maximal exercise in men  Journal Articles
• Rapid upregulation of pyruvate dehydrogenase kinase activity in human skeletal muscle during prolonged exercise  Journal Articles
• Receptor-mediated protein kinase activation and the mechanism of transmembrane signaling in bacterial chemotaxis  Journal Articles
• Reconstitution of rabbit sarcoplasmic reticulum calcium ATPase in a series of phosphatidylcholines containing a saturated and an unsaturated chain: suggestion of an optimal lipid environment  Journal Articles
• Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M  Journal Articles
• Regulation of NADH/CoQ Oxidoreductase: Do Phosphorylation Events Affect Activity?  Journal Articles
• Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain  Journal Articles
• Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6.  Journal Articles
• Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis  Journal Articles
• Requirement of Lysine Residues Outside of the Proposed Pentasaccharide Binding Region for High Affinity Heparin Binding and Activation of Human Antithrombin III  Journal Articles
• Requirement of p38 stress-activated MAP kinase for cell death in the developing retina depends on the stage of cell differentiation  Journal Articles
• Rh proteins and NH4+-activated Na+-ATPase in the Magadi tilapia (Alcolapia grahami), a 100% ureotelic teleost fish  Journal Articles
• RhoA Activation in Mesangial Cells by Mechanical Strain Depends on Caveolae and Caveolin-1 Interaction  Journal Articles
• RhoA/Rho-Kinase Contribute to the Pathogenesis of Diabetic Renal Disease  Journal Articles
• Role of α-Helical Coiled-coil Interactions in Receptor Dimerization, Signaling, and Adaptation during Bacterial Chemotaxis  Journal Articles
• SIPL1 enhances the proliferation, attachment, and migration of CHO cells by inhibiting PTEN function  Journal Articles
• SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation.  Journal Articles
• STABILIZATION OF DIHYDROFOLATE REDUCTASE BY INHIBITORS IN VIVO AND IN VITRO*  Journal Articles
• Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis  Journal Articles
• Salicylate improves macrophage cholesterol homeostasis via activation of Ampk  Journal Articles
• Selenite Negatively Regulates Caspase-3 through a Redox Mechanism  Journal Articles
• Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells  Journal Articles
• Skeletal muscle metabolism is unaffected by DCA infusion and hyperoxia after onset of intense aerobic exercise  Journal Articles
• Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling  Journal Articles
• Soluble fibrin degradation products potentiate tissue plasminogen activator-induced fibrinogen proteolysis.  Journal Articles
• Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes  Journal Articles
• Stimulation of Na⁺, K⁺‐pump activity in skeletal muscle by methylxanthines: evidence and proposed mechanisms  Conferences
• Stretch-induced Raf-1 activation in mesangial cells requires actin cytoskeletal integrity  Journal Articles
• Structure Activity Studies on the Crinane Alkaloid Apoptosis-inducing Pharmacophore  Journal Articles
• Studies on Protein Subunits  Journal Articles
• Sublethal mechanisms of Pb and Zn toxicity to the purple sea urchin (Strongylocentrotus purpuratus) during early development  Journal Articles
• Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability  Journal Articles
• Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy.  Journal Articles
• Synergistic effects between FSH and 1,1-dichloro-2,2-bis(P-chlorophenyl)ethylene (P,P'-DDE) on human granulosa cell aromatase activity  Journal Articles
• Synthesis and Biological Activity of a Focused Library of Mitogen‐activated Protein Kinase Phosphatase Inhibitors  Journal Articles
• TGFβ-induced RhoA activation and fibronectin production in mesangial cells require caveolae  Journal Articles
• Telomere elongation in immortal human cells without detectable telomerase activity.  Journal Articles
• Tentative de localisation histochimique d'une ATPase-Na+-K+ au niveau de l'�pith�lium pseudobranchial des T�l�ost�ens  Journal Articles
• Thallous ion activation of p-nitrophenylphosphatase of rat myometrium plasma membrane  Journal Articles
• The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting  Journal Articles
• The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase  Journal Articles
• The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2  Journal Articles
• The Chirality of Phosphatidylserine and the Activation of Protein Kinase C  Journal Articles
• The Effects of Leptin on Airway Smooth Muscle Responses  Journal Articles
• The Human Cationic Peptide LL-37 Induces Activation of the Extracellular Signal-Regulated Kinase and p38 Kinase Pathways in Primary Human Monocytes  Journal Articles
• The Protein-Protein Interaction-Mediated Inactivation of PTEN  Journal Articles
• The Roles of Selected Arginine and Lysine Residues of TAFI (Pro-CPU) in Its Activation to TAFIa by the Thrombin-Thrombomodulin Complex  Journal Articles
• The Suppressor of Cytokine Signaling 3 Inhibits Leptin Activation of AMP-Kinase in Cultured Skeletal Muscle of Obese Humans  Journal Articles
• The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades.  Journal Articles
• The acute effects of differential dietary fatty acids on human skeletal muscle pyruvate dehydrogenase activity  Journal Articles
• The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning.  Journal Articles
• The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung  Journal Articles
• The decrease in phosphatidylinositol 4,5-bisphosphate in ADP-stimulated washed rabbit platelets is not primarily due to phospholipase C activation  Journal Articles
• The impact of the endothelial protein C receptor on thrombin generation and clot lysis  Journal Articles
• The inhibition of thrombin-dependent positive-feedback reactions is critical to the expression of the anticoagulant effect of heparin  Journal Articles
• The microbiota and the gut-brain axis: insights from the temporal and spatial mucosal alterations during colonisation of the germfree mouse intestine  Journal Articles
• The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms  Journal Articles
• The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus  Journal Articles
• The plasma concentration of activated protein C appears normal in patients with haemophilia  Journal Articles
• The proteolytic action of Arvin on human fibrinogen  Journal Articles
• The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis  Journal Articles
• The use of poly(ethylene oxide) for the efficient stabilization of entrapped α-chymotrypsin in silicone elastomers: A chemometric study  Journal Articles
• Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes  Journal Articles
• Thrombin Binds to Soluble Fibrin Degradation Products Where it Is Protected From Inhibition by Heparin-Antithrombin but Susceptible to Inactivation by Antithrombin-Independent Inhibitors  Journal Articles
• Thrombin Inhibition by Hirudin: How Hirudin Inhibits Thrombin  Journal Articles
• Thrombin activation rate constant: One-stage chromogenic assay for the extrinsic system  Journal Articles
• Thrombin and Antithrombotics  Journal Articles
• Thrombin-activable Fibrinolysis Inhibitor Attenuates (DD)E-mediated Stimulation of Plasminogen Activation by Reducing the Affinity of (DD)E for Tissue Plasminogen Activator  Journal Articles
• Thrombin-activatable fibrinolysis inhibitor is activated in vivo in a baboon model of Escherichia coli induced sepsis  Journal Articles
• Toxic effects of the herbicide Roundup in the guppy Poecilia vivipara acclimated to fresh water  Journal Articles
• Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis  Journal Articles
• Transient pseudothrombocytopenia associated with immune heparin-induced thrombocytopenia complicated by pulmonary embolism  Journal Articles
• Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia  Journal Articles
• Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages  Journal Articles
• Tyrosine Phosphorylation of Caspase-8 Abrogates Its Apoptotic Activity and Promotes Activation of c-Src  Journal Articles
• Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression  Journal Articles
• Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene  Journal Articles
• Zinc delays clot lysis by attenuating plasminogen activation and plasmin-mediated fibrin degradation  Journal Articles
• cAMP activation of PKA defines an ancient signaling mechanism  Journal Articles
• p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade  Journal Articles
• β‐adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling  Journal Articles