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AMP-activated protein kinase, fatty acid...
Journal article

AMP-activated protein kinase, fatty acid metabolism, and insulin sensitivity

Abstract

PURPOSE OF REVIEW: Insulin resistance is an important risk factor for metabolic diseases such as type 2 diabetes, cardiovascular disease and certain cancers. A common characteristic of strategies that improve insulin sensitivity involves the activation of the energy sensing enzyme of the cell, AMP-activated protein kinase (AMPK). The purpose of this review is to explore the mechanisms associated with AMPK activation to improve insulin …

Authors

Smith BK; Steinberg GR

Journal

Current Opinion in Clinical Nutrition & Metabolic Care, Vol. 20, No. 4, pp. 248–253

Publisher

Wolters Kluwer

Publication Date

July 2017

DOI

10.1097/mco.0000000000000380

ISSN

1363-1950