Journal article
Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene.
Abstract
We have previously reported the use of a recombinant nonreplicating adenovirus type 5, Ad5HCMVsp1 lacZ, expressing the lacZ gene under control of the human cytomegalovirus (HCMV) immediate early promoter to assess repair of a UV-damaged reporter gene in UV and heat shock (HS) treated cells. Heat shock and UV-enhanced reactivation (HSER and UVER) of beta-galactosidase (beta-gal) activity for UV-irradiated Ad5HCMVsp1 lacZ in normal human …
Authors
McKay BC; Francis MA; Rainbow AJ
Journal
Carcinogenesis, Vol. 18, No. 2, pp. 245–249
Publisher
Oxford University Press (OUP)
Publication Date
February 1, 1997
DOI
10.1093/carcin/18.2.245
ISSN
0143-3334