Mice, Transgenic Concept

subject area of

• In VivoMagnetic Resonance Imaging and Semiautomated Image Analysis Extend the Brain Phenotype forcdf/cdfMice  Academic Article
• Pseudomonas aeruginosaLasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator–IL-6–antimicrobial–repair pathway  Academic Article
• A Dietary Supplement Abolishes Age-Related Cognitive Decline in Transgenic Mice Expressing Elevated Free Radical Processes  Academic Article
• A Double Recombinant Adenovirus Expressing the Costimulatory Molecule B7-1 (Murine) and Human IL-2 Induces Complete Tumor Regression in a Murine Breast Adenocarcinoma Model  Academic Article
• A Lactobacillus rhamnosus Strain Induces a Heme Oxygenase Dependent Increase in Foxp3+ Regulatory T Cells  Academic Article
• A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells  Academic Article
• A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada  Academic Article
• A Study of the Purine Derivative AIT-082 in G93A SOD1 Transgenic Mice  Academic Article
• A Transgenic Mouse Model to Study Glucose Transporter 4myc Regulation in Skeletal Muscle  Academic Article
• A complex dietary supplement modulates nitrative stress in normal mice and in a new mouse model of nitrative stress and cognitive aging  Academic Article
• A huntingtin-mediated fast stress response halting endosomal trafficking is defective in Huntington's disease  Academic Article
• A lacZ transgenic mouse assay for the detection of mutations in follicular granulosa cells  Academic Article
• A multi‐ingredient dietary supplement abolishes large‐scale brain cell loss, improves sensory function, and prevents neuronal atrophy in aging mice  Academic Article
• A novel GFP reporter mouse revealsMustn1expression in adult regenerating skeletal muscle, activated satellite cells and differentiating myoblasts  Academic Article
• A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells  Academic Article
• A p75 tumor necrosis factor receptor-specific mutant of murine tumor necrosis factor α expressed from an adenovirus vector induces an antitumor response with reduced toxicity  Academic Article
• A transgenic mouse line harboring a smooth muscle alpha-actin promoter polyomavirus middle T antigen transgene develops an epithelial hyperplasia in the rectum and distal stomach.  Academic Article
• A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis  Academic Article
• AMPK as a Therapeutic Target for Treating Metabolic Diseases  Academic Article
• AMPK-Dependent Inhibitory Phosphorylation of ACC Is Not Essential for Maintaining Myocardial Fatty Acid Oxidation  Academic Article
• AMPK-independent pathways regulate skeletal muscle fatty acid oxidation  Academic Article
• AP‐2α is required after lens vesicle formation to maintain lens integrity  Academic Article
• Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology  Academic Article
• Abrogation of mesenchyme-specific TGF-β signaling results in lung malformation with prenatal pulmonary cysts in mice  Academic Article
• Acetylcholine-producing T cells in the intestine regulate antimicrobial peptide expression and microbial diversity  Academic Article
• Activated calcineurin ameliorates contraction-induced injury to skeletal muscles ofmdxdystrophic mice  Academic Article
• Activation of the Hedgehog Signaling Pathway in the Developing Lens Stimulates EctopicFoxE3Expression and Disruption in Fiber Cell Differentiation  Academic Article
• Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models  Academic Article
• Adenoviral vector-mediated GM-CSF gene transfer improves anti-mycobacterial immunity in mice – role of regulatory T cells  Academic Article
• Adenylyl Cyclase type 3, a marker of primary cilia, is reduced in primary cell culture and in lumbar spinal cord in situ in G93A SOD1 mice  Academic Article
• Aerobic training as an adjunctive therapy to enzyme replacement in Pompe disease  Academic Article
• An Intact Intermediate Filament Network Is Required for Collateral Sprouting of Small Diameter Nerve Fibers  Academic Article
• An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene  Academic Article
• An aptamer‐based magnetic resonance imaging contrast agent for detecting oligomeric amyloid‐β in the brain of an Alzheimer's disease mouse model  Academic Article
• An upstream region of the enoyl-coenzyme A hydratase/3-hydroxyacyl-coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice.  Academic Article
• Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection  Academic Article
• Ancient selection for derived alleles at a GDF5 enhancer influencing human growth and osteoarthritis risk  Academic Article
• Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin  Academic Article
• Antigen Presentation by Exosomes Released from Peptide-Pulsed Dendritic Cells Is not Suppressed by the Presence of Active CTL  Academic Article
• Antigen Specificity Acquisition of Adoptive CD4+ Regulatory T Cells via Acquired Peptide-MHC Class I Complexes  Academic Article
• Astrocytes Prevent Abnormal Neuronal Development in the Fragile X Mouse  Academic Article
• Autoimmune Manifestations in the 3xTg-AD Model of Alzheimer's Disease  Academic Article
• BL-7010 Demonstrates Specific Binding to Gliadin and Reduces Gluten-Associated Pathology in a Chronic Mouse Model of Gliadin Sensitivity  Academic Article
• BMP Receptor ALK3 Controls Collecting System Development  Academic Article
• Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax  Academic Article
• Beneficial effect of ginseng root in SOD-1 (G93A) transgenic mice  Academic Article
• Black Cohosh Increases Metastatic Mammary Cancer in Transgenic Mice Expressing c-erbB2  Academic Article
• CD11c+ antigen presenting cells from the alveolar space, lung parenchyma and spleen differ in their phenotype and capabilities to activate naïve and antigen-primed T cells  Academic Article
• CHIP Deficiency Decreases Longevity, with Accelerated Aging Phenotypes Accompanied by Altered Protein Quality Control  Academic Article
• Calcineurin-Aα activation enhances the structure and function of regenerating muscles after myotoxic injury  Academic Article
• Caloric Restriction Shortens Lifespan through an Increase in Lipid Peroxidation, Inflammation and Apoptosis in the G93A Mouse, an Animal Model of ALS  Academic Article
• Caloric restriction transiently improves motor performance but hastens clinical onset of disease in the Cu/Zn-superoxide dismutase mutant G93A mouse  Academic Article
• Carotid Body: New Stimuli and New Preparations – Invited Article  Academic Article
• Cellular and Molecular Regulation of Skeletal Muscle Side Population Cells  Academic Article
• Cellular and physiological roles of SR-BI, a lipoprotein receptor which mediates selective lipid uptake  Academic Article
• Ceramide Is Responsible for the Failure of Compensatory Nerve Sprouting in Apolipoprotein E Knock-Out Mice  Academic Article
• Cerebrolysin modulates pronerve growth factor/nerve growth factor ratio and ameliorates the cholinergic deficit in a transgenic model of Alzheimer's disease  Academic Article
• Characterization of a Mouse Model for Thrombomodulin Deficiency  Academic Article
• Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor Receptor  Academic Article
• Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis  Academic Article
• Characterization of the effects of exercise training on hematopoietic stem cell quantity and function  Academic Article
• Characterizing Complex Polysera Produced by Antigen-Specific Immunization through the Use of Affinity-Selected Mimotopes  Academic Article
• Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53  Academic Article
• Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology  Academic Article
• Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice  Academic Article
• Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle  Academic Article
• Ciliary Neurotrophic Factor Stimulates Muscle Glucose Uptake by a PI3-Kinase–Dependent Pathway That Is Impaired With Obesity  Academic Article
• Circuit Mechanisms Underlying Motor Memory Formation in the Cerebellum  Academic Article
• Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity  Academic Article
• Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer  Academic Article
• Combined Treatment of a Murine Breast Cancer Model with Type 5 Adenovirus Vectors Expressing Murine Angiostatin and IL-12: A Role for Combined Anti-Angiogenesis and Immunotherapy  Academic Article
• Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy  Academic Article
• Compromised genomic integrity impedes muscle growth after Atrx inactivation  Academic Article
• Conditional Deletion of AP-2α and AP-2β in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function  Academic Article
• Contraction-induced skeletal muscle FAT/CD36 trafficking and FA uptake is AMPK independent  Academic Article
• Control of Motoneuron Survival by Angiogenin  Academic Article
• Creatine supplementation and riluzole treatment provide similar beneficial effects in copper, zinc superoxide dismutase (G93A) transgenic mice  Academic Article
• Critical Negative Regulation of Type 1 T Cell Immunity and Immunopathology by Signaling Adaptor DAP12 during Intracellular Infection  Academic Article
• Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis  Academic Article
• Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL−/− mice: Support for a role for TDP-43 in the physiological response to neuronal injury  Academic Article
• Cytosolic localization of Fox proteins in motor neurons of G93A SOD1 mice  Academic Article
• De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors  Academic Article
• De novo pathogenic variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe axonal polyneuropathy  Academic Article
• Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease  Academic Article
• Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice  Academic Article
• Delivery of viral-vectored vaccines by B cells represents a novel strategy to accelerate CD8+ T-cell recall responses  Academic Article
• Demyelination in a transgenic mouse: A model for multiple sclerosis  Academic Article
• Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells  Academic Article
• Developmental and Lactational Exposure to Dieldrin Alters Mammary Tumorigenesis in Her2/neu Transgenic Mice  Academic Article
• Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration  Academic Article
• Dietary amelioration of locomotor, neurotransmitter and mitochondrial aging  Academic Article
• Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice  Academic Article
• Differentiation of bone marrow-derived cells into regenerated mesothelial cells in peritoneal remodeling using a peritoneal fibrosis mouse model  Academic Article
• Discovery of Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for Live-Cell and In Vivo Imaging  Academic Article
• Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling  Academic Article
• Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2  Academic Article
• ER Stress and Lipogenesis: A Slippery Slope toward Hepatic Steatosis  Academic Article
• Early Intervention with a Multi-Ingredient Dietary Supplement Improves Mood and Spatial Memory in a Triple Transgenic Mouse Model of Alzheimer’s Disease  Academic Article
• Ectopic Expression of AP-2α Transcription Factor in the Lens Disrupts Fiber Cell Differentiation  Academic Article
• Effect of covalent antithrombin-heparin complex on developmental mechanisms in the lung  Academic Article
• Effects of Creatine and Exercise on Skeletal Muscle of FRG1-Transgenic Mice  Academic Article
• Effects of Salt Loading on the Morphology of Astrocytes in the Ventral Glia Limitans of the Rat Supraoptic Nucleus  Academic Article
• Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis  Academic Article
• Electroporation Enables Plasmid Vaccines to Elicit CD8+ T Cell Responses in the Absence of CD4+ T Cells  Academic Article
• Elevated Blood Pressure in Transgenic Lipoatrophic Mice and Altered Vascular Function  Academic Article
• Elevated DNA damage in a mouse model of oxidative stress: impacts of ionizing radiation and a protective dietary supplement  Academic Article
• Embryonic and Neonatal Phenotyping of Genetically Engineered Mice  Academic Article
• Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt Activation  Academic Article
• Endothelial Nitric Oxide Synthase Promotes Bone Marrow Stromal Cell Migration to the Ischemic Myocardium via Upregulation of Stromal Cell-Derived Factor-1α    Academic Article
• Endothelial cell tumors develop in transgenic mice carrying polyoma virus middle T oncogene  Academic Article
• Energy-stress-mediated AMPK activation inhibits ferroptosis  Academic Article
• Enhanced Interleukin-2 Gene Transfer Immunotherapy of Breast Cancer by Coexpression of B7-1 and B7-2  Academic Article
• Eosinophil-derived IL-13 promotes emphysema  Academic Article
• Eosinophils and T Lymphocytes Possess Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis  Academic Article
• ErbB2 Is Required for Muscle Spindle and Myoblast Cell Survival  Academic Article
• Estradiol Promotes Growth and Angiogenesis in Polyoma Middle T Transgenic Mouse Mammary Tumor Explants  Academic Article
• Ethylenecarbodiimide-Fixed Donor Splenocyte Infusions Differentially Target Direct and Indirect Pathways of Allorecognition for Induction of Transplant Tolerance  Academic Article
• Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model  Academic Article
• Expression of Dual TCR on DO11.10 T Cells Allows for Ovalbumin-Induced Oral Tolerance to Prevent T Cell-Mediated Colitis Directed against Unrelated Enteric Bacterial Antigens  Academic Article
• Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3  Academic Article
• Factors influencing therapeutic efficacy and the host immune response to helper‐dependent adenoviral gene therapy in hemophilia A mice  Academic Article
• Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues  Academic Article
• Function of PEA3 Ets transcription factors in mammary gland development and oncogenesis.  Academic Article
• GLI3 Repressor Controls Nephron Number via Regulation of Wnt11 and Ret in Ureteric Tip Cells  Academic Article
• GM-CSF Transgene-Based Adjuvant Allows the Establishment of Protective Mucosal Immunity Following Vaccination with Inactivated Chlamydia trachomatis  Academic Article
• GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia  Academic Article
• Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer  Academic Article
• Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice  Academic Article
• Glycogen Synthase Kinase 3α Deficiency Attenuates Atherosclerosis and Hepatic Steatosis in High Fat Diet–Fed Low Density Lipoprotein Receptor–Deficient Mice  Academic Article
• Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation  Academic Article
• Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures  Academic Article
• Heparan sulfate: Antithrombotic or not?  Academic Article
• Hepatocyte Growth Factor and MET Support Mouse Enteric Nervous System Development, the Peristaltic Response, and Intestinal Epithelial Proliferation in Response to Injury  Academic Article
• High-Grade Glioma Formation Results from Postnatal Pten Loss or Mutant Epidermal Growth Factor Receptor Expression in a Transgenic Mouse Glioma Model  Academic Article
• Histological assessment of intermediate- and long-term creatine monohydrate supplementation in mice and rats  Academic Article
• Host-specific differences in the physiology of acid secretion related to prostaglandins may play a role in gastric inflammation and injury  Academic Article
• Hsp72 preserves muscle function and slows progression of severe muscular dystrophy  Academic Article
• Humanized mice are susceptible to Salmonella typhi infection  Academic Article
• Identification of T-lymphocytic leukemia–initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease  Academic Article
• Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein  Academic Article
• Immediate-early gene response to methamphetamine, haloperidol, and quinolinic acid is not impaired in Huntington's disease transgenic mice  Academic Article
• Immunoreactivity of the phosphorylated axonal neurofilament H subunit (pNF-H) in blood of ALS model rodents and ALS patients: evaluation of blood pNF-H as a potential ALS biomarker  Academic Article
• Impaired c-src activation and motility defects in PEA3-null fibroblasts  Academic Article
• In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer  Academic Article
• Increased Bacterial Translocation in Gluten-Sensitive Mice Is Independent of Small Intestinal Paracellular Permeability Defect  Academic Article
• Increased proliferation of hepatic periportal ductal progenitor cells contributes to persistent hypermetabolism after trauma  Academic Article
• Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity  Academic Article
• Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation  Academic Article
• Inhalation Tolerance Is Induced Selectively in Thoracic Lymph Nodes but Executed Pervasively at Distant Mucosal and Nonmucosal Tissues  Academic Article
• Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin  Academic Article
• Innate immunity in amyotrophic lateral sclerosis  Academic Article
• Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1  Academic Article
• Interferon-λ Mediates Oral Tolerance and Inhibits Antigen-Specific, T-Helper 2 Cell–Mediated Inflammation in Mouse Intestine  Academic Article
• Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression  Academic Article
• Interleukin-15 Modulates Adipose Tissue by Altering Mitochondrial Mass and Activity  Academic Article
• Interleukin-15 expression affects homeostasis and function of B cells through NK cell-derived interferon-γ  Academic Article
• Intracellular Accumulation of Detergent-Soluble Amyloidogenic Aβ Fragment of Alzheimer's Disease Precursor Protein in the Hippocampus of Aged Transgenic Mice  Academic Article
• Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors  Academic Article
• Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model.  Academic Article
• Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic leukemia  Academic Article
• Invariant NKT cells sustain specific B cell responses and memory  Academic Article
• Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells  Academic Article
• Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory development  Academic Article
• Larazotide acetate regulates epithelial tight junctions in vitro and in vivo  Academic Article
• Lens-Specific Expression of TGF-β Induces Anterior Subcapsular Cataract Formation in the Absence of Smad3  Academic Article
• Loss of Hepatocyte-Nuclear-Factor-4α Affects Colonic Ion Transport and Causes Chronic Inflammation Resembling Inflammatory Bowel Disease in Mice  Academic Article
• Loss of Wasl improves pancreatic cancer outcome  Academic Article
• MMP9 Differentially Regulates Proteins Involved in Actin Polymerization and Cell Migration during TGF-β-Induced EMT in the Lens  Academic Article
• Male Sexual Dysfunction in Mice Bearing Targeted Mutant Alleles of the PEA3 ets Gene  Academic Article
• Maternal Embryonic Leucine Zipper Kinase Is Upregulated and Required in Mammary Tumor-Initiating Cells In vivo  Academic Article
• Matrix Metalloproteinase-9–Null Mice Are Resistant to TGF-β–Induced Anterior Subcapsular Cataract Formation  Academic Article
• Melatonin Antioxidative Defense: Therapeutical Implications for Aging and Neurodegenerative Processes  Academic Article
• Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13  Academic Article
• Modulation of Hepatic Granulomatous Responses by Transgene Expression of DAP12 or TREM-1-Ig Molecules  Academic Article
• Molecular Cloning and Cell-Free Expression of Mouse Antithrombin III  Academic Article
• Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals  Academic Article
• Mouse phenogenomics, toolbox for functional annotation of human genome  Academic Article
• MpzR98C arrests Schwann cell development in a mouse model of early-onset Charcot–Marie–Tooth disease type 1B  Academic Article
• Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4  Academic Article
• Muscle satellite cell and atypical myogenic progenitor response following exercise  Academic Article
• Muscle-specific overexpression of IGF-I improves E-C coupling in skeletal muscle fibers from dystrophicmdxmice  Academic Article
• N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation  Academic Article
• NGF over-expression during development leads to permanent alterations in innervation in the spinal cord and in behavioural responses to sensory stimuli  Academic Article
• Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells  Academic Article
• Nerve growth factor promoter activity revealed in mice expressing enhanced green fluorescent protein  Academic Article
• Neurotrophic activity of proNGF in vivo  Academic Article
• Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence  Academic Article
• ORIGINAL ARTICLE: LPS-Induced Murine Abortions Require C5 but not C3, and are Prevented by Upregulating Expression of the CD200 Tolerance Signaling Molecule  Academic Article
• Obesity Resistance and Enhanced Insulin Sensitivity in Ahnak-/- Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy Expenditure  Academic Article
• Object recognition memory and BDNF expression are reduced in young TgCRND8 mice  Academic Article
• One Universal Common Endpoint in Mouse Models of Amyotrophic Lateral Sclerosis  Academic Article
• Osteopontin/secreted phosphoprotein-1 behaves as a molecular brake regulating the neuroinflammatory response to chronic viral infection  Academic Article
• Overexpression of Tumor Necrosis Factor-α Diminishes Pulmonary Fibrosis Induced by Bleomycin or Transforming Growth Factor-β  Academic Article
• Overexpression of insulin-like growth factor-II in transgenic mice is associated with pancreatic islet cell hyperplasia.  Academic Article
• Overexpression of nerve growth factor by murine smooth muscle cells: Role of the p75 neurotrophin receptor on sympathetic and sensory sprouting  Academic Article
• Oxidative stress and antioxidant enzyme upregulation in SOD1-G93A mouse skeletal muscle  Academic Article
• PEA3 is overexpressed in mouse metastatic mammary adenocarcinomas.  Academic Article
• PGC‐1α gene expression is down‐regulated by Akt‐mediated phosphorylation and nuclear exclusion of FoxO1 in insulin‐stimulated skeletal muscle  Academic Article
• Pathway Pathology  Academic Article
• Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression  Academic Article
• Plasma fibronectin supports hemostasis and regulates thrombosis  Academic Article
• Polymeric Binders Suppress Gliadin-Induced Toxicity in the Intestinal Epithelium  Academic Article
• Preneoplastic changes persist after IGF-IR downregulation and tumor regression  Academic Article
• Propagating factor IX-producing hepatocytes for haemophilia B therapy  Academic Article
• Proteolytic Cleavage of Ataxin-7 by Caspase-7 Modulates Cellular Toxicity and Transcriptional Dysregulation  Academic Article
• Purine receptor antagonist modulates serology and affective behaviors in lupus-prone mice: Evidence of autoimmune-induced pain?  Academic Article
• Quebec platelet disorder  Academic Article
• Rac1 and AMPK Account for the Majority of Muscle Glucose Uptake Stimulated by Ex Vivo Contraction but Not In Vivo Exercise  Academic Article
• Radiation-induced apoptosis in mouse lymphocytes is modified by a complex dietary supplement: the effect of genotype and gender  Academic Article
• Receptors for non-MHC ligands contribute to uterine natural killer cell activation during pregnancy in mice  Academic Article
• Recombinant Adenovirus Vaccines Can Successfully Elicit CD8+ T Cell Immunity under Conditions of Extreme Leukopenia  Academic Article
• Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity  Academic Article
• Reduced Tissue Levels of Noradrenaline Are Associated with Behavioral Phenotypes of the TgCRND8 Mouse Model of Alzheimer's Disease  Academic Article
• Relative Reduction of Endothelial Nitric-Oxide Synthase Expression and Transcription in Atherosclerosis-Prone Regions of the Mouse Aorta and in an in Vitro Model of Disturbed Flow  Academic Article
• Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis  Academic Article
• Respiratory macrophages regulate CD4 T memory responses to mucosal immunization with recombinant adenovirus-based vaccines  Academic Article
• Restoration of Vitamin C Synthesis in Transgenic Gulo^−/− Mice by Helper-Dependent Adenovirus-Based Expression of Gulonolactone Oxidase  Academic Article
• Restoration of innate immune activation accelerates Th1-cell priming and protection following pulmonary mycobacterial infection  Academic Article
• Reversibility and recurrence of IGF-IR-induced mammary tumors  Academic Article
• Role of CD200 expression in regulation of metastasis of EMT6 tumor cells in mice  Academic Article
• Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study  Academic Article
• SOX2, a Persistent Marker for Multipotential Neural Stem Cells Derived from Embryonic Stem Cells, the Embryo or the Adult  Academic Article
• Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop  Academic Article
• Sensitization to Gliadin Induces Moderate Enteropathy and Insulitis in Nonobese Diabetic-DQ8 Mice  Academic Article
• Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer  Academic Article
• Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice  Academic Article
• Shedding a new light on Huntington’s disease: how blood can both propagate and ameliorate disease pathology  Academic Article
• Single Unpurified Breast Tumor-Initiating Cells from Multiple Mouse Models Efficiently Elicit Tumors in Immune-Competent Hosts  Academic Article
• Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK  Academic Article
• Sleep of transgenic mice producing excess rat growth hormone  Academic Article
• Smad7 alters cell fate decisions of human hematopoietic repopulating cells  Academic Article
• Sodium channel distribution in axons of hypomyelinated and MAG null mutant mice  Academic Article
• Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract  Academic Article
• Specific CD45 isoforms differentially regulate T cell receptor signaling.  Academic Article
• Squalamine Restores the Function of the Enteric Nervous System in Mouse Models of Parkinson’s Disease  Academic Article
• Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis  Academic Article
• Stimulatory and inhibitory signaling molecules that regulate renal branching morphogenesis  Academic Article
• Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin  Academic Article
• Stromal β-catenin overexpression contributes to the pathogenesis of renal dysplasia  Academic Article
• Suppression of NK and CD8+ T cells reduces astrogliosis but accelerates cerebellar dysfunction and shortens life span in a mouse model of Sandhoff disease  Academic Article
• TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia  Academic Article
• TIM-4 Expressed by Mucosal Dendritic Cells Plays a Critical Role in Food Antigen–Specific Th2 Differentiation and Intestinal Allergy  Academic Article
• Targeted Expression of Human CD1d in Transgenic Mice Reveals Independent Roles for Thymocytes and Thymic APCs in Positive and Negative Selection of Vα14i NKT Cells  Academic Article
• Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction  Academic Article
• Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease  Academic Article
• Telomerase activity in normal and malignant murine tissues.  Academic Article
• The AIDS Disease of CD4C/HIV Transgenic Mice Shows Impaired Germinal Centers and Autoantibodies and Develops in the Absence of IFN-γ and IL-6  Academic Article
• The Absence or Overexpression of IL-15 Drastically Alters Breast Cancer Metastasis via Effects on NK Cells, CD4 T Cells, and Macrophages  Academic Article
• The Lectin-like Domain of Thrombomodulin Confers Protection from Neutrophil-mediated Tissue Damage by Suppressing Adhesion Molecule Expression via Nuclear Factor κB and Mitogen-activated Protein Kinase Pathways  Academic Article
• The POZ-ZF Transcription Factor Kaiso (ZBTB33) Induces Inflammation and Progenitor Cell Differentiation in the Murine Intestine  Academic Article
• The Pathophysiology of the Peritoneal Membrane  Academic Article
• The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation  Academic Article
• The breast tumor microenvironment alters the phenotype and function of natural killer cells  Academic Article
• The function of IGF-IR in NNK-mediated lung tumorigenesis  Academic Article
• The gene associated with trichorhinophalangeal syndrome in humans is overexpressed in breast cancer  Academic Article
• The human SCGB2A2 (Mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not in normal nonmammary cells  Academic Article
• The pea3 subfamily ets genes are required for HER2/Neu-mediated mammary oncogenesis  Academic Article
• The role of the high-density lipoprotein receptor SR-BI in cholesterol metabolism  Academic Article
• The role of the type I insulin-like growth factor receptor (IGF-IR) in glomerular integrity  Academic Article
• The serine protease inhibitor neuroserpin is required for normal synaptic plasticity and regulates learning and social behavior  Academic Article
• The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism  Academic Article
• Thrombus stability explains the factor V Leiden paradox: a mouse model  Academic Article
• Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection.  Academic Article
• Tissue Factor and Thrombosis Models  Academic Article
• Tissue factor microparticles and haemophilia  Academic Article
• Tissue specificity of oncogene action: endothelial cell tumours in polyoma middle T transgenic mice.  Academic Article
• Tissue- and site-specific DNA recombination in transgenic mice.  Academic Article
• Toxicogenomic Analysis of Mainstream Tobacco Smoke-Exposed Mice Reveals Repression of Plasminogen Activator Inhibitor-1 Gene in Heart  Academic Article
• Transgene-induced production of IL-4 alters the development and collagen expression of T helper cell 1-type pulmonary granulomas.  Academic Article
• Transgenic mice expressing the βAPP695SWE mutation: effects on exploratory activity, anxiety, and motor coordination  Academic Article
• Transgenic mice over-expressing substance P exhibit allodynia and hyperalgesia which are reversed by substance P and N-methyl-d-aspartate receptor antagonists  Academic Article
• Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation  Academic Article
• Transplants of neurosphere cell suspensions from aged mice are functional in the mouse model of Parkinson's  Academic Article
• Treatment of hemophilia B in mice with nonautologous somatic gene therapeutics  Academic Article
• Trophic and proliferative effects of Shh on motor neurons in embryonic spinal cord culture from wildtype and G93A SOD1 mice  Academic Article
• Tumour therapy in mice using adenovirus vectors expressing human TNFa.  Academic Article
• Type I Insulin-like Growth Factor Receptor Induces Pulmonary Tumorigenesis  Academic Article
• Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production  Academic Article
• USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation  Academic Article
• Update on pathways regulating the activation of uterine Natural Killer cells, their interactions with decidual spiral arteries and homing of their precursors to the uterus  Academic Article
• Upregulation of an opioid-mediated antinociceptive mechanism in transgenic mice over-expressing substance P in the spinal cord  Academic Article
• Uterine natural killer cells: insights into their cellular and molecular biology from mouse modelling  Academic Article
• Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice  Academic Article