Journal article
Function of PEA3 Ets Transcription Factors in Mammary Gland Development and Oncogenesis
Abstract
The Ets gene families of mice and man currently comprise 27 genes that encode sequence-specific transcription factors. Ets proteins share an ∼85 amino acid structurally conserved ETS DNA binding domain. Genetic analyses in model organisms suggest roles for Ets proteins in embryonic development and various adult physiological processes. Chromosomal translocations involving several ETS genes are associated with Ewing's sarcomas and leukemias, …
Authors
Kurpios NA; Sabolic NA; Shepherd TG; Fidalgo GM; Hassell JA
Journal
Journal of Mammary Gland Biology and Neoplasia, Vol. 8, No. 2, pp. 177–190
Publisher
Springer Nature
Publication Date
April 2003
DOI
10.1023/a:1025948823955
ISSN
1083-3021