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Radiation-induced apoptosis in mouse lymphocytes...
Journal article

Radiation-induced apoptosis in mouse lymphocytes is modified by a complex dietary supplement: the effect of genotype and gender

Abstract

This study examined whether radiation sensitivity measured by lymphocyte apoptosis could be ameliorated by a complex anti-oxidant/anti-ageing dietary supplement. We also examined lymphocytes from both genders of normal (Nr) mice as well as transgenic growth hormone (Tg) mice that express strongly elevated reactive oxygen species processes and a progeroid syndrome of accelerated ageing. We introduce Tg mice as a potentially valuable new model to …

Authors

Lemon JA; Rollo CD; McFarlane NM; Boreham DR

Journal

Mutagenesis, Vol. 23, No. 6, pp. 465–472

Publisher

Oxford University Press (OUP)

Publication Date

November 2008

DOI

10.1093/mutage/gen038

ISSN

0267-8357