Journal article
AMPK as a Therapeutic Target for Treating Metabolic Diseases
Abstract
The AMP-activated protein kinase (AMPK) is a central regulator of multiple metabolic pathways and may have therapeutic importance for treating obesity, insulin resistance, type 2 diabetes (T2D), non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease (CVD). Given the ubiquitous expression of AMPK, it has been a challenge to evaluate which tissue types may be most beneficially poised for mediating the positive metabolic effects of …
Authors
Day EA; Ford RJ; Steinberg GR
Journal
Trends in Endocrinology and Metabolism, Vol. 28, No. 8, pp. 545–560
Publisher
Elsevier
Publication Date
8 2017
DOI
10.1016/j.tem.2017.05.004
ISSN
1043-2760