Medicinal & Biomolecular Chemistry

subject area of

1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets Academic Article
1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story so Far And Perspectives (Part 1): Action in Ion Channels and GPCRs Academic Article
2-[F-18] FLUORO-L-DOPA Conference Paper
4-Aryl-3-(hydroxyalkyl)quinolin-2-ones: Novel Maxi-K Channel Opening Relaxants of Corporal Smooth Muscle Targeted for Erectile Dysfunction Academic Article
A 2.13 Å Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region Academic Article
A Bone-Seeking trans-Cyclooctene for Pretargeting and Bioorthogonal Chemistry: A Proof of Concept Study Using 99mTc- and 177Lu-Labeled Tetrazines Academic Article
A F-18 Labeling Strategy for Near Infrared Fluorophores. Multi-Modal Probes for Reactive Oxygen Species Conference Paper
A FAST Pattern Matching Algorithm Academic Article
A High-Throughput Screen of the GTPase Activity of Escherichia coli EngA to Find an Inhibitor of Bacterial Ribosome Biogenesis Academic Article
A NEW STRATEGY FOR LABELING BIOMOLECULES THAT CONTAIN DISULFIDE BONDS WITH RHENIUM AND TECHNETIUM Conference Paper
A NEW STRATEGY FOR THE PREPARATION AND PURIFICATION OF TC-BASED RADIOPHARMACEUTICALS Conference Paper
A New Generation of M(I) Chelates for Correlating in vitro and in vivo Imaging Conference Paper
A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin Academic Article
A New Strategy for Labeling Unreactive Peptides and Proteins with N-Succinimidyl 4-[F-18]Fluorobenzoate ([F-18]SFB) using water-in-oil microemulsions Conference Paper
A Refined Model for the Somatostatin Pharmacophore: Conformational Analysis of Lanthionine−Sandostatin Analogs Academic Article
A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image Analysis Academic Article
A cell-based approach to characterize antimicrobial compounds through kinetic dose response Academic Article
A hybrid solid-fluorous phase radioiodination and purification platform Academic Article
A macrophage-stimulating compound from a screen of microbial natural products Academic Article
A synthesis of 3-deoxydihydrolycoricidine: Refinement of a structurally minimum pancratistatin pharmacophore Academic Article
A tribute to Leo C Vining Academic Article
ACHIEVEING HIGH (APPARENT) SPECIFIC ACTIVITY FORMULATIONS USING FLUOROUS-PHASE CHEMISTRY Conference Paper
AROMATIC RADIOFLUORINATION WITH [F-18] F2 IN ANHYDROUS HYDROGEN-FLUORIDE Conference Paper
Actions of two dopamine derivatives at adreno- and cholinoceptors Academic Article
Alginate as an auxiliary bacterial membrane: binding of membrane-active peptides by polysaccharides Academic Article
Alginate as an auxiliary bacterial membrane: binding of membrane-active peptides by polysaccharides* Academic Article
Allosteric Modulation of the Dopamine D2 Receptor by Pro-Leu-Gly-NH2 Peptidomimetics Constrained in Either a Polyproline II Helix or a Type II β-Turn Conformation Academic Article
Allosteric Modulation of the Dopamine Receptor by Conformationally Constrained Type VI β-Turn Peptidomimetics of Pro-Leu-Gly-NH2 Academic Article
Allosteric Sensing of Fatty Acid Binding by NMR: Application to Human Serum Albumin Academic Article
Analog binding to melatonin receptors in chick brain: Effects of GTP and prazosin Academic Article
Antagonists of the Calcium Receptor I. Amino Alcohol-Based Parathyroid Hormone Secretagogues Academic Article
Anti-mesothelioma mechanism of action studies of a complex Cynara scolymus fraction using in silico target prediction and gene expression profiling Conference Paper
Antiallergic and antihistaminic effect of two extracts ofCapparis spinosa L. flowering buds Academic Article
Antibacterial metabolites from Australian macrofungi from the genus Cortinarius Conference Paper
Antimitotic activity of structurally simplified biaryl analogs of the anticancer agents colchicine and combretastatin A4 Academic Article
Antimitotic and cell growth inhibitory properties of combretastatin A-4-like ethers Academic Article
Antineoplastic Agents. 362. Isolation and X-ray Crystal Structure of Dibromophakellstatin from the Indian Ocean Sponge Phakellia mauritiana Academic Article
Antineoplastic Agents. 380. Isolation and X-ray Crystal Structure Determination of Isoaaptamine from the Republic of Singapore Hymeniacidon sp. and Conversion to the Phosphate Prodrug Hystatin 1 Academic Article
Apixaban Academic Article
Apixaban (vol 33, pg 293, 2008) Academic Article
Apocynum venetum leaf aqueous extract inhibits voltage-gated sodium channels of mouse neuroblastoma N2A cells Academic Article
Apocynum venetum leaf extract, an antihypertensive herb, inhibits rat aortic contraction induced by angiotensin II: A nitric oxide and superoxide connection Academic Article
Ascaridole-less infusions of Chenopodium ambrosioides contain a nematocide(s) that is(are) not toxic to mammalian smooth muscle Academic Article
Assay and Drug Development Technologies Journal
Assessing the potential of using the Mo-100(p,2n)Tc-99m transformation as a means of producing Curie-quantities of Tc-99m on existing cyclotron infrastructure Conference Paper
BAY 43-9006: Early Clinical Data in Patients with Advanced Solid Malignancies Academic Article
Bacterial proteases, untapped antimicrobial drug targets Academic Article
Bicyclic thiazolidine lactam peptidomimetics of the dopamine receptor modulating peptide Pro-Leu-Gly-NH2 Academic Article
Bioorganic and Medicinal Chemistry Journal
Bioorganic and Medicinal Chemistry Letters Journal
Biosynthesis of Anosmine: Incorporation of the Intact Six-Carbon Chain of Lysine and of Pipecolic Acid Academic Article
Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide β-lactone Academic Article
Biosynthesis of the alkaloids related to norlaudanosoline Academic Article
Biotransformation of anticancer drugs by human and environmental microbiomes Conference Paper
CARBORANE DERIVATIVES FOR TARGETING Tc-99m TO NEURORECEPTORS Conference Paper
Centipeda cunninghamii, an australian traditional medicinal plant Conference Paper
ChemMedChem Journal
Chemical composition and biological activity of the essential oils from native Australian Callitris species Conference Paper
Chemical variation from the neoantimycin depsipeptide assembly line Academic Article
Chemistry of Natural Compounds Khimiya Prirodnykh Soedinenii Journal
Christopher Walsh: Pioneer and innovator in antibiotic and natural product chemical biology Book
Cite and oversight Academic Article
Comparative pharmacological study of hydroethanol extracts ofPassiflora alata andPassiflora edulis leaves Academic Article
Complementary and Alternative Medicine Use in Juvenile Idiopathic Arthritis: A Systematic Review of Prevalence and Evidence Academic Article
Consideration of Cytokines as Therapeutics Agents or Targets Academic Article
Correction to Preparation, Characterization, and Screening of a High Affinity Organometallic Probe for α-Adrenergic Receptors Academic Article
Critical role for drug delivery in the development of new ophthalmic treatments Academic Article
Current Drug Discovery Technologies Journal
Current Medicinal Chemistry Journal
Current Opinion in Drug Discovery and Development Journal
Current Pharmaceutical Design Journal
Current Signal Transduction Therapy Journal
Cytokine Therapeutics for Asthma: An Appraisal of Current Evidence and Future Prospects Academic Article
Cytokines - Preface Academic Article
Cytokines - Preface Academic Article
Cytokines - Preface Academic Article
DIRECT FLUORINATION OF MELATONIN AND 5-HYDROXY-L-TRYPTOPHAN WITH [F-18] F2 Conference Paper
DISCOVERY AND EVALUATION OF A POTENTIAL MOLECULAR IMAGING AGENT FOR CATHEPSIN B Conference Paper
Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA Academic Article
Deletion sequences of salmon calcitonin that retain the essential biological and conformational features of the intact molecule Academic Article
Design and Synthesis of Photoaffinity-Labeling Ligands of the l-Prolyl-l-leucylglycinamide Binding Site Involved in the Allosteric Modulation of the Dopamine Receptor Academic Article
Design and function of a conformationally restricted analog of the influenza virus fusion peptide Academic Article
Design and synthesis of [ 125 I]Pyricoxib: A novel 125 I-labeled cyclooxygenase-2 (COX-2) inhibitors Academic Article
Design, Synthesis, X-ray Analysis, and Dopamine Receptor-Modulating Activity of Mimics of the "C5" Hydrogen-Bonded Conformation in the Peptidomimetic 2-Oxo-3(R)-[(2(S)-pyrrolidinylcarbonyl)amino]-1-pyrrolidineacetamide Academic Article
Design, Synthesis, and Dopamine Receptor Modulating Activity of Diketopiperazine Peptidomimetics of l-Prolyl-l-leucylglycinamide Academic Article
Design, Synthesis, and Dopamine Receptor Modulating Activity of Spiro Bicyclic Peptidomimetics of l-Prolyl-l-leucyl-glycinamide Academic Article
Designing analogs of ticlopidine, a wall teichoic acid inhibitor, to avoid formation of its oxidative metabolites Academic Article
Deterioration of storage phosphor screens with use Academic Article
Determination of Productive Conformation of Acetylcholinesterase Substrates Using Molecular Mechanics Academic Article
Determination of the Fatty Acid Composition of Amygdalus scoparia Kernels from Iran Using Gas Chromatography-Mass Spectrometry Academic Article
Determining the mode of action of bioactive compounds Academic Article
Development of tag-free photoprobes for studies aimed at identifying the target of novel Group A Streptococcus antivirulence agents Academic Article
Developments in mitogen-induced extracellular kinase 1 inhibitors and their use in the treatment of disease Academic Article
Direct Factor Xa and direct thrombin inhibitors: a clinical trial update. Academic Article
Direct fluorination of melatonin and 5-hydroxy-L-tryptophan with [¹⁸F]F2 Academic Article
Discovery of a new class of cinnamyl-triazole as potent and selective inhibitors of aromatase (cytochrome P450 19A1) Academic Article
Discovery of a novel class of aldol-derived 1,2,3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase) Academic Article
Discovery of potent antiviral (HSV-1) quinazolinones and initial structure-activity relationship studies Academic Article
Discovery of the Apoptosis-Inducing Activity and High Accumulation of the Butenolides, Menisdaurilide and Aquilegiolide, in Dicentra spectabilis Academic Article
Discovery, Synthesis and Antimalarial Evaluation of Natural Product-based Polyamines Conference Paper
Do Insecticides have Adverse Effects on Reproduction Academic Article
Do the metabolites of 6-[F-18]fluoro-L-dopa and of [F-18]fluoro-meta-L-tyrosine contribute to the F-18 accumulation in the human brain? Conference Paper
Docking flexible ligands in proteins with a solvent exposure- and distance-dependent dielectric function Academic Article
Dopamine receptor modulation by Pro-Leu-Gly-NH2 analogs possessing cyclic amino acid residues at the C-terminal position Academic Article
Dopamine receptor modulation by a highly rigid spiro bicyclic peptidomimetic of Pro-Leu-Gly-NH2 Academic Article
Dopamine receptor modulation by conformationally constrained analogs of Pro-Leu-Gly-NH2 Academic Article
Drug Discovery Today Journal
Drug evaluation: AP-23573--an mTOR inhibitor for the treatment of cancer. Academic Article
Drug evaluation: E-5564. Academic Article
Drugs of the Future Journal
Effect of a tobacco-related nitrosamine on intercellular communication in human urothelial cells: a possible factor in smoking-related bladder carcinogenesis. Academic Article
Efficient Synthesis of Cannabigerol, Grifolin, and Piperogalin via Alumina-Promoted Allylation Academic Article
Emulsion reactors; A new platform for the synthesis of metal-based molecularimaging agents Conference Paper
Enzymatic synthesis of (−)-6-[18F]-fluoronorepinephrine from 6-[18F]-fluorodopamine by dopamine β-hydroxylase Academic Article
Erratum to “Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA” [Bioorg. Med. Chem. Lett. 23 (2013) 2426–2431] Academic Article
European Journal of Medicinal Chemistry Journal
Evaluation of synthetic coumarins for antiausterity cytotoxicity against pancreatic cancers Academic Article
Evidences for direct action of diethylcarbamazine on the Brugia malayi adult worm: immunoreactivity pattern of adult worms exposed to DEC in vitro and in vivo. Academic Article
Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds Academic Article
Experimental Screening of Dihydrofolate Reductase Yields a “Test Set” of 50,000 Small Molecules for a Computational Data-Mining and Docking Competition Academic Article
Expert Opinion on Therapeutic Patents Journal
Exploring the awareness of research among registered massage therapists in Ontario Academic Article
Extracellular Signal-Regulated Kinases Modulate DNA Damage Response - A Contributing Factor to Using MEK Inhibitors in Cancer Therapy Academic Article
Extremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIA Academic Article
F-18 LABELED XENON DIFLUORIDE Conference Paper
FLUORINE-18 LABELLED AROMATIC AMINO ACIDS FOR TUMOR IMAGING USING PET Conference Paper
Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion Academic Article
First JA Medal goes to a paper on decalpenic acid Academic Article
Functional annotation of putative aminoglycoside antibiotic modifying proteins in Mycobacterium tuberculosis H37Rv Academic Article
Future Medicinal Chemistry Journal
Garlic for hypertension: A systematic review and meta-analysis of randomized controlled trials Academic Article
Gene Therapy, A Targeted Treatment for Diabetic Nephropathy Academic Article
Gene Vectors for Cytokine Expression In Vivo Academic Article
Ginkgo biloba extract for essential hypertension: A systemic review Academic Article
Global Gastrointestinal Safety Profile of Etoricoxib and Lumiracoxib Academic Article
Glycopeptide antibiotic biosynthesis Academic Article
Growth hormone-releasing factor analogs with hydrophobic residues at position 19. Effects on growth hormone releasing activity in vitro and in vivo, stability in blood plasma in vitro, and secondary structure Academic Article
High throughput screening identifies novel inhibitors of Escherichia coli dihydrofolate reductase that are competitive with dihydrofolate Academic Article
Human Cytochrome P450 Liability Studies of trans-Dihydronarciclasine: A Readily Available, Potent, and Selective Cancer Cell Growth Inhibitor Academic Article
Hydrophobic Interactions in Complexes of Antimicrobial Peptides with Bacterial Polysaccharides Academic Article
IDrugs : the investigational drugs journal Journal
ISO-STRUCTURAL FLUORESCENT AND Tc-99m PROBES FOR LABELING BIOMOLECULES Conference Paper
Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer Academic Article
Identification of Small Molecule Chemical Inhibitors of the Collagen-Specific Chaperone Hsp47 Academic Article
Identification of amidoheteroaryls as potent inhibitors of mutant (V600E) B-Raf kinase with in vivo activity Academic Article
Identification of common features within massage therapists’ professional identity Academic Article
Ilodecakin. Schering-Plough Corp. Academic Article
Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry Journal
Impact of 5-HT3 receptor antagonists on peripheral and central diseases Academic Article
Improved radiosynthesis and preliminary in vivo evaluation of the 11C-labeled tetrazine [11C]AE-1 for pretargeted PET imaging Academic Article
In Vitro Screening for Drug Repositioning Academic Article
In vitro biomass of Salvia corrugata: chemical analysis and evaluation of antimicrobial activity Conference Paper
In vitro evaluation of human cytochrome P450 and P-glycoprotein-mediated metabolism of some phytochemicals in extracts and formulations of African potato Academic Article
Incorporation of an inducible nucleotide analog into DNA by DNA polymerases Academic Article
Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition Academic Article
Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1 Academic Article
Informatic search for natural products (iSNAP) - A dereplication and discovery tool Conference Paper
Inhibition of the ANT(2″)-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones Academic Article
Inhibitors of Bacterial Cystathionine β-Lyase: Leads for New Antimicrobial Agents and Probes of Enzyme Structure and Function Academic Article
Intedanib, a triple kinase inhibitor of VEGFR, FGFR and PDGFR for the treatment of cancer and idiopathic pulmonary fibrosis. Academic Article
Integrating Complementary and Alternative Medicine With Primary Health Care Through Public Health To Improve Chronic Disease Management Academic Article
Interaction of Calcium Channel Antagonists with Calcium: Structural Studies on Nicardipine and Its Ca2+ Complex Academic Article
Interaction of calcium channel antagonists with calcium: spectroscopic and modeling studies on diltiazem and its Ca2+ complex Academic Article
Interaction of calcium channel antagonists with calcium: structural studies on verapamil and its Ca2+ complex Academic Article
Interaction of gonadotropin-releasing hormone and its agonist analogs with Ca2+ in a nonpolar milieu. Correlation with biopotencies Academic Article
Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase) Academic Article
Isolation and Synthesis of Veranamine, an Antidepressant Lead from the Marine Sponge Verongula rigida Academic Article
Isolation of Novel Cytotoxic Compounds from a Bangladeshi Medicinal Plant Acrostichum aureum Conference Paper
Isolation of flavonoids from apple peel using novel graphene oxide cotton fiber Academic Article
Isolation, Synthesis, and Semisynthesis of Amaryllidaceae Constituents from Narcissus and Galanthus sp.: De Novo Total Synthesis of 2-epi-Narciclasine Academic Article
Isotopic labelling in mass spectrometry as a tool for studying reaction mechanisms of ion dissociations Academic Article
Japanese Journal of Antibiotics Journal of Antibiotics Journal
Journal of Biomolecular Screening Journal
Journal of Chemical Information and Computer Sciences Journal of Chemical Information and Modeling Journal
Journal of Complementary and Integrative Medicine Journal
Journal of Computer-Aided Molecular Design Perspectives in Drug Discovery and Design Journal
Journal of Ethnopharmacology Journal
Journal of Labelled Compounds and Radiopharmaceuticals Journal
Journal of Medicinal Chemistry Journal of Medicinal and Pharmaceutical Chemistry Journal
Journal of Natural Products Journal
Journal of Peptide Research Peptide Research Chemical Biology and Drug Design Journal
L-prolyl-L-leucyl-glycinamide (PLG) and its analogs: Clinical implications in extrapyramidal motor disorders and depression Academic Article
Lanthionine−Somatostatin Analogs: Synthesis, Characterization, Biological Activity, and Enzymatic Stability Studies Academic Article
Left Ventricular Non-compaction: From Recognition to Treatment Academic Article
Ligands of Diltiazem Binding Site: An Overview of Some Chemotypes Academic Article
Literature Search and Review Academic Article
Macplocimine A, a new 18-membered macrolide isolated from the filamentous sulfur bacteria Thioploca sp. Academic Article
Marine Drugs Journal
Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist Academic Article
Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators Academic Article
Medicinal Chemistry Research Journal
Medicinal Research Reviews Journal
Message from the editors Academic Article
Mini-Reviews in Medicinal Chemistry Journal
Modifier Gene Studies to Identify New Therapeutic Targets in Cystic Fibrosis Academic Article
Modulation of Salmonella gene expression by subinhibitory concentrations of quinolones Academic Article
Molecular Dynamics of Fibrinogen Adsorption onto Graphene, but Not onto Poly(ethylene glycol) Surface, Increases Exposure of Recognition Sites That Trigger Immune Response Academic Article
Molecular Mechanism of Action and Selectivity of Sodium Ch annel Blocker Insecticides Academic Article
N-demethylation of cyamemazine via non-classical Polonovski reaction and its conjugation to bovine serum albumin Academic Article
Natural Product Research Natural Product Letters Journal
New Anticoagulants for the Prevention of Thromboembolism Academic Article
New phenolic inhibitors of yeast homoserine dehydrogenase Academic Article
Novel HldE-K Inhibitors Leading to Attenuated Gram Negative Bacterial Virulence Academic Article
Oncology Research Anti-Cancer Drug Design Journal
One-pot, multicomponent synthesis of 2,3-disubstituted quinazolin-ones with potent and selective activity against Toxoplasma gondii Academic Article
Opinion: Direct-to-consumer advertising of prescription medicines: a counter argument Academic Article
Ovarian Toxicity of Environmental Toxicants Academic Article
Pancratistatin Selectively Induces Apoptosis in Cancer Cells and Reduces Growth of Colon Xenografts Conference Paper
Pharmaceutical Biology Journal
Pharmacologic Properties of the New Oral Anticoagulants: A Clinician-oriented Review with a Focus on Perioperative Management Academic Article
Pharmacological Treatment of Hypertension in Pregnancy Academic Article
Pharmacology and Clinical Potential of Direct Thrombin Inhibitors Academic Article
Phenylalkylamines in calcium channels: computational analysis of experimental structures Academic Article
Phototoxic Furanoquinolines of the Rutaceae Academic Article
Phytomedicine Journal
Phytotherapy Research Journal
Planta Medica Journal
Polyphenolic natural products and natural product–inspired steroidal mimics as aromatase inhibitors Academic Article
Potent and selective inhibition of human cytochrome P450 3A4 by seco-pancratistatin structural analogs Academic Article
Potential Therapeutic Effects of Exogenous Ketone Supplementation for Type 2 Diabetes: A Review Academic Article
Preparation and Evaluation of Carborane Analogues of Tamoxifen Academic Article
Preparation and Evaluation of Fluorine-18-Labeled Insulin as a Molecular Imaging Probe for Studying Insulin Receptor Expression in Tumors Academic Article
Preparation and Evaluation of Halogenated and Metallated Cathepsin B Inhibitors as Molecular Imaging Agents Conference Paper
Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That Target Prostate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy Academic Article
Preparation and evaluation of reagents for tagging amino and thiol groups with fluorous stannanes. A convenient method for producing radioiodinated compounds in high effective specific activity Academic Article
Preparation of labelled 2-methoxy-3-alkylpyrazines: synthesis and characterization of deuterated 2-methoxy-3-isopropylyrazine and 2-methoxy-3-isobutylpyrazine Academic Article
Preparation of technetium-99m bifunctional chelate complexes using a microfluidic reactor: a comparative study with conventional and microwave labeling methods Academic Article
Preparation, Characterization, and Screening of a High Affinity Organometallic Probe for α-Adrenergic Receptors Academic Article
Production of new polyene antibiotics by Streptomyces cellulosae after addition of ethyl(Z)-16-phenylhexadec-9-enoate. Academic Article
Proteasome-mediated proteostasis: Novel medicinal and pharmacological strategies for diseases Academic Article
Pseudomonas aeruginosa: targeting cell-wall metabolism for new antibacterial discovery and development Academic Article
QSAR and Combinatorial Science Quantitative Structure-Activity Relationships Molecular Informatics Journal
Quantum Mechanics/Molecular Mechanics Strategies for Docking Pose Refinement: Distinguishing between Binders and Decoys in Cytochrome c Peroxidase Academic Article
RADIOFLUORINATION OF L-THREO-3-(3,4-DIHYDROXYPHENYL)SERINE: SYNTHESIS OF POTENTIAL F-18 LABELLED PET TRACERS FOR NOREPINEPHRINE Conference Paper
RADIOFLUORINATION WITH XENON DIFLUORIDE - L-6[F-18]FLUORO-DOPA Conference Paper
REGIO- AND STEREOSELECTIVE ELECTROPHILIC FLUORINATION OF 3,4,6-TRI-O-ACETYL-D-GLUCAL (TAG) IN ACIDIC MEDIUM Conference Paper
Radiosensitization of Colon Cancer Cell Lines by Docetaxel: Mechanisms of Action Academic Article
Rank Ordering Plate Data Facilitates Data Visualization and Normalization in High-Throughput Screening Academic Article
Re-evaluation of Fibrogenic Cytokines in Lung Fibrosis Academic Article
Reactivity and radiochemical yield of [¹⁸F]F2 from ¹⁸O(p,n)¹⁸F target: 'SINGLE-SHOOT' vs 'DOUBLE-SHOOT' method for the production of [¹⁸F]F2 Conference Paper
Repeated recovery, distillation and reuse of oxygen-18 water in ¹⁸O(p,n)¹⁸F high pressure target Conference Paper
Reproductive Toxicology of Environmental Toxicants: Emerging Issues and Concerns Academic Article
Residual Vein Thrombosis and D-Dimer for Optimizing Duration of Anticoagulation in Idiopathic Deep Vein Thrombosis Academic Article
Reversal of target-specific oral anticoagulants Academic Article
Reversing Anticoagulant Therapy Academic Article
Role of DAP12 in Innate and Adaptive Immune Responses Academic Article
Role of Dendritic Cell-Derived Cytokines in Immune Regulation Academic Article
SYNTHESIS OF 18F-RADIOTRACERS IN HIGH SPECIFIC ACTIVITY USING THE FLUOROUS APPROACH Conference Paper
SYNTHESIS, ANTIFUNGAL AND ANTI-BACTERIAL ACTIVITY OF AMINOALKYL KETONES IN SULFUR HETEROCYCLIC SERIES Academic Article
SYNTHESIS, RADIOLABELLING AND BIOLOGICAL EVALUATION OF TARGETED METALLACARBORANE (M=99MTc) DERIVATIVES FOR IMAGING NEURORECEPTORS Conference Paper
Safety and Efficacy of Ximelagatran: Meta-Analysis of the Controlled Randomized Trials for the Prophylaxis or Treatment of Venous Thromboembolism Academic Article
Screening in Academe: A Perspective on Implementation of University-Based Small Molecule Screening Academic Article
Screening of ligands for redox-active europium using magnetic resonance imaging Academic Article
Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids Academic Article
Side chain flexibility and the pore dimensions in the GABAA receptor Academic Article
Simultaneous synthesis of ¹⁸F-labelled 6-fluoro-m-tyramine and 6-fluoro-3-hydroxy phenylacetic acid: ¹⁸F-containing metabolites of [¹⁸F]6-fluoro-m-tyrosine Conference Paper
Single amino acid chelate complexes of the M(CO)3+core for correlating fluorescence and radioimaging studies (M = 99mTc or Re) Academic Article
Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects Academic Article
Small molecule functional discrimination of the kinases required for the microbial synthesis of threonine and isoleucine Academic Article
Small molecule immunomodulins from cultures of the human microbiome member Lactobacillus plantarum Academic Article
Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria Academic Article
Structural–Functional Studies of Burkholderia cenocepacia d-Glycero-β-d-manno-heptose 7-Phosphate Kinase (HldA) and Characterization of Inhibitors with Antibiotic Adjuvant and Antivirulence Properties Academic Article
Structure-activity studies on N -Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation Academic Article
Structures and biosynthesis of 12-membered macrocyclic depsipeptides from Streptomyces sp. ML55 Academic Article
Structure–activity studies of echinomycin antibiotics against drug-resistant and biofilm-forming Staphylococcus aureus and Enterococcus faecalis Academic Article
Structure–activity studies on acetylcholinesterase inhibition in the lycorine series of Amaryllidaceae alkaloids Academic Article
Structure–activity studies on seco-pancratistatin analogs: Potent inhibitors of human cytochrome P450 3A4 Academic Article
Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore Academic Article
Synthesis and Biological Activity of a Focused Library of Mitogen-activated Protein Kinase Phosphatase Inhibitors Academic Article
Synthesis and Biological Evaluation of Fully Functionalized seco-Pancratistatin Analogues Academic Article
Synthesis and Characterization of Rhenium and Technetium-99m Labeled Insulin Academic Article
Synthesis and Dopamine Receptor Modulating Activity of 3-Substituted γ-Lactam Peptidomimetics of l-Prolyl-l-leucyl-glycinamide Academic Article
Synthesis and Dopamine Receptor Modulating Activity of Novel Peptidomimetics ofl-Prolyl-l-leucyl-glycinamide Featuring α,α-Disubstituted Amino Acids Academic Article
Synthesis and Dopamine Receptor Modulating Activity of Substituted Bicyclic Thiazolidine Lactam Peptidomimetics of l-Prolyl-l-leucyl-glycinamide Academic Article
Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation Academic Article
Synthesis and Evaluation of Radioiodinated Acyloxymethyl Ketones as Activity-Based Probes for Cathepsin B Academic Article
Synthesis and Screening of Mono- and Di-Aryl Technetium and Rhenium Metallocarboranes. A New Class of Probes for the Estrogen Receptor Academic Article
Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide Academic Article
Synthesis and Structure−Activity Relationships of Truncated Bisubstrate Inhibitors of Aminoglycoside 6‘-N-Acetyltransferases Academic Article
Synthesis and antifilarial evaluation of N1,N n- xylofuranosylated diaminoalkanes Academic Article
Synthesis and biological evaluation of analogs of Pro-Leu-Gly-NH2 modified at the leucyl residue Academic Article
Synthesis and characterisation of13C and15N isotopomers of a 1-acyl-7-nitroindoline Academic Article
Synthesis and dopamine receptor modulating activity of lactam conformationally constrained analogs of Pro-Leu-Gly-NH2 Academic Article
Synthesis and dopamine receptor modulating activity of unsubstituted and substituted triproline analogues of l-prolyl-l-leucyl-glycinamide (PLG) Academic Article
Synthesis and evaluation of photoaffinity probes directed at lanosterol 14α-demethylase (P-45014DM) Academic Article
Synthesis and in Vitro Evaluation of 18F- and 19F-Labeled Insulin: A New Radiotracer for PET-based Molecular Imaging Studies Academic Article
Synthesis and inhibitory action on HMG-CoA synthase of racemic and optically active oxetan-2-ones (β-Lactones) Academic Article
Synthesis and structure-activity relationships among glycosidic derivatives of 4'-demethylepipodophyllotoxin and epipodophyllotoxin, showing VM26- and VP16-213-like activities. Academic Article
Synthesis of Pro-Leu-Gly-NH2 analogs modified at the prolyl residue and evaluation of their effects on the receptor binding activity of the central dopamine receptor agonist, ADTN Academic Article
Synthesis of cholesteryl esters of labelled fatty acids Academic Article
Synthesis of f-18 labelled fluoro-melatonins and 5-hydroxy-fluoro-tryptophans Academic Article
Synthesis of fluorine-18 labelled 5-fluoro-L-DOPA by direct fluorination of L-DOPA Conference Paper
Synthesis of non-nucleoside anti-viral cyclopropylcarboxacyl hydrazones and initial anti-HSV-1 structure-activity relationship studies Academic Article
Synthesis of α-methylstilbenes using an aqueous Wittig methodology and application toward the development of potent human aromatase inhibitors Academic Article
Synthetic Glucocorticoids: Antenatal Administration and Long-term Implications Academic Article
Systems Medicine Approaches for the Definition of Complex Phenotypes in Chronic Diseases and Ageing. From Concept to Implementation and Policies Academic Article
TEMPERATURE EFFECT ON THE STEREOSPECIFICITY OF NUCLEOPHILIC FLUORINATION: FORMATION OF [18F]TRANS-4-FLUORO-L-PROLINE DURING THE SYNTHESIS OF [18F]CIS-4-FLUORO-L-PROLINE Conference Paper
THE PREPARATION AND IN VITRO EVALUATION OF CARBORANE SELECTIVE ESTROGEN RECEPTOR MODULATORS Conference Paper
Taking aim at wall teichoic acid synthesis: new biology and new leads for antibiotics Academic Article
Temperature effects on the stereospecificity of nucleophilic fluorination: formation of trans-[18F]4-fluoro-l-proline during the synthesis of cis-[18F]4-fluoro-l-proline Academic Article
The AMP-Activated Protein Kinase: Role in Regulation of Skeletal Muscle Metabolism and Insulin Sensitivity Academic Article
The Development of New Factor Xa Inhibitors Based on Amide Synthesis Academic Article
The Effects of Commercial Preparations of Herbal Supplements Commonly Used by Women on the Biotransformation of Fluorogenic Substrates by Human Cytochromes P450 Academic Article
The First Organometallic Selective Estrogen Receptor Modulators (SERMs) and Their Relevance to Breast Cancer Academic Article
The Hunt for New Tuberculosis Vaccines: Anti-TB Immunity and Rational Design of Vaccines Academic Article
The Identification of 5-Hydroxyl-L-norvaline in Cultures of Pyridoxine Auxotrophs of Escherichia coli B Academic Article
The Role of IL-15 Signaling in the Induction of Innate Antiviral Responses Academic Article
The discovery of rofecoxib, [MK 966, VIOXX®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor Academic Article
The effects of different concentrations of saffron (Crocus sativus) decoction on preterm delivery in mice Conference Paper
The new potent immunosuppressant FK-506 reverses multidrug resistance in Chinese hamster ovary cells. Academic Article
The sequential production of [¹⁸F]-6-FDOPA and [¹⁸F]-F-m-tyrosine (or [¹⁸F]-2-FDG) from the same dilute [¹⁸F]F2 target gas Conference Paper
Therapeutic Peptides: New Arsenal Against Drug Resistant Pathogens Academic Article
Therapeutic advances in the treatment of osteoporosis Academic Article
Therapeutic approaches for haemophilia Academic Article
Therapeutic patents for the treatment of premenstrual syndrome and premenstrual dysphoric disorder: historical perspectives and future directions Academic Article
Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase Academic Article
Thiopeptides: antibiotics with unique chemical structures and diverse biological activities Academic Article
Three new polyketides from fruiting bodies of the endophytic ascomycete Xylaria polymorpha Academic Article
Tifacogin (Chiron Corp/Pharmacia Corp). Academic Article
Triazole Appending Agent (TAAG): A new hydrophilic iodine-containing prosthetic group for the preparation of targeted radiopharmaceuticals Conference Paper
Trifluoromethanesulfonic acid, an alternative solvent medium for the direct electrophilic fluorination of DOPA: new syntheses of 6-[18F]fluoro-L-DOPA and 6-[18F]fluoro-D-DOPA Academic Article
Tris(3-hydroxypropyl)phosphine (THPP): A mild, air-stable reagent for the rapid, reductive cleavage of small-molecule disulfides Academic Article
Using chemical bonds to analyze data retrieved from the inorganic crystal structure database Academic Article
Winners of the 2013 JA Medals for excellence Academic Article
Winners of the 2014 JA Medals for excellence Academic Article
[F-18]Fluoro-meta-L-tyrosine is a better PET tracer than [F-18]fluoro-L-dopa for the deliniation of dopaminergic structures in the human brain Conference Paper
eta(5)-TYPE ORGANOMETALLIC COMPOUNDS AND THE PREPARATION OF Tc RADIOTRACERS Conference Paper
iso-Lactam and reduced amide analogues of the peptidomimetic dopamine receptor modulator 3(R)-[(2(S)-Pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide Academic Article
β-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents Academic Article
“I am a healthcare practitioner”: A qualitative exploration of massage therapists’ professional identity Academic Article
“Just don’t be creepy”: A phenomenological study of the experiences of men in massage therapy Academic Article

Medicinal & Biomolecular Chemistry Concept

Vocabulary Service

Overview

subject area of