Journal article
Screening of ligands for redox-active europium using magnetic resonance imaging
Abstract
We report a screening procedure to predict ligand coordination to EuII and EuIII using magnetic resonance imaging in which bright images indicate complexation and dark images indicate no complexation. Here, paramagnetic GdIII is used as a surrogate for EuIII in the screening procedure to enable detection with magnetic resonance imaging. The screening procedure was tested using a set of eight ligands with known coordination to EuII and EuIII, …
Authors
Corbin BA; Basal LA; White SA; Shen Y; Haacke EM; Fishbein KW; Allen MJ
Journal
Bioorganic & Medicinal Chemistry, Vol. 26, No. 19, pp. 5274–5279
Publisher
Elsevier
Publication Date
10 2018
DOI
10.1016/j.bmc.2018.04.001
ISSN
0968-0896