Synthesis of f‐18 labelled fluoro‐melatonins and 5‐hydroxy‐fluoro‐tryptophans Journal Articles uri icon

  •  
  • Overview
  •  
  • Research
  •  
  • Identity
  •  
  • Additional Document Info
  •  
  • View All
  •  

abstract

  • AbstractReaction of dilute [F‐18]fluorine gas with either melatonin or 5‐hydroxy‐tryptophan in hydrogen fluoride at −70°C gives 6‐fluoro‐melatonin or 4‐ and 6‐fluoro‐5‐hydroxytryptophan. They are of potential use in Positron Emission Tomography to image the binding sites for melatonin and to study the metabolism of serotonin.

publication date

  • January 1988