Journal article
Safety and efficacy of ximelagatran: meta-analysis of the controlled randomized trials for the prophylaxis or treatment of venous thromboembolism.
Abstract
BACKGROUND: Ximelagatran has been approved in Europe for VTE prophylaxis in orthopedic surgery at fixed doses and without laboratory monitoring. Aim of the study was to evaluate safety and efficacy of ximelagatran in a meta-analysis of prophylaxis and/or treatment randomized controlled trials.
METHODS: Absolute risk of events for ximelagatran and OR for its comparison with LMWH and coumarins were calculated. Subgroup analysis was performed for …
Authors
Iorio A; Guercini F; Ferrante F; Nenci GG
Journal
Current Pharmaceutical Design, Vol. 11, No. 30, pp. 3893–3918
Publisher
Bentham Science Publishers
Publication Date
2005
DOI
10.2174/138161205774580534
ISSN
1381-6128