Macplocimine A, a new 18-membered macrolide isolated from the filamentous sulfur bacteria Thioploca sp. Journal Articles uri icon

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  • Macplocimine A (1), a rare naturally occurring 18-membered macrolide, was isolated from the marine-derived filamentous sulfur bacteria Thioploca sp. The structure was determined by a combination of spectroscopic techniques, including HRESIMS, 1D and 2D NMR analyses. 1 features a thymine group, which is attached to an aromatic fused 18-membered macrolide ring structure derived from a polyketide synthase biosynthetic pathway.


  • Li, Xiang
  • Vanner, Stephanie
  • Wang, Wenliang
  • Li, Yongchang
  • Gallardo, Victor Ariel
  • Magarvey, Nathan

publication date

  • July 2013