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Journal article

Crystal structure of tert.‐butyloxycarbonyl‐L‐prolyl‐D‐alanyl‐D‐alanyl‐N‐methylamide Dimeric β‐sheet formation

Abstract

The crystal structure of the tripeptide t-Boc-L-Pro-D-Ala-D-Ala-NHCH3, monohydrate, (C17H30N4O5.H2O, molecular weight = 404.44) has been determined by single crystal X-ray diffraction. The crystals are monoclinic, space group P2(1), a = 9.2585(4), b = 9.3541(5), c = 12.4529(4)A, beta = 96.449(3) degrees, Z = 2. The peptide units are in the trans and the tBoc-Pro bond in the cis orientation. The first and third peptide units show significant …

Authors

ANANTHANARAYANAN VS; BOULAY G; MARY JS; SUBRAMANIAN E; MICHEL AG

Journal

Chemical Biology & Drug Design, Vol. 39, No. 5, pp. 458–463

Publisher

Wiley

Publication Date

5 1992

DOI

10.1111/j.1399-3011.1992.tb01450.x

ISSN

1747-0277