Journal article
Antileishmanial macrolides from ant-associated Streptomyces sp. ISID311
Abstract
Three antifungal macrolides cyphomycin (1), caniferolide C (2) and GT-35 (3) were isolated from Streptomyces sp. ISID311, a bacterial symbiont associated with Cyphomyrmex fungus-growing ants. The planar structures of these compounds were established by 1 and 2D NMR data and MS analysis. The relative configurations of 1-3 were established using Kishi's universal NMR database method, NOE/ROE analysis and coupling constants analysis assisted by …
Authors
Ortega HE; Lourenzon VB; Chevrette MG; Ferreira LLG; Alvarenga RFR; Melo WGP; Venâncio T; Currie CR; Andricopulo AD; Bugni TS
Journal
Bioorganic & Medicinal Chemistry, Vol. 32, ,
Publisher
Elsevier
Publication Date
2 2021
DOI
10.1016/j.bmc.2021.116016
ISSN
0968-0896