Journal article
Therapeutic approaches for haemophilia
Abstract
The life-long episodic bleeding associated with inherited deficiencies of blood coagulation Factor VIII (FVIII) or Factor IX (FIX) can be well controlled with periodic iv. injections of FVIII or FIX concentrates. Either concentrate can be isolated from large human pools (i.e., plasma-derived FVIII or FIX concentrate) or from culture supernatants of recombinant cells engineered to secrete FVIII or FIX. The validated viral inactivation strategies …
Authors
Hortelano G; Ofosu FA
Journal
Expert Opinion on Therapeutic Patents, Vol. 10, No. 6, pp. 929–938
Publisher
Taylor & Francis
Publication Date
June 2000
DOI
10.1517/13543776.10.6.929
ISSN
1354-3776