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Modulation of Salmonella gene expression by...
Journal article

Modulation of Salmonella gene expression by subinhibitory concentrations of quinolones

Abstract

Approximately 2.7% of a collection of Salmonella enterica var. Typhimurium promoter-lux reporter strains showed altered transcriptional patterns when exposed to low concentrations of nine different fluoroquinolones (FQs). Even at the subinhibitory concentrations employed, all nine FQs upregulated genes involved in the SOS response, umuD, lexA, sbmC and dinP. In addition, transcriptional regulators, genes putatively associated with membrane …

Authors

Yim G; McClure J; Surette MG; Davies JE

Journal

The Journal of Antibiotics, Vol. 64, No. 1, pp. 73–78

Publisher

Springer Nature

Publication Date

1 2011

DOI

10.1038/ja.2010.137

ISSN

0021-8820