Insulin - McMaster Experts

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A 24-Week, Randomized, Treat-to-Target Trial Comparing Initiation of Insulin Glargine Once-Daily With Insulin Detemir Twice-Daily in Patients With Type 2 Diabetes Inadequately Controlled on Oral Glucose-Lowering Drugs Academic Article
A Comparison of the Metabolic Response to Abdominal Obesity in Two Canadian Inuit and First Nations Population Academic Article
A Genome-Wide Association Study Identifies a Novel Major Locus for Glycemic Control in Type 1 Diabetes, as Measured by Both A1C and Glucose Academic Article
A Mechanism of Extreme Growth and Reliable Signaling in Sexually Selected Ornaments and Weapons Academic Article
A Polymorphism Within the G6PC2 Gene Is Associated with Fasting Plasma Glucose Levels Academic Article
A Systematic Review and Meta-Analysis of Hypoglycemia and Cardiovascular Events: A comparison of glyburide with other secretagogues and with insulin Academic Article
A Transgenic Mouse Model to Study Glucose Transporter 4myc Regulation in Skeletal Muscle Academic Article
A comprehensive metabolic evaluation reveals impaired glucose metabolism and dyslipidemia in breast cancer patients early in the disease trajectory Academic Article
A general mechanism for conditional expression of exaggerated sexually-selected traits Academic Article
A randomized trial of adding insulin glargine vs. avoidance of insulin in people with Type 2 diabetes on either no oral glucose-lowering agents or submaximal doses of metformin and/or sulphonylureas. The Canadian INSIGHT (Implementing New Strategies with Insulin Glargine for Hyperglycaemia Treatment) Study Academic Article
A single dose of sodium nitrate does not improve oral glucose tolerance in patients with type 2 diabetes mellitus Academic Article
A stepped wedge design for testing an effect of intranasal insulin on cognitive development of children with Phelan-McDermid syndrome: A comparison of different designs Academic Article
AMP-activated protein kinase (AMPK) 1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise Academic Article
AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice Academic Article
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity Academic Article
AMPK β1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance Academic Article
Ablating the protein TBC1D1 impairs contraction-induced sarcolemmal glucose transporter 4 redistribution but not insulin-mediated responses in rats Academic Article
Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression Academic Article
Action of insulin in rat adipocytes and membrane properties Academic Article
Actions of growth factors in the follicle Academic Article
Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro Academic Article
Addition of glutamine to essential amino acids and carbohydrate does not enhance anabolism in young human males following exercise Academic Article
Adipocyte Hypertrophy, Fatty Liver and Metabolic Risk Factors in South Asians: The Molecular Study of Health and Risk in Ethnic Groups (mol-SHARE) Academic Article
Adiponectin is associated with cardio-metabolic traits in Mexican children Academic Article
Adiponectin, leptin and insulin in breast milk: associations with maternal characteristics and infant body composition in the first year of life Academic Article
Adjusting insulin doses in patients with type 1 diabetes who use insulin pump and continuous glucose monitoring: Variations among countries and physicians Academic Article
Adverse metabolic effects of a hypercaloric, high-fat diet in rodents precede observable changes in body weight Academic Article
Alterations in cardiac flow parameters in patients with polycystic ovarian syndrome Academic Article
Alterations in human muscle protein metabolism with aging: Protein and exercise as countermeasures to offset sarcopenia Academic Article
Altered Calcium Homeostasis Is Correlated With Abnormalities of Fasting Serum Glucose, Insulin Resistance, and -Cell Function in the Newfoundland Population Academic Article
Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes Academic Article
Aminoacidemia following ingestion of native whey protein, micellar casein, and a whey-casein blend in young men Academic Article
Analysis of Health Utility Data When Some Subjects Attain the Upper Bound of 1: Are Tobit and CLAD Models Appropriate? Academic Article
Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study Academic Article
Aromatase activity in granulosa cells: Regulation by growth factors Academic Article
Association Analysis Indicates That a Variant GATA-Binding Site in the PIK3CB Promoter Is a Cis-Acting Expression Quantitative Trait Locus for This Gene and Attenuates Insulin Resistance in Obese Children Academic Article
Association Studies on Ghrelin and Ghrelin Receptor Gene Polymorphisms With Obesity Academic Article
Association of Hematological Parameters with Insulin Resistance and β-Cell Dysfunction in Nondiabetic Subjects Academic Article
Availability and affordability of essential medicines for diabetes across high-income, middle-income, and low-income countries: a prospective epidemiological study Academic Article
Beta-blockade, but not normoglycemia or hyperinsulinemia, markedly diminishes stress-induced hyperglycemia in diabetic dogs Academic Article
Body-weight-support treadmill training improves blood glucose regulation in persons with incomplete spinal cord injury Academic Article
Bone marrow–derived stem cells initiate pancreatic regeneration Academic Article
CONCEPTT: Continuous Glucose Monitoring in Women with Type 1 Diabetes in Pregnancy Trial: A multi-center, multi-national, randomized controlled trial - Study protocol Academic Article
Caloric Restriction Induces Changes in Insulin and Body Weight Measurements That Are Inversely Associated with Subsequent Weight Regain Academic Article
Can community retail pharmacist and diabetes expert support facilitate insulin initiation by family physicians? Results of the AIM@GP randomized controlled trial Academic Article
Can family physicians help patients initiate basal insulin therapy successfully?: randomized trial of patient-titrated insulin glargine compared with standard oral therapy: lessons for family practice from the Canadian INSIGHT trial. Academic Article
Carbohydrate Does Not Augment Exercise-Induced Protein Accretion versus Protein Alone Academic Article
Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans Academic Article
Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man Academic Article
Carbohydrate metabolism during prolonged exercise and recovery: interactions between pyruvate dehydrogenase, fatty acids, and amino acids Academic Article
Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity Academic Article
Cardiovascular Outcomes Trials in Type 2 Diabetes: Where Do We Go From Here? Reflections From aDiabetes CareEditors’ Expert Forum Academic Article
Cardiovascular events and all-cause mortality associated with sulphonylureas compared with other antihyperglycaemic drugs: A Bayesian meta-analysis of survival data Academic Article
Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis Academic Article
Challenges in Pharmacotherapeutics Education for Diabetes in Real-World Clinical Settings: Views From Family Medicine and Internal Medicine Residents Academic Article
Challenges in the conduct of large simple trials of important generic questions in resource-poor settings: The CREATE and ECLA trial program evaluating GIK (glucose, insulin and potassium) and low-molecular-weight heparin in acute myocardial infarction Academic Article
Changes in traditional chronic disease risk factors over time and their relationship with leisure-time physical activity in people living with spinal cord injury Academic Article
Characterization of the pancreatic hormones from the Brockmann body of the tilapia: implications for islet xenograft studies Academic Article
Charge-Switching, Amphoteric Glucose-Responsive Microgels with Physiological Swelling Activity Academic Article
Chronic Leptin Administration Decreases Fatty Acid Uptake and Fatty Acid Transporters in Rat Skeletal Muscle Academic Article
Clinical correlates of hypoglycaemia over 4 years in people with type 2 diabetes starting insulin: An analysis from the CREDIT study Academic Article
Clinical inertia in patients with T2DM requiring insulin in family practice. Academic Article
Clinical outcomes associated with the use of subcutaneous insulin-by-glucose sliding scales to manage hyperglycemia in hospitalized patients with pneumonia Academic Article
Cloning, sequencing and characterization of the tilapia insulin gene Academic Article
Cognitive Function and Anticoagulation Control in Patients With Atrial Fibrillation Academic Article
Coingestion of protein with carbohydrate during recovery from endurance exercise stimulates skeletal muscle protein synthesis in humans Academic Article
Computerized clinical decision support systems for therapeutic drug monitoring and dosing: A decision-maker-researcher partnership systematic review Academic Article
Condition-related predictors of successful transition from paediatric to adult care among adolescents with Type 1 diabetes Academic Article
Conditioning insulin effects. Academic Article
Conditioning of insulin-induced glycemia. Academic Article
Conditioning of insulin-induced hyperphagia. Academic Article
Conjugated linoleic acid increases skeletal muscle ceramide content and decreases insulin sensitivity in overweight, non-diabetic humans Academic Article
Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial Academic Article
Contractile and Nutritional Regulation of Human Muscle Growth Academic Article
Cortisol Responses to the Insulin Hypoglycaemia Test in Children Academic Article
Creatine supplementation affects sprint endurance in juvenile rainbow trout Academic Article
Defining Obesity Cut Points in a Multiethnic Population Academic Article
Design of FLAT-SUGAR: Randomized Trial of Prandial Insulin Versus Prandial GLP-1 Receptor Agonist Together With Basal Insulin and Metformin for High-Risk Type 2 Diabetes Academic Article
Development of leptin resistance in rat soleus muscle in response to high-fat diets Academic Article
Diabetes and cardiovascular disease: explaining the relationship. Academic Article
Diabetic ketoacidosis as first presentation of type 1 diabetes mellitus in a young child: Important differential diagnosis for respiratory distress. Academic Article
Diabetic myopathy differs betweenIns2Akita+/−and streptozotocin-induced Type 1 diabetic models Academic Article
Diagnostic yield of fibre-optic endoscopy in the operated stomach Academic Article
Diet-Induced Developmental Acceleration Independent of TOR and Insulin in C. elegans Academic Article
Dietary glycemic index, glycemic load, and the risk of breast cancer in an Italian prospective cohort study Academic Article
Dietary patterns in men and women are simultaneously determinants of altered glucose metabolism and bone metabolism Academic Article
Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters to the plasma membrane. Academic Article
Does Insulin Therapy Promote, Reduce, or Have a Neutral Effect on Cancers? Academic Article
Does a Patient-Managed Insulin Intensification Strategy With Insulin Glargine and Insulin Glulisine Provide Similar Glycemic Control as a Physician-Managed Strategy? Results of the START (Self-Titration With Apidra to Reach Target) Study Academic Article
Dose threshold for radiation induced fetal programming in a mouse model at 4 months of age: Hepatic expression of genes and proteins involved in glucose metabolism and glucose uptake in brown adipose tissue Academic Article
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human Academic Article
Dysglycaemia and risk of cardiovascular disease Academic Article
Ectopic fat in youth: The contribution of hepatic and pancreatic fat to metabolic disturbances Academic Article
Effect of 7 days of exercise on exogenous carbohydrate oxidation and insulin resistance in children with obesity Academic Article
Effect of Environmental Contaminants on Beta Cell Function Academic Article
Effect of Fructose on Glycemic Control in Diabetes: A systematic review and meta-analysis of controlled feeding trials Academic Article
Effect of Glucose-Insulin-Potassium Infusion on Mortality in Patients With Acute ST-Segment Elevation Myocardial Infarction Academic Article
Effect of JTT-501 on net hepatic glucose balance and peripheral glucose uptake in alloxan-induced diabetic dogs Academic Article
Effect of Metformin vs Placebo on and Metabolic Factors in NCIC CTG MA.32 Academic Article
Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes Academic Article
Effect of Perioperative Insulin Infusion on Surgical Morbidity and Mortality: Systematic Review and Meta-analysis of Randomized Trials Conference Paper
Effect of Tree Nuts on Glycemic Control in Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Dietary Trials Academic Article
Effect of combining rosiglitazone with either metformin or insulin on β-cell mass and function in an animal model of Type 2 diabetes characterized by reduced β-cell mass at birth Academic Article
Effect of fenugreek (Trigonella foenum-graecumL.) intake on glycemia: a meta-analysis of clinical trials Academic Article
Effect of glycogen availability on human skeletal muscle protein turnover during exercise and recovery Academic Article
Effect of intensive therapy on early macrovascular disease in young individuals with type 1 diabetes. A systematic review and meta-analysis. Academic Article
Effect of targeting normal fasting glucose levels with basal insulin glargine on glycaemic variability and risk of hypoglycaemia: a randomized, controlled study in patients with early Type 2 diabetes Academic Article
Effect of thiazolidinediones and insulin on cognitive outcomes in ACCORD-MIND Academic Article
Effects of Aerobic Training, Resistance Training, or Both on Percentage Body Fat and Cardiometabolic Risk Markers in Obese Adolescents Academic Article
Effects of Hypotensive Doses of Prostaglandin A₁ on Plasma Glucose, Free Fatty Acids and Insulin in Reserpinized Dogs Academic Article
Effects of Low-Carbohydrate vs Low-Fat Diets on Weight Loss and Cardiovascular Risk Factors Academic Article
Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue Academic Article
Effects of Short-Term Exercise Training With and Without Milk Intake on Cardiometabolic and Inflammatory Adaptations in Obese Adolescents Academic Article
Effects of Theophylline on Glucose Kinetics in Normal and Sympathectomized Rats Academic Article
Effects of antecedent hypoglycemia, hyperinsulinemia, and excess corticosterone on hypoglycemic counterregulation Academic Article
Effects of diabetes and insulin on betaine-homocysteineS-methyltransferase expression in rat liver Academic Article
Effects of dynamic exercise intensity on the activation of hormone-sensitive lipase in human skeletal muscle Academic Article
Effects of higher-versus lower-protein diets on health outcomes: a systematic review and meta-analysis Academic Article
Effects of improvement in aerobic power on resting insulin and glucose concentrations in children Academic Article
Effects of lithium administration on plasma catecholamines Academic Article
Effects of lithium, nortriptyline and dexamethasone on insulin sensitivity Academic Article
Effects of long-term lithium treatment on prolactin regulation. Academic Article
Effects of potassium citrate or potassium chloride in patients with combined glucose intolerance: A placebo-controlled pilot study Academic Article
Effects of recurrent hyperinsulinemia with and without hypoglycemia on counterregulation in diabetic rats Academic Article
Emergency interventions for hyperkalaemia Academic Article
Emulsion Reactors: A New Technique for the Preparation of Molecular Imaging Probes Academic Article
Endurance exercise training increases adipose tissue glucocorticoid exposure: adaptations that facilitate lipolysis Academic Article
Endurance training in obese humans improves glucose tolerance and mitochondrial fatty acid oxidation and alters muscle lipid content Academic Article
Endurance training without weight loss lowers systemic, but not muscle, oxidative stress with no effect on inflammation in lean and obese women Academic Article
Enhanced Amino Acid Sensitivity of Myofibrillar Protein Synthesis Persists for up to 24 h after Resistance Exercise in Young Men Academic Article
Enhanced Expression and Secretion of an Epithelial Membrane Antigen (MA5) in a Human Mucinous Breast Tumor Line (BT549) Academic Article
Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors Academic Article
Evaluating the evidence for macrophage presence in skeletal muscle and its relation to insulin resistance in obese mice and humans: a systematic review protocol Academic Article
Evaluation of the Role of the Sympathetic Nervous System in the Glucoregulatory Response to Insulin-Induced Hypoglycemia in the Rat Academic Article
Evidence of extensive atherosclerosis, coronary artery disease and myocardial infarction in the ApoE−/−:Ins2 mouse fed a western diet Academic Article
Exercise intensity and insulin sensitivity: how low can you go? Academic Article
Failure of Protein to Improve Time Trial Performance when Added to a Sports Drink Academic Article
Fasting Insulin and Outcome in Early-Stage Breast Cancer: Results of a Prospective Cohort Study Academic Article
Fasting glucose is a risk factor for breast cancer: a prospective study. Academic Article
Feasibility of a Lifestyle Intervention on Body Weight and Serum Biomarkers in Breast Cancer Survivors with Overweight and Obesity Academic Article
Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 diabetes Academic Article
Flux Through the Hexosamine Pathway Is a Determinant of Nuclear Factor B- Dependent Promoter Activation Academic Article
Food sources of fructose-containing sugars and glycaemic control: systematic review and meta-analysis of controlled intervention studies Academic Article
GPs' approach to insulin prescribing in older patients: a qualitative study Academic Article
Gender differences in substrate for endurance exercise Academic Article
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge Academic Article
Glucocorticoid-Induced Preterm Birth and Neonatal Hyperglycemia Alter Ovine β-Cell Development Academic Article
Glucoregulatory Mechanisms Following Hypophysectomy in Diabetic Dogs with Residual Insulin Secretion Academic Article
Glucoregulatory Response to Insulin-Induced Hypoglycemia in Laennec’s Cirrhosis Academic Article
Glucose Ingestion Matched with Total Carbohydrate Utilization Attenuates Hypoglycemia during Exercise in Adolescents with IDDM Academic Article
Glucose and insulin abnormalities relate to functional capacity in patients with congestive heart failure Academic Article
Glucose ingestion and substrate utilization during exercise in boys with IDDM Academic Article
Glucose-Insulin-Potassium Therapy in Patients With ST-Segment Elevation Myocardial Infarction Academic Article
Glucose-insulin-potassium infusion and mortality in the CREATE-ECLA trial. Academic Article
Glucose-insulin-potassium infusion in acute myocardial infarction Academic Article
Glucose: a Continuous Risk Factor for Cardiovascular Disease Academic Article
Glutamate availability is important in intramuscular amino acid metabolism and TCA cycle intermediates but does not affect peak oxidative metabolism Academic Article
Glutamate ingestion and its effects at rest and during exercise in humans Academic Article
Glutamate ingestion: the plasma and muscle free amino acid pools of resting humans Academic Article
Glutamate supplementation is associated with improved glucose metabolism following carbohydrate ingestion in healthy males Academic Article
Glycemic control in the ICU: a multicenter survey Academic Article
Glycogen Synthase Kinase 3α-Specific Regulation of Murine Hepatic Glycogen Metabolism Academic Article
Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword? Academic Article
Glycogenin protein and mRNA expression in response to changing glycogen concentration in exercise and recovery Academic Article
Green tea extract does not affect exogenous glucose appearance but reduces insulinemia with glucose ingestion in exercise recovery Academic Article
Growth factors and the regulation of fetal growth. Academic Article
Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients Academic Article
Gut microbiota impairs insulin clearance in obese mice Academic Article
Hepatic Glucose Intolerance Precedes Hepatic Steatosis in the Male Aromatase Knockout (ArKO) Mouse Academic Article
Hepatic extraction of insulin after stimulation of secretion with oral glucose or parenteral nutrients Academic Article
Hepatic glucose regulation and metabolism in adult sheep: effects of prenatal betamethasone Academic Article
Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction Academic Article
High insulin levels in newly diagnosed breast cancer patients reflect underlying insulin resistance and are associated with components of the insulin resistance syndrome Academic Article
High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus Academic Article
Hormonal Regulation of Cystathionine β-Synthase Expression in Liver Academic Article
Human skeletal muscle PDH kinase activity and isoform expression during a 3-day high-fat/low-carbohydrate diet Academic Article
Hyperglycemia promotes insulin-independent ovarian tumor growth Academic Article
Hypoglycemia: The Dangerous Side of Great Control Academic Article
INS VNTR Is Not Associated With Childhood Obesity in 1,023 Families: A Family-based Study Academic Article
Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion Academic Article
Immunohistochemical staining for tilapia and human insulin demonstrates that a tilapia transgenic for humanized insulin is a mosaic Academic Article
Immunometabolism of obesity and diabetes: microbiota link compartmentalized immunity in the gut to metabolic tissue inflammation Academic Article
Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity Academic Article
Impaired endothelial antithrombotic activity following short-term interruption of continuous subcutaneous insulin infusion in type1 diabetic patients Academic Article
Impaired renal function modifies the risk of severe hypoglycaemia among users of insulin but not glyburide: a population-based nested case–control study Academic Article
Implication of the Pro12Ala polymorphism of the PPAR-gamma 2gene in type 2 diabetes and obesity in the French population Academic Article
Importance of glucagon in mediating epinephrine-induced hyperglycemia in alloxan-diabetic dogs Academic Article
Improved glycemic control by acarbose therapy in hypertensive diabetic patients: effects on blood pressure and hormonal parameters Academic Article
In high-risk T1DM, real-time continuous glucose monitoring vs self-monitoring reduced hypoglycemic events Academic Article
In vitro and in vivo antidiabetic activity of isolated fraction of Prosopis cineraria against streptozotocin-induced experimental diabetes: A mechanistic study Academic Article
Increased skeletal muscle glucose uptake by rosemary extract through AMPK activation Academic Article
Increases in glycogenin and glycogenin mRNA accompany glycogen resynthesis in human skeletal muscle Academic Article
Induction of Ca2+ transport in liposomes by insulin Academic Article
Inflammation promotes adipocyte lipolysis via IRE1 kinase Academic Article
Influence of Aerobic Power and Percent Body Fat on Cardiovascular Disease Risk in Youth Academic Article
Influence of differing macronutrient intakes on muscle glycogen resynthesis after resistance exercise Academic Article
Influence of nephrectomy on the glucoregulatory response to insulin administration in the rat Academic Article
Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men Academic Article
Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Academic Article
Insulin Activates a p21-activated Kinase in Muscle Cells via Phosphatidylinositol 3-Kinase Academic Article
Insulin Receptor Autophosphorylation and Signaling is Altered by Modulation of Membrane Physical Properties Academic Article
Insulin Therapy in People Who Have Dysglycemia and Type 2 Diabetes Mellitus: Can It Offer Both Cardiovascular Protection and Beta-Cell Preservation? Academic Article
Insulin acutely decreases hepatic fatty acid synthase activity Academic Article
Insulin and muscle protein turnover in humans: stimulatory, permissive, inhibitory, or all of the above? Academic Article
Insulin as an Amplifier of Gonadotropin Action on Steroid Production: Mechanisms and Sites of Action in Goldfish Prematurational Full-Grown Ovarian Follicles Academic Article
Insulin dysfunction and allostatic load in bipolar disorder Academic Article
Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle Academic Article
Insulin signaling and limb-patterning: candidate pathways for the origin and evolutionary diversification of beetle ‘horns’ Academic Article
Insulin signalling in mushroom body neurons regulates feeding behaviour in Drosophila larvae Academic Article
Insulin therapy in acute coronary syndromes: an appraisal of completed and ongoing randomised trials with important clinical end points Academic Article
Insulin treatment and clinical outcomes in patients with diabetes and heart failure with preserved ejection fraction Academic Article
Insulin, Insulin-like Growth Factor-I, and Platelet-Derived Growth Factor Activate Extracellular Signal-Regulated Kinase by Distinct Pathways in Muscle Cells Academic Article
Insulin- and Obesity-Related Variables in Early-Stage Breast Cancer: Correlations and Time Course of Prognostic Associations Academic Article
Insulin-Lowering Effects of Metformin in Women with Early Breast Cancer Academic Article
Insulin-like growth factor binding proteins 1 and 3 and breast cancer outcomes Academic Article
Insulin-resistant patients with type 2 diabetes mellitus have higher serum leptin levels independently of body fat mass Academic Article
Insulin-sparing effect of hydroxychloroquine in diabetic rats is concentration dependent Academic Article
Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response Academic Article
Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data Academic Article
Intensive versus Conventional Glucose Control in Critically Ill Patients Academic Article
Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study Academic Article
Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase Academic Article
Interleukin-6 and its mRNA responses in exercise and recovery: relationship to muscle glycogen Academic Article
Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins Academic Article
Intraclass Correlations Among Physiologic Measures in Children and Adolescents Academic Article
Involvement of the actin network in insulin signalling. Conference Paper
Is Glutamate Decarboxylase 2 (GAD2) a Genetic Link between Low Birth Weight and Subsequent Development of Obesity in Children? Academic Article
Is Leptin a Mediator of Adverse Prognostic Effects of Obesity in Breast Cancer? Academic Article
Is there an effect of intranasal insulin on development and behaviour in Phelan-McDermid syndrome? A randomized, double-blind, placebo-controlled trial Academic Article
Islet xenotransplantation clinical trial: does histology show islet cells? Academic Article
Just HIT it! A time-efficient exercise strategy to improve muscle insulin sensitivity Academic Article
Lack of Hormonal Effects of a Single Dose of Nifedipine in Healthy Young Me Academic Article
Leucine supplementation enhances integrative myofibrillar protein synthesis in free-living older men consuming lower- and higher-protein diets: a parallel-group crossover study Academic Article
Leucine supplementation of a low-protein mixed macronutrient beverage enhances myofibrillar protein synthesis in young men: a double-blind, randomized trial Academic Article
Limitation of Myocardial Infarct Size Present Status Academic Article
Lithium effects on neuroendocrine function Academic Article
Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity1 Academic Article
Long term growth of factor-producing lymphoid and myeloid cells in serum-free medium. Academic Article
Low PAI-1 activity in relation to inflammatory parameters, insulin profile and body mass index Academic Article
Low muscle glycogen concentration does not suppress the anabolic response to resistance exercise Academic Article
Lowering of Glucose in Critical care: a randomized pilot trial Academic Article
Macrophage Deletion of SOCS1 Increases Sensitivity to LPS and Palmitic Acid and Results in Systemic Inflammation and Hepatic Insulin Resistance Academic Article
Management of patients with acute hyperkalemia Academic Article
Maternal Fructose Intake during Pregnancy and Lactation Alters Placental Growth and Leads to Sex-Specific Changes in Fetal and Neonatal Endocrine Function Academic Article
Maternal and Pregnancy Related Predictors of Cardiometabolic Traits in Newborns Academic Article
Maternal antioxidants prevent β-cell apoptosis and promote formation of dual hormone-expressing endocrine cells in male offspring following fetal and neonatal nicotine exposure Academic Article
Maternal exposure to Δ9-tetrahydrocannabinol impairs female offspring glucose homeostasis and endocrine pancreatic development in the rat Academic Article
Measured creatinine clearance from timed urine collections substantially overestimates glomerular filtration rate in patients with liver cirrhosis: a systematic review and individual patient meta-analysis Academic Article
Measurement of whole body nitrogen in living man by neutron activation analysis. Academic Article
Mechanism of action of diabetogenic zinc-chelating agents. Model system studies. Academic Article
Metabolic effects of dietary lactose in adult female rats Academic Article
Metabolic, stress, and inflammatory biomarker responses to glucose administration in Fischer-344 rats: intraperitoneal vs. oral delivery Academic Article
Metformin in adults with type 1 diabetes: Design and methods of REducing with MetfOrmin Vascular Adverse Lesions (REMOVAL): An international multicentre trial Academic Article
Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss Academic Article
Micronutrients impact the gut microbiota and blood glucose Academic Article
Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young men Academic Article
Modulation of insulin action by vanadate: evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling Academic Article
Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans Academic Article
Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic responses in men Academic Article
Myofibrillar and collagen protein synthesis in human skeletal muscle in young men after maximal shortening and lengthening contractions Academic Article
Myostatin inhibition therapy for insulin-deficient type 1 diabetes Academic Article
NOD2 Activation Induces Muscle Cell-Autonomous Innate Immune Responses and Insulin Resistance Academic Article
Neuroendocrine Responses As an Indicator of Recurrence Liability in Primary Affective Illness Academic Article
Neuroendocrine strategies in affective disorders Academic Article
Nitrate Supplementation’s Improvement of 10-km Time-Trial Performance in Trained Cyclists Academic Article
No difference in exogenous carbohydrate oxidation during exercise in children with and without impaired glucose tolerance Academic Article
Nutrient Sensing and Response Drive Developmental Progression in Caenorhabditis elegans Academic Article
Nutritional Strategies to Promote Postexercise Recovery Academic Article
Nutritional Supplementation and Resistance Exercise: What Is the Evidence for Enhanced Skeletal Muscle Hypertrophy? Academic Article
Nutritionally Complete Prepared Meal Plan to Reduce Cardiovascular Risk Factors Academic Article
Oligomeric resistin impairs insulin and AICAR-stimulated glucose uptake in mouse skeletal muscle by inhibiting GLUT4 translocation Academic Article
Optimisation of media for the culture of normal human epithelial cells from oesophageal mucosa Academic Article
Optimizing electrostatic interactions for controlling the release of proteins from anionic and cationically modified alginate Academic Article
PGC‐1α gene expression is down‐regulated by Akt‐mediated phosphorylation and nuclear exclusion of FoxO1 in insulin‐stimulated skeletal muscle Academic Article
PIKfyve: a new fish in the growing pool of AMPK substrates Academic Article
Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans Academic Article
Palmitate- and lipopolysaccharide-activated macrophages evoke contrasting insulin responses in muscle cells Academic Article
Passively Operated Microfluidic Device for Stimulation and Secretion Sampling of Single Pancreatic Islets Academic Article
Patient Values and Preferences Regarding Continuous Subcutaneous Insulin Infusion and Artificial Pancreas in Adults with Type 1 Diabetes: A Systematic Review of Quantitative and Qualitative Data Academic Article
Peripheral and central regulation of insulin by the intestine and microbiome Academic Article
Personalized pharmacotherapy in diabetes care using clinical pharmacology data of basal insulin analogues Academic Article
Phosphatidylinositol 3-kinase and the actin network are not required for the stimulation of glucose transport caused by mitochondrial uncoupling: comparison with insulin action Academic Article
Physiological Relationships Between Growth Hormone Level, Glycemia and Metabolic Control in Dogs Academic Article
Pilot study of the accuracy of bedside glucometry in the intensive care unit Academic Article
Piloting a Novel Algorithm for Glucose Control in the Coronary Care Unit: The RECREATE (REsearching Coronary REduction by Appropriately Targeting Euglycemia) trial Academic Article
Prediagnostic levels of C-peptide, IGF-I, IGFBP -1, -2 and -3 and risk of endometrial cancer Academic Article
Preparation and Evaluation of Fluorine-18-Labeled Insulin as a Molecular Imaging Probe for Studying Insulin Receptor Expression in Tumors Academic Article
Prevalence and determinants of microalbuminuria in high-risk diabetic and nondiabetic patients in the Heart Outcomes Prevention Evaluation Study. The HOPE Study Investigators. Academic Article
Problems of stopping trials early Academic Article
Prolactin response to hypoglycemia in acute depression Academic Article
Prospective Associations of Vitamin D With β-Cell Function and Glycemia Academic Article
Protein leucine content is a determinant of shorter- and longer-term muscle protein synthetic responses at rest and following resistance exercise in healthy older women: a randomized, controlled trial Academic Article
Protein–Leucine Fed Dose Effects on Muscle Protein Synthesis after Endurance Exercise Academic Article
Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet Academic Article
RE: "SERUM INSULIN AND GLUCOSE LEVELS AND BREAST CANCER INCIDENCE: THE ATHEROSCLEROSIS RISK IN COMMUNITIES STUDY" Academic Article
REDUCTION OF CIRCULATING INSULIN LEVELS DURING THE INFUSION OF DIFFERENT PROSTAGLANDINS IN THE RAT Academic Article
RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice Academic Article
Randomized Trial of Tamoxifen Versus Combined Tamoxifen and Octreotide LAR Therapy in the Adjuvant Treatment of Early-Stage Breast Cancer in Postmenopausal Women: NCIC CTG MA.14 Academic Article
Randomized Trials in Critical Care Nutrition Academic Article
Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling Academic Article
Rapid exercise-induced changes in PGC-1α mRNA and protein in human skeletal muscle Academic Article
Rapid repression of quiescence-specific gene expression by epidermal growth factor, insulin, and pp60v-src. Academic Article
Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention) Academic Article
Reduced Fat Oxidation Rates During Submaximal Exercise in Adolescents with Crohnʼs Disease Academic Article
Reduced Socs3 expression in adipose tissue protects female mice against obesity-induced insulin resistance Academic Article
Reduced fat oxidation rates during submaximal exercise in boys with cystic fibrosis Academic Article
Reduced skeletal muscle AMPK and mitochondrial markers do not promote age-induced insulin resistance Academic Article
Regulation of glucose transporter 4 traffic by energy deprivation from mitochondrial compromise Academic Article
Relationship between Escherichia coli O157:H7 and diabetes mellitus Conference Paper
Relationship of glucose and insulin levels to the risk of myocardial infarction: a case-control study Academic Article
Relationship of phospholipid hexagonal phases to biological phenomena Academic Article
Relationships of iron metabolism with insulin resistance and glucose levels in young and healthy adults Academic Article
Reliability of serum hormones in premenopausal and postmenopausal women over a one-year period. Academic Article
Repeated maternal glucocorticoid administration and the developing liver in fetal sheep Academic Article
Resistance exercise decreases eIF2Bε phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men Academic Article
Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men Academic Article
Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men Academic Article
Resistance training alters the response of fed state mixed muscle protein synthesis in young men Academic Article
Risk factors for acute myocardial infarction in Indians: a case-control study Academic Article
Role of Glucagon in the Glucoregulatory Response to Insulin-Induced Hypoglycemia in the Rat Academic Article
Role of the actin cytoskeleton in insulin action Academic Article
SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control Academic Article
Serum Lipids and Outcome of Early-stage Breast Cancer: Results of a Prospective Cohort Study Academic Article
Serum adiponectin is related to plasma high-density lipoprotein cholesterol but not to plasma insulin-concentration in healthy children: the FLVS II study Academic Article
Sevoflurane-induced hyperglycemia is attenuated by salsalate in obese insulin-resistant mice Academic Article
Sex-Specific Differences in an ApoE−/−:Ins2+/Akita Mouse Model of Accelerated Atherosclerosis Academic Article
Short Leg Length, a Marker of Early Childhood Deprivation, Is Associated With Metabolic Disorders Underlying Type 2 Diabetes: The PROMISE cohort study Academic Article
Short‐term intensive insulin as induction and maintenance therapy for the preservation of beta‐cell function in early type 2 diabetes ( RESET‐IT Main ): A 2‐year randomized controlled trial Academic Article
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin Academic Article
Socs1 Deficiency Enhances Hepatic Insulin Signaling Academic Article
Somatostatin: alterations in the central nervous system in neurological diseases. Academic Article
Some peculiarities of the glucoregulatory response to glucose infusion in the rat Academic Article
State of metabolic control determines role of epinephrine-glucagon interaction in glucoregulation in diabetes Academic Article
Statins Promote Interleukin-1β–Dependent Adipocyte Insulin Resistance Through Lower Prenylation, Not Cholesterol Academic Article
Statins activate the NLRP3 inflammasome and impair insulin signaling via p38 and mTOR Academic Article
Studies on the mechanism underlying the influence of alanine infusion on glucose dynamics in the dog. Academic Article
Substrate Turnover and Oxidation During Moderate-Intensity Exercise Following Acute Plasma Volume Expansion Academic Article
Substrate utilization during exercise with glucose and glucose plus fructose ingestion in boys ages 10–14 yr Academic Article
Substrate utilization in boys during exercise with [ 13 C]-glucose ingestion Academic Article
Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in men Academic Article
Surface Denaturation and Amyloid Fibril Formation of Insulin at Model Lipid−Water Interfaces Academic Article
Synthesis and Characterization of Rhenium and Technetium-99m Labeled Insulin Academic Article
Synthesis and in Vitro Evaluation of 18F- and 19F-Labeled Insulin: A New Radiotracer for PET-based Molecular Imaging Studies Academic Article
THE EARLY DETECTION OF DYSTROPHIA MYOTONICA Academic Article
TNF, but not hyperinsulinemia or hyperglycemia, is a key driver of obesity‐induced monocytosis revealing that inflammatory monocytes correlate with insulin in obese male mice Academic Article
Targeting macrophage scavenger receptor 1 promotes insulin resistance in obese male mice Academic Article
Tennis anyone? The lungs as a new court for systemic therapy. Academic Article
The Association of Serum Sialic Acid with Carotid Intima-Media Thickness and Anthropometric and Metabolic Parameters in Obese Children and Adolescents Academic Article
The Economic Value of a New Insulin Preparation, Humalog?? Mix 25??? Academic Article
The Effect of Ginseng (The Genus Panax) on Glycemic Control: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials Academic Article
The Influence of Post-exercise Macronutrient Intake on Energy Balance and Protein Metabolism in Active Females Participating in Endurance Training Academic Article
The Insulin-Mimetic Agent Vanadate Promotes Receptor Endocytosis and Inhibits Intracellular Ligand-Receptor Degradation by a Mechanism Distinct From the Lysosomotropic Agents Academic Article
The JDRF CCTN CGM TIME Trial: Timing of Initiation of continuous glucose Monitoring in Established pediatric type 1 diabetes: study protocol, recruitment and baseline characteristics Academic Article
The Q121 Variant of ENPP1 May Protect From Childhood Overweight/obesity in the Italian Population Academic Article
The Stimulatory Effect of Globular Adiponectin on Insulin-Stimulated Glucose Uptake and Fatty Acid Oxidation Is Impaired in Skeletal Muscle From Obese Subjects Academic Article
The association of basal insulin treatment versus standard care with outcomes in anti-GAD positive and negative subjects: A post-hoc analysis of the ORIGIN trial Academic Article
The carotid bodies influence growth responses to moderate maternal undernutrition in late-gestation fetal sheep Academic Article
The effect of adding metformin to insulin therapy for type 1 diabetes mellitus children: A systematic review and meta-analysis Academic Article
The effect of continuous enteral nutrition on gastric acidity in humans Academic Article
The effect of glucagon antibodies on plasma glucose and insulin levels Academic Article
The effect of smoking cessation pharmacotherapies on pancreatic beta cell function Academic Article
The effects of exercise training on insulin resistance in patients with coronary artery disease Academic Article
The effects of various diets on glycemic outcomes during pregnancy: A systematic review and network meta-analysis Academic Article
The efficacy and safety of glucose control algorithms in intensive care: a pilot study of the Survival Using Glucose Algorithm Regulation (SUGAR) trial Academic Article
The fatty acid transporter FAT/CD36 is upregulated in subcutaneous and visceral adipose tissues in human obesity and type 2 diabetes Academic Article
The impact of bariatric surgery on insulin-treated type 2 diabetes patients Academic Article
The integrative role of leptin, oestrogen and the insulin family in obesity‐associated breast cancer: potential effects of exercise Academic Article
The liver plasma membrane Ca2+ pump: Hormonal sensitivity Academic Article
The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity Academic Article
The study of spontaneous GH secretion after 36-h fasting distinguishes between GH-deficient and normal adults Academic Article
TheINSVNTR Locus Does Not Associate with Smallness for Gestational Age (SGA) but Interacts with SGA to Increase Insulin Resistance in Young Adults Academic Article
Theophylline Stimulation of Gluconeogenesis from Alanine in Normal and Sympathectomized Rats Academic Article
Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis Academic Article
Tissue-Specific Role of Glycogen Synthase Kinase 3β in Glucose Homeostasis and Insulin Action Academic Article
Transalveolar Metabolic Protection to the Lung Academic Article
Transcriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein Academic Article
Transgenerational effects of fetal and neonatal exposure to nicotine Academic Article
Treatment satisfaction and quality of life using an early insulinization strategy with insulin glargine compared to an adjusted oral therapy in the management of Type 2 diabetes: The Canadian INSIGHT Study Academic Article
Trends in selection and timing of first‐line pharmacotherapy in older patients with Type 2 diabetes diagnosed between 1994 and 2006 Academic Article
Troglitazone monotherapy improves glycemic control in patients with type 2 diabetes mellitus: a randomized, controlled study. The Troglitazone Study Group. Academic Article
Turnover and precursor-product relationships of nonlipid metabolites. Academic Article
Use of Inhaled Insulin in a Basal/Bolus Insulin Regimen in Type 1 Diabetic Subjects: A 6-month, randomized, comparative trial Academic Article
Using WinBUGS to Fit Nonlinear Mixed Models with an Application to Pharmacokinetic Modelling of Insulin Response to Glucose Challenge in Sheep Exposed Antenatally to Glucocorticoids Academic Article
Vaccenic acid in serum triglycerides is associated with markers of insulin resistance in men Academic Article
[Location of an insulinoma by transhepatic phlebography with staged insulin assays (author's transl)]. Academic Article
[The glycoregulatory response to glucagon and epinephrine infusions in chronic uremia]. Academic Article
“A Spoonful of sugar” — Trans-alveolar nutrition Academic Article

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