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Therapeutic Ultrasound-Induced Insulin Release in...
Journal article

Therapeutic Ultrasound-Induced Insulin Release in Vivo

Abstract

The tolerability and efficacy of low-frequency, low-intensity therapeutic ultrasound-induced insulin release was investigated in a pre-clinical in vivo murine model. The treatment groups received a single 5-min continuous sonication at 1 MHz and 1.0 W/cm2. Insulin and glucagon levels in the serum were determined using enzyme-linked immunosorbent assay. The pancreas was excised and sectioned for histologic analysis. In terminal studies, we …

Authors

Singh T; Suarez Castellanos I; Bhowmick DC; Cohen J; Jeremic A; Zderic V

Journal

Ultrasound in Medicine & Biology, Vol. 46, No. 3, pp. 639–648

Publisher

Elsevier

Publication Date

March 2020

DOI

10.1016/j.ultrasmedbio.2019.10.022

ISSN

0301-5629