Rapid repression of quiescence-specific gene expression by epidermal growth factor, insulin, and pp60v-src. Academic Article uri icon

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abstract

  • We isolated a cDNA for p20K, a secreted protein preferentially synthesized in nonproliferating cells. p20K mRNA and protein levels declined rapidly following treatment with various mitogens. DNA sequence analysis of the p20K cDNA predicted a novel protein distantly related to alpha 2 mu-globulin and plasma retinol-binding protein.

publication date

  • March 1989