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Rapid Repression of Quiescence-Specific Gene...
Journal article

Rapid Repression of Quiescence-Specific Gene Expression by Epidermal Growth Factor, Insulin, and pp60v-src

Abstract

We isolated a cDNA for p20K, a secreted protein preferentially synthesized in nonproliferating cells. p20K mRNA and protein levels declined rapidly following treatment with various mitogens. DNA sequence analysis of the p20K cDNA predicted a novel protein distantly related to α2μ-globulin and plasma retinol-binding protein.

Authors

Bedard P-A; Yannoni Y; Simmons DL; Erikson RL

Journal

Molecular and Cellular Biology, Vol. 9, No. 3, pp. 1371–1375

Publisher

Taylor & Francis

Publication Date

March 1, 1989

DOI

10.1128/mcb.9.3.1371-1375.1989

ISSN

0270-7306