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Glucose Control in Severely Burned Patients Using...
Journal article

Glucose Control in Severely Burned Patients Using Metformin

Abstract

OBJECTIVE: To determine whether metformin can achieve glucose control no worse than insulin (noninferiority) without the danger of hypoglycemia (superiority). In addition, to assess whether metformin has any additional effects on lipolysis and inflammation that will enhance burn recovery (superiority). SUMMARY BACKGROUND DATA: Hyperglycemia and insulin resistance after burn injury are associated with increased morbidity and mortality. Insulin …

Authors

Jeschke MG; Abdullahi A; Burnett M; Rehou S; Stanojcic M

Journal

Annals of Surgery, Vol. 264, No. 3, pp. 518–527

Publisher

Wolters Kluwer

Publication Date

September 2016

DOI

10.1097/sla.0000000000001845

ISSN

0003-4932