Journal article
Effect of intensive therapy on early macrovascular disease in young individuals with type 1 diabetes. A systematic review and meta-analysis.
Abstract
OBJECTIVE: We conducted a systematic review of randomized controlled trials (RCTs) of intensive insulin therapy (IIT) in type 1 diabetes to determine the effect on macrovascular complications.
RESEARCH DESIGN AND METHODS: MEDLINE (1966-1996), Citation Index, reference lists, and personal files were used to identify RCTs of > 2 years' duration comparing IIT to conventional therapy (CT) in type 1 diabetes. Two independent reviewers applied …
Authors
Lawson ML; Gerstein HC; Tsui E; Zinman B
Journal
Diabetes Care, Vol. 22 Suppl 2, , pp. b35–b39
Publication Date
March 1999
ISSN
0149-5992