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A Systematic Review and Meta-Analysis of...
Journal article

A Systematic Review and Meta-Analysis of Hypoglycemia and Cardiovascular Events A comparison of glyburide with other secretagogues and with insulin

Abstract

OBJECTIVE: Glyburide is the most widely used sulfonylurea but has unique pharmacodynamic properties that may increase harm. We hypothesized that glyburide causes more hypoglycemia and cardiovascular events than other secretagogues or insulin. RESEARCH DESIGN AND METHODS: Data sources were Medline, Embase, Cochrane, and three other web-based clinical trial registers (1966-2005). Parallel, randomized, controlled trials in people with type 2 …

Authors

Gangji AS; Cukierman T; Gerstein HC; Goldsmith CH; Clase CM

Journal

Diabetes Care, Vol. 30, No. 2, pp. 389–394

Publisher

American Diabetes Association

Publication Date

February 1, 2007

DOI

10.2337/dc06-1789

ISSN

0149-5992