Vaccenic acid in serum triglycerides is associated with markers of insulin resistance in men Academic Article uri icon

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abstract

  • Serum triglyceride levels are associated with metabolic disorders; however, it remains unclear whether the fatty acid (FA) composition of triglycerides is also changed. Although there were no differences in circulating triglyceride levels between normoglycaemic-normoinsulinaemic and hyperglycaemic-hyperinsulinaemic men, inspection of individual FA revealed that vaccenic acid was enriched with hyperglycaemia-hyperinsulinaemia. Moreover, vaccenic acid levels were positively correlated with insulin and HOMA-IR. This reinforces that examination of individual FA in the context of insulin resistance is warranted.

authors

  • Zulyniak, Michael A
  • Ralston, Jessica C
  • Tucker, Amy J
  • MacKay, Kathy A
  • Hillyer, Lyn M
  • McNicholas, Paul
  • Graham, Terry E
  • Robinson, Lindsay E
  • Duncan, Alison M
  • Ma, David WL
  • Mutch, David M

publication date

  • October 2012