Genetic Therapy
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A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells Academic Article
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A Novel Approach to Tumor Suppression with Microencapsulated Recombinant Cells Academic Article
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A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada Academic Article
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A multiprong approach to cancer gene therapy by coencapsulated cells Academic Article
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A phase I trial of adenovector-mediated delivery of interleukin-2 (AdIL-2) in high-risk localized prostate cancer Academic Article
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AAV-mediated expression of 3TSR inhibits tumor and metastatic lesion development and extends survival in a murine model of epithelial ovarian carcinoma Academic Article
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Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque Academic Article
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Adenovector engineered interleukin-2 expressing autologous plasma cell vaccination after high-dose chemotherapy for multiple myeloma - a phase 1 study Academic Article
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Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial Academic Article
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Adenoviral Vector Expressing Murine Angiostatin Inhibits a Model of Breast Cancer Metastatic Growth in the Lungs of Mice Academic Article
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Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models Academic Article
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Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia Academic Article
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Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat Academic Article
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Adenovirus vectors for human gene therapy Academic Article
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Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans Academic Article
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Adjunctive β2‐agonists reverse neuromuscular involvement in murine Pompe disease Academic Article
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Advances in Thrombosis and Hemostasis Academic Article
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Aerosol drug delivery: developments in device design and clinical use Academic Article
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Antiangiogenic and Antifibrotic Gene Therapy in a Chronic Infusion Model of Peritoneal Dialysis in Rats Academic Article
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Attenuation of the Glucocorticoid Response during Ad5IL-12 Adenovirus Vector Treatment Enhances Natural Killer Cell–Mediated Killing of MHC Class I–Negative LNCaP Prostate Tumors Academic Article
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Autologous fibroblast implantation. Feasibility and potential problems in gene replacement therapy. Academic Article
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BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis Academic Article
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Biological Therapies for Atrial Fibrillation Academic Article
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Biological properties of photocrosslinked alginate microcapsules Academic Article
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Blood outgrowth endothelial cells overexpressing eNOS mitigate pulmonary hypertension in rats: a unique carrier cell enabling autologous cell-based gene therapy Academic Article
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Brown Norway Chromosome 13 Confers Protection From High Salt to Consomic Dahl S Rat Academic Article
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Budesonide Enhances Repeated Gene Transfer and Expression in the Lung with Adenoviral Vectors Academic Article
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Canine models for human genetic neurodegenerative diseases Academic Article
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Carrier Cell-based Delivery of an Oncolytic Virus Circumvents Antiviral Immunity Academic Article
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Cell Phones and Landlines: The Impact of Gene Therapy on the Cost and Availability of Treatment for Hemophilia Academic Article
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Cell-based cancer gene therapy: breaking tolerance or inducing autoimmunity? Academic Article
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Cell-matrix Interactions of Factor IX (FIX)-engineered human mesenchymal stromal cells encapsulated in RGD-alginate vs. Fibrinogen-alginate microcapsules Academic Article
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Circulating hematopoietic stem cells serve as novel targets for in utero gene therapy. Academic Article
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Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer Academic Article
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Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer Academic Article
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Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity Academic Article
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Combined Immunotherapy and Antiangiogenic Therapy of Cancer with Microencapsulated Cells Academic Article
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Comparative evaluation of IGF-I gene transfer and IGF-I protein administration for enhancing skeletal muscle regeneration after injury Academic Article
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Construction of First-Generation Adenoviral Vectors Academic Article
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Construction of a Double Recombinant Adenovirus Vector Expressing a Heterodimeric Cytokine:In VitroandIn VivoProduction of Biologically Active Interleukin-12 Academic Article
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Core data set on safety, efficacy, and durability of hemophilia gene therapy for a global registry: Communication from the SSC of the ISTH Academic Article
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Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project Academic Article
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Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors Academic Article
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Correction of the Growth Defect in Dwarf Mice with Nonautologous Microencapsulated Myoblasts—An Alternate Approach to Somatic Gene Therapy Academic Article
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Critical Interactions between Immunogenic Cancer Cell Death, Oncolytic Viruses, and the Immune System Define the Rational Design of Combination Immunotherapies Academic Article
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Cytokine Therapeutics for Asthma: An Appraisal of Current Evidence and Future Prospects Academic Article
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DEVELOPMENT OF PROSTATE-SPECIFIC ANTIGEN PROMOTER-BASED GENE THERAPY FOR ANDROGEN-INDEPENDENT HUMAN PROSTATE CANCER Academic Article
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DNAzymes: From Creation In Vitro to Application In Vivo Academic Article
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Delivery of Recombinant Gene Products with Microencapsulated Cells In Vivo Academic Article
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Delivery of a Secretable Adenosine Deaminase Through Microcapsules–A Novel Approach to Somatic Gene Therapy Academic Article
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Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B Academic Article
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Delivery of recombinant gene product to canine brain with the use of microencapsulation Academic Article
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Delivery of recombinant product from subcutaneous implants of encapsulated recombinant cells in canines Academic Article
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Development of a FLP/frt System for Generating Helper-Dependent Adenoviral Vectors Academic Article
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Development of a bovine adenovirus type 3-based expression vector Academic Article
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Development of a size-restricted pIX-deleted helper virus for amplification of helper-dependent adenovirus vectors Academic Article
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Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12 Academic Article
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Efficacy of gene-therapy based on adenovirus encoding granulocyte-macrophage colony-stimulating factor in drug-sensitive and drug-resistant experimental pulmonary tuberculosis Academic Article
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Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines Academic Article
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Encapsulated engineered myoblasts can cure Hurler syndrome: preclinical experiments in the mouse model Academic Article
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Encapsulation for Somatic Gene Therapy Conference Paper
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Encapsulation of Recombinant Cells with a Novel Magnetized Alginate for Magnetic Resonance Imaging Academic Article
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Enhancement of myoblast microencapsulation for gene therapy Academic Article
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Epigenetic therapy inhibits metastases by disrupting premetastatic niches Academic Article
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Establishing the appropriate primary endpoint in haemophilia gene therapy pivotal studies Academic Article
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Evolution of haemophilia integrated care in the era of gene therapy: Treatment centre’s readiness in United States and EU Academic Article
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Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity Academic Article
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Expression of Human Factor IX by Microencapsulated Recombinant Fibroblasts Academic Article
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Expression of exogenous wt-p53 does not affect normal hematopoiesis: implications for bone marrow purging Academic Article
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Factors influencing therapeutic efficacy and the host immune response to helper‐dependent adenoviral gene therapy in hemophilia A mice Academic Article
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Foreign Gene Expression by Human Adenovirus Type 5-Based Vectors Studied Using Firefly Luciferase and Bacterial β-Galactosidase Genes as Reporters Academic Article
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Gene Therapy for Hemophilia Academic Article
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Gene Therapy for Hemophilia: Addressing the Coming Challenges of Affordability and Accessibility Academic Article
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Gene Therapy for Pulmonary Diseases Academic Article
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Gene Therapy, A Targeted Treatment for Diabetic Nephropathy Academic Article
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Gene Therapy: Socioeconomic and Ethical Issues A Roundtable Discussion Academic Article
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Gene Transfer of Matrix Metalloproteinase-9 Induces Tumor Regression of Breast Cancer In vivo Academic Article
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Gene therapy for murine mucopolysaccharidosis type VII Conference Paper
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Gene therapy to cure haemophilia: Is robust scientific inquiry the missing factor? Academic Article
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Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity Academic Article
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Getting oncolytic virus therapies off the ground Academic Article
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Growth Retardation—An Unexpected Outcome from Growth Hormone Gene Therapy in Normal Mice with Microencapsulated Myoblasts Academic Article
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Harnessing Oncolytic Virus-mediated Antitumor Immunity in an Infected Cell Vaccine Academic Article
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Have advanced research technologies made real impact on respiratory medicine? Academic Article
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Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A Academic Article
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Hepatocyte Targeting with Gd-EOB-DTPA Academic Article
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Herpes simplex virus type-1 infection upregulates cellular promoters and telomerase activity in both tumor and nontumor human cells Academic Article
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Heterogeneity of the immune response to adenovirus-mediated factor VIII gene therapy in different inbred hemophilic mouse strains Academic Article
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Highly Priced Gene Therapies: A Wake-Up Call for Early Price Regulation Academic Article
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Human Adenovirus Vectors for Gene Transfer into Mammalian Cells Academic Article
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Human Gene Marker/Therapy Clincal Protocols (Complete Updated Listings) Academic Article
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IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization Academic Article
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IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion Academic Article
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Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy Academic Article
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Imaging Transgene Activity In vivo Academic Article
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Immuno-Isolation in Cancer Gene Therapy Academic Article
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Immuno-Isolation in Oncology - A Mini-Review Academic Article
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Immuno-gene therapy approaches for cancer: from in vitro studies to clinical trials Academic Article
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Immuno-gene therapy of established prostate tumors using chimeric receptor-redirected human lymphocytes. Academic Article
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Immunotherapeutic effects of recombinant adenovirus encoding granulocyte–macrophage colony-stimulating factor in experimental pulmonary tuberculosis Academic Article
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Immunotherapeutic effects of recombinant adenovirus encoding interleukin 12 in experimental pulmonary tuberculosis Academic Article
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Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer Academic Article
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In Vivo Adenoviral-Mediated Gene Transfer of Interleukin-2 in Cutaneous Plasmacytoma Academic Article
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In vitro correction of iduronate-2-sulfatase deficiency by adenovirus-mediated gene transfer Academic Article
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In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors. Academic Article
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Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12 Academic Article
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Inhibition of intimal hyperplasia after stenting by over-expression of p15: A member of the INK4 family of cyclin-dependent kinase inhibitors Academic Article
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Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression Academic Article
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Intramarrow Cytokine Gene Transfer by Adenoviral Vectors in Dogs Academic Article
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Intrathymic implants of genetically modified fibroblasts Academic Article
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Intratumoral administration of an adenovirus expressing a kinase dead form of ErbB-2 inhibits tumor growth Academic Article
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Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors Academic Article
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Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model. Academic Article
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Lentivirus-mediated gene therapy for Fabry disease Academic Article
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Leukemia targeting ligands isolated from phage display peptide libraries Academic Article
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Luciferase Therapeutic Microcapsules for Gene Therapy Academic Article
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Macrophage inflammatory protein-2 gene therapy attenuates adenovirus- and acetaminophen-mediated hepatic injury Academic Article
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Mechanically enhanced microcapsules for cellular gene therapy Academic Article
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MicroRNA-145 Targeted Therapy Reduces Atherosclerosis Conference Paper
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Microcapsules as Bio-organs for Somatic Gene Therapya Conference Paper
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Microencapsulation — An alternative approach to gene therapy Conference Paper
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Modifier Gene Studies to Identify New Therapeutic Targets in Cystic Fibrosis Academic Article
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Monkey business for hemophilia management Academic Article
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Murine dendritic cells transduced with an adenoviral vector expressing a defined tumor antigen can overcome anti-adenovirus neutralizing immunity and induce effective tumor regression. Academic Article
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Myostatin inhibition therapy for insulin-deficient type 1 diabetes Academic Article
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Nervous system modification by transplants and gene transfer Academic Article
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Non-Autologous Transplantation with Immuno-isolation in Large Animals-A Review Conference Paper
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Non-viral transfer approaches for the gene therapy of mucopolysaccharidosis type II (Hunter syndrome) Conference Paper
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Nonautologous gene therapy with implantable devices Academic Article
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Nonviral Gene Therapy Approaches to Hemophilia Academic Article
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Novel targets and approaches in advanced prostate cancer Academic Article
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Novel therapy for asthma Academic Article
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NovelLPLmutations associated with lipoprotein lipase deficiency: two case reports and a literature review Academic Article
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ORFV: A Novel Oncolytic and Immune Stimulating Parapoxvirus Therapeutic Academic Article
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Oncolytic Viruses: Therapeutics With an Identity Crisis Academic Article
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One-step preparation of gold nanovectors using folate modified polyethylenimine and their use in target-specific gene transfection Academic Article
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Optimizing Plasmid-Based Gene Transfer for Investigating Skeletal Muscle Structure and Function Academic Article
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Overview of phase I studies of intravenous administration of PV701, an oncolytic virus. Academic Article
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Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes Academic Article
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Patient preferences and priorities for haemophilia gene therapy in the US: A discrete choice experiment Academic Article
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Patient selection may affect gene therapy success. Dominant negative effects observed for ornithine transcarbamylase in mouse and human hepatocytes. Academic Article
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Persistent Delivery of Factor IX in Mice: Gene Therapy for Hemophilia Using Implantable Microcapsules Academic Article
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Phage-Mediated Gene Therapy Academic Article
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Pharmacotherapy for erectile dysfunction Academic Article
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Pluripotent human stem cell lines: what we can learn about cancer initiation Academic Article
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Preparation of Helper-Dependent Adenoviral Vectors Academic Article
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Programmable insect cell carriers for systemic delivery of integrated cancer biotherapy Academic Article
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Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein Academic Article
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RNA-polymerase III-driven expression cassettes in human gene therapy. Academic Article
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Recognition of Virus Infection and Innate Host Responses to Viral Gene Therapy Vectors Academic Article
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Reduced tissue macrophage population in the lung by anticancer agent cyclophosphamide: restoration by local granulocyte macrophage–colony-stimulating factor gene transfer Academic Article
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Repeated oral administration of chitosan/DNA nanoparticles delivers functional FVIII with the absence of antibodies in hemophilia A mice Academic Article
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Retroviral Transduction of Hematopoietic Progenitors Derived From Human Embryonic Stem Cells Academic Article
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Retroviral expression of MIR2 decreases both surface MHC class I and the alloimmune CTL response Academic Article
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Review‐The Use of Immunosuppressive Agents to Prevent Neutralizing Antibodies Against a Transgene Product Academic Article
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Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits Academic Article
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Sensitivity of 5-fluorouracil-resistant cancer cells to adenovirus suicide gene therapy Academic Article
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Somatic Gene Therapy for a Neurodegenerative Disease Using Microencapsulated Recombinant Cells Academic Article
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Strategies to Enhance Viral Penetration of Solid Tumors Academic Article
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Suppression of Immunological Response Against a Transgene Product Delivered from Microencapsulated Cells Academic Article
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Suppression of immunological response against a novel gene product delivered by implants of genetically modified fibroblasts. Academic Article
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Sustained and therapeutic delivery of factor IX in nude haemophilia B mice by encapsulated C2C12 myoblasts: concurrent tumourigenesis Academic Article
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Sustained and therapeutic levels of human factor IX in hemophilia B mice implanted with microcapsules: key role of encapsulated cells Academic Article
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Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing Academic Article
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Telomerase Mediates Vascular Endothelial Growth Factor-dependent Responsiveness in a Rat Model of Hind Limb Ischemia Academic Article
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The 1st
WFH
Gene Therapy Round Table: Understanding the landscape and challenges of gene therapy for haemophilia around the world Academic Article
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The Future of Pain Management in Emergency Medicine Academic Article
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The efficacy of electroporated plasmid vaccines correlates with long-term antigen production in vivo Academic Article
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The establishment of murine blood outgrowth endothelial cells and observations relevant to gene therapy Academic Article
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The human SCGB2A2 (Mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not in normal nonmammary cells Academic Article
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The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma Academic Article
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The use of adenoviral vectors for gene therapy and gene transfer in vivo Academic Article
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Therapeutic Arteriogenesis by Ultrasound-Mediated VEGF
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Plasmid Gene Delivery to Chronically Ischemic Skeletal Muscle Academic Article
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Therapeutic Effect of Angiostatin Gene Transfer in a Murine Model of Endometriosis Academic Article
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Therapeutic levels of human Factor VIII in mice implanted with encapsulated cells: potential for gene therapy of haemophilia A Academic Article
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Towards gene therapy in the nervous system. Academic Article
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Toxicity Associated with Repeated Administration of First-Generation Adenovirus Vectors Does Not Occur with a Helper-Dependent Vector Academic Article
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Transient Gene Transfer and Expression in the Lung Academic Article
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Transient Gene Transfer of IL-12 Regulates Chemokine Expression and Disease Severity in Experimental Arthritis Academic Article
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Transplanted hepatocytes infected with a complement receptor type 1 (CR1)-containing recombinant adenovirus are resistant to hyperacute rejection Academic Article
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Treatment of a Lysosomal Storage Disease, Mucopolysaccharidosis VII, with Microencapsulated Recombinant Cells Academic Article
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Treatment of hemophilia B in mice with nonautologous somatic gene therapeutics Academic Article
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Tumor Protection Following Vaccination With Low Doses of Lentivirally Transduced DCs Expressing the Self-antigen erbB2 Academic Article
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Tumor-targeting domains for chimeric antigen receptor T cells Academic Article
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Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNFα Academic Article
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Tumour therapy in mice using adenovirus vectors expressing human TNFa. Academic Article
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Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration Academic Article
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VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats Academic Article
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Vascular Repair and Regeneration as a Therapeutic Target for Pulmonary Arterial Hypertension Academic Article
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Vesicular Stomatitis Virus Oncolytic Treatment Interferes with Tumor-Associated Dendritic Cell Functions and Abrogates Tumor Antigen Presentation Academic Article
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What is a cure and how do we get there? Academic Article
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Wnt7a treatment ameliorates muscular dystrophy Academic Article
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World Federation of Hemophilia Gene Therapy Registry Academic Article
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Wt-p53 action in human leukaemia cell lines corresponding to different stages of differentiation Academic Article
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[Cure of hemophilia is approaching. Gene therapy is the hope]. Academic Article
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[Gene therapy – from idea to reality]. Academic Article