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Brown Norway Chromosome 13 Confers Protection From...
Journal article

Brown Norway Chromosome 13 Confers Protection From High Salt to Consomic Dahl S Rat

Abstract

Consomic rats (SS.BN13), in which chromosome 13 from normotensive inbred Brown Norway rats from a colony maintained at the Medical College of Wisconsin (BN/Mcw) was introgressed into the background of Dahl salt-sensitive (SS/Mcw) rats, also maintained in a colony at the Medical College of Wisconsin, were bred. The present studies determined the mean arterial pressure (MAP) responses to salt and renal and peripheral vascular …

Authors

Cowley AW; Roman RJ; Kaldunski ML; Dumas P; Dickhout JG; Greene AS; Jacob HJ

Journal

Hypertension, Vol. 37, No. 2, pp. 456–461

Publisher

Ovid Technologies (Wolters Kluwer Health)

Publication Date

February 2001

DOI

10.1161/01.hyp.37.2.456

ISSN

0194-911X

Associated Experts

Jeffrey Dickhout

Lecturer (Adjunct), Faculty of Health Sciences
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Labels

Medical Subject Headings (MeSH)

Angiotensin IIAnimalsBlood PressureFibrosisFurosemideGene Transfer TechniquesGenetic TherapyGenotypeHypertensionKidney GlomerulusKidney MedullaKidney TubulesNecrosisNorepinephrineProteinuriaRatsRats, Inbred BNRats, Inbred DahlRenal ArteryReninSclerosisSodium ChlorideSodium, DietaryVascular Resistance

Fields of Research (FoR)

3201 Cardiovascular medicine and haematology3202 Clinical sciences
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