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Mechanically enhanced microcapsules for cellular...
Journal article

Mechanically enhanced microcapsules for cellular gene therapy

Abstract

Microcapsules bearing a covalently cross-linked coating have been developed for cellular gene therapy as an improvement on alginate-poly(L-lysine)-alginate (APA) microcapsules that only have ionic cross-linking. In this study, two mutually reactive polyelectrolytes, a polycation (designated C70), poly([2-(methacryloyloxy)ethyl]trimethylammonium chloride-co-2-aminoethyl methacrylate hydrochloride) and a polyanion (designated A70), poly(sodium …

Authors

Shen F; Mazumder MAJ; Burke NAD; Stöver HDH; Potter MA

Journal

Journal of Biomedical Materials Research Part B Applied Biomaterials, Vol. 90B, No. 1, pp. 350–361

Publisher

Wiley

Publication Date

7 2009

DOI

10.1002/jbm.b.31292

ISSN

1552-4973