Journal article
Encapsulation of Recombinant Cells with a Novel Magnetized Alginate for Magnetic Resonance Imaging
Abstract
Implanting recombinant cells encapsulated in alginate microcapsules to express therapeutic proteins has been proven effective in treating several mouse models of human diseases (neurological disorders, dwarfism, hemophilia, lysosomal storage disease, and cancer). In anticipation of clinical application, we have reported the synthesis and characterization of a magnetized ferrofluid alginate that potentially allows tracking of these microcapsules …
Authors
Shen F; Li AA; Gong Y-K; Somers S; Potter MA; Winnik FM; Chang PL
Journal
Human Gene Therapy, Vol. 16, No. 8, pp. 971–984
Publisher
Mary Ann Liebert
Publication Date
August 2005
DOI
10.1089/hum.2005.16.971
ISSN
1043-0342