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Cell-matrix Interactions of Factor IX...
Journal article

Cell-matrix Interactions of Factor IX (FIX)-engineered human mesenchymal stromal cells encapsulated in RGD-alginate vs. Fibrinogen-alginate microcapsules

Abstract

The success of cell microencapsulation technology in tissue engineering and protein delivery applications depends on the viability and functionality of the encapsulated cells, which in turn are dependent upon cell/matrix interactions. In this work, we compared the viability of cord blood-derived mesenchymal stromal cells (CB MSCs), engineered to secrete factor IX (FIX) for hemophilia treatment, and encapsulated in arginine-glycine-aspartate …

Authors

Sayyar B; Dodd M; Marquez-Curtis L; Janowska-Wieczorek A; Hortelano G

Journal

Artificial Cells Nanomedicine and Biotechnology, Vol. 42, No. 2, pp. 102–109

Publisher

Taylor & Francis

Publication Date

April 2014

DOI

10.3109/21691401.2013.794354

ISSN

2169-1401