Protein Conformation Concept

subject area of

• A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function  Academic Article
• A Highly Dynamic Loop of the Pseudomonas aeruginosa PA14 Type IV Pilin Is Essential for Pilus Assembly  Academic Article
• A Novel Linear Amphipathic β-Sheet Cationic Antimicrobial Peptide with Enhanced Selectivity for Bacterial Lipids  Academic Article
• A STUDY OF THE UNFOLDING OF THE INHIBITED SUBTILISIN IN GUANIDINE HYDROCHLORIDE  Academic Article
• A Study of the Conformational Properties of Glucagon in the Presence of Glycols  Academic Article
• A Thiolate Anion Buried within the Hydrocarbon Ruler Perturbs PagP Lipid Acyl Chain Selection  Academic Article
• A broadly distributed toxin family mediates contact-dependent antagonism between gram-positive bacteria  Academic Article
• A comparison of the interaction of glucagon, human parathyroid hormone-(1-34)-peptide and calcitonin with dimyristoylphosphatidylglycerol and with dimyristoylphosphatidylcholine  Academic Article
• A conformational landscape for alginate secretion across the outer membrane ofPseudomonas aeruginosa  Academic Article
• A divergentPseudomonas aeruginosapalmitoyltransferase essential for cystic fibrosis-specific lipid A  Academic Article
• A kinetic and equilibrium study of the denaturation of aspartic proteinases from the fungi, Endothia parasitica and Mucor miehei  Academic Article
• A novel multisystem disease associated with recessive mutations in the tyrosyl-tRNA synthetase (YARS) gene  Academic Article
• A novel supersecondary structure in globular proteins comprising the collagen-like helix and β-turn  Academic Article
• A peptide derived from a tissue factor loop region functions as a tissue factor-factor VIIa antagonist  Academic Article
• A systematic approach to isomorphous replacement using a series of simple charged mercurials  Academic Article
• AMP-activated protein kinase: the current landscape for drug development  Academic Article
• ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis  Academic Article
• APPLICATION OF THE ONE-DIMENSIONAL ISING MODEL TO THE SECONDARY STRUCTURES IN GLOBULAR PROTEINS.  Academic Article
• Access and Binding of Local Anesthetics in the Closed Sodium Channel  Academic Article
• Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII  Academic Article
• Active Site Interference and Asymmetric Activation in the Chemotaxis Protein Histidine Kinase CheA  Academic Article
• Adenosine kinase and ribokinase – the RK family of proteins  Academic Article
• Adipose tissue as an endocrine organ  Academic Article
• Adsorption of thrombin from buffer and modified plasma to polystyrene resins containing sulphonate and sulphamide arginyl methyl ester groups  Academic Article
• Alignment/Phylogeny of the Papain Superfamily of Cysteine Proteases  Academic Article
• Allosteric Site Variants of Haemophilus influenzae β-Carbonic Anhydrase  Academic Article
• Allosteric linkers in cAMP signalling  Academic Article
• Amino acid sequence of bacteriorhodopsin.  Academic Article
• Aminoglycoside antibiotic phosphotransferases are also serine protein kinases  Academic Article
• Aminoglycoside antibiotics. Structures, functions, and resistance  Conference Paper
• Aminoglycoside phosphotransferases: proteins, structure, and mechanism  Academic Article
• Amphipathic helix and its relationship to the interaction of calcitonin with phospholipids  Academic Article
• An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator  Academic Article
• An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase  Academic Article
• Analysis and Parametric Optimization of1H Off-Resonance Relaxation NMR Experiments Designed to Map Polypeptide Self-Recognition and Other Noncovalent Interactions  Academic Article
• Analysis of an allosteric binding site: the nucleoside inhibitor site of phosphorylase a  Academic Article
• Analysis of inter-residue contacts reveals folding stabilizers in P-loops of potassium, sodium, and TRPV channels  Academic Article
• Antibiotic resistance is ancient  Academic Article
• Architecture of the Neuronal Nicotinic Acetylcholine Receptor Ion Channel at the Binding Site of bis-Ammonium Blockers  Academic Article
• Architectures, mechanisms and molecular evolution of natural product methyltransferases  Academic Article
• Aromatic Residue Position on the Nonpolar Face of Class A Amphipathic Helical Peptides Determines Biological Activity  Academic Article
• Aspartate transcarbamoylase: loss of homotropic but not heterotropic interactions upon modification of the catalytic subunit with a bifunctional reagent  Academic Article
• Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine  Academic Article
• Atomic resolution structure of obelin: soaking with calcium enhances electron density of the second oxygen atom substituted at the C2-position of coelenterazine  Academic Article
• Bax Homodimerization Is Not Required for Bax to Accelerate Chemotherapy-induced Cell Death  Academic Article
• Bcl-2 changes conformation to inhibit Bax oligomerization  Academic Article
• Beta-turns in nascent procollagen are sites of posttranslational enzymatic hydroxylation of proline.  Academic Article
• Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53.  Academic Article
• Binding of solvated peptide (EPLQLKM) with a graphene sheet via simulated coarse-grained approach  Academic Article
• Biologic activity and conformational properties of glucagon and glucagon analogs  Academic Article
• Biologically active calcitonin analogs which have minimal interactions with phospholipids  Academic Article
• Biologically potent analogues of salmon calcitonin which do not contain an N-terminal disulfide-bridged ring structure  Academic Article
• By Increasing the Affinity of Heparin for Fibrin, Zn2+Promotes the Formation of a Ternary Heparin–Thrombin–Fibrin Complex That Protects Thrombin from Inhibition by Antithrombin  Academic Article
• CD,1H NMR and molecular modeling studies of the interaction of Ca2+ with substance P and Ala7-substance P in a non-polar solvent  Academic Article
• Ca2+-dependent Antifreeze Proteins  Academic Article
• Calcium and the Fc Receptor on Human Platelets  Academic Article
• Calcium binding and translocation properties of glucagon and its fragments  Academic Article
• Calorimetric studies of the kinetic unfreezing of molecular motions in hydrated lysozyme, hemoglobin, and myoglobin  Academic Article
• Canadian Association of Neurosciences Review: Polyglutamine Expansion Neurodegenerative Diseases  Academic Article
• Caveolin Scaffolding Region and Cholesterol-rich Domains in Membranes  Academic Article
• Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73  Academic Article
• Characterisation of Neurotrophin Dimers and Monomers  Academic Article
• Characterization of the putative fusogenic domain in vesicular stomatitis virus glycoprotein G.  Academic Article
• Circular dichroism (CD) studies of antagonists derived from parathyroid hormone-related protein  Academic Article
• Circular dichroism studies on lipid-protein complexes of a hydrophobic myelin protein  Academic Article
• Codon bias and frequency-dependent selection on the hemagglutinin epitopes of influenza A virus  Academic Article
• Comparative effects of heparin and LMW heparin on hemostasis  Conference Paper
• Comparative studies of the cross-linked regions of elastin from bovine ligamentum nuchae and bovine, porcine and human aorta  Academic Article
• Comparison of Solution Structures and Stabilities of Native, Partially Unfolded and Partially Refolded Pepsin†  Academic Article
• Conformation of a synthetic hexapeptide substrate of collagen lysyl hydroxylase  Academic Article
• Conformation of cross-linked aspartate transcarbamoylase  Academic Article
• Conformational Changes in Apolipoprotein B Modulate Intracellular Assembly and Degradation of ApoB-Containing Lipoprotein Particles in HepG2 Cells  Academic Article
• Conformational Changes in Thrombin When Complexed by Serpins  Academic Article
• Conformational Correlates of the Epitopes of Human Myelin Basic Protein Peptide 80?89  Academic Article
• Conformational Dimorphism and Transmembrane Orientation of Prion Protein Residues 110−136 in Bicelles†  Academic Article
• Conformational Stability and Membrane Interaction of the Full-Length Ectodomain of HIV-1 gp41: Implication for Mode of Action†  Academic Article
• Conformational Studies on Calcium Binding BytBoc-Leu-Pro-Tyr-Ala-NHCH3, a Tyrosine Kinase Substrate, in a Nonpolar Solvent  Academic Article
• Conformational analysis of d-tubocurarine: Implications for minimal dimensions of its binding site within ion channels  Academic Article
• Conformational and Biological Properties of Partial Sequences of Glucagon  Academic Article
• Conformational and Electrostatic Similarity Between Polyprotonated and Ca2+-Boundμ-Opioid Peptides  Academic Article
• Conformational and biological properties of a covalently linked dimer of glucagon Reaction of mono- and bifunctional sulfenyl halides  Academic Article
• Conformational and biological properties of di[delta-(5-nitro-2-pyrimidyl)ornithine 17,18]glucagon. Role of the arginine residues.  Academic Article
• Conformational and biological properties of glucagon fragments containing residues 1-17 and 19-29  Academic Article
• Conformational and biological properties of partial sequences of salmon calcitonin  Academic Article
• Conformational change and membrane association of the PutA protein are coincident with reduction of its FAD cofactor by proline.  Academic Article
• Conformational determinants in receptor recognition of peptide hormones: interaction of parathyroid hormone with the glucagon receptor  Academic Article
• Conformational flexibility and biological activity of salmon calcitonin  Academic Article
• Conformational flexibility of a myelin protein  Academic Article
• Conformational properties of cyanogen bromide-cleaved glucagon.  Academic Article
• Conformational requirement for lysine hydroxylation in collagen. Structural studies on synthetic peptide substrates of lysyl hydroxylase.  Academic Article
• Conformational studies on analogs of recombinant parathyroid hormone and their interactions with phospholipids.  Academic Article
• Conversion of thrombin into an anticoagulant by protein engineering  Academic Article
• Coordinate Gene Expression of the α3, α4, and α5 Chains of Collagen Type IV  Academic Article
• Coordinated amino acid changes in homologous protein families  Academic Article
• Cracking the allosteric code of NMR chemical shifts  Academic Article
• Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery  Academic Article
• Crystal Structure of a Ca2+-discharged Photoprotein  Academic Article
• Crystal Structure of the Streptomyces coelicolor Sortase E1 Transpeptidase Provides Insight into the Binding Mode of the Novel Class E Sorting Signal  Academic Article
• Crystal Structures of the Streptomyces coelicolor TetR-Like Protein ActR Alone and in Complex with Actinorhodin or the Actinorhodin Biosynthetic Precursor (S)-DNPA  Academic Article
• Crystal structure of a bovine neurophysin II dipeptide complex at 2.8 A determined from the single-wavelength anomalous scattering signal of an incorporated iodine atom.  Academic Article
• Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold  Academic Article
• Crystal structure of an antifreeze polypeptide and its mechanistic implications  Academic Article
• Crystal structure of cGMP-dependent protein kinase Iβ cyclic nucleotide-binding-B domain : Rp-cGMPS complex reveals an apo-like, inactive conformation  Academic Article
• Crystal structure of tert.-butyloxycarbonyl-L-prolyl-D-alanyl-D-alanyl-N-methylamide Dimeric β-sheet formation  Academic Article
• Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases  Academic Article
• Crystallization and preliminary X-ray diffraction studies of glycerol 3-phosphate cytidylyltransferase fromStaphylococcus aureus  Academic Article
• Crystals of modified bovine neurophysin II  Academic Article
• DNA Mismatch Repair: From Structure to Mechanism  Academic Article
• Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIα  Academic Article
• Deletion sequences of salmon calcitonin that retain the essential biological and conformational features of the intact molecule  Academic Article
• Design and function of a conformationally restricted analog of the influenza virus fusion peptide  Academic Article
• Determination of the Topology of the Hydrophobic Segment of Mammalian Diacylglycerol Kinase Epsilon in a Cell Membrane and Its Relationship to Predictions from Modeling  Academic Article
• Dilution Wave and Negative-Order Crystallization Kinetics of Chain Molecules  Academic Article
• Dimerization Is Required for the Activity of the Protein Histidine Kinase CheA That Mediates Signal Transduction in Bacterial Chemotaxis  Academic Article
• Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella  Academic Article
• Disparate Subcellular Localization Patterns of Pseudomonas aeruginosa Type IV Pilus ATPases Involved in Twitching Motility  Academic Article
• Distance-Based Configurational Entropy of Proteins from Molecular Dynamics Simulations  Academic Article
• Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax  Academic Article
• Diversity of antimicrobial peptides and their mechanisms of action  Academic Article
• Docking of Verapamil in a Synthetic Ca2+Channel: Formation of a Ternary Complex Involving Ca2+Ions  Academic Article
• Dopamine receptor modulation by Pro-Leu-Gly-NH2 analogs possessing cyclic amino acid residues at the C-terminal position  Academic Article
• Dopamine receptor modulation by a highly rigid spiro bicyclic peptidomimetic of Pro-Leu-Gly-NH2  Academic Article
• Dopamine receptor modulation by conformationally constrained analogs of Pro-Leu-Gly-NH2  Academic Article
• Dual Function of Mitochondrial Nm23-H4 Protein in Phosphotransfer and Intermembrane Lipid Transfer  Academic Article
• Dynamics of the Fragment of Thrombomodulin Containing the Fourth and Fifth Epidermal Growth Factor-like Domains Correlate with Function†  Academic Article
• Effect of end group blockage on the properties of a class A amphipathic helical peptide  Academic Article
• Effect of microheterogeneity on the structure and function of the myelin basic protein  Academic Article
• Effects of Double-Site Mutations of Vesicular Stomatitis Virus Glycoprotein G on Membrane Fusion Activity  Academic Article
• Effects of Spontaneous Bilayer Curvature on Influenza Virus–mediated Fusion Pores  Academic Article
• Effects of lipid structure on peptide-lipid interactions complexes of salmon calcitonin with phosphatidylglycerol and with phosphatidic acid  Academic Article
• Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event  Academic Article
• Enzyme Evolution Explained (Sort Of)  Academic Article
• Enzymology of lipid A palmitoylation in bacterial outer membranes  Academic Article
• Establishing the Principles of Recognition in the Adenine-Binding Region of an Aminoglycoside Antibiotic Kinase [APH(3‘)-IIIa]†  Academic Article
• Ethanol euthanasia and its effect on the binding of antibody generated against an immunogenic peptide construct  Academic Article
• Evidence for Allosteric Linkage between Exosites 1 and 2 of Thrombin  Academic Article
• Evidence for Calcitonin Receptor Heterogeneity: Binding Studies with Nonhelical Analogs*  Academic Article
• Evidence for the compact conformation of monomeric glucagon. Hydrogen-tritium exchange studies  Academic Article
• Evidence of Kinetic Control of Ligand Binding and Staged Product Release in MurA (Enolpyruvyl UDP-GlcNAc Synthase)-Catalyzed Reactions,  Academic Article
• Evolution of HSP70 gene and its implications regarding relationships between archaebacteria, eubacteria, and eukaryotes  Academic Article
• Examining the Molecular Mechanism of Bcl-2 Family Proteins at Membranes by Fluorescence Spectroscopy  Academic Article
• Exosites 1 and 2 Are Essential for Protection of Fibrin-bound Thrombin from Heparin-catalyzed Inhibition by Antithrombin and Heparin Cofactor II  Academic Article
• Exploring Intermolecular Interactions of a Substrate Binding Protein Using a Riboswitch-Based Sensor  Academic Article
• Expression, purification, crystallization and preliminary X-ray analysis ofPseudomonas fluorescensAlgK  Academic Article
• Factors Determining Vesicular Lipid Mixing Induced by Shortened Constructs of Influenza Hemagglutinin  Academic Article
• Fluorescence Activation Imaging of Cytochrome c Released from Mitochondria Using Aptameric Nanosensor  Academic Article
• Fluorescence Resonance Energy Transfer in Gaseous, Mass-Selected Polyproline Peptides  Academic Article
• Formation of dissociated enzyme subunits by chemical treatment during renaturation  Academic Article
• Formation of water-soluble complex between the 1-34 fragment of parathyroid hormone and dimyristoylphosphatidylcholine  Academic Article
• From The Cover: The integral membrane enzyme PagP alternates between two dynamically distinct states  Academic Article
• Functional metagenomics reveals novel β-galactosidases not predictable from gene sequences  Academic Article
• Fusion peptides and the mechanism of viral fusion  Academic Article
• GCN4 enhances the stability of the pore domain of potassium channel KcsA  Academic Article
• Gene Gain and Gene Loss in Streptococcus: Is It Driven by Habitat?  Academic Article
• Genome duplication events have led to a diversification in the CPT I gene family in fish  Academic Article
• Gi Activator Region of α2A-Adrenergic Receptors: Distinct Basic Residues Mediate Gi versus Gs Activation  Academic Article
• Glucose-Induced Thermal Stabilization of the Native Conformation of GLUT 1  Academic Article
• Helix Induction in Antimicrobial Peptides by Alginate in Biofilms  Academic Article
• Heparin Dependent Coiled‐Coil Formation  Academic Article
• Hierarchical, self-similar structure in native squid pen  Academic Article
• High-quality 3D structures shine light on antibacterial, anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments  Academic Article
• High-throughput screening of holoprotein conformational stability by dynamic ligand exchange-affinity capillary electrophoresis  Academic Article
• Homology Model of Dihydropyridine Receptor: Implications for L-type Ca2+ Channel Modulation by Agonists and Antagonists  Academic Article
• Homology modeling of Kv1.5 channel block by cationic and electroneutral ligands  Academic Article
• How Batrachotoxin Modifies the Sodium Channel Permeation Pathway: Computer Modeling and Site-Directed Mutagenesis  Academic Article
• Huntingtin’s spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function  Academic Article
• Hybrid aspartate transcarbamoylase containing cross-linked subunits  Academic Article
• Hydration dynamics of the collagen triple helix by NMR11Edited by P. E. Wright  Academic Article
• Identification and Structure Characterization of a Cdk Inhibitory Peptide Derived from Neuronal-specific Cdk5 Activator  Academic Article
• Identification of Critical Residues on Thrombin Mediating Its Interaction with Fibrin  Academic Article
• Identification of Pharmacological Chaperones for Gaucher Disease and Characterization of Their Effects on β-Glucocerebrosidase by Hydrogen/Deuterium Exchange Mass Spectrometry  Academic Article
• Identification of SVTCG in thrombospondin as the conformation-dependent, high affinity binding site for its receptor, CD36.  Academic Article
• Identification of a diphtheria toxin‐like gene family beyond the Corynebacterium genus  Academic Article
• Identification of hydrophobic residues in the signal sequence of mitochondrial preornithine carbamyltransferase that enhance the rate of precursor import.  Academic Article
• Identification of the Factor VIIa Binding Site on Tissue Factor by Homologous Loop Swap and Alanine Scanning Mutagenesis  Academic Article
• Identification, Structure, and Function of a Novel Type VI Secretion Peptidoglycan Glycoside Hydrolase Effector-Immunity Pair  Academic Article
• Import of precursor proteins into mitochondria: site of polypeptide unfolding.  Academic Article
• In Silico Activation of KcsA K+ Channel by Lateral Forces Applied to the C-Termini of Inner Helices  Academic Article
• Influence of nanoparticle size on the pH-dependent structure of adsorbed proteins studied with quantitative localized surface plasmon spectroscopy  Academic Article
• Infrared spectroscopic evidence of conformational transitions of an atrial natriuretic peptide.  Academic Article
• Inhibition of Aminoglycoside Antibiotic Resistance Enzymes by Protein Kinase Inhibitors  Academic Article
• Inscribing the Perimeter of the PagP Hydrocarbon Ruler by Site-Specific Chemical Alkylation  Academic Article
• Interaction of NDPK-D with cardiolipin-containing membranes: Structural basis and implications for mitochondrial physiology  Academic Article
• Interaction of Peptide Substrates of Fibroblast Collagenase with Divalent Cations: Ca2+ Binding by Substrate as a Suggested Recognition Signal for Collagenase Action  Academic Article
• Interaction of atriopeptin III with lipids and detergents  Academic Article
• Interaction of glucagon with dimyristoyl glycerophosphocholine  Academic Article
• Interaction of oxytocin with Ca2+: I. CD and fluorescence spectral characterization and comparison with vasopressin.  Academic Article
• Interaction of oxytocin with Ca2+: II. Proton magnetic resonance and molecular modeling studies of conformations of the hormone and its Ca2+ complex.  Academic Article
• Interaction of prolyl 4-hydroxylase with synthetic peptide substrates. A conformational model for collagen proline hydroxylation.  Academic Article
• Interaction of substance P and its N- and C-terminal fragments with Ca2+: Implications for hormone action  Academic Article
• Interaction with a Membrane Surface Triggers a Reversible Conformational Change in Bax Normally Associated with Induction of Apoptosis  Academic Article
• Interactions of plasminogen and fibrinogen with model silica glass surfaces: Adsorption from plasma and enzymatic activity studies  Academic Article
• Intersegment Hydrogen Bonds as Possible Structural Determinants of the N/Q/R Site in Glutamate Receptors  Academic Article
• Intracellular targeting, interaction with Src homology 3 (SH3) domains and rolipram-detected conformational switches in cAMP-specific PDE4A phosphodiesterase  Academic Article
• Intrinsic fluorescence of a hydrophobic myelin protein and some complexes with phospholipids  Academic Article
• Irreversible Block of Cardiac Mutant Na+Channels by Batrachotoxin  Academic Article
• Isolation and characterization of insertion mutants in E1A of adenovirus type 5  Academic Article
• Isolation and characterization of the eighth component of the bovine complement system.  Academic Article
• Juxtamembrane Protein Segments that Contribute to Recruitment of Cholesterol into Domains†  Academic Article
• KvAP-Based Model of the Pore Region of Shaker Potassium Channel Is Consistent with Cadmium- and Ligand-Binding Experiments  Academic Article
• L-Phenylalanine induced changes of sulfhydryl reactivity in rabbit muscle pyruvate kinase  Academic Article
• Label-Free Assay for Thermodynamic Analysis of Protein−Ligand Interactions: A Multivariate Strategy for Allosteric Ligand Screening†  Academic Article
• Lifeact cannot visualize some forms of stress-induced twisted f-actin  Academic Article
• Lineage-specific mutational clustering in protein structures predicts evolutionary shifts in function  Academic Article
• Lipid binding protein response to a bile acid library: a combined NMR and statistical approach  Academic Article
• Lipopeptaibols, a novel family of membrane active, antimicrobial peptides  Academic Article
• Lipophosphoglycan of Leishmania donovani inhibits lipid vesicle fusion induced by the N-terminal extremity of viral fusogenic Simian immunodeficiency virus protein  Academic Article
• Lipoprotein Complexes between Glucagon and Dimyristoylglycerophosphocholine (Dimyristoyl Phosphatidylcholine)  Conference Paper
• Local pH-dependent conformational changes leading to proteolytic susceptibility of cystatin C  Academic Article
• Localization of the Thrombin-binding Domain on Prothrombin Fragment 2  Academic Article
• Low-energy conformations of two lysine-containing tetrapeptides of collagen: Implications for posttranslational lysine hydroxylation  Academic Article
• Mammalian diacylglycerol kinases: Molecular interactions and biological functions of selected isoforms  Academic Article
• Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα  Academic Article
• Measuring Dynamics in Weakly Structured Regions of Proteins Using Microfluidics-Enabled Subsecond H/D Exchange Mass Spectrometry  Academic Article
• Mechanism of Catalysis of Inhibition of Factor IXa by Antithrombin in the Presence of Heparin or Pentasaccharide  Academic Article
• Mechanism of action of the novel plasma membrane Ca2+-pump inhibitor caloxin  Academic Article
• Mechanisms by Which Soluble Endothelial Cell Protein C Receptor Modulates Protein C and Activated Protein C Function  Academic Article
• Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides  Academic Article
• Mechanisms of Action of Bcl-2 Family Proteins  Academic Article
• Membrane Cholesterol Reduces Polymyxin B Nephrotoxicity in Renal Membrane Analogs  Academic Article
• Membrane Interactions of Mutated Forms of the Influenza Fusion Peptide†  Academic Article
• Metal-Chelate Immobilization of Lipase onto Polyethylenimine Coated MCM-41 for Apple Flavor Synthesis  Academic Article
• Microtubules, mitochondria, and molecular chaperones: a new hypothesis for in vivo assembly of microtubules  Academic Article
• Mimicking the membrane-mediated conformation of dynorphin A-(1-13)-peptide: circular dichroism and nuclear magnetic resonance studies in methanolic solution  Academic Article
• Mitochondrial import of the human chaperonin (HSP60) protein  Academic Article
• Mitochondrial precursor protein. Effects of 70-kilodalton heat shock protein on polypeptide folding, aggregation, and import competence.  Academic Article
• Modeling P-Loops Domain of Sodium Channel: Homology with Potassium Channels and Interaction with Ligands  Academic Article
• Modular Evolution and the Origins of Symmetry: Reconstruction of a Three-Fold Symmetric Globular Protein  Academic Article
• Molecular Evolution of Cytochrome c Oxidase Underlies High-Altitude Adaptation in the Bar-Headed Goose  Academic Article
• Molecular Mechanism for Lateral Lipid Diffusion between the Outer Membrane External Leaflet and a β-Barrel Hydrocarbon Ruler  Academic Article
• Molecular Modeling of Benzothiazepine Binding in the L-type Calcium Channel  Academic Article
• Molecular cloning of a cDNA encoding the nerve growth factor precursor from Mastomys natalensis  Academic Article
• Molecular interactions in the model lipoprotein complex formed between glucagon and dimyristoylglycerophosphocholine  Academic Article
• Molecular properties of diacylglycerol kinase-epsilon in relation to function  Academic Article
• Molecular structural analysis of a novel and de-novo mutation in theSERPINC1gene associated with type 1 antithrombin deficiency  Academic Article
• Monte Carlo-minimized energy profile of estradiol in the ligand-binding tunnel of 17?-hydroxysteroid dehydrogenase: Atomic mechanisms of steroid recognition  Academic Article
• Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin generation  Academic Article
• Multiple conformations facilitate PilT function in the type IV pilus  Academic Article
• Mutational analysis of the vesicular stomatitis virus glycoprotein G for membrane fusion domains.  Academic Article
• Mutations inSYNGAP1Cause Intellectual Disability, Autism, and a Specific Form of Epilepsy by Inducing Haploinsufficiency  Academic Article
• Myristoylation, a Protruding Loop, and Structural Plasticity Are Essential Features of a Nonenveloped Virus Fusion Peptide Motif  Academic Article
• NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit  Academic Article
• Nature of the cysteinyl residues in lipophilin from human myelin.  Academic Article
• NleG Type 3 Effectors from Enterohaemorrhagic Escherichia coli Are U-Box E3 Ubiquitin Ligases  Academic Article
• Novel Role for PilNO in Type IV Pilus Retraction Revealed by Alignment Subcomplex Mutations  Academic Article
• On the Interaction Between gp41 and Membranes: The Immunodominant Loop Stabilizes gp41 Helical Hairpin Conformation  Academic Article
• On the physicochemical and chemical properties of α1-acid glycoproteins from mammalian and avian plasmas  Academic Article
• Ordered surface carbons distinguish antifreeze proteins and their ice-binding regions  Academic Article
• PagP Crystallized from SDS/Cosolvent Reveals the Route for Phospholipid Access to the Hydrocarbon Ruler  Academic Article
• PelA and PelB proteins form a modification and secretion complex essential for Pel polysaccharide-dependent biofilm formation inPseudomonas aeruginosa  Academic Article
• Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin  Academic Article
• Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function  Academic Article
• Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin  Academic Article
• Polypeptide models of collagen. Solution properties of (Gly-Pro-Sar)n and (Gly-Sar-Pro)n  Academic Article
• Polyphosphate binds with high affinity to exosite II of thrombin  Academic Article
• Potassium, sodium, calcium and glutamate-gated channels: pore architecture and ligand action  Academic Article
• Predicting novel disease mutations in the cardiac sodium channel  Academic Article
• Predominant Interactions between μ-Conotoxin Arg-13 and the Skeletal Muscle Na+Channel Localized by Mutant Cycle Analysis†  Academic Article
• Preparation and X-ray crystallographic analysis of recombinant obelin crystals diffracting to beyond 1.1 Å  Academic Article
• Proline-containing beta-turns. IV. Crystal and solution conformations of tert.-butyloxycarbonyl-L-prolyl-D-alanine and tert.-butyloxycarbonyl-L-prolyl-D-alanyl-L-alanine.  Academic Article
• Proline-containing β-turns in peptides and proteins: Analysis of structural data on globular proteins  Academic Article
• Properties of lipid complexes with amphipathic helix-forming peptides. Role of distribution of peptide charges.  Academic Article
• Protein Engineering Thrombin for Optimal Specificity and Potency of Anticoagulant Activityin Vivo  Academic Article
• Protein-Induced Formation of Cholesterol-Rich Domains†  Academic Article
• Purification and characterization of the carboxyl-terminal transactivation domain of Vmw65 from herpes simplex virus type 1.  Academic Article
• Purification of chick oviduct progesterone receptor apoprotein  Academic Article
• Quantification of protein surfaces, volumes and atom-atom contacts using a constrained Voronoi procedure  Academic Article
• Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth  Academic Article
• Recent Developments in the Molecular Biology of Extremely Halophilic Bacteria  Academic Article
• Reciprocal effects of apolipoprotein and lytic peptide analogs on membranes. Cross-sectional molecular shapes of amphipathic alpha helixes control membrane stability.  Academic Article
• Regulating cell death at, on, and in membranes  Academic Article
• Regulation of HCN Ion Channels by Non-canonical Cyclic Nucleotides  Academic Article
• Regulation of apolipoprotein B biogenesis in human hepatocytes: Posttranscriptional control mechanisms that determine the hepatic production of apolipoprotein B-containing lipoproteins  Conference Paper
• Regulators of oxidative stress response genes in Escherichia coli and their functional conservation in bacteria  Academic Article
• Relationship of membrane sidedness to the effects of the lipophosphoglycan of Leishmania donovani on the fusion of influenza virus  Academic Article
• Relationships among several different non-homologous polypeptide hormones  Academic Article
• Resistance of lipophilin, a hydrophobic myelin protein, to denaturation by urea and guanidinium salts.  Academic Article
• Reversible unfolding of glucagon by urea and temperature changes  Academic Article
• Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC)  Academic Article
• Role of Dynamics in the Autoinhibition and Activation of the Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) Ion Channels  Academic Article
• Role of calcium in stabilizing the structure of hyalin, a major protein component of the sea urchin extraembryonic hyaline layer  Academic Article
• Role of prenylation in the interaction of the a-factor mating pheromone with phospholipid bilayers  Academic Article
• Role of the Glu Residues of the Influenza Hemagglutinin Fusion Peptide in the pH Dependence of Fusion Activity  Academic Article
• Roles of Low Specificity and Cofactor Interaction Sites on Thrombin during Factor XIII Activation  Academic Article
• Roles of Salt and Conformation in the Biological and Physicochemical Behavior of Protegrin-1 and Designed Analogues:  Correlation of Antimicrobial, Hemolytic, and Lipid Bilayer-Perturbing Activities†  Academic Article
• Rotatory characteristics of the β-structure in non-aqueous solution  Academic Article
• Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action  Academic Article
• Secondary structure of charge isomers of myelin basic protein before and after phosphorylation  Academic Article
• Self-assembly of influenza hemagglutinin: studies of ectodomain aggregation by in situ atomic force microscopy  Academic Article
• Side chain flexibility and the pore dimensions in the GABAA receptor  Academic Article
• Single-Residue Changes in the C-Terminal Disulfide-Bonded Loop of the Pseudomonas aeruginosa Type IV Pilin Influence Pilus Assembly and Twitching Motility  Academic Article
• Size-dependent denaturing kinetics of bovine serum albumin adsorbed onto gold nanospheres  Academic Article
• Sodium Channels: Ionic Model of Slow Inactivation and State-Dependent Drug Binding  Academic Article
• Solution Studies of Isepamicin and Conformational Comparisons between Isepamicin and Butirosin A When Bound to an Aminoglycoside 6‘-N-Acetyltransferase Determined by NMR Spectroscopy  Academic Article
• Solution structure and dynamics of the outer membrane enzyme PagP by NMR  Academic Article
• Some experimental approaches for studying subunit interactions in enzymes  Academic Article
• Spatial structure of the novel light-sensitive photoprotein berovin from the ctenophore Beroe abyssicola in the Ca2+-loaded apoprotein conformation state  Academic Article
• Species Specificity of Ectromelia Virus and Vaccinia Virus Interferon-γ Binding Proteins  Academic Article
• Stabilization of the relaxed state of aspartate transcarbamoylase by modification with a bifunctional reagent.  Academic Article
• Strategies for development of novel antithrombotics: modulating thrombin's procoagulant and anticoagulant properties  Academic Article
• Structural Aspects of Ca2+Binding by Acyclic Peptides: Low-Energy Conformational Domains and Molecular Dynamics of N-acetyl-L-prolyl-D-alanyl-L-alanine-N'-methylamide  Academic Article
• Structural Aspects of Hydroxyproline-Containing Proteins  Academic Article
• Structural Characterization of Novel Pseudomonas aeruginosa Type IV Pilins  Academic Article
• Structural Effects of a Covalent Linkage Between Antithrombin and Heparin: Covalent N-Terminus Attachment of Heparin Enhances the Maintenance of Antithrombin's Activated State  Academic Article
• Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations  Academic Article
• Structural Model for Dihydropyridine Binding to L-type Calcium Channels  Academic Article
• Structural analysis and amphiphilic properties of a chemically synthesized mitochondrial signal peptide.  Academic Article
• Structural and Functional Plasticity of Antibiotic Resistance Nucleotidylyltransferases Revealed by Molecular Characterization of Lincosamide Nucleotidylyltransferases Lnu(A) and Lnu(D)  Academic Article
• Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins  Academic Article
• Structural basis for the emission of violet bioluminescence from a W92F obelin mutant  Academic Article
• Structural biology of membrane-intrinsic β-barrel enzymes: Sentinels of the bacterial outer membrane  Academic Article
• Structural model of a synthetic Ca2+ channel with bound Ca2+ ions and dihydropyridine ligand  Academic Article
• Structural motif screening reveals a novel, conserved carbohydrate-binding surface in the pathogenesis-related protein PR-5d  Academic Article
• Structural requirements for the activation of human factor VIII by thrombin  Academic Article
• Structural studies on cross-linked regions of elastin.  Academic Article
• Structural studies on the freezing-point-depressing protein of the winter flounder Pseudopleuronectes americanus  Academic Article
• Structurally simplified biphenyl combretastatin A4 derivatives retain in vitro anti-cancer activity dependent on mitotic arrest  Academic Article
• Structural–Functional Studies ofBurkholderia cenocepaciad-Glycero-β-d-manno-heptose 7-Phosphate Kinase (HldA) and Characterization of Inhibitors with Antibiotic Adjuvant and Antivirulence Properties  Academic Article
• Structure and Activity of the Metal-independent Fructose-1,6-bisphosphatase YK23 fromSaccharomyces cerevisiae  Academic Article
• Structure and Functional Relationships in Human pur H  Academic Article
• Structure and function of aspartate transcarbamoylase studied using chymotrypsin as a probe  Academic Article
• Structure and mechanism ofStaphylococcus aureusTarM, the wall teichoic acid α-glycosyltransferase  Academic Article
• Structure of the Pseudomonas aeruginosa Type IVa Pilus Secretin at 7.4 Å  Academic Article
• Structure of the bacterial teichoic acid polymerase TagF provides insights into membrane association and catalysis  Academic Article
• Structure of the carboxy-terminal PH domain of pleckstrin at 2.1 Å  Academic Article
• Structure of transfection-active histone H1/DNA complexes.  Academic Article
• Structure-Activity Studies on Mammalian Adenosine Kinase  Academic Article
• Structure-function relationship in a winter flounder antifreeze polypeptide. II. Alteration of the component growth rates of ice by synthetic antifreeze polypeptides.  Academic Article
• Structure-function relationships in a winter flounder antifreeze polypeptide. I. Stabilization of an alpha-helical antifreeze polypeptide by charged-group and hydrophobic interactions.  Academic Article
• Structures of shorthorn sculpin antifreeze polypeptides  Academic Article
• Structure–function studies on Hsp47: pH-dependent inhibition of collagen fibril formation in vitro  Academic Article
• Studies of synthetic peptide analogs of the amphipathic helix. Effect of charge distribution, hydrophobicity, and secondary structure on lipid association and lecithin:cholesterol acyltransferase activation.  Academic Article
• Studies on nucleotidases in plants: Fluorescence and kinetic properties of nucleotide pyrophosphatase from mung bean (Phaseolus aureus) seedlings  Academic Article
• Studies on protein subunits  Academic Article
• Studies on protein subunits. 3. Kinetic evidence for the presence of active subunits during the renaturation of muscle aldolase.  Academic Article
• Studies on the Alkaline Denaturation of Glucagon  Academic Article
• Study of a series of analogs of salmon calcitonin in which alanine replaces leucine  Academic Article
• Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis  Academic Article
• Substrate-Induced Translocation of PKC-α to the Membrane  Academic Article
• Subunit interactions in aspartate transcarbamylase. A model for the allosteric mechanism.  Academic Article
• Subunit interactions in aspartate transcarbamylase. Characterization of a complex between the catalytic and the regulatory subunits.  Academic Article
• Subunit interactions in aspartate transcarbamylase. The interaction between catalytic and regulatory subunits and the effect of ligands.  Academic Article
• Sulfonation of glycopeptide antibiotics by sulfotransferase StaL depends on conformational flexibility of aglycone scaffold  Academic Article
• Synthesis and Processing of the Haemagglutinin--esterase Glycoprotein of Bovine Coronavirus Encoded in the E3 Region of Adenovirus  Academic Article
• Synthesis and dopamine receptor modulating activity of unsubstituted and substituted triproline analogues of l-prolyl-l-leucyl-glycinamide (PLG)  Academic Article
• Synthesis of Pro-Leu-Gly-NH2 analogs modified at the prolyl residue and evaluation of their effects on the receptor binding activity of the central dopamine receptor agonist, ADTN  Academic Article
• Synthetic beta-turn peptides as substrates for a tyrosine protein kinase.  Academic Article
• The Conserved Tetratricopeptide Repeat-Containing C-Terminal Domain of Pseudomonas aeruginosa FimV Is Required for Its Cyclic AMP-Dependent and -Independent Functions  Academic Article
• The Folded Conformation of the Encephalitogenic Protein of the Human Brain  Academic Article
• The Mechanism of Protein Crystal Growth from Lipid Layers  Academic Article
• The Platform Protein Is Essential for Type IV Pilus Biogenesis  Academic Article
• The Solution Conformational Features of Two Highly Homologous Antigenic Peptides of Foot-and-mouth Disease Virus Serotype A, Variants A and USA, Correlate with their Serological Properties  Academic Article
• The Solution Structure and Dynamics of an Arc Repressor Mutant Reveal Premelting Conformational Changes Related to DNA Binding†  Academic Article
• The Structural Integrity of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII  Academic Article
• The Structures of Some Peptides from Bee Venom  Academic Article
• The bacterial Kdp K + -ATPase and its relation to other transport ATPases, such as the Na + /K + - and Ca 2+ -ATPases in higher organisms  Academic Article
• The biological potency of a series of analogues of human calcitonin correlates with their interactions with phospholipids  Academic Article
• The blood compatibility challenge. Part 2: Protein adsorption phenomena governing blood reactivity  Academic Article
• The ectodomain of HA2 of influenza virus promotes rapid ph dependent membrane fusion 1 1Edited by A. R. Fersht  Academic Article
• The effects of the trinitrophenylation of the amino groups of glucagon on its conformational properties and on its ability to activate rat liver adenylyl cyclase  Academic Article
• The entericidin locus of Escherichia coli and its implications for programmed bacterial cell death  Academic Article
• The hydrophobic moment of the amphipathic helix of salmon calcitonin and biological potency  Academic Article
• The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase  Academic Article
• The molecular basis of the expansive substrate specificity of the antibiotic resistance enzyme aminoglycoside acetyltransferase-6'-aminoglycoside phosphotransferase-2". The role of ASP-99 as an active site base important for acetyl transfer  Academic Article
• The ordered structure of the encephalitogenic protein from normal human myelin  Academic Article
• The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults  Academic Article
• The role of hydroxyproline in collagen folding: Conformational energy calculations on oligopeptides containing proline and hydroxyproline  Academic Article
• The role of molybdenum in the synthesis of Neurospora nitrate reductase  Academic Article
• The role of nonspecific hydrophobic interactions in the biological activity of N epsilon-acyl derivatives of glucagon. Studies of conformation, receptor binding, and adenylate cyclase activation.  Academic Article
• The secondary structure of a membrane-embedded peptide from the carboxy terminus of lipophilin as revealed by circular dichorism  Academic Article
• The solution structure of Lac repressor headpiece 62 complexed to a symmetrical lac operator  Academic Article
• The structural basis of molecular adaptation  Academic Article
• The structure of DdrB from Deinococcus: a new fold for single-stranded DNA binding proteins  Academic Article
• Theoretical study of interaction of winter flounder antifreeze protein with ice  Academic Article
• Therapeutic Peptides: New Arsenal Against Drug Resistant Pathogens  Academic Article
• Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase  Academic Article
• Towards a structure-function analysis of bovine lactoferricin and related tryptophan- and arginine-containing peptides  Conference Paper
• Transformation of MutL by ATP Binding and Hydrolysis  Academic Article
• Transmembrane helix prediction using amino acid property features and latent semantic analysis  Academic Article
• Two Homologous Apolipoprotein AI Mimetic Peptides  Academic Article
• Ultrasonic and Densimetric Characterization of the Association of Cyclic AMP with the cAMP-Binding Domain of the Exchange Protein EPAC1  Academic Article
• Using FLIM-FRET to Measure Conformational Changes of Transglutaminase Type 2 in Live Cells  Academic Article
• Vacuum ultraviolet circular dichroism spectrum of β-turn in solution  Academic Article
• Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface  Academic Article
• Volume properties of mixtures of lipophilin and dimyristoylphosphatidylcholine  Academic Article
• YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit  Academic Article
• [51] Chemical stabilization of conformational states of aspartate transcarbamoylase  Academic Article
• [Boundaries of the butyrylcholinesterase anion site from data of a conformational analysis of substrates].  Academic Article
• [Determination of productive conformations of acetylcholinesterase substrates using theoretical conformational analysis].  Academic Article
• [MOLECULAR EVOLUTION OF ION CHANNELS: AMINO ACID SEQUENCES AND 3D STRUCTURES].  Academic Article
• [Productive conformations of ligands and topography of the alpha1-adrenoreceptor active site based on theoretical conformation analysis].  Academic Article
• [Structure of collagen with a new net of hydrogen bonds].  Academic Article
• [The conformational aspects of the interaction of the cholinesterases of Pacific Ocean squid and vertebrates with derivatives of polymethylene bis(trimethylammonium)].  Academic Article
• hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization  Academic Article
• l-Hydroxyproline and d-Proline Catabolism in Sinorhizobium meliloti  Academic Article
• tBid Undergoes Multiple Conformational Changes at the Membrane Required for Bax Activation  Academic Article
• β-Bend conformation of CH3CO-Pro-Pro-Gly-Pro-NHCH3: Implications for posttranslational proline hydroxylation in collagen  Academic Article
• β-STRUCTURE OF POLYPEPTIDES IN NON-AQUEOUS SOLUTIONS: I. Spectral Characteristics of the Polypeptide Backbone  Academic Article
• β-STRUCTURE OF POLYPEPTIDES IN NON-AQUEOUS SOLUTIONS: II. Side-Chain Orientation  Academic Article