Journal article
Enzymology of lipid A palmitoylation in bacterial outer membranes.
Abstract
The enzymology of palmitate addition to lipid A can be traced to the early discovery of monosaccharide lipid A precursors, but the functional importance of lipid A palmitoylation in bacterial resistance to the host immune response has emerged only recently. Lipid A palmitoylation in enterobacteria is determined by a PhoP/PhoQ-activated gene pagP, which encodes an unusual outer membrane enzyme of lipid A biosynthesis. PagP structure and dynamics …
Authors
Bishop RE; Lo EI; Khan MA; El Zoeiby A; Jia W
Journal
Innate Immunity, Vol. 10, No. 2, pp. 107–112
Publisher
SAGE Publications
Publication Date
2004
DOI
10.1179/096805104225004004
ISSN
1753-4259