Polypeptide models of collagen. Solution properties of (Gly‐Pro‐Sar)n and (Gly‐Sar‐Pro)n Journal Articles uri icon

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abstract

  • AbstractOur studies on the solution conformation of (Gly‐Pro‐Sar)n and (Gly‐Sar‐Pro)n synthesized as polypeptide models for collagen are reported. It is found that, while (Gly‐Pro‐Sar)n exists in ordered triple‐helical conformation, (Gly‐Sar‐Pro)n remains as a disordered random coil in water. Addition of certain helix‐promoting solvents seems to generate order in (Gly‐Sar‐Pro)n.

publication date

  • April 1976