Journal article
[MOLECULAR EVOLUTION OF ION CHANNELS: AMINO ACID SEQUENCES AND 3D STRUCTURES].
Abstract
An integral part of modern evolutionary biology is comparative analysis of structure and function of macromolecules such as proteins. The first and critical step to understand evolution of homologous proteins is their amino acid sequence alignment. However, standard algorithms fop not provide unambiguous sequence alignments for proteins of poor homology. More reliable results can be obtained by comparing experimental 3D structures obtained at …
Authors
Korkosh VS; Zhorov BS; Tikhonov DB
Journal
Zhurnal Evoliutsionnoi Biokhimii I Fiziologii, Vol. 52, No. 1, pp. 26–33
Publication Date
2016
ISSN
0044-4529