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Coordinated amino acid changes in homologous...
Journal article

Coordinated amino acid changes in homologous protein families*

Abstract

In the tobamovirus coat protein family, amino acid residues at some spatially close positions are found to be substituted in a coordinated manner [Altschuh et al. (1987) J. Mol. Biol., 193, 693]. Therefore, these positions show an identical pattern of amino acid substitutions when amino acid sequences of these homologous proteins are aligned. Based on this principle, coordinated substitutions have been searched for in three additional protein …

Authors

Altschuh D; Vernet T; Berti P; Moras D; Nagai K

Journal

Protein Engineering Design and Selection, Vol. 2, No. 3, pp. 193–199

Publisher

Oxford University Press (OUP)

Publication Date

1988

DOI

10.1093/protein/2.3.193

ISSN

1741-0126