Journal article
The Mechanism of Protein Crystal Growth from Lipid Layers
Abstract
Two-dimensional (2D) crystals of proteins on lipid monolayers can initiate the formation of large three-dimensional (3D) crystals suitable for X-ray diffraction studies. The role of the 2D crystals in this process has not been firmly established. While it is likely that the 2D crystals serve as nuclei for epitaxial crystal growth, other mechanisms, such as non-specific nucleation induced by the high local concentration of the protein at the …
Authors
Hemming SA; Bochkarev A; Darst SA; Kornberg RD; Ala P; Yang DSC; Edwards AM
Journal
Journal of Molecular Biology, Vol. 246, No. 2, pp. 308–316
Publisher
Elsevier
Publication Date
February 1995
DOI
10.1006/jmbi.1994.0086
ISSN
0022-2836