Nuclear Proteins Concept

subject area of

• A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer  Journal Articles
• A Novel Double-stranded RNA-binding Protein, Disco Interacting Protein 1 (DIP1), Contributes to Cell Fate Decisions during Drosophila Development  Journal Articles
• A Role of p73 in Mitotic Exit  Journal Articles
• A candidate transacting modulator of fetal hemoglobin gene expression in the Arab—Indian haplotype of sickle cell anemia  Journal Articles
• A mitochondrial ketogenic enzyme regulates its gene expression by association with the nuclear hormone receptor PPARα  Journal Articles
• A novel GFP reporter mouse reveals Mustn1 expression in adult regenerating skeletal muscle, activated satellite cells and differentiating myoblasts  Journal Articles
• A patient-derived cellular model for Huntington’s disease reveals phenotypes at clinically relevant CAG lengths  Journal Articles
• A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy  Journal Articles
• ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence  Journal Articles
• Absence of p21CIP Rescues Myogenic Progenitor Cell Proliferative and Regenerative Capacity in Foxk1 Null Mice  Journal Articles
• Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor α are altered by the centrosome-associated protein CAP350  Journal Articles
• All colonies of CHO-K1 cells surviving γ-irradiation contain non-viable cells  Journal Articles
• An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein  Journal Articles
• Analysis of human MDM4 variants in papillary thyroid carcinomas reveals new potential markers of cancer properties  Journal Articles
• Analysis of p73 expression pattern in acute myeloid leukemias: lack of ΔN-p73 expression is a frequent feature of acute promyelocytic leukemia  Journal Articles
• Antagonistic Bacterial Interactions Help Shape Host-Symbiont Dynamics within the Fungus-Growing Ant-Microbe Mutualism  Journal Articles
• Antagonistic effects of the SRp30c protein and cryptic 5' splice sites on the alternative splicing of the apoptotic regulator Bcl-x.  Journal Articles
• BAFopathies’ DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin–Siris and Nicolaides–Baraitser syndromes  Journal Articles
• BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia  Journal Articles
• BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies  Journal Articles
• BCL11A represses HBG transcription in K562 cells  Journal Articles
• BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation  Journal Articles
• BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage  Journal Articles
• Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells  Journal Articles
• Bmi1 promotes prostate tumorigenesis via inhibiting p16INK4A and p14ARF expression  Journal Articles
• Bortezomib protects from varicose‐like venous remodeling  Journal Articles
• CDC42 regulates the expression of superficial zone molecules in part through the actin cytoskeleton and myocardin‐related transcription factor‐A  Journal Articles
• Canadian Association of Neurosciences Review: Polyglutamine Expansion Neurodegenerative Diseases  Journal Articles
• Case report of a pan‐cytokeratin negative NUT midline carcinoma of pulmonary origin, a BRD3‐NUT variant: Challenges in cytomorphologic presentation  Journal Articles
• Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres  Journal Articles
• Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins.  Journal Articles
• Cellular and Molecular Regulation of Skeletal Muscle Side Population Cells  Journal Articles
• Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73  Journal Articles
• Characterization of SERCA2b Ca2+–Mg2+ ATPase mRNA decay by nuclear proteins  Journal Articles
• Characterization of the mouse lysosomal sialidase promoter  Journal Articles
• Che-1 Promotes Tumor Cell Survival by Sustaining Mutant p53 Transcription and Inhibiting DNA Damage Response Activation  Journal Articles
• Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma  Journal Articles
• Chromosome content and ultrastructure of radiation-induced micronuclei  Journal Articles
• Clinical features of facioscapulohumeral muscular dystrophy 2  Journal Articles
• Cloning of a Chinese hamster protein homologous to the mouse t-complex protein TCP-1: Structural similarity to the ubiquitous ‘chaperonin’ family of heat-shock proteins  Journal Articles
• Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas  Journal Articles
• Compromised genomic integrity impedes muscle growth after Atrx inactivation  Journal Articles
• Control of Centromere Localization of the MEI-S332 Cohesion Protection Protein  Journal Articles
• Control of SERCA2a Ca2+ pump mRNA stability by nuclear proteins: role of domains in the 3′-untranslated region  Journal Articles
• Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers  Journal Articles
• CtIP/Ctp1/Sae2, molecular form fit for function  Journal Articles
• Culture of human esophageal endoscopic biopsies  Journal Articles
• Cytogenetic Prognostication Within Medulloblastoma Subgroups  Journal Articles
• Cytosolic localization of Fox proteins in motor neurons of G93A SOD1 mice  Journal Articles
• DNA Damage-Dependent Acetylation of p73 Dictates the Selective Activation of Apoptotic Target Genes  Journal Articles
• DNp73α protects myogenic cells from apoptosis  Journal Articles
• Definition of a Consensus Transportin-specific Nucleocytoplasmic Transport Signal  Journal Articles
• Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes  Journal Articles
• Detection of an Involvement of the Human Mismatch Repair Genes hMLH1 and hMSH2 in Nucleotide Excision Repair Is Dependent on UVC Fluence to Cells  Journal Articles
• Determination of the Functional Domain Organization of the Importin α Nuclear Import Factor  Journal Articles
• Distribution of snRNPs, splicing factor SC-35 and actin in interphase nuclei: immunocytochemical evidence for differential distribution during changes in functional states  Journal Articles
• Drosophila ELYS regulates Dorsal dynamics during development  Journal Articles
• EMSY and CCND1 amplification in familial breast cancer: from the Ontario site of the Breast Cancer Family Registry  Journal Articles
• Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches  Journal Articles
• Endometriosis-Associated Ovarian Carcinomas  Journal Articles
• Enhanced cell‐free transcription of the ribosomal protein L₃₂ gene by the polyoma virus enhancer PEA3 DNA‐binding protein  Journal Articles
• Evidence for Tissue-Specific JAK/STAT Target Genes inDrosophilaOptic Lobe Development  Journal Articles
• Evolution of Transcriptional Repressors Impacts Caenorhabditis Vulval Development  Journal Articles
• Evolution of the chaperonin families (HSP60, HSP 10 and TCP‐1) of proteins and the origin of eukaryotic cells  Journal Articles
• Expression of the β4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells  Journal Articles
• Fetal hemoglobin in sickle cell anemia: Genetic studies of the Arab-Indian haplotype  Journal Articles
• Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5′ olfactory receptor gene cluster  Journal Articles
• Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations  Journal Articles
• From p63 to p53 across p73  Journal Articles
• Functional implications of mutations within polyomavirus large T antigen Rb-binding domain: effects on pRb and p107 binding in vitro and immortalization activity in vivo  Journal Articles
• Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice  Journal Articles
• Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation  Journal Articles
• Gender, mutant p53 and PML: A growing “affaire” in tumor suppression and oncogenesis  Journal Articles
• Genetic Control of Vulval Development inCaenorhabditis briggsae  Journal Articles
• Genetic Dissection of Photoreceptor Subtype Specification by the Drosophila melanogaster Zinc Finger Proteins Elbow and No ocelli  Journal Articles
• Genomic Consequences of Background Effects onscallopedMutant Expressivity in the Wing ofDrosophila melanogaster  Journal Articles
• HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function  Journal Articles
• High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry  Journal Articles
• How well do you know your mutation? Complex effects of genetic background on expressivity, complementation, and ordering of allelic effects  Journal Articles
• Huntingtin contains a highly conserved nuclear export signal  Journal Articles
• Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity  Journal Articles
• Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1  Journal Articles
• Hypothesis: huntingtin may function in membrane association and vesicular traffickingThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Membrane Proteins in Health and Disease.  Conferences
• IL-15 Can Signal via IL-15Rα, JNK, and NF-κB To Drive RANTES Production by Myeloid Cells  Journal Articles
• Identification and Functional Characterization of a Novel Nuclear Localization Signal Present in the Yeast Nab2 Poly(A)⁺ RNA Binding Protein  Journal Articles
• Identification of Direct p73 Target Genes Combining DNA Microarray and Chromatin Immunoprecipitation Analyses  Journal Articles
• Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein  Journal Articles
• Identification of a novel Wee1 isoform  Journal Articles
• Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis  Journal Articles
• Induction of Mdm2 and enhancement of cell survival by bFGF  Journal Articles
• Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation  Journal Articles
• Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin  Journal Articles
• Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly-micromelia syndrome  Journal Articles
• Interaction of c-Abl and p73α and their collaboration to induce apoptosis  Journal Articles
• Interaction of mutant p53 with p73: A Surface Plasmon Resonance and Atomic Force Spectroscopy study  Journal Articles
• Investigation of FGFR2-IIIC Signaling via FGF-2 Ligand for Advancing GCT Stromal Cell Differentiation  Journal Articles
• Investigation on ERCC5 genetic polymorphisms and the development of gastric cancer in a Chinese population  Journal Articles
• Isolation of a novel gene from the DiGeorge syndrome critical region with homology to Drosophila gdl and to human LAMC1 genes  Journal Articles
• Kinase inhibitors modulate huntingtin cell localization and toxicity  Journal Articles
• Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein  Journal Articles
• Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness  Journal Articles
• Lethal Neonatal Rigidity and Multifocal Seizure Syndrome—A Misnamed Disorder?  Journal Articles
• Light and COP1 regulate level of overexpressed DET1 protein  Journal Articles
• Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions  Journal Articles
• Local Molecular Clocks in Three Nuclear Genes: Divergence Times for Rodents and Other Mammals and Incompatibility Among Fossil Calibrations  Conferences
• MRE11–RAD50–NBS1 and ATM function as co-mediators of TRF1 in telomere length control  Journal Articles
• MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability  Journal Articles
• Maturity Onset Diabetes in the Young (MODY) type 3.  Journal Articles
• Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation  Journal Articles
• Mitochondrial-matrix proteins at unexpected locations: are they exported?  Journal Articles
• Monoclonal Antibodies to Kaiso: A Novel Transcription Factor and p120^ctn-Binding Protein  Journal Articles
• Monoclonal antibodies raised against Xenopus p53 interact with human p73  Journal Articles
• Multiple Signaling Pathways Control the Activation of the CEF-4/9E3 Cytokine Gene by pp60v-  Journal Articles
• Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease  Journal Articles
• Mutations in the Chromatin Regulator Gene BRPF1 Cause Syndromic Intellectual Disability and Deficient Histone Acetylation  Journal Articles
• NR1D1 Recruitment to Sites of DNA Damage Inhibits Repair and Is Associated with Chemosensitivity of Breast Cancer  Journal Articles
• NSD1 mutations generate a genome-wide DNA methylation signature  Journal Articles
• Novel and recurrent EMD mutations in patients with Emery–Dreifuss muscular dystrophy, identify exon 2 as a mutation hot spot  Journal Articles
• Nuclear Import of Cdk/Cyclin Complexes: Identification of Distinct Mechanisms for Import of Cdk2/Cyclin E and Cdc2/Cyclin B1  Journal Articles
• Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-β  Journal Articles
• Nuclear import of the BTB/POZ transcriptional regulator Kaiso  Journal Articles
• Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease  Journal Articles
• Nudeocytoplasmic shuttling by protein nuclear import factors  Journal Articles
• Order of probe and nuclear protein extract addition can determine specificity of protein — DNA complexes in tested mobility shift assays  Journal Articles
• PML has a predictive role in tumor cell permissiveness to interferon-sensitive oncolytic viruses  Journal Articles
• PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop  Journal Articles
• PTEN inhibits BMI1 function independently of its phosphatase activity  Journal Articles
• Pathogenic variants in USP7 cause a neurodevelopmental disorder with speech delays, altered behavior, and neurologic anomalies  Journal Articles
• Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity  Journal Articles
• Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73  Journal Articles
• Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function  Journal Articles
• Polyglutamine-expanded ataxin-1 recruits Cu/Zn-superoxide dismutase into the nucleus of HeLa cells  Journal Articles
• Polyomavirus large T-antigen binds the ‘pRb related’ protein p130 through sequences in conserved region 2  Journal Articles
• Potential Biomarkers of Skeletal Muscle Damage  Journal Articles
• Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb  Journal Articles
• Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination  Journal Articles
• Proliferation of Normal and Malignant Human Epithelial Cells Post Irradiation  Journal Articles
• Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53  Journal Articles
• Proximodistal subdivision ofDrosophilalegs and wings: theelbow-no ocelligene complex  Journal Articles
• RNA association and nucleocytoplasmic shuttling by ataxin-1  Journal Articles
• RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization  Journal Articles
• Race, Ethnicity, and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer in the Randomized TAILORx Trial  Journal Articles
• Rapid Evolution of the Sex-Determining Gene, transformer: Structural Diversity and Rate Heterogeneity Among Sibling Species of Drosophila  Journal Articles
• Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor α and liver-X-receptor α  Journal Articles
• Recurrent genomic rearrangements in primary testicular lymphoma.  Journal Articles
• Reduced host cell reactivation of oxidative DNA damage in human cells deficient in the mismatch repair gene hMSH2  Journal Articles
• Relationship Between Transcription Factors and S14 Gene Expression in Response to Thyroid Hormone and Age  Journal Articles
• Role for Retinoblastoma Protein Family Members in UV-enhanced Expression from the Human Cytomegalovirus Immediate Early Promoter¶  Journal Articles
• Role of cis-acting elements in the control of SERCA2b Ca2+ pump mRNA decay by nuclear proteins  Journal Articles
• Rtt107 Is Required for Recruitment of the SMC5/6 Complex to DNA Double Strand Breaks  Journal Articles
• S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation  Journal Articles
• SOX2 Functions to Maintain Neural Progenitor Identity  Journal Articles
• SOX2, a Persistent Marker for Multipotential Neural Stem Cells Derived from Embryonic Stem Cells, the Embryo or the Adult  Journal Articles
• SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation.  Journal Articles
• Sequence and structural homology between a mouse T-complex protein TCP-1 and the 'chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins.  Journal Articles
• Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells  Journal Articles
• Sex Identification of Elk (Cervus elaphus canadensis), Moose (Alces alces), and White-Tailed Deer (Odocoileus virginianus) Using the Polymerase Chain Reaction  Journal Articles
• Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice  Journal Articles
• Silencing of Mustn1 inhibits myogenic fusion and differentiation  Journal Articles
• Skeletal muscle regeneration is delayed by reduction in Xin expression: consequence of impaired satellite cell activation?  Journal Articles
• Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation  Journal Articles
• Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells  Journal Articles
• Spliceosome malfunction causes neurodevelopmental disorders with overlapping features  Journal Articles
• Structural Organization of the WD repeat protein-encoding gene HIRA in the DiGeorge syndrome critical region of human chromosome 22.  Journal Articles
• TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma  Journal Articles
• Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology  Journal Articles
• Telomere maintenance by telomerase and by recombination can coexist in human cells  Journal Articles
• The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals  Journal Articles
• The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2  Journal Articles
• The Catenin p120^ctn Interacts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor  Journal Articles
• The Drosophila Gene RanBPM Functions in the Mushroom Body to Regulate Larval Behavior  Journal Articles
• The Drosophila centrosome-associated protein CP190 is essential for viability but not for cell division.  Journal Articles
• The Hippo tumor suppressor pathway: a report on ‘the second workshop on the Hippo tumor suppressor pathway’  Journal Articles
• The Human Tap Nuclear RNA Export Factor Contains a Novel Transportin-dependent Nuclear Localization Signal That Lacks Nuclear Export Signal Function  Journal Articles
• The MAGE proteins: Emerging roles in cell cycle progression, apoptosis, and neurogenetic disease  Journal Articles
• The Nup107-160 complex and γ-TuRC regulate microtubule polymerization at kinetochores  Journal Articles
• The Transcriptional Coactivator Yes-Associated Protein Drives p73 Gene-Target Specificity in Response to DNA Damage  Journal Articles
• The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation  Journal Articles
• The association of HBG2, BCL11A, and HMIP polymorphisms with fetal hemoglobin and clinical phenotype in Iraqi Kurds with sickle cell disease  Journal Articles
• The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance  Journal Articles
• The disruption of the protein complex mutantp53/p73 increases selectively the response of tumor cells to anticancer drugs  Journal Articles
• The genetic basis of asymptomatic codon 8 frame‐shift (HBB:c25_26delAA) β⁰‐thalassaemia homozygotes  Journal Articles
• The genetics of hemoglobin A₂ regulation in sickle cell anemia  Journal Articles
• The hereditary adult-onset ataxias in South Africa  Journal Articles
• The pathobiology of salivary gland  Journal Articles
• The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo  Journal Articles
• The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults  Journal Articles
• The role of TWIST as a regulator in giant cell tumor of bone  Journal Articles
• The transcriptional cofactor Lbh regulates angiogenesis and endochondral bone formation during fetal bone development  Journal Articles
• Transactivation by PPAR/RXR heterodimers in yeast is potentiated by exogenous fatty acid via a pathway requiring intact peroxisomes.  Journal Articles
• Transcriptional regulation of the Drosophila melanogaster muscle myosin heavy-chain gene.  Journal Articles
• Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73  Journal Articles
• Up-regulation of CIR1/CROC1 expression upon cell immortalization and in tumor-derived human cell lines  Journal Articles
• Xin Is a Marker of Skeletal Muscle Damage Severity in Myopathies  Journal Articles
• Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers  Journal Articles
• Xin‐deficient mice display myopathy, impaired contractility, attenuated muscle repair and altered satellite cell functionality  Journal Articles
• YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer  Journal Articles
• YAP1 Meets Tumor Suppression  Journal Articles
• YAP: At the crossroad between transformation and tumor suppression  Journal Articles
• [Expressions of cytoprotective proteins for human renal allografts].  Journal Articles
• p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor  Journal Articles
• p73 Is Regulated by Phosphorylation at the G2/M Transition  Journal Articles
• p73 and p63: Why Do We Still Need Them?  Journal Articles
• p73-Mediated Chemosensitivity: A Preferential Target of Oncogenic Mutant p53  Journal Articles
• p73-induced apoptosis: A question of compartments and cooperation  Journal Articles
• ΔN-p73 is a transcriptional target of the PML/RARα oncogene in myeloid differentiation  Journal Articles
• δEF1 repressor controls selectively p53 family members during differentiation  Journal Articles