Nuclear Proteins Concept

subject area of

• A Novel Double-stranded RNA-binding Protein, Disco Interacting Protein 1 (DIP1), Contributes to Cell Fate Decisions during Drosophila Development  Academic Article
• A Role of p73 in Mitotic Exit  Academic Article
• A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia  Academic Article
• A mitochondrial ketogenic enzyme regulates its gene expression by association with the nuclear hormone receptor PPARα  Academic Article
• A novel GFP reporter mouse revealsMustn1expression in adult regenerating skeletal muscle, activated satellite cells and differentiating myoblasts  Academic Article
• A patient-derived cellular model for Huntington’s disease reveals phenotypes at clinically relevant CAG lengths  Academic Article
• A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy  Academic Article
• ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence  Academic Article
• Absence of p21CIP Rescues Myogenic Progenitor Cell Proliferative and Regenerative Capacity in Foxk1 Null Mice  Academic Article
• Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor α are altered by the centrosome-associated protein CAP350  Academic Article
• All colonies of CHO-K1 cells surviving γ-irradiation contain non-viable cells  Academic Article
• An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein  Academic Article
• Analysis of human MDM4 variants in papillary thyroid carcinomas reveals new potential markers of cancer properties  Academic Article
• Analysis of p73 expression pattern in acute myeloid leukemias: lack of ΔN-p73 expression is a frequent feature of acute promyelocytic leukemia  Academic Article
• BAFopathies’ DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin–Siris and Nicolaides–Baraitser syndromes  Academic Article
• BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia  Academic Article
• BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies  Academic Article
• BCL11A represses HBG transcription in K562 cells  Academic Article
• BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation  Academic Article
• Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells  Academic Article
• Bmi1 promotes prostate tumorigenesis via inhibiting p16INK4A and p14ARF expression  Academic Article
• Canadian Association of Neurosciences Review: Polyglutamine Expansion Neurodegenerative Diseases  Academic Article
• Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres  Academic Article
• Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins.  Academic Article
• Cellular and Molecular Regulation of Skeletal Muscle Side Population Cells  Academic Article
• Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73  Academic Article
• Characterization of SERCA2b Ca2+–Mg2+ ATPase mRNA decay by nuclear proteins  Academic Article
• Characterization of the mouse lysosomal sialidase promoter  Academic Article
• Che-1 Promotes Tumor Cell Survival by Sustaining Mutant p53 Transcription and Inhibiting DNA Damage Response Activation  Academic Article
• Chromosome content and ultrastructure of radiation-induced micronuclei  Academic Article
• Clinical features of facioscapulohumeral muscular dystrophy 2  Academic Article
• Cloning of a Chinese hamster protein homologous to the mouse t-complex protein TCP-1: Structural similarity to the ubiquitous ‘chaperonin’ family of heat-shock proteins  Academic Article
• Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas  Academic Article
• Compromised genomic integrity impedes muscle growth after Atrx inactivation  Academic Article
• Control of Centromere Localization of the MEI-S332 Cohesion Protection Protein  Academic Article
• Control of SERCA2a Ca2+ pump mRNA stability by nuclear proteins: role of domains in the 3′-untranslated region  Academic Article
• Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers  Academic Article
• CtIP/Ctp1/Sae2, molecular form fit for function  Academic Article
• Culture of human esophageal endoscopic biopsies  Academic Article
• Cytogenetic Prognostication Within Medulloblastoma Subgroups  Academic Article
• Cytosolic localization of Fox proteins in motor neurons of G93A SOD1 mice  Academic Article
• DNA Damage-Dependent Acetylation of p73 Dictates the Selective Activation of Apoptotic Target Genes  Academic Article
• DNp73α protects myogenic cells from apoptosis  Academic Article
• Definition of a Consensus Transportin-specific Nucleocytoplasmic Transport Signal  Academic Article
• Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes  Academic Article
• Detection of an Involvement of the Human Mismatch Repair Genes hMLH1 and hMSH2 in Nucleotide Excision Repair Is Dependent on UVC Fluence to Cells  Academic Article
• Determination of the Functional Domain Organization of the Importin α Nuclear Import Factor  Academic Article
• Drosophila ELYS regulates Dorsal dynamics during development  Academic Article
• EMSY and CCND1 amplification in familial breast cancer: from the Ontario site of the Breast Cancer Family Registry  Academic Article
• Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches  Academic Article
• Endometriosis-Associated Ovarian Carcinomas  Academic Article
• Enhanced cell-free transcription of the ribosomal protein L32 gene by the polyoma virus enhancer PEA3 DNA-binding protein  Academic Article
• Enhancing Endocrine Therapy Combination Strategies for the Treatment of Postmenopausal HR+/HER2– Advanced Breast Cancer  Academic Article
• Evidence for Tissue-Specific JAK/STAT Target Genes in Drosophila Optic Lobe Development  Academic Article
• Evolution of Transcriptional Repressors Impacts Caenorhabditis Vulval Development  Academic Article
• Evolution of the chaperonin families (HSP60, HSP 10 and TCP-1) of proteins and the origin of eukaryotic cells  Academic Article
• Expression of the β4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells  Academic Article
• Fetal hemoglobin in sickle cell anemia: Genetic studies of the Arab-Indian haplotype  Academic Article
• Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5′ olfactory receptor gene cluster  Academic Article
• Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations  Academic Article
• From p63 to p53 across p73  Academic Article
• Functional implications of mutations within polyomavirus large T antigen Rb-binding domain: effects on pRb and p107 binding in vitro and immortalization activity in vivo  Academic Article
• Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice  Academic Article
• Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation  Academic Article
• Gender, mutant p53 and PML: A growing “affaire” in tumor suppression and oncogenesis  Academic Article
• Genetic Control of Vulval Development inCaenorhabditis briggsae  Academic Article
• Genetic Dissection of Photoreceptor Subtype Specification by the Drosophila melanogaster Zinc Finger Proteins Elbow and No ocelli  Academic Article
• Genomic Consequences of Background Effects on scalloped Mutant Expressivity in the Wing of Drosophila melanogaster  Academic Article
• HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function  Academic Article
• High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry  Academic Article
• How well do you know your mutation? Complex effects of genetic background on expressivity, complementation, and ordering of allelic effects  Academic Article
• Huntingtin contains a highly conserved nuclear export signal  Academic Article
• Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity  Academic Article
• Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1  Academic Article
• Hypothesis: huntingtin may function in membrane association and vesicular traffickingThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Membrane Proteins in Health and Disease.  Conference Paper
• IL-15 Can Signal via IL-15Rα, JNK, and NF-κB To Drive RANTES Production by Myeloid Cells  Academic Article
• Identification and Functional Characterization of a Novel Nuclear Localization Signal Present in the Yeast Nab2 Poly(A) ⁺ RNA Binding Protein  Academic Article
• Identification and characterization of RED120: A conserved PWI domain protein with links to splicing and 3′-end formation  Academic Article
• Identification of Direct p73 Target Genes Combining DNA Microarray and Chromatin Immunoprecipitation Analyses  Academic Article
• Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein  Academic Article
• Identification of a novel Wee1 isoform  Academic Article
• Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis  Academic Article
• Immunoreactivity of the phosphorylated axonal neurofilament H subunit (pNF-H) in blood of ALS model rodents and ALS patients: evaluation of blood pNF-H as a potential ALS biomarker  Academic Article
• Induction of Mdm2 and enhancement of cell survival by bFGF  Academic Article
• Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation  Academic Article
• Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin  Academic Article
• Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly-micromelia syndrome  Academic Article
• Interaction of c-Abl and p73α and their collaboration to induce apoptosis  Academic Article
• Interaction of mutant p53 with p73: A Surface Plasmon Resonance and Atomic Force Spectroscopy study  Academic Article
• Investigation of FGFR2-IIIC Signaling via FGF-2 Ligand for Advancing GCT Stromal Cell Differentiation  Academic Article
• Investigation on ERCC5 genetic polymorphisms and the development of gastric cancer in a Chinese population  Academic Article
• Isolation of a novel gene from the DiGeorge syndrome critical region with homology to Drosophila gdl and to human LAMC1 genes  Academic Article
• Kinase inhibitors modulate huntingtin cell localization and toxicity  Academic Article
• Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein  Academic Article
• Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness  Academic Article
• Lethal Neonatal Rigidity and Multifocal Seizure Syndrome—A Misnamed Disorder?  Academic Article
• Light and COP1 regulate level of overexpressed DET1 protein  Academic Article
• Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions  Academic Article
• Local Molecular Clocks in Three Nuclear Genes: Divergence Times for Rodents and Other Mammals and Incompatibility Among Fossil Calibrations  Conference Paper
• MCM Proteins Are Associated with RNA Polymerase II Holoenzyme  Academic Article
• MIB-1 Proliferative Activity Is a Significant Prognostic Factor in Primary Thick Cutaneous Melanomas  Academic Article
• MRE11–RAD50–NBS1 and ATM function as co-mediators of TRF1 in telomere length control  Academic Article
• Maturity Onset Diabetes in the Young (MODY) type 3.  Academic Article
• Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation  Academic Article
• Mitochondrial-matrix proteins at unexpected locations: are they exported?  Academic Article
• Monoclonal Antibodies to Kaiso: A Novel Transcription Factor and p120^ctn-Binding Protein  Academic Article
• Monoclonal antibodies raised against Xenopus p53 interact with human p73  Academic Article
• Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15  Academic Article
• Multiple Signaling Pathways Control the Activation of the CEF-4/9E3 Cytokine Gene by pp60v-  Academic Article
• Multiple interactions between SRm160 and SR family proteins in enhancer-dependent splicing and development of C. elegans  Academic Article
• Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease  Academic Article
• Mutations in the Chromatin Regulator Gene BRPF1 Cause Syndromic Intellectual Disability and Deficient Histone Acetylation  Academic Article
• NSD1 mutations generate a genome-wide DNA methylation signature  Academic Article
• Novel and recurrent EMD mutations in patients with Emery–Dreifuss muscular dystrophy, identify exon 2 as a mutation hot spot  Academic Article
• Nuclear Import of Cdk/Cyclin Complexes: Identification of Distinct Mechanisms for Import of Cdk2/Cyclin E and Cdc2/Cyclin B1  Academic Article
• Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-beta  Academic Article
• Nuclear import of the BTB/POZ transcriptional regulator Kaiso  Academic Article
• Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease  Academic Article
• Nudeocytoplasmic shuttling by protein nuclear import factors  Academic Article
• Order of probe and nuclear protein extract addition can determine specificity of protein — DNA complexes in tested mobility shift assays  Academic Article
• PML has a predictive role in tumor cell permissiveness to interferon-sensitive oncolytic viruses  Academic Article
• PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop  Academic Article
• PTEN inhibits BMI1 function independently of its phosphatase activity  Academic Article
• Pathogenic variants in USP7 cause a neurodevelopmental disorder with speech delays, altered behavior, and neurologic anomalies  Academic Article
• Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity  Academic Article
• Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73  Academic Article
• Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function  Academic Article
• Polyomavirus large T-antigen binds the ‘pRb related’ protein p130 through sequences in conserved region 2  Academic Article
• Potential biomarkers of skeletal muscle damage  Academic Article
• Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb  Academic Article
• Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination  Academic Article
• Proliferation of Normal and Malignant Human Epithelial Cells Post Irradiation  Academic Article
• Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53  Academic Article
• Proteomic Analysis of SRm160-containing Complexes Reveals a Conserved Association with Cohesin  Academic Article
• Proximodistal subdivision ofDrosophilalegs and wings: theelbow-no ocelligene complex  Academic Article
• RNA association and nucleocytoplasmic shuttling by ataxin-1  Academic Article
• RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization  Academic Article
• Race, Ethnicity, and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer in the Randomized TAILORx Trial  Academic Article
• Rapid Evolution of the Sex-Determining Gene, transformer: Structural Diversity and Rate Heterogeneity Among Sibling Species of Drosophila  Academic Article
• Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor α and liver-X-receptor α  Academic Article
• Reduced host cell reactivation of oxidative DNA damage in human cells deficient in the mismatch repair gene hMSH2  Academic Article
• Regions Flanking Exon 1 Regulate Constitutive Expression of the Human Antithrombin Gene  Academic Article
• Relationship Between Transcription Factors and S14 Gene Expression in Response to Thyroid Hormone and Age  Academic Article
• Role for Retinoblastoma Protein Family Members in UV-enhanced Expression from the Human Cytomegalovirus Immediate Early Promoter¶  Academic Article
• Role of cis-acting elements in the control of SERCA2b Ca2+ pump mRNA decay by nuclear proteins  Academic Article
• Rtt107 Is Required for Recruitment of the SMC5/6 Complex to DNA Double Strand Breaks  Academic Article
• S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation  Academic Article
• SR-related proteins and the processing of messenger RNA precursors.  Conference Paper
• SRm160 Splicing Coactivator Promotes Transcript 3′-End Cleavage  Academic Article
• Sequence and structural homology between a mouse T-complex protein TCP-1 and the 'chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins.  Academic Article
• Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells  Academic Article
• Sex Identification of Elk (Cervus elaphus canadensis), Moose (Alces alces), and White-Tailed Deer (Odocoileus virginianus) Using the Polymerase Chain Reaction  Academic Article
• Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice  Academic Article
• Silencing of Mustn1 inhibits myogenic fusion and differentiation  Academic Article
• Skeletal muscle regeneration is delayed by reduction in Xin expression: consequence of impaired satellite cell activation?  Academic Article
• Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation  Academic Article
• Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells  Academic Article
• Splicing and transcription-associated proteins PSF and p54nrb/NonO bind to the RNA polymerase II CTD  Academic Article
• Structural Organization of the WD repeat protein-encoding gene HIRA in the DiGeorge syndrome critical region of human chromosome 22.  Academic Article
• TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma  Academic Article
• Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology  Academic Article
• Telomere maintenance by telomerase and by recombination can coexist in human cells  Academic Article
• The Acute Myeloid Leukemia-Associated Protein, Dek, Forms a Splicing-Dependent Interaction with Exon-Product Complexes  Academic Article
• The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals  Academic Article
• The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2  Academic Article
• The Catenin p120 ^ctn Interacts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor  Academic Article
• The Drosophila Gene RanBPM Functions in the Mushroom Body to Regulate Larval Behavior  Academic Article
• The Hippo tumor suppressor pathway: a report on ‘the second workshop on the Hippo tumor suppressor pathway’  Academic Article
• The Human Tap Nuclear RNA Export Factor Contains a Novel Transportin-dependent Nuclear Localization Signal That Lacks Nuclear Export Signal Function  Academic Article
• The MAGE proteins: Emerging roles in cell cycle progression, apoptosis, and neurogenetic disease  Academic Article
• The Nup107-160 complex and γ-TuRC regulate microtubule polymerization at kinetochores  Academic Article
• The Transcriptional Coactivator Yes-Associated Protein Drives p73 Gene-Target Specificity in Response to DNA Damage  Academic Article
• The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation  Academic Article
• The association of HBG2 , BCL11A, and HMIP polymorphisms with fetal hemoglobin and clinical phenotype in Iraqi Kurds with sickle cell disease  Academic Article
• The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance  Academic Article
• The disruption of the protein complex mutantp53/p73 increases selectively the response of tumor cells to anticancer drugs  Academic Article
• The genetic basis of asymptomatic codon 8 frame-shift (HBB:c25_26delAA) β⁰-thalassaemia homozygotes  Academic Article
• The genetics of hemoglobin A₂regulation in sickle cell anemia  Academic Article
• The pathobiology of salivary gland  Academic Article
• The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo  Academic Article
• The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults  Academic Article
• The role of TWIST as a regulator in giant cell tumor of bone  Academic Article
• The transcriptional cofactor Lbh regulates angiogenesis and endochondral bone formation during fetal bone development  Academic Article
• Transactivation by PPAR/RXR heterodimers in yeast is potentiated by exogenous fatty acid via a pathway requiring intact peroxisomes.  Academic Article
• Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73  Academic Article
• Up-regulation of CIR1/CROC1 expression upon cell immortalization and in tumor-derived human cell lines  Academic Article
• Xin Is a Marker of Skeletal Muscle Damage Severity in Myopathies  Academic Article
• Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers  Academic Article
• Xin-deficient mice display myopathy, impaired contractility, attenuated muscle repair and altered satellite cell functionality  Academic Article
• YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer  Academic Article
• YAP1 Meets Tumor Suppression  Academic Article
• YAP: At the crossroad between transformation and tumor suppression  Academic Article
• p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor  Academic Article
• p73 Is Regulated by Phosphorylation at the G2/M Transition  Academic Article
• p73 and p63: Why Do We Still Need Them?  Academic Article
• p73-Mediated Chemosensitivity: A Preferential Target of Oncogenic Mutant p53  Academic Article
• p73-induced apoptosis: A question of compartments and cooperation  Academic Article
• ΔN-p73 is a transcriptional target of the PML/RARα oncogene in myeloid differentiation  Academic Article
• δEF1 repressor controls selectively p53 family members during differentiation  Academic Article