The Nup107-160 complex and γ-TuRC regulate...

The Nup107-160 complex and γ-TuRC regulate microtubule polymerization at kinetochores

Abstract

The γ-tubulin ring complex (γ-TuRC) nucleates microtubules. The nuclear pore subcomplex Nup107-160 is found to interact and cooperate with γ-TuRC to nucleate microtubules at kinetochores, thereby promoting spindle assembly.

Authors

Mishra RK; Chakraborty P; Arnaoutov A; Fontoura BMA; Dasso M

Journal

Nature Cell Biology, Vol. 12, No. 2, pp. 164–169

Publisher

Springer Nature

Publication Date

February 1, 2010

DOI

10.1038/ncb2016

ISSN

1465-7392

Associated Experts

Ram Mishra

Director, Faculty of Engineering

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