DNA Damage
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Id2gene is a transcriptional target of the protein complex mutant p53/E2F1 Academic Article
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A Novel Aspect of Tumorigenesis—BMI1 Functions in Regulating DNA Damage Response Academic Article
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A Novel Non-canonical Forkhead-associated (FHA) Domain-binding Interface Mediates the Interaction between Rad53 and Dbf4 Proteins Academic Article
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A Role of p73 in Mitotic Exit Academic Article
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A Two-Species Biomarker Model for the Assessment of Sediment Toxicity in the Marine and Estuarine Environment Using the Comet Assay Academic Article
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A combination of MSH2 DNA mismatch repair deficiency and expression of the SV40 large T antigen results in cisplatin resistance of mouse embryonic fibroblasts Academic Article
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A comparative approach using biomarkers in feral and caged Neotropical fish: Implications for biomonitoring freshwater ecosystems in agricultural areas Academic Article
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A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria Academic Article
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A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance Academic Article
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A preliminary analysis of the DNA and diet of the extinct Beothuk: A systematic approach to ancient human DNA Academic Article
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A unifying mechanism in neurodegeneration Academic Article
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AMP-activated protein kinase (AMPK) beyond metabolism Academic Article
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APE2 Zf-GRF facilitates 3′-5′ resection of DNA damage following oxidative stress Academic Article
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ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres Academic Article
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Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents. Academic Article
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Accelerated decline in lung function in cigarette smokers is associated with TP53/MDM2 polymorphisms Academic Article
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Actions of radiation on living cells in the “post-bystander” era Academic Article
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Adaptation in bacterial CRISPR-Cas immunity can be driven by defective phages Academic Article
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Adaptive response in frogs chronically exposed to low doses of ionizing radiation in the environment Academic Article
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Aging, oxidative responses, and proliferative capacity in cultured mouse aortic smooth muscle cells Academic Article
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Air pollution induces heritable DNA mutations Academic Article
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Analysis of DNA repair in XP–HeLa hybrids; lack of correlation between excision repair of u.v. damage and adenovirus reactivation in an XP(D)-like cell line Academic Article
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Antioxidant responses in different body regions of the polychaeta Laeonereis acuta (Nereididae) exposed to copper Academic Article
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Application of public-domain statistical analysis software for evaluation and comparison of comet assay data Academic Article
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Assessment of DNA Oxidation and Antioxidant Activity in Hypertensive Patients with Chronic Kidney Disease Academic Article
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BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation Academic Article
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Benign tumors from the human nervous system express high levels of survivin and are resistant to spontaneous and radiation-induced apoptosis Academic Article
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Biomarkers in croakers Micropogonias furnieri (Teleostei: Sciaenidae) from polluted and non-polluted areas from the Patos Lagoon estuary (Southern Brazil): Evidences of genotoxic and immunological effects Academic Article
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Biomarkers of exposure and effect in the Brazilian flounder Paralichthys orbignyanus (Teleostei: Paralichthyidae) from the Patos Lagoon estuary (Southern Brazil) Academic Article
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Biomarkers of waterborne copper exposure in the guppy Poecilia vivipara acclimated to salt water Academic Article
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Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair Academic Article
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Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation Academic Article
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Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation Academic Article
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Bystander Effects in Repair-Deficient Cell Lines Academic Article
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Calculation of radiation-induced DNA damage from photons and tritium beta-particles Academic Article
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Calculation of radiation-induced DNA damage from photons and tritium beta-particles Academic Article
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Camptothecin-resistant mutants of Chinese hamster ovary cells containing a resistant form of topoisomerase I. Academic Article
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Cdk-dependent phosphorylation regulates TRF1 recruitment to PML bodies and promotes C-circle production in ALT cells Academic Article
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Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins. Academic Article
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Cellular responses in rainbow trout (Oncorhynchus mykiss) reared in tritiated water and/or fed organically bound tritium Academic Article
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Changing paradigms in radiobiology Academic Article
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Che-1 Promotes Tumor Cell Survival by Sustaining Mutant p53 Transcription and Inhibiting DNA Damage Response Activation Academic Article
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Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53 Academic Article
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Chromosomal damage induced by human adenovirus type 12 requires expression of the E1B 55-kilodalton viral protein Academic Article
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Cockayne syndrome group B protein regulates
DNA
double‐strand break repair and checkpoint activation Academic Article
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Comment on "Whole-Genome Shotgun Sequencing of Mitochondria from Ancient Hair Shafts" Academic Article
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Compromised genomic integrity impedes muscle growth after Atrx inactivation Academic Article
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Contributions of DNA Damage to Alzheimer’s Disease Academic Article
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Copper effects on biomarkers associated with photosynthesis, oxidative status and calcification in the Brazilian coral Mussismilia harttii (Scleractinia, Mussidae) Academic Article
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Correlated responses for DNA damage, phagocytosis activity and lysosomal function revealed in a comparison between field and laboratory studies: Fathead minnow exposed to tritium Academic Article
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Cross-resistance to photofrin-mediated photodynamic therapy and UV light and recovery from photodynamic therapy damage in Rif-8A mouse fibrosarcoma cells measured using viral capacity Academic Article
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Crystallization of the DdrB–DNA complex fromDeinococcus radiodurans Academic Article
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Cytogenetic dose–response and adaptive response in cells of ungulate species exposed to ionizing radiation Academic Article
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DNA Damage Repair in Huntington’s Disease and Other Neurodegenerative Diseases Academic Article
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DNA Damage and Biological Expression of Adenovirus: A Comparison of Liquid versus Frozen Conditions of Exposure to γ Rays Academic Article
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DNA Damage-Dependent Acetylation of p73 Dictates the Selective Activation of Apoptotic Target Genes Academic Article
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DNA Lesions That Signal the Induction of Radioresistance and DNA Repair in Yeast Academic Article
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DNA Repair Signaling of Huntingtin: The Next Link Between Late-Onset Neurodegenerative Disease and Oxidative DNA Damage Academic Article
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DNA damage in bipolar disorder Academic Article
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DNA damage in rats after treatment with methylphenidate Academic Article
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Deciphering and simulating models of radiation genotoxicity with CRISPR/Cas9 systems Academic Article
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Defective repair of UV-damaged DNA in human tumor and SV40-transformed human cells but not in adenovirus-transformed human cells Academic Article
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Deficient base excision repair of oxidative DNA damage induced by methylene blue plus visible light in xeroderma pigmentosum group C fibroblasts Academic Article
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Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes Academic Article
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Delayed cell death and bystander effects in the progeny of Chinook Salmon Embryo cells exposed to radiation and a range of aquatic pollutants Academic Article
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Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment Academic Article
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Depletion of poly(ADP-ribose) polymerase-1 reduces host cell reactivation of a UV-damaged adenovirus-encoded reporter gene in human dermal fibroblasts Academic Article
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Differential contribution of XPC, RAD23A, RAD23B and CENTRIN 2 to the UV-response in human cells Academic Article
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Differential effects of hypoxia and acidosis on p53 expression, repair of UVC-damaged DNA and viability after UVC in normal and tumor-derived human cells Academic Article
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Direct and delayed X-ray-induced DNA damage in male mouse germ cells Academic Article
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ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53 Academic Article
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ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function Academic Article
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ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response. Academic Article
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ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation Academic Article
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Early host cell reactivation of an oxidatively damaged adenovirus-encoded reporter gene requires the Cockayne syndrome proteins CSA and CSB Academic Article
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Effects of mood stabilizers on DNA damage in an animal model of mania. Academic Article
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Efficient UV repair requires disengagement of the CSB winged helix domain from the CSB ATPase domain Academic Article
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Elevated DNA damage in a mouse model of oxidative stress: impacts of ionizing radiation and a protective dietary supplement Academic Article
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Elevated G2 chromosomal radiosensitivity in Irish breast cancer patients: a comparison with other studies Academic Article
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Endonuclease III and endonuclease IV protect Escherichia coli from the lethal and mutagenic effects of near-UV irradiation Academic Article
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Enhanced expression from the human cytomegalovirus immediate-early promoter in a non-replicating adenovirus encoded reporter gene following cellular exposure to chemical DNA damaging agents Academic Article
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Enhanced host cell reactivation of a UV-damaged reporter gene in pre-UV-treated cells is delayed in Cockayne syndrome cells Academic Article
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Evidence for lack of mitochondrial DNA repair followingcis-dichlorodiammineplatinum treatment Academic Article
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Exercise-induced protection of bone marrow cells following exposure to radiation Academic Article
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Expression of an adenovirus encoded reporter gene and its reactivation following UVC and oxidative damage in cultured fish cells Academic Article
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Expression of delayed toxicity and lethal mutations in the progeny of human cells surviving exposure to radiation and other environmental mutagens Conference Paper
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Extracellular Signal-Regulated Kinases Modulate DNA Damage Response - A Contributing Factor to Using MEK Inhibitors in Cancer Therapy Academic Article
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Fanconi’s Anemia Effect or Sickle Cell Anemia Effect: That is the Question Academic Article
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From p63 to p53 across p73 Academic Article
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Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression Academic Article
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Gain of function of mutant p53: The mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation Academic Article
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Generation of a new adenovirus type 12-inducible fragile site by insertion of an artificial U2 locus in the human genome. Academic Article
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Genetic Analyses from Ancient DNA Academic Article
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Genetic and Chemical Screening in Human Blood Serum Reveals Unique Antibacterial Targets and Compounds against Klebsiella pneumoniae Academic Article
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Genetic and biochemical effects induced by iron ore, Fe and Mn exposure in tadpoles of the bullfrog Lithobates catesbeianus Academic Article
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Genomic instability, bystander effects and radiation risks: implications for development of protection strategies for man and the environment. Academic Article
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Genotoxicity of field-collected inter-tidal sediments from Cork Harbor, Ireland, to juvenile turbot (Scophthalmus maximus L.) as measured by the Comet assay Academic Article
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HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function Academic Article
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Heat-induced thermal tolerance and radiation resistance to apoptosis in human lymphocytes Academic Article
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Hepatic biomarkers of sediment-associated pollution in juvenile turbot, Scophthalmus maximus L. Academic Article
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High-Accuracy Relative Biological Effectiveness Values Following Low-Dose Thermal Neutron Exposures Support Bimodal Quality Factor Response with Neutron Energy Academic Article
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Host cell reactivation of gene expression for an adenovirus-encoded reporter gene reflects the repair of UVC-induced cyclobutane pyrimidine dimers and methylene blue plus visible light-induced 8-oxoguanine Academic Article
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Host cell reactivation of irradiated adenovirus in UV-sensitive Chinese hamster ovary cell mutants Academic Article
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Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex Academic Article
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Implications of seasonal priming and reproductive activity on the interpretation of Comet assay data derived from the clam, Tapes semidecussatus Reeves 1864, exposed to contaminated sediments Academic Article
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Increased expression of p53 enhances transcription-coupled repair and global genomic repair of a UVC-damaged reporter gene in human cells Academic Article
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Increased oxidative stress and DNA damage in bipolar disorder: A twin-case report Academic Article
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Indirect stimulation of recombination in Escherichia coli K-12: dependence on recJ, uvrA, and uvrD Academic Article
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Induction of Mdm2 and enhancement of cell survival by bFGF Academic Article
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Inhibition of RNA polymerase II as a trigger for the p53 response Academic Article
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Inhibition of p53 Transcriptional Activity by Bcl-2 Requires Its Membrane-anchoring Domain Academic Article
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Initiation of Apoptosis in Cells Exposed to Medium from the Progeny of Irradiated Cells: A Possible Mechanism for Bystander-Induced Genomic Instability? Academic Article
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Low-dose metronomic delivery of cyclophosphamide is less detrimental to granulosa cell viability, ovarian function, and fertility than maximum tolerated dose delivery in the mouse† Academic Article
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Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity Academic Article
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Mathematical model for the cancer stem cell hypothesis Academic Article
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Mechanisms and implications of genomic instability and other delayed effects of ionizing radiation exposure Academic Article
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Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation Academic Article
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Menin Is a Regulator of the Stress Response in
Drosophila melanogaster Academic Article
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Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain Academic Article
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Microvesicles Contribute to the Bystander Effect of DNA Damage Academic Article
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Mitochondrial DNA damage by anticancer agents Academic Article
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Mitochondrial DNA point mutations and a novel deletion induced by direct low-LET radiation and by medium from irradiated cells Academic Article
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Mitochondrio‐nuclear translocation of AIF in apoptosis and necrosis Academic Article
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Modelling DNA damage induced by different energy photons and tritium beta-particles Academic Article
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Modulation of Radiation Responses by Pre-exposure to Irradiated Cell Conditioned Medium Academic Article
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Modulation of radiation-induced strand break repair by cisplatin in mammalian cells Academic Article
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Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop Academic Article
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N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation Academic Article
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Neutron and Cobalt-60 γ Irradiation Produce Similar Changes in DNA Supercoiling Academic Article
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New insights from old bones: DNA preservation and degradation in permafrost preserved mammoth remains Academic Article
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Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance Academic Article
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Non-cancer health effects of pesticides: systematic review and implications for family doctors. Academic Article
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Noninvasive Markers of Oxidative DNA Stress, RNA Degradation and Protein Degradation Are Differentially Correlated With Resting Metabolic Rate and Energy Intake in Children and Adolescents Academic Article
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Nucleotide excision repair in the human ovarian carcinoma cell line (2008) and its cisplatin-resistant variant (C13*) Academic Article
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On the Road to Bacterial Cell Death Academic Article
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Open-Source High-Throughput Phenomics of Bacterial Promoter-Reporter Strains Academic Article
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Oxidative ecology of paternal care in wild smallmouth bass, Micropterus dolomieu Academic Article
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Oxidative stress and DNA damage responses to phenanthrene exposure in the estuarine guppy Poecilia vivipara Academic Article
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Oxidative stress and the mitochondrial theory of aging in human skeletal muscle Academic Article
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Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts Academic Article
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Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells Academic Article
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Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis Academic Article
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Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function Academic Article
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Placental Transforming Growth Factor-β Is a Downstream Mediator of the Growth Arrest and Apoptotic Response of Tumor Cells to DNA Damage and p53 Overexpression Academic Article
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Poly(ADP-ribose) polymerase can bind melphalan damaged DNA. Academic Article
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Poly(ADP-ribose) polymerase-1, DNA repair and mammalian longevity Academic Article
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Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53 Academic Article
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Prostate cancer stem-like cells proliferate slowly and resist etoposide-induced cytotoxicity via enhancing DNA damage response Academic Article
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Quantifying murine bone marrow and blood radiation dose response following 18F-FDG PET with DNA damage biomarkers Academic Article
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RELATIVE REPAIR OF ADENOVIRUS DAMAGED BY SUNLAMP, UV AND γ-IRRADIATION IN COCKAYNE SYNDROME FIBROBLASTS IS DIFFERENT FROM THAT IN XERODERMA PIGMENTOSUM FIBROBLASTS Academic Article
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Radiation-induced DNA damage and the relative biological effectiveness of 18F-FDG in wild-type mice Academic Article
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Radiation-induced bystander effects and the DNA paradigm: An “out of field” perspective Academic Article
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Radiation-induced non-targeted effects: some open questions Academic Article
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Radiosensitization of glioma cells by modulation of Met signalling with the hepatocyte growth factor neutralizing antibody, AMG102 Academic Article
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Recharacterization of ancient DNA miscoding lesions: insights in the era of sequencing-by-synthesis Academic Article
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Recognition and repair of chemically heterogeneous structures at DNA ends Academic Article
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Reduced host cell reactivation of oxidative DNA damage in human cells deficient in the mismatch repair gene hMSH2 Academic Article
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Reduced host cell reactivation of oxidatively damaged DNA in ageing human fibroblasts Academic Article
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Relationship between clonogenic radiosensitivity, radiation-induced apoptosis and DNA damage/repair in human colon cancer cells Academic Article
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Renal excretion of 8-oxo-7,8-dihydro-2′-deoxyguanosine: degradation rates of RNA and metabolic rate in humans Academic Article
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Repair of Radiation-Induced DNA Breaks in Human Adenovirus Academic Article
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Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers Academic Article
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Research strategies for the prevention of early events in human radiation carcinogenesis Report on the 7th LH Gray Workshop held in the Radiation Science Centre, Dublin from 5th-8th December 1996 Academic Article
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Resistance exercise training decreases oxidative damage to DNA and increases cytochrome oxidase activity in older adults Academic Article
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Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene Academic Article
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Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects sperm from DNA damage and apoptosis caused by benzo(a)pyrene Academic Article
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Role of Fapy Glycosylase and UvrABC Excinuclease in the Repair of UVA (320-400 nm)-mediated DNA Damage in Escherichia coli Academic Article
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Role of RAD9-dependent cell-cycle checkpoints in the adaptive response to ionizing radiation in yeast, Saccharomyces cerevisiae Academic Article
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Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes Academic Article
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S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation Academic Article
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Skeletal Muscle Aging in F344BN F1-Hybrid Rats: I. Mitochondrial Dysfunction Contributes to the Age-Associated Reduction in VO2max Academic Article
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Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase Academic Article
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Structurally simplified biphenyl combretastatin A4 derivatives retain in vitro anti-cancer activity dependent on mitotic arrest Academic Article
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Structure-specific endonuclease activity of SNM1A enables processing of a DNA interstrand crosslink Academic Article
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Surveying the repair of ancient DNA from bones via high-throughput sequencing Academic Article
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Synergism between aphidicolin and adenoviruses in the induction of breaks at fragile sites on human chromosomes Academic Article
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Targets, pools, shoulders, and communication – a reflection on the evolution of low-dose radiobiology Academic Article
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Telomere crisis in kidney epithelial cells promotes the acquisition of a microRNA signature retrieved in aggressive renal cell carcinomas Academic Article
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The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis Academic Article
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The Genetic Secrets Some Fossils Hold Academic Article
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The Influence of Track Structure on the Understanding of Relative Biological Effectiveness for Induction of Chromosomal Exchanges in Human Lymphocytes Academic Article
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The Transcriptional Coactivator Yes-Associated Protein Drives p73 Gene-Target Specificity in Response to DNA Damage Academic Article
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The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites Academic Article
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The association between glutathione S-transferase M1 genotype and polycyclic aromatic hydrocarbon-DNA adducts in breast tissue. Academic Article
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The cellular environment in computer simulations of radiation-induced damage to DNA Academic Article
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The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: A possible molecular basis for the site-specific cancer risk modification Academic Article
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The p53/p21 DNA damage-signaling pathway is defective in most meningioma cells Academic Article
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The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults Academic Article
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The relationship between genetic damage from polycyclic aromatic hydrocarbons in breast tissue and breast cancer Academic Article
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The role of O6-alkylguanine-DNA alkyltransferase in protecting Rat4 cells against the mutagenic effects of O6-substituted guanine residues incorporated in codon 12 of the H-ras gene Academic Article
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The structure of DdrB from Deinococcus: a new fold for single-stranded DNA binding proteins Academic Article
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The transcriptionally competent U2 gene is necessary and sufficient for adenovirus type 12 induction of the fragile site at 17q21-22 Academic Article
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Transcriptomic Response in the Spleen after Whole-Body Low-Dose X-Ray Irradiation Academic Article
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UV-inducible base excision repair of oxidative damaged DNA in human cells Academic Article
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Ultrasound Imaging of Apoptosis: Spectroscopic Detection of DNA-Damage Effects In Vivo Academic Article
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Ultrasound Imaging of Apoptosis: Spectroscopic Detection of DNA-Damage Effects at High and Low Frequencies Academic Article
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Ultrasound Imaging of DNA-Damage Effects in Live Cultured Cells and in Brain Tissue Academic Article
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Unraveling the Complexities of DNA-Dependent Protein Kinase Autophosphorylation Academic Article
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Use of the Dual Potential to Rationalize the Occurrence of Some DNA Lesions (Pyrimidic Dimers) Academic Article
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Validated or Not Validated? That Is the Question Academic Article
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Variation in the expression of p53, c-myc, and bcl-2 oncoproteins in individual patient cultures of normal urothelium exposed to cobalt 60 gamma-rays and N-nitrosodiethanolamine. Academic Article
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Wild-type p53 modulates apoptosis of normal, IL-3 deprived, hematopoietic cells. Academic Article
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XRCC4's interaction with XLF is required for coding (but not signal) end joining Academic Article
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p73-Mediated Chemosensitivity: A Preferential Target of Oncogenic Mutant p53 Academic Article
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γ-H2AX as a Marker for Dose Deposition in the Brain of Wistar Rats after Synchrotron Microbeam Radiation Academic Article