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The cellular environment in computer simulations...
Journal article

The cellular environment in computer simulations of radiation-induced damage to DNA

Abstract

Abstract Radiation-induced DNA single- and double-strand breaks were modeled for 660 keV photon radiation and scavenger capacity mimicking the cellular environment. Atomistic representation of DNA in B form with a first hydration shell was utilized to model direct and indirect damage. Monte Carlo generated electron tracks were used to model energy deposition in matter and to derive initial spatial distributions of species which appear in the …

Authors

Moiseenko VV; Hamm RN; Waker AJ; Prestwich WV

Journal

Radiation and Environmental Biophysics, Vol. 37, No. 3, pp. 167–172

Publisher

Springer Nature

Publication Date

November 1998

DOI

10.1007/s004110050112

ISSN

0301-634X